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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SYGSRIEREQHHLIESIEKSTQYMAKRRIGALISVARDTGMDDYIETGIPLNAKISSQLLINIFIPNTPLHDGAVIIKGN
EIASAASYLPLSDSPFLSKELGTRHRAALGISEVTDSITIVVSEETGGISLTKGGELFRDVSEEELHKILLKELV

The query sequence (length=155) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6hvn:A 175 155 0.9935 0.8800 0.9935 1.86e-108 8c4j:A, 8c4j:B, 8c4m:A, 8c4n:A, 8c4n:B, 8c4o:A, 8c4o:B, 8c4p:A, 8c4p:B, 8c4r:A, 6hvl:A, 6hvl:B, 6hvm:B, 4rv7:A, 4rv7:B, 4rv7:C, 4rv7:D, 8s45:B, 8s46:B, 8s47:A, 8s47:B, 8s48:B, 8s49:B, 8s4a:A, 8s4a:B, 8s4b:B
2 8ogp:A 153 149 0.6839 0.6928 0.7114 5.14e-77 8ogn:A, 8ogo:A, 8ogq:A, 8ogr:B, 8ogs:A, 8ogs:B, 8ogt:A, 8ogu:A, 8ogv:A, 8ogw:A, 8ogw:B, 8ogy:A, 8ogz:B, 8oh0:A, 8oh0:B, 8oh1:A, 8ohb:A, 8ohb:B, 8ohc:B, 8ohe:A, 8ohf:A, 8ohf:B, 8ohg:A, 8ohh:A, 8ohj:B, 8ohk:A, 8ohl:A, 8oho:A, 8oho:B
3 6gyx:B 152 143 0.5871 0.5987 0.6364 8.02e-65 6gyx:A
4 8ofg:A 151 146 0.5290 0.5430 0.5616 1.03e-53 8ofg:B
5 7l8n:A 151 141 0.5097 0.5232 0.5603 4.10e-53
6 7dg0:A 155 145 0.3742 0.3742 0.4000 1.34e-33 7dg0:B
7 3c1y:A 349 106 0.2065 0.0917 0.3019 0.024 3c1y:B, 3c21:A, 3c21:B, 3c23:A, 3c23:B, 4yvz:A, 4yvz:B, 4yxj:A, 4yxj:B, 4yxm:A, 4yxm:B
8 3o78:A 402 71 0.1548 0.0597 0.3380 0.62 7aug:A, 3ek4:A, 3ek7:A, 3ek8:A, 3ekh:A, 3evr:A, 3evu:A, 3evv:A, 4ik1:A, 4ik3:A, 4ik4:A, 4ik5:A, 4ik8:A, 4ik9:A, 3o77:A, 3o78:B, 3sg2:A, 3sg3:A, 3sg4:A, 3sg5:A, 3sg6:A, 3sg7:A, 7st4:A, 6tv7:A, 3wlc:A, 3wld:A, 6ya9:A, 6zsm:A, 6zsn:A
9 7k44:A 356 46 0.1032 0.0449 0.3478 1.2
10 3osq:A 607 108 0.2129 0.0544 0.3056 2.8
11 4z4k:A 282 55 0.1161 0.0638 0.3273 3.2 5aas:A, 4bmj:A, 4bmj:B, 4bmj:D, 4bmj:E, 4bmj:F, 4bmj:G, 4bmj:I, 4bmj:K, 3vht:B, 5yt6:D, 4z4k:B, 4z4m:A, 4z4m:B
12 3u8p:A 336 55 0.1161 0.0536 0.3273 3.3 3c63:A, 3c63:B, 3c63:C, 3c63:D, 8drj:A, 6dy8:A, 6dy8:B, 6dy8:D, 6dy8:C, 6dyf:A, 6dyf:B, 6dyg:A, 6dyg:B, 6dyh:A, 6dyh:D, 7lr5:C, 7lr5:A, 7lra:C, 7lra:A, 7lrb:A, 7lrb:B, 7lrr:A, 7lrr:B, 7lrv:C, 7lrv:A, 7lv1:C, 7lv1:A, 7lv4:C, 7lv4:A, 7mk4:A, 7mk4:B, 7n4f:C, 7n4f:A, 7n4g:C, 7n4g:A, 3u8p:B, 3u8p:C, 6wyu:A, 6wyu:B, 6wyu:C, 6wz0:A, 6wz0:B, 6wz0:C
13 2ix1:A 643 44 0.0903 0.0218 0.3182 3.9 2id0:A, 2id0:B, 2id0:C, 2id0:D, 2ix0:A
14 7lh5:CC 207 59 0.1226 0.0918 0.3220 4.2 5a9z:BG, 5aa0:BG, 4aqy:C, 7azo:S3A, 7azo:S3B, 7azs:S3A, 7azs:S3B, 9b00:1c, 9b00:2c, 4b3m:C, 4b3r:C, 4b3s:C, 4b3t:C, 6b4v:LA, 6b4v:PC, 6boh:MA, 6boh:RC, 6bok:KA, 6bok:NC, 5br8:C, 6buw:QC, 6buw:XC, 6bz6:QC, 6bz6:XC, 6bz7:QC, 6bz7:XC, 6bz8:QC, 6bz8:XC, 6c5l:AC, 6c5l:CC, 6cae:1c, 6cae:2c, 6cao:C, 6cap:C, 6caq:C, 6car:C, 6cas:C, 6cfj:1c, 6cfj:2c, 6cfk:1c, 6cfk:2c, 6cfl:1c, 6cfl:2c, 8cvj:1c, 8cvj:2c, 8cvk:1c, 8cvk:2c, 8cvl:1c, 8cvl:2c, 5czp:XC, 5czp:QC, 6czr:1c, 6czr:2c, 5d8b:DA, 5d8b:ZB, 5dfe:XC, 5dfe:QC, 5dox:1c, 5dox:2c, 5doy:1c, 5doy:2c, 4dr1:C, 4dr2:C, 4dr3:C, 4dr4:C, 4dr5:C, 4dr6:C, 4dr7:C, 6dti:C, 4duy:C, 4duz:C, 7dug:C, 7duh:C, 7dui:C, 7duj:C, 7duk:C, 7dul:C, 4dv0:C, 4dv1:C, 4dv2:C, 4dv3:C, 4dv4:C, 4dv5:C, 4dv6:C, 4dv7:C, 2e5l:C, 5e7k:2E, 5e7k:22, 5e81:2E, 5e81:22, 8ekb:1c, 8ekb:2c, 5el4:2E, 5el4:22, 5el5:2E, 5el5:22, 5el6:2E, 5el6:22, 5el7:2E, 5el7:22, 8ev6:1c, 8ev6:2c, 8ev7:1c, 8ev7:2c, 2f4v:C, 5f8k:1c, 5f8k:2c, 8fc1:1c, 8fc1:2c, 8fc2:1c, 8fc2:2c, 8fc3:1c, 8fc3:2c, 8fc4:1c, 8fc4:2c, 8fc5:1c, 8fc5:2c, 8fc6:1c, 8fc6:2c, 5fdu:1c, 5fdu:2c, 5fdv:1c, 5fdv:2c, 1fjg:C, 6fkr:1c, 6fkr:2c, 8fom:QC, 8fom:XC, 8fon:QC, 8fon:XC, 8g29:1c, 8g29:2c, 8g2a:1c, 8g2a:2c, 8g2b:1c, 8g2b:2c, 8g2c:1c, 8g2c:2c, 8g2d:1c, 8g2d:2c, 4gkj:C, 4gkk:C, 6gsj:2E, 6gsj:22, 6gsk:2E, 6gsk:22, 6gsl:2E, 6gsl:22, 6gzq:C2, 6gzx:C3, 6gzx:C4, 6gzz:C3, 6gzz:C4, 5hau:1c, 5hau:2c, 5hcp:1c, 5hcp:2c, 5hcq:1c, 5hcq:2c, 5hcr:1c, 5hcr:2c, 5hd1:1c, 5hd1:2c, 2hhh:C, 1hnw:C, 1hnx:C, 1hnz:C, 1hr0:C, 1i94:C, 1i95:C, 1i96:C, 1i97:C, 1ibk:C, 1ibl:C, 1ibm:C, 5ib7:2E, 5ib7:22, 5ib8:2E, 5ib8:22, 5ibb:2E, 5ibb:22, 5imq:G, 5imr:G, 5iwa:C, 5j30:QC, 5j30:XC, 5j3c:QC, 5j3c:XC, 5j4b:1c, 5j4b:2c, 5j4c:1c, 5j4c:2c, 5j4d:LA, 5j4d:QC, 1j5e:C, 5j8b:c, 4ji0:C, 4ji1:C, 4ji2:C, 4ji3:C, 4ji4:C, 4ji5:C, 4ji6:C, 4ji7:C, 4ji8:C, 7jql:1c, 7jql:2c, 7jqm:1c, 7jqm:2c, 4jv5:C, 4jya:C, 4k0k:C, 4khp:C, 4kvb:C, 4l47:QC, 4l47:XC, 4l71:QC, 4l71:XC, 4lel:QC, 4lel:XC, 4lf4:C, 4lf5:C, 4lf6:C, 4lf7:C, 4lf8:C, 4lf9:C, 4lfa:C, 4lfb:C, 4lfc:C, 4lfz:QC, 4lfz:XC, 7lh5:AC, 5lmn:C, 5lmo:C, 5lmp:C, 5lmq:C, 5lmr:C, 5lms:C, 5lmt:C, 5lmu:C, 5lmv:C, 4lnt:QC, 4lnt:XC, 4lsk:QC, 4lsk:XC, 4lt8:QC, 4lt8:XC, 7md7:1c, 7md7:2c, 6mkn:C, 6mpf:C, 6mpi:C, 6n1d:AS03, 6n1d:BS03, 1n32:C, 1n33:C, 1n34:C, 1n36:C, 6n9e:1c, 6n9e:2c, 6n9f:1c, 6n9f:2c, 5ndj:2E, 5ndj:22, 5ndk:2E, 5ndk:22, 6nd5:1c, 6nd5:2c, 6nd6:1c, 6nd6:2c, 6ndk:QC, 6ndk:XC, 6nsh:QC, 6nsh:XC, 6nta:QC, 6nta:XC, 6nuo:QC, 6nuo:XC, 6nwy:QC, 6nwy:XC, 4nxm:C, 4nxn:C, 6ny6:C, 6o3m:QC, 6o3m:XC, 6o97:1c, 6o97:2c, 6of1:1c, 6of1:2c, 6of6:QC, 6of6:XC, 6oj2:QC, 6oj2:XC, 6ope:QC, 6ope:XC, 6ord:QC, 6ord:XC, 6osi:QC, 6osi:XC, 3oto:C, 5ot7:B, 6otr:QC, 6otr:XC, 4ox9:C, 6oxa:QC, 6oxa:XC, 6oxi:QC, 6oxi:XC, 4p6f:QC, 4p6f:XC, 4p70:QC, 4p70:XC, 6q95:h, 6qnq:2E, 6qnq:22, 6qnr:2E, 6qnr:22, 7rq8:1c, 7rq8:2c, 7rq9:1c, 7rq9:2c, 7rqa:1c, 7rqa:2c, 7rqb:1c, 7rqb:2c, 7rqc:1c, 7rqc:2c, 7rqd:1c, 7rqd:2c, 7rqe:1c, 7rqe:2c, 3t1h:C, 3t1y:C, 8t8b:1c, 8t8b:2c, 8t8c:1c, 8t8c:2c, 4tua:QC, 4tua:XC, 4tub:QC, 4tub:XC, 4tuc:QC, 4tuc:XC, 4tud:QC, 4tud:XC, 4tue:QC, 4tue:XC, 7u2h:1c, 7u2h:2c, 7u2i:1c, 7u2i:2c, 7u2j:1c, 7u2j:2c, 6ucq:1c, 6ucq:2c, 8ud6:1c, 8ud6:2c, 8ud7:1c, 8ud7:2c, 8ud8:1c, 8ud8:2c, 6uo1:1c, 6uo1:2c, 5uq7:c, 5uq8:c, 2uu9:C, 2uua:C, 2uub:C, 2uuc:C, 8uvr:1c, 8uvr:2c, 8uvs:1c, 8uvs:2c, 2uxb:C, 2uxc:C, 2uxd:C, 7v2l:C, 7v2m:C, 7v2n:C, 7v2o:C, 7v2p:C, 7v2q:C, 4v49:AC, 4v4a:AC, 4v4g:AC, 4v4g:CC, 4v4g:EC, 4v4g:GC, 4v4g:IC, 4v4i:d, 4v4j:d, 4v4p:BF, 4v4r:AC, 4v4s:AC, 4v4t:AC, 4v4x:AF, 4v4y:AF, 4v4z:AF, 4v51:AC, 4v51:CC, 4v5a:AC, 4v5a:CC, 4v5c:AC, 4v5c:CC, 4v5d:AC, 4v5d:CC, 4v5e:AC, 4v5e:CC, 4v5f:AC, 4v5f:CC, 4v5g:AC, 4v5g:CC, 4v5j:AC, 4v5j:CC, 4v5k:AC, 4v5k:CC, 4v5l:AC, 4v5m:AC, 4v5n:AC, 4v5p:AC, 4v5p:CC, 4v5q:AC, 4v5q:CC, 4v5r:AC, 4v5r:CC, 4v5s:AC, 4v5s:CC, 4v63:AC, 4v63:CC, 4v67:AC, 4v67:CC, 4v68:AC, 4v6a:AC, 4v6a:CC, 4v6f:BF, 4v6f:CF, 4v6g:AF, 4v6g:CF, 4v7j:Ac, 4v7j:Bc, 4v7k:Ac, 4v7k:Bc, 4v7l:AC, 4v7l:CC, 4v7m:AC, 4v7m:CC, 4v7p:AC, 4v7p:DC, 4v7w:AC, 4v7w:CC, 4v7x:AC, 4v7x:CC, 4v7y:AC, 4v7y:CC, 4v7z:AC, 4v7z:CC, 4v83:AC, 4v83:CC, 4v84:AC, 4v84:CC, 4v87:BF, 4v87:CF, 4v8a:CC, 4v8a:DC, 4v8b:AF, 4v8b:CF, 4v8c:CF, 4v8c:DF, 4v8d:AF, 4v8d:CF, 4v8e:BF, 4v8e:DF, 4v8f:BF, 4v8f:CF, 4v8g:AC, 4v8g:CC, 4v8h:AC, 4v8h:CC, 4v8i:AC, 4v8i:CC, 4v8j:AC, 4v8j:CC, 4v8n:AC, 4v8n:CC, 4v8o:AC, 4v8q:BC, 4v8u:AC, 4v8u:CC, 4v8x:AC, 4v8x:CC, 5v8i:1c, 5v8i:2c, 4v90:AC, 4v95:AC, 4v95:CC, 4v97:AC, 4v97:CC, 4v9a:AF, 4v9a:CF, 4v9b:AF, 4v9b:CF, 4v9h:AC, 4v9i:AC, 4v9i:CC, 4v9j:AC, 4v9j:CC, 4v9k:AC, 4v9k:CC, 4v9l:AC, 4v9l:CC, 4v9m:AC, 4v9m:CC, 4v9n:AC, 4v9n:CC, 4v9q:BC, 4v9q:DC, 4v9r:AC, 4v9r:CC, 4v9s:AC, 4v9s:CC, 5vp2:1c, 5vp2:2c, 5vpo:QC, 5vpo:XC, 5vpp:QC, 5vpp:XC, 2vqe:C, 2vqf:C, 8vtu:1c, 8vtu:2c, 8vtv:1c, 8vtv:2c, 8vtw:1c, 8vtw:2c, 8vtx:1c, 8vtx:2c, 8vty:1c, 8vty:2c, 1vvj:QC, 1vvj:XC, 1vy4:AC, 1vy4:CC, 1vy5:AC, 1vy5:CC, 1vy6:AC, 1vy6:CC, 1vy7:AC, 1vy7:CC, 4w29:AC, 4w29:CC, 4w2e:c, 4w2f:AC, 4w2f:CC, 4w2g:AC, 4w2g:CC, 4w2h:AC, 4w2h:CC, 4w2i:AC, 4w2i:CC, 4w4g:QC, 4w4g:XC, 5w4k:1c, 5w4k:2c, 5wis:1c, 5wis:2c, 5wit:1c, 5wit:2c, 5wnp:C, 5wnq:C, 5wnr:C, 5wns:C, 5wnt:C, 5wnu:C, 5wnv:C, 4wpo:BC, 4wpo:DC, 4wq1:2E, 4wq1:22, 4wqf:BC, 4wqf:DC, 4wqr:2E, 4wqr:22, 4wqu:BC, 4wqu:DC, 4wqy:BC, 4wqy:DC, 4wr6:2E, 4wr6:22, 4wra:2E, 4wra:22, 4wro:2E, 4wro:22, 4wsd:2E, 4wsd:22, 4wsm:2E, 4wsm:22, 4wt1:2E, 4wt1:22, 4wt8:AC, 4wt8:BC, 4wu1:2E, 4wu1:22, 4wzd:2E, 4wzd:22, 4wzo:2E, 4wzo:22, 4x62:C, 4x64:C, 4x65:C, 4x66:C, 4xej:AS03, 4xej:BS03, 6xhv:1c, 6xhv:2c, 6xhw:1c, 6xhw:2c, 6xhx:1c, 6xhx:2c, 6xhy:1c, 6xhy:2c, 1xmo:C, 1xmq:C, 1xnq:C, 1xnr:C, 6xqd:1c, 6xqd:2c, 6xqe:1c, 6xqe:2c, 4y4o:1c, 4y4o:2c, 4y4p:1c, 4y4p:2c, 4yhh:C, 4ypb:QC, 4ypb:XC, 4yy3:C, 4yzv:QC, 4yzv:XC, 4z3s:1c, 4z3s:2c, 4z8c:1c, 4z8c:2c, 4zer:1c, 4zer:2c, 5zlu:I, 2zm6:C, 4zsn:QC, 4zsn:XC
15 8b6s:A 517 55 0.1161 0.0348 0.3273 4.7 8b6r:A, 8b6s:B, 8b6t:A, 8b6t:B, 1cqw:A, 4fwb:A, 4hzg:A, 8j1o:A, 4kac:A, 4kac:B, 4kaj:A, 4kyv:A, 4kyv:B, 7o3o:A, 7o8b:A, 7ond:A, 7ond:B, 7oo4:A, 7pcw:A, 7pcw:B, 7pcw:C, 7pcw:D, 7pcx:A, 7pcx:B, 7pcx:F, 7pcx:C, 7pcx:D, 7pcx:E, 3rk4:A, 8sw8:AAA, 6u32:A, 5uxz:A, 5uxz:B, 5vnp:A, 5vnp:B, 7wam:A, 7wan:A, 5y2y:A, 5y2y:B, 6y7a:A, 6y7b:A, 6y7b:B, 6y7b:E, 6y7b:C, 6y7b:D, 7zba:A, 7zba:B, 7zbb:A, 7zbb:B, 7zbd:A, 7zbd:B, 6zcc:A, 7ziv:A, 7ziw:A, 7ziw:B, 7zix:A, 7zix:B, 7ziy:A, 7ziy:B, 7ziz:A, 7zj0:A, 7zj0:B, 6zvu:A, 6zvv:A, 6zvv:B, 6zvv:C, 6zvv:D, 6zvw:A, 6zvw:B, 6zvx:A, 6zvy:A, 6zvy:B
16 4k49:C 136 48 0.0903 0.1029 0.2917 4.7 4k49:B, 4k49:D, 4k49:A, 4k4a:A, 4k4a:B, 4k4a:D, 4k4a:C, 4k4b:A, 4k4b:B, 4k4b:C, 4k4b:D, 4k4b:E, 4k4b:F, 4k4b:G, 4k4b:H
17 6hr1:A 406 55 0.1161 0.0443 0.3273 5.1 6hr1:B
18 4pos:J 274 52 0.1097 0.0620 0.3269 5.3 4por:B, 4por:A, 4por:C, 4por:D, 4por:E, 4por:F, 4por:H, 4por:G, 4por:I, 4por:J, 4pos:B, 4pos:A, 4pos:C, 4pos:E, 4pos:D, 4pos:G, 4pos:F, 4pos:H, 4pos:I, 4pot:B, 4pot:A, 4pot:C, 4pot:D, 4pot:E, 4pot:G, 4pot:F, 4pot:H, 4pot:I, 4pot:J
19 8smu:D 394 55 0.1161 0.0457 0.3273 5.3 8smu:A, 8smu:C, 8smu:B
20 4qd8:C 139 71 0.1097 0.1223 0.2394 5.6 4qd8:E, 4qd8:F, 4qd8:D, 4qd9:C, 4qd9:D, 4qd9:F, 4qd9:E
21 1b9h:A 384 47 0.0839 0.0339 0.2766 7.1 1b9i:A
22 7ydq:A 598 55 0.1161 0.0301 0.3273 9.1 4as8:A, 2b3q:A, 2b3q:D, 8dhy:A, 8dpd:A, 4eul:A, 6gqg:A, 6ir7:A, 4jfg:A, 4jfg:B, 4jfg:C, 4jfg:D, 4jfg:E, 4jfg:F, 4jfg:G, 4jfg:H, 6jgj:A, 4ka9:A, 4kw9:A, 1kyr:A, 1kys:A, 4l1i:A, 5nhn:B, 5nhn:A, 5ni3:A, 5ni3:D, 5ni3:B, 5ni3:C, 2o24:A, 7pca:A, 6sm0:A, 5t3i:A, 4w7c:D, 4w7e:A
23 7bvy:A 333 61 0.1161 0.0541 0.2951 9.3 7bvz:A
24 4anj:A 995 55 0.1161 0.0181 0.3273 9.3 1jbz:A
25 7s7t:A 509 106 0.2000 0.0609 0.2925 9.8 8i4o:A, 8i4o:C, 8i4o:E, 8i4o:G, 8i4o:I, 8i4o:K

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218