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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SVPAIFLDRDGTINVDHGYVHEIDNFEFIDGVIDAMRELKKMGFALVVVTNQSGIARGKFTEAQFETLTEWMDWSLADRD
VDLDGIYYCPHHPQGSVEEFRQVCDCRKPHPGMLLSARDYLHIDMAASYMVGDKLEDMQAAVAANVGTKVLVRTGKPITP
EAENAADWVLNSLADLPQAIKKQQ

The query sequence (length=184) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3l8e:A 185 184 1.0000 0.9946 1.0000 1.50e-139 3esq:A, 3esr:A, 2gmw:A, 2gmw:B, 3l1u:A, 3l1u:B, 3l1v:A, 3l1v:B, 3l8e:B, 3l8f:A, 3l8g:A
2 3l8h:A 179 163 0.3098 0.3184 0.3497 1.05e-23 3l8h:B, 3l8h:C, 3l8h:D
3 2fps:B 163 150 0.2663 0.3006 0.3267 8.87e-20 2fpr:A, 2fpr:B, 2fps:A, 2fpu:A, 2fpu:B, 2fpw:A, 2fpw:B, 2fpx:A, 2fpx:B
4 3u7e:B 380 35 0.0815 0.0395 0.4286 0.10 3u7f:B, 3u7g:A, 3u7h:B, 3zvl:A, 3zvm:A, 3zvm:B, 3zvn:A
5 4u00:A 241 31 0.0761 0.0581 0.4516 0.24
6 7eap:A 755 64 0.1087 0.0265 0.3125 0.41 5yot:A, 5yot:B, 5yqs:A, 5yqs:B
7 6d0p:A 288 46 0.0815 0.0521 0.3261 0.56 6d0p:B, 6d0p:C, 6d0p:D
8 5gyn:A 295 36 0.0870 0.0542 0.4444 0.86 5aes:A, 5aes:B, 4bx0:A, 4bx2:A, 4bx2:B, 4bx3:A, 4bx3:B, 2cfr:A, 2cfs:A, 2cft:A, 9em1:A, 2oyc:A, 2p27:A, 2p69:A, 8qfw:A, 8qfw:B, 8s8a:A
9 5hrm:B 495 58 0.1141 0.0424 0.3621 1.2 5hrm:A, 5hrm:C, 5hrm:D
10 7ocn:A 690 76 0.1196 0.0319 0.2895 1.3 7ocn:B, 7ocp:A, 7ocp:B, 7ocq:A, 7ocq:B, 7ocr:A, 7ocr:B, 7ocs:A, 7ocs:B, 7ocs:C, 7ocs:D, 7oct:A, 7oct:B, 7ocu:A, 7ocu:B
11 4ggm:X 277 39 0.0707 0.0469 0.3333 2.0 4j6e:A
12 3bex:A 248 39 0.0870 0.0645 0.4103 2.0 3bex:B, 3bex:C, 3bex:D, 3bex:E, 3bex:F, 3bf1:A, 3bf1:F, 3bf1:B, 3bf1:C, 3bf1:E, 3bf1:D, 3bf3:A, 3bf3:B, 3bf3:C, 3bf3:D, 3bf3:E, 3bf3:F
13 3ahv:A 472 83 0.1304 0.0508 0.2892 2.2 3aht:A, 3aht:B, 3ahv:B, 7bzm:A, 7bzm:B, 3f4v:A, 3f4v:B, 3f5j:A, 3f5j:B, 3f5k:A, 3f5k:B, 3f5l:A, 3f5l:B, 4qlj:A, 4qlj:B, 4qlk:A, 4qlk:B, 4qll:A, 4qll:B, 2rgl:A, 2rgl:B, 2rgm:A, 2rgm:B, 3scn:A, 3scn:B, 3sco:A, 3sco:B, 3scp:A, 3scp:B, 3scq:A, 3scq:B, 3scr:A, 3scr:B, 3scs:A, 3scs:B, 3sct:A, 3sct:B, 3scu:A, 3scu:B, 3scv:A, 3scv:B, 3scw:A, 3scw:B
14 3fir:A 231 36 0.0652 0.0519 0.3333 2.9 3fir:B, 3fj7:A, 3fj7:B, 3fjm:A, 3fjm:B, 2hxw:A, 2hxw:B
15 4ygr:A 215 81 0.1087 0.0930 0.2469 2.9 4ygs:A
16 5jwz:A 724 74 0.1196 0.0304 0.2973 3.2 5jwz:B
17 7uuk:C 276 42 0.0761 0.0507 0.3333 3.5 7jm1:A, 7jm1:C, 7jm1:B, 7jm2:A, 7jm2:C, 7jm2:B, 7uuj:A, 7uuj:C, 7uuj:B, 7uuk:A, 7uuk:B, 7uul:A, 7uul:B, 7uul:D, 7uul:C, 7uul:F, 7uul:E, 7uum:A, 7uun:A, 7uuo:B
18 4jdp:B 265 80 0.1304 0.0906 0.3000 3.8 4jdp:A, 3qgm:A, 3qgm:B, 3qgm:C, 3qgm:D
19 6f5p:A 708 99 0.1250 0.0325 0.2323 4.4 5d98:A, 5d98:D, 6f5p:D, 6xzd:AP1, 6xzg:AP1, 6xzp:AP1, 6xzq:A, 6xzr:AP1, 6y0c:A
20 3gnn:A 266 73 0.1087 0.0752 0.2740 5.4
21 5tf0:A 733 33 0.0707 0.0177 0.3939 5.5 5tf0:B
22 3r09:A 197 54 0.1087 0.1015 0.3704 5.6 2ybd:A
23 3w81:A 616 66 0.1250 0.0373 0.3485 6.0 6i6r:A, 6i6r:B, 6i6x:A, 6i6x:B, 4kgj:B, 4kgj:A, 4kgl:B, 4kgl:A, 4kh2:B, 4kh2:A, 4obr:B, 4obr:A, 3w81:B, 3w82:A, 3w82:B
24 1og6:C 298 93 0.1250 0.0772 0.2473 6.1 1og6:A, 1og6:B
25 5n0k:A 1034 43 0.0761 0.0135 0.3256 7.2 5n4l:A, 5n4l:B
26 3l8a:B 385 137 0.1848 0.0883 0.2482 9.3 3l8a:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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