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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SYHRFVEAGRLVYLGDGPDKGKLAVIVDILSTAAVLIDGPTTGVKRQVVSLRWAMLTDQVINISEKPTTEQLKKEIEASP
AIDTFMNSVWGKKIQQQRLRAKATFEDMGKIAKLRRERKMAMKRIAMS

The query sequence (length=128) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8br8:LN 130 128 1.0000 0.9846 1.0000 4.25e-92 8brm:LN, 8bsi:LN, 8bsj:LN, 8btd:LN, 8btr:LN, 8fru:M, 7pwg:M, 7pwo:M2
2 7oya:M1 134 117 0.3203 0.3060 0.3504 1.40e-21 7oyb:M1
3 7oyc:M1 134 117 0.3125 0.2985 0.3419 1.26e-20
4 5xxb:L 131 123 0.3516 0.3435 0.3659 8.00e-20
5 9bh5:CM 132 106 0.3125 0.3030 0.3774 1.84e-18 9cai:CM
6 8a3d:s 139 122 0.2969 0.2734 0.3115 6.32e-18 7a01:02, 5aj0:AM, 8b5l:M, 8b6c:M, 9bdl:AL14, 9bdn:AL14, 9bdp:AL14, 7bhp:LM, 8bhf:u3, 8bpo:L2, 8btk:BM, 7cpu:LM, 7cpv:LM, 4d5y:M, 4d67:M, 6d90:M, 6d9j:M, 9f1b:BM, 9f1c:BM, 9f1d:BM, 7f5s:LM, 8fkp:L8, 8fkq:L8, 8fkr:L8, 8fks:L8, 8fkt:L8, 8fku:L8, 8fkv:L8, 8fkw:L8, 8fkx:L8, 8fky:L8, 8fkz:L8, 8fl0:L8, 8fl2:L8, 8fl3:L8, 8fl4:L8, 8fl6:L8, 8fl7:L8, 8fl9:L8, 8fla:L8, 8flb:L8, 8flc:L8, 8fld:L8, 8fle:L8, 8flf:L8, 6frk:M, 6ftg:M, 6fti:M, 6ftj:M, 8g5y:LM, 8g5z:LM, 8g60:LM, 8g61:LM, 8g6j:LM, 8glp:LM, 6gz3:AM, 6gz4:AM, 6gz5:AM, 6hcf:M3, 6hcj:M3, 6hcm:M3, 6hcq:M3, 8idt:S, 8idy:S, 8ie3:S, 8ifd:2G, 8ife:2G, 8ine:S, 8inf:S, 8ink:S, 6ip5:2G, 6ip6:2G, 6ip8:2G, 8ipd:S, 8ipx:S, 8ipy:S, 8ir1:S, 8ir3:S, 3j7o:M, 3j7p:M, 3j7q:M, 3j7r:M, 3j92:M, 3jag:M, 3jah:M, 3jai:M, 3jaj:M, 3jan:M, 8jdj:R, 8jdk:R, 8jdl:R, 8jdm:R, 8k2c:LM, 5lks:LM, 6lqm:S, 6lsr:S, 6lss:S, 7ls1:G1, 7ls2:G1, 6lu8:S, 5lzs:M, 5lzt:M, 5lzu:M, 5lzv:M, 5lzw:M, 5lzx:M, 5lzy:M, 5lzz:M, 7mdz:M, 6mtb:M, 6mtc:M, 6mtd:M, 6mte:M, 7nfx:M, 7nwg:M3, 7nwh:M, 7nwi:M, 7o7y:BM, 7o7z:BM, 7o80:BM, 7o81:BM, 7obr:M, 8ohd:LM, 8oj0:LM, 8oj5:LM, 8oj8:LM, 6ole:N, 6olf:N, 6olg:AM, 6oli:N, 6olz:AM, 6om0:N, 6om7:N, 7ow7:s, 7oyd:M, 8p2k:BM, 6p5i:AM, 6p5j:AM, 6p5k:AM, 6p5n:AM, 8qfd:M, 7qgg:N, 8qoi:LM, 7qvp:LM, 7qvp:MM, 7qwq:M, 7qwr:M, 7qws:M, 6qzp:LM, 6r5q:M, 6r6g:M, 6r6p:M, 6r7q:M, 8rjb:M, 8rjc:M, 8rjd:M, 8scb:M, 6sgc:M2, 6swa:L, 5t2c:s, 6t59:M3, 7tm3:M, 7toq:AL14, 7tor:AL14, 7tut:M, 7ucj:M, 7uck:M, 4ug0:LM, 4ujc:BM, 4ujd:AM, 4uje:CM, 4v6x:CM, 6w6l:N, 6xa1:LM, 7xnx:LM, 7xny:LM, 8xsx:LM, 8xsy:LM, 8xsz:LM, 6y0g:LM, 8y0w:LM, 8y0x:LM, 6y2l:LM, 6y57:LM, 6y6x:LM, 8yoo:LM, 8yop:LM, 6z6l:LM, 6z6m:LM, 6z6n:LM, 7zjw:LP, 7zjx:LP, 6zm7:LM, 6zme:LM, 6zmi:LM, 6zmo:LM, 6zvk:Z2
7 4v6i:BN 138 124 0.3359 0.3116 0.3468 1.79e-17 8aaf:u, 8agt:u, 8agu:u, 8agv:u, 8agw:u, 8agx:u, 8agz:u, 5apn:M, 5apo:M, 7azy:N, 7b7d:LO, 8bip:LM, 8bjq:LM, 8bn3:M4, 8bqd:AM, 8bqx:AM, 7bt6:M, 7btb:M, 6c0f:M, 6cb1:M, 8ccs:PP, 8cdl:PP, 8cdr:PP, 8ceh:PP, 8cf5:PP, 8cg8:PP, 8cgn:PP, 8civ:PP, 8cku:PP, 8cmj:PP, 5dat:M4, 5dat:m4, 5dc3:M4, 5dc3:m4, 5dge:M4, 5dge:m4, 5dgf:M4, 5dgf:m4, 5dgv:M4, 5dgv:m4, 8e5t:M, 6elz:M, 6em1:M, 6em3:M, 6em4:M, 6em5:M, 8eub:AM, 8evp:AM, 8evq:AM, 8evr:AM, 8evs:AM, 8evt:AM, 8ewb:AM, 8ewc:AM, 5fci:M4, 5fci:m4, 5fcj:M4, 5fcj:m4, 6ft6:M, 5gak:O, 6gq1:M, 6gqb:M, 6gqv:M, 5h4p:M, 6hd7:O, 8hfr:MQ, 6hhq:u, 6hhq:CO, 5i4l:M4, 5i4l:m4, 6i7o:AM, 6i7o:XM, 3j6x:54, 3j6y:54, 3j77:64, 3j78:64, 3jct:M, 5jcs:M, 5juo:R, 5jup:R, 5jus:R, 5jut:R, 5juu:R, 8k2d:LM, 8k82:LM, 5lyb:M4, 5lyb:m4, 5m1j:M5, 6m62:M, 5mc6:AM, 5mei:u, 5mei:CO, 7mpi:AM, 7mpj:AM, 6n8j:M, 6n8k:M, 6n8l:M, 6n8m:O, 6n8n:O, 6n8o:O, 7n8b:AM, 7nac:M, 5ndg:M4, 5ndg:m4, 5ndv:M4, 5ndv:m4, 5ndw:M4, 5ndw:m4, 7nrc:LO, 7nrd:LO, 5obm:M4, 5obm:m4, 7of1:M, 7oh3:M, 7ohp:M, 7ohq:M, 7ohr:M, 7ohs:M, 7oht:M, 7ohu:M, 7ohv:M, 7ohw:M, 7ohx:M, 7ohy:M, 6oig:M, 5on6:u, 5on6:CO, 7osa:eL14, 7osm:eL14, 8p8m:JU, 8p8n:JU, 8p8u:JU, 8pfr:JU, 6q8y:AM, 6qik:M, 6qt0:M, 6qtz:M, 7r7a:M, 6r84:O, 6r86:O, 6r87:O, 6ri5:M, 7rr5:LM, 6rzz:M, 6s05:M, 6s47:AO, 6snt:s, 6sv4:AM, 6sv4:XM, 6sv4:zM, 6t4q:LM, 5t62:O, 5t6r:O, 6t7i:LM, 6t7t:LM, 6t83:My, 6t83:Oa, 5tbw:u, 5tbw:CO, 6tb3:AM, 5tga:M4, 5tga:m4, 5tgm:M4, 5tgm:m4, 6tnu:AM, 7too:AL14, 7top:AL14, 7u0h:M, 4u3m:M4, 4u3m:m4, 4u3n:M4, 4u3n:m4, 4u3u:M4, 4u3u:m4, 4u4n:M4, 4u4n:m4, 4u4o:M4, 4u4o:m4, 4u4q:M4, 4u4q:m4, 4u4r:M4, 4u4r:m4, 4u4u:M4, 4u4u:m4, 4u4y:M4, 4u4y:m4, 4u4z:M4, 4u4z:m4, 4u50:M4, 4u50:m4, 4u51:M4, 4u51:m4, 4u52:M4, 4u52:m4, 4u53:M4, 4u53:m4, 4u55:M4, 4u55:m4, 4u56:M4, 4u56:m4, 4u6f:M4, 4u6f:m4, 7ug6:M, 7uoo:M, 7uqb:M, 7uqz:M, 7v08:M, 4v7r:BN, 4v7r:DN, 4v88:BM, 4v88:DM, 4v8t:M, 4v8y:BM, 4v8z:BM, 8v83:M, 8v84:M, 8v87:M, 4v91:M, 6woo:M, 6xiq:M, 6xir:M, 8y0u:LM, 6ylg:M, 6ylh:M, 6ylx:M, 6yly:M, 5z3g:Q, 7z34:M, 6z6j:LM, 6z6k:LM, 7zpq:BL, 7zrs:BL, 7zs5:BN, 7zuw:BL, 7zux:EL, 7zw0:LP
8 8q7z:BM 130 122 0.2969 0.2923 0.3115 2.35e-17 8q87:BM
9 5it7:MM 136 124 0.3281 0.3088 0.3387 3.40e-17 6uz7:AM
10 8tpu:AN 147 125 0.3438 0.2993 0.3520 1.04e-16 3j79:N, 3jbn:AN, 3jbo:AN, 3jbp:AN, 5umd:N
11 8esq:M 125 118 0.2812 0.2880 0.3051 2.71e-15 8esr:M, 8etc:M, 8etg:M, 8eth:M, 8eti:M, 8etj:M, 8eug:M, 8eui:M, 8eup:M, 8euy:M, 8ev3:M
12 4v8p:AF 125 93 0.2812 0.2880 0.3871 4.00e-14 4v8p:DF, 4v8p:FF, 4v8p:HF
13 4v3p:LN 134 117 0.3203 0.3060 0.3504 8.34e-14 8ip8:XA, 8ipa:XA, 8ipb:XA, 8jiv:CM, 4v7e:CM
14 7qiw:O 132 117 0.3125 0.3030 0.3419 3.20e-13 8azw:E, 8b2l:E3, 7qiz:O
15 4v6w:CM 159 117 0.3047 0.2453 0.3333 2.03e-11 6xu6:CM, 6xu7:CM, 6xu8:CM
16 7r81:O1 141 125 0.3438 0.3121 0.3520 3.48e-10
17 8c3a:u 130 122 0.2969 0.2923 0.3115 9.41e-09 8c3a:BH, 8cq7:u, 8cq7:BH, 8cqw:u, 8cqw:BH, 8cre:u, 8cre:BH, 8oeq:u, 8oeq:BH, 7pzy:u, 7q08:u, 7q0f:u, 7q0p:u, 7q0r:u, 8q5i:u
18 7olc:LM 141 122 0.3281 0.2979 0.3443 1.82e-08 8i9p:LM, 8i9r:LM, 8i9t:LM, 8i9v:LM, 8i9w:LM, 8i9x:LM, 8i9y:LM, 8i9z:LM, 8ia0:LM, 7old:LM, 8oo0:LM, 8pv1:LM, 8pv2:LM, 8pv3:LM, 8pv4:LM, 8pv5:LM, 8pv6:LM, 8pv7:LM, 8pv8:LM, 8pvk:LM, 8pvl:LM, 7z3n:LM, 7z3o:LM
19 8hku:L141 86 80 0.2266 0.3372 0.3625 2.99e-08 8hku:L142, 8hkv:L141, 8hkv:L142, 8hky:L141, 8hky:L142, 8hkz:L141, 8hkz:L142, 8hl1:L141, 8hl1:L142, 8hl2:L141, 8hl2:L142, 8hl3:L141, 8hl3:L142, 8hl4:L141, 8hl4:L142, 8hl5:L141, 8hl5:L142
20 5xy3:M 124 117 0.2812 0.2903 0.3077 1.97e-07
21 6zj3:LZ 217 116 0.2266 0.1336 0.2500 7.32e-07
22 4v8m:BP 183 82 0.1875 0.1311 0.2927 1.09e-06 8ova:BP, 8ove:BP
23 3jcs:K 156 115 0.2188 0.1795 0.2435 1.33e-06
24 8ovj:K 170 115 0.2188 0.1647 0.2435 3.22e-06 8a3w:K, 8a98:K, 6az3:K, 8rxh:LK, 8rxx:LK, 5t2a:N
25 5t5h:P 149 104 0.2109 0.1812 0.2596 7.05e-05
26 1pgu:B 608 46 0.1328 0.0280 0.3696 0.34 1pgu:A, 1pi6:A
27 6skf:BM 81 75 0.1484 0.2346 0.2533 0.51 6skf:BN, 6skg:BM, 6skg:BN, 6th6:BM, 6th6:BN
28 7aih:Aw 185 24 0.0859 0.0595 0.4583 0.96 7am2:Aw, 7ane:Aw
29 7pkt:s 210 32 0.1016 0.0619 0.4062 1.4
30 4v4n:A5 81 73 0.1484 0.2346 0.2603 1.7 4v4n:AK, 4v6u:B5, 4v6u:BK
31 8ek9:A 266 101 0.2109 0.1015 0.2673 2.2
32 3j79:I 207 54 0.1172 0.0725 0.2778 3.1 3jbn:AI, 3jbo:AI, 3jbp:AI, 8tpu:AI, 5umd:I
33 6uij:A 620 58 0.1484 0.0306 0.3276 4.1 9cbf:A, 9cbg:A, 9cbi:A, 9cbj:A, 6uhv:A, 6uii:A, 6uil:A, 6uim:A
34 7r81:H1 194 58 0.1250 0.0825 0.2759 4.5
35 5ze0:N 118 51 0.1328 0.1441 0.3333 5.1 1ckt:A
36 4v6w:CE 228 73 0.1406 0.0789 0.2466 5.6 6xu6:CE, 6xu7:CE, 6xu8:CE
37 6cij:N 133 49 0.1406 0.1353 0.3673 5.7 5zdz:N, 5ze1:N, 5ze2:N
38 7zq5:u 91 48 0.1172 0.1648 0.3125 5.8 7zq6:u
39 4qr9:A 75 51 0.1328 0.2267 0.3333 6.0 4qr9:B
40 2dw6:A 388 27 0.0781 0.0258 0.3704 6.2 2dw6:B, 2dw6:C, 2dw6:D, 2dw7:A, 2dw7:B, 2dw7:C, 2dw7:D, 2dw7:E, 2dw7:F, 2dw7:G, 2dw7:H, 2dw7:I, 2dw7:J, 2dw7:K, 2dw7:L, 2dw7:M, 2dw7:N, 2dw7:O, 2dw7:P, 1tzz:A, 1tzz:B
41 8iwp:A 896 49 0.1406 0.0201 0.3673 7.9 8iwr:A, 8iws:A, 8iwt:A, 8iwu:A, 8iww:A, 7yag:A, 7yah:A, 7yai:A, 7yaj:A, 7yam:A
42 7e7q:A 1958 41 0.1016 0.0066 0.3171 9.5
43 4q2d:A 927 92 0.1875 0.0259 0.2609 10.0

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218