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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SVRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVAQWMIQQPHK
AATFFGCIGIDKFGEILKRKAAEAHVDAHYYEQNEQPTGTCAACITGDNRSLIANLAAANCYKKEKHLDLEKNWMLVEKA
RVCYIAGFFLTVSPESVLKVAHHASENNRIFTLNLSAPFISQFYKESLMKVMPYVDILFGNETEAATFAREQGFETKDIK
EIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRA
GHYAASIIIRRTGCTFPEKPDFH

The query sequence (length=343) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2i6a:A 343 343 1.0000 1.0000 1.0000 0.0 1bx4:A, 2i6a:B, 2i6a:C, 2i6a:D, 2i6b:A, 2i6b:B, 5kb5:A, 5kb6:A, 5kb6:B, 4o1l:A, 4o1l:B
2 3loo:B 341 343 0.5073 0.5103 0.5073 9.19e-126 3loo:A, 3loo:C
3 4n09:A 345 333 0.3965 0.3942 0.4084 3.74e-84 4n09:B, 4n09:C, 4n09:D, 3otx:A, 3otx:B, 2xtb:A
4 3uq6:A 345 346 0.3819 0.3797 0.3786 6.32e-76 4dc3:A, 4dc3:B, 3uq6:B, 3uq9:A, 3uq9:B, 3vaq:A, 3vaq:B, 3vas:A, 3vas:B
5 2a9y:A 351 347 0.3265 0.3191 0.3228 9.65e-50 2a9z:A, 2aa0:A, 2ab8:A, 2abs:A, 1dgm:A, 1lii:A, 1lij:A, 1lik:A
6 3ubo:A 338 337 0.2536 0.2574 0.2582 1.06e-15 3ubo:B
7 4k8p:A 332 335 0.2507 0.2590 0.2567 1.10e-15 4e3a:A, 4e3a:B, 4jks:A, 4jks:B, 4jku:A, 4jku:B, 4k8c:A, 4k8c:B, 4k8k:A, 4k8k:B, 4k8p:B, 4k8t:A, 4k8t:B, 4k93:A, 4k93:B, 4k9c:A, 4k9c:B, 4k9i:A, 4k9i:B, 4kad:A, 4kad:B, 4kah:A, 4kah:B, 4kal:A, 4kal:B, 4kan:A, 4kan:B, 4kbe:A, 4kbe:B, 4lbg:A, 4lbg:B, 4lbx:A, 4lbx:B, 4lc4:A, 4lc4:B, 4lca:A, 4lca:B
8 1gqt:B 307 260 0.2070 0.2313 0.2731 2.33e-11 1gqt:A, 1gqt:C, 1gqt:D, 1rk2:A, 1rk2:B, 1rk2:C, 1rk2:D, 1rkd:A, 1rks:A
9 2c49:A 299 281 0.1837 0.2107 0.2242 1.66e-09 2c49:B
10 6wb7:A 296 89 0.0933 0.1081 0.3596 1.21e-08 6wb7:B, 6wb7:C, 6wb7:D
11 6ils:B 313 275 0.1895 0.2077 0.2364 4.38e-08 6ils:A, 6ilt:A, 6ilt:B
12 8cqx:A 300 308 0.2041 0.2333 0.2273 4.61e-07 8cqx:B, 8cqx:C, 8cqx:D, 6znx:A, 6znx:B, 6znx:D
13 5c41:A 317 264 0.1749 0.1893 0.2273 5.55e-07 5byf:A, 5byf:B, 5c3y:A, 5c3y:B, 5c3y:C, 5c3y:D, 5c3y:E, 5c3y:F, 5c3y:G, 5c3y:H, 5c3y:I, 5c3y:J, 5c3y:K, 5c3y:L, 5c3z:A, 5c3z:B, 5c40:A, 5c40:B, 5c41:B, 5c41:C, 5c41:D, 2fv7:A, 2fv7:B, 6wjz:A, 6wjz:B, 6wk0:A, 6wk0:B, 6wk0:C, 6wk0:D
14 6znx:C 265 293 0.2041 0.2642 0.2389 2.24e-06
15 3in1:A 312 300 0.2070 0.2276 0.2367 7.04e-06 3in1:B
16 1v1a:A 301 281 0.1895 0.2159 0.2313 1.59e-05 1v1a:B, 1v1b:A, 1v1b:D, 1v1b:B, 1v1b:C
17 4xck:A 306 254 0.1895 0.2124 0.2559 8.01e-05 4xck:B, 4xck:C, 4xck:D, 4xda:A, 4xda:B, 4xda:C, 4xda:D
18 6a8a:A 327 144 0.1108 0.1162 0.2639 8.95e-05 6a8a:B, 6a8b:A, 6a8b:B, 6a8c:A, 6a8c:B, 5zwy:A, 5zwy:B
19 3ih0:A 304 261 0.1778 0.2007 0.2337 1.46e-04 3gbu:A, 3gbu:B, 3gbu:C, 3gbu:D
20 3kd6:A 300 171 0.1224 0.1400 0.2456 7.51e-04 3kd6:B
21 6vwp:A 435 239 0.1545 0.1218 0.2218 0.004 6vwo:A, 6vwp:B, 6vwp:C, 6vwp:D, 6vwp:E, 6vwp:F, 6vwp:G, 6vwp:H
22 2var:A 311 285 0.1808 0.1994 0.2175 0.044 2var:B, 2var:C
23 6xk2:A 320 47 0.0496 0.0531 0.3617 0.048 6xk2:B, 6xk2:C, 6xk2:D
24 3ie7:A 309 43 0.0466 0.0518 0.3721 0.098 3jul:A
25 1tz3:A 299 20 0.0379 0.0435 0.6500 0.35 1tz6:A, 1tz6:B
26 4e84:A 313 47 0.0379 0.0415 0.2766 0.42 4e84:B, 4e8w:A, 4e8w:B, 4e8y:A, 4e8y:B, 4e8z:A, 4e8z:B
27 4wjm:A 312 299 0.2012 0.2212 0.2308 0.71
28 7ag6:A 302 45 0.0437 0.0497 0.3333 0.82 7ag6:B, 7agh:C, 7agh:D, 7agh:A, 7agh:B, 7agk:A, 7agk:B, 7agk:C
29 5ygg:A 310 50 0.0525 0.0581 0.3600 0.86 5eyn:A, 5f0z:A, 5f11:A
30 3ktn:A 340 174 0.1050 0.1059 0.2069 1.2
31 6wb4:B 306 18 0.0292 0.0327 0.5556 2.3 6wb4:A, 6wb5:A, 6wb5:B
32 7fca:D 282 21 0.0321 0.0390 0.5238 3.6 7cf8:A, 7cf8:E, 7fca:A, 7fca:E
33 2w3z:A 238 34 0.0437 0.0630 0.4412 4.3
34 8v3w:H 581 20 0.0321 0.0189 0.5500 4.5 8v3w:x, 8v3w:b
35 4idb:A 321 49 0.0525 0.0561 0.3673 5.7 4idc:A, 4idd:A, 4ide:A, 4idf:A
36 3vnp:A 171 32 0.0379 0.0760 0.4062 7.0 3vnp:B, 3vnp:C
37 3lki:B 322 17 0.0321 0.0342 0.6471 7.5
38 4gw9:A 628 29 0.0321 0.0175 0.3793 8.0 4gw9:B, 4gw9:C, 4gw9:D, 5oy5:A, 5vik:A, 5viq:A, 5viv:A, 4xtq:A
39 3din:A 816 95 0.0758 0.0319 0.2737 8.2 3din:B, 3jux:A, 4ys0:A
40 6c9r:A 337 42 0.0408 0.0415 0.3333 8.5 6c67:A, 6c67:B, 6c9n:A, 6c9n:B, 6c9p:A, 6c9p:B, 6c9q:A, 6c9r:B, 6c9s:A, 6c9s:B, 6c9v:A, 6c9v:B, 4o1g:A, 2pkk:A, 2pkm:A, 2pkn:A, 4pvv:A, 4ube:A
41 6ekc:B1 73 30 0.0437 0.2055 0.5000 9.8 6ekb:A, 6ekc:B2, 6ekc:B3, 6ekc:B4, 6ekc:B5, 6ekc:B6, 6ekc:B7, 6ekc:B8, 6ekc:D1, 6ekc:D2, 6ekc:D3, 6ekc:D4, 6ekc:D5, 6ekc:D6, 6ekc:D7, 6ekc:D8, 6ekc:F1, 6ekc:F2, 6ekc:F3, 6ekc:F4, 6ekc:F5, 6ekc:F6, 6ekc:F7, 6ekc:F8, 6ekc:H1, 6ekc:H2, 6ekc:H3, 6ekc:H4, 6ekc:H5, 6ekc:H6, 6ekc:H7, 6ekc:H8, 6ekc:J1, 6ekc:J2, 6ekc:J3, 6ekc:J4, 6ekc:J5, 6ekc:J6, 6ekc:J7, 6ekc:J8, 6ekc:L1, 6ekc:L2, 6ekc:L3, 6ekc:L4, 6ekc:L5, 6ekc:L6, 6ekc:L7, 6ekc:L8, 6ekc:N1, 6ekc:N2, 6ekc:N3, 6ekc:N4, 6ekc:N5, 6ekc:N6, 6ekc:N7, 6ekc:N8, 6ekc:P1, 6ekc:P2, 6ekc:P3, 6ekc:P4, 6ekc:P5, 6ekc:P6, 6ekc:P7, 6ekc:P8, 6ekc:R1, 6ekc:R2, 6ekc:R3, 6ekc:R4, 6ekc:R5, 6ekc:R6, 6ekc:R7, 6ekc:R8, 6ekc:T1, 6ekc:T2, 6ekc:T3, 6ekc:T4, 6ekc:T5, 6ekc:T6, 6ekc:T7, 6ekc:T8

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218