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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SVDDIKSLRLITAIKTPYLPDGRFDLEAYDALVNMQIVDGAEGVIVGGTTGEGQLMSWDEHIMLIGHTVNCFGGSIKVIG
NTGSNSTREAIHATEQGFAVGMHAALHINPYYGKTSLEGLVSHFESVLPMGPTVIYNVPSRTGQDIPPGVIHTVAQSANL
AGVKECVGNDRIKQYTDNRIVVWSGNDDQCHDAKWDYGATGVISVTSNLIPGLMRQLLFKGKNPSLNAKIMPLVNWLFEE
PNPIGLNTALAQLGVVRPVFRLPYVPLPLAKRVEFVNIVKEIGRENFVGEKDVKVLDDDDFILVGRY

The query sequence (length=307) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4hnn:F 320 307 1.0000 0.9594 1.0000 0.0 4hnn:A, 4hnn:B, 4hnn:C, 4hnn:D, 4hnn:E, 4hnn:G, 4hnn:H
2 6vvh:BBB 313 307 0.7948 0.7796 0.7948 0.0 4dpq:A, 4dpq:B, 7mds:A, 7mds:B, 6vvh:AAA, 6vvh:CCC, 6vvh:DDD
3 5ui3:C 306 306 0.6319 0.6340 0.6340 2.50e-142 5ui3:D, 5ui3:A, 5ui3:B
4 4dxv:A 291 288 0.3322 0.3505 0.3542 1.52e-46 3pue:B, 3pul:B, 3rk8:A, 3rk8:B, 3tak:A, 3tak:B, 3tce:A, 3tce:B, 3tdf:A, 3tdf:B, 3u8g:A, 3u8g:B
5 5t25:A 293 286 0.3192 0.3345 0.3427 5.44e-44 2ats:A, 2ats:B, 3i7s:A, 3i7s:B, 7jz8:A, 7jz8:B, 7jza:A, 7jza:B, 7jzb:A, 7jzb:B, 7jzg:A, 7jzg:B, 5t25:B, 1yxd:A, 1yxd:B
6 1o5k:A 295 289 0.3420 0.3559 0.3633 2.56e-43
7 5ktl:A 295 266 0.2899 0.3017 0.3346 6.39e-42 5ktl:B
8 4pfm:A 295 270 0.3062 0.3186 0.3481 3.01e-41 4pfm:B
9 3puo:A 292 265 0.2899 0.3048 0.3358 5.09e-40 3puo:B, 3s8h:A, 3s8h:B
10 4fha:A 307 284 0.2801 0.2801 0.3028 1.26e-37 4fha:B
11 3di1:B 291 267 0.2801 0.2955 0.3221 1.04e-36 3di1:A
12 7kkd:B 306 269 0.2866 0.2876 0.3271 6.17e-32 5f1u:A, 5f1u:B, 5f1u:C, 5f1u:D, 5f1v:A, 5f1v:C, 5f1v:B, 5f1v:D, 7kg2:A, 7kg2:C, 7kg2:B, 7kg2:D, 7kg2:E, 7kg2:F, 7kg5:A, 7kg5:B, 7kg5:C, 7kg5:E, 7kg5:F, 7kg9:A, 7kg9:E, 7kg9:B, 7kg9:C, 7kg9:D, 7kg9:F, 7kh4:A, 7kh4:F, 7kh4:B, 7kh4:C, 7kh4:D, 7kh4:E, 7kk1:A, 7kk1:B, 7kk1:C, 7kk1:D, 7kk1:E, 7kk1:F, 7kkd:A, 7kkd:F, 7kkd:E, 7kkd:C, 7kkd:D, 7kkg:A, 7kkg:D, 7kkg:B, 7kkg:E, 7kkg:C, 7kkg:F, 7kkt:A, 7kkt:F, 7kkt:B, 7kkt:E, 7kkt:C, 7kkt:D, 7kls:A, 7kls:F, 7kls:B, 7kls:C, 7kls:D, 7kls:E, 7klt:A, 7klt:C, 7klt:E, 7klt:F, 7kly:A, 7kly:D, 7kly:B, 7kly:C, 7kly:E, 7kly:F, 7km0:B, 7km0:C, 7km0:A, 7km0:D, 7km0:E, 7km0:F, 7km1:A, 7km1:B, 7km1:C, 7km1:D, 7km1:E, 7km1:F, 7kn9:A, 7kn9:B, 7kn9:C, 7kn9:D, 7kn9:E, 7kn9:F, 7knz:B, 7knz:C, 7knz:A, 7knz:D, 7knz:E, 7knz:F, 7ko3:A, 7ko3:B, 7ko3:C, 7ko3:D, 7ko3:E, 7ko3:F, 7kpc:A, 7kpc:B, 7kpc:C, 7kpc:D, 7kpc:E, 7kpc:F, 7kpe:B, 7kpe:C, 7kpe:A, 7kpe:D, 7kpe:E, 7kpe:F, 7kr7:A, 7kr7:E, 7kr7:B, 7kr7:C, 7kr7:D, 7kr7:F, 7kr8:B, 7kr8:D, 7kto:A, 7kto:B, 7kto:C, 7kto:D, 7kto:E, 7kto:F, 7ku6:D, 7kuz:A, 7kuz:F, 7kuz:B, 7kuz:C, 7kuz:D, 7kuz:E, 7kwf:B, 7kwf:F, 7kwf:A, 7kwf:C, 7kwf:D, 7kwf:E, 7kwn:B, 7kwp:A, 7kwp:B, 7kwp:C, 7kwp:D, 7kwp:E, 7kwp:F, 7kx1:A, 7kxg:A, 7kxg:C, 7kxg:B, 7kxg:D, 7kxg:E, 7kxg:F, 7kxh:A, 7kxh:D, 7kxh:B, 7kxh:C, 7kxh:E, 7kxh:F, 7kz2:A, 7kz2:D, 7kz2:B, 7kz2:C, 7kz2:E, 7kz2:F, 7lcf:A, 7lcf:B, 7lcf:F, 7lcf:C, 7lcf:D, 7lcf:I, 7lcf:E, 7lcf:G, 7lcf:H, 7lcf:J, 7lcf:K, 7lcf:L, 7m06:B, 7m06:C, 7m06:D, 4m19:A, 4m19:B, 4m19:C, 4m19:D, 4mlr:A, 4mlr:D, 4mlr:C, 4mlr:E, 4mlr:F, 4mlr:G, 4mlr:H, 6u01:B
13 5ud6:C 299 272 0.2866 0.2943 0.3235 9.23e-31 5ud6:A, 5ud6:B, 5ud6:D
14 4i7w:A 294 257 0.2638 0.2755 0.3152 3.15e-30 4i7w:B
15 7lvl:A 296 282 0.2866 0.2973 0.3121 5.34e-30 7lvl:B, 7lvl:C, 7lvl:E, 7lvl:D, 7lvl:F, 7mjf:A, 7mjf:B, 7mjf:C, 7mjf:D, 7mjf:E, 7mjf:F
16 5j5d:A 297 242 0.2443 0.2525 0.3099 3.25e-27 3l21:B, 1xxx:A, 1xxx:B, 1xxx:C, 1xxx:D, 1xxx:E, 1xxx:F, 1xxx:G, 1xxx:H
17 3nev:A 298 219 0.2020 0.2081 0.2831 7.07e-18 3nev:B, 3nev:C, 3nev:D, 4oe7:A, 4oe7:B, 4oe7:C, 4oe7:D, 4onv:A, 4onv:B, 4onv:C, 4onv:D, 4ptn:A, 4ptn:B, 4ptn:C, 4ptn:D, 4u4m:A, 4u4m:B, 4u4m:C, 4u4m:D
18 2wpb:A 302 292 0.2248 0.2285 0.2363 3.22e-14 4bwl:A, 4bwl:B, 4bwl:C, 4bwl:D, 1fdy:A, 1fdy:B, 1fdy:C, 1fdy:D, 1fdz:A, 1fdz:B, 1fdz:C, 1fdz:D, 1hl2:A, 1hl2:B, 1hl2:C, 1hl2:D, 3lbc:D, 3lcw:A, 3lcw:B, 3lcw:C, 3lcw:D, 4uui:A, 4uui:B, 4uui:C, 4uui:D, 2wkj:C, 2wkj:D, 2wpb:B, 2wpb:C, 2wpb:D, 2xfw:A, 2xfw:B, 2xfw:C, 2xfw:D
19 5c55:A 307 301 0.2248 0.2248 0.2292 6.95e-14 5c55:B
20 8u8w:A 297 292 0.2248 0.2323 0.2363 7.50e-14
21 3na8:A 291 264 0.2117 0.2234 0.2462 2.97e-11 3na8:B, 3na8:C, 3na8:D
22 4woq:C 290 192 0.1498 0.1586 0.2396 7.33e-10 4woq:D, 4woq:E, 4woq:F, 4woq:H, 4woz:B, 4woz:F
23 2nuy:A 288 187 0.1401 0.1493 0.2299 5.07e-09 2nuy:B
24 6rb7:A 305 215 0.1531 0.1541 0.2186 1.43e-08 6rb7:B, 6rb7:E, 6rb7:F, 6rd1:A, 6rd1:B
25 4img:A 293 222 0.1661 0.1741 0.2297 1.89e-08 4imf:A, 4imf:B, 4img:B
26 6g3z:A 293 211 0.1792 0.1877 0.2607 3.54e-08 6g3z:B, 6gt8:A, 6gt8:B, 6gv2:A, 6gv2:B, 6h2s:A, 6h2s:B, 6h2s:C, 6h2s:D, 6h7s:A, 6h7s:B, 1w3i:A, 1w3i:B, 1w3i:C, 1w3i:D, 1w3n:A, 1w3n:B, 1w3n:C, 1w3n:D, 1w3t:A, 1w3t:B, 1w3t:C, 1w3t:D
27 1f74:A 293 183 0.1368 0.1433 0.2295 6.30e-08 1f73:A, 1f73:B, 1f73:C, 1f73:D, 1f74:C, 1f7b:A, 1f7b:C
28 3qfe:A 305 208 0.1596 0.1607 0.2356 1.95e-07
29 2r94:A 286 196 0.1498 0.1608 0.2347 1.62e-06 2r94:D, 2r94:B, 2r94:C
30 8do5:B 324 146 0.1205 0.1142 0.2534 2.50e-06 8do5:A
31 2hmc:A 314 215 0.1824 0.1783 0.2605 3.30e-04
32 5kzd:A 284 207 0.1336 0.1444 0.1981 0.002 5kzd:B, 5kzd:C, 5kzd:D
33 3zwm:H 253 64 0.0717 0.0870 0.3438 0.035 3i9j:A, 3i9j:B, 3i9k:B, 3i9l:A, 3i9o:A, 3i9o:B, 1r15:A, 1r15:B, 1r15:C, 1r15:D, 1r15:E, 1r15:F, 1r15:G, 1r15:H, 1r16:A, 1r16:B, 3zwm:A, 3zwm:B, 3zwm:C, 3zwm:D, 3zwm:E, 3zwm:F, 3zwm:G, 3zwn:A, 3zwn:B, 3zwo:A, 3zwo:B, 3zwo:C, 3zwo:E, 3zwo:F, 3zwo:G, 3zwo:H, 3zwp:A, 3zwp:B, 3zwp:C, 3zwp:D, 3zwp:E, 3zwp:F, 3zwp:G, 3zwp:H, 3zwv:A, 3zwv:H, 3zwv:B, 3zwv:C, 3zwv:D, 3zwv:E, 3zwv:F, 3zwv:G, 3zww:A, 3zww:B, 3zww:C, 3zww:D, 3zww:E, 3zww:F, 3zww:G, 3zww:H, 3zwx:A, 3zwx:B, 3zwx:C, 3zwx:D, 3zwx:E, 3zwx:F, 3zwx:G, 3zwx:H, 3zwy:A, 3zwy:B, 3zwy:C, 3zwy:D, 3zwy:E, 3zwy:F, 3zwy:G, 3zwy:H
34 2fli:C 219 143 0.1303 0.1826 0.2797 0.14 2fli:A, 2fli:B, 2fli:D, 2fli:E, 2fli:F, 2fli:G, 2fli:H, 2fli:I, 2fli:J, 2fli:K, 2fli:L
35 5a22:A 2002 49 0.0554 0.0085 0.3469 2.3
36 6u1x:A 2059 49 0.0554 0.0083 0.3469 2.3
37 5yyl:B 375 52 0.0456 0.0373 0.2692 2.6
38 6et3:B 275 61 0.0717 0.0800 0.3607 2.8
39 6l0a:C 365 50 0.0391 0.0329 0.2400 3.6 7ca0:A, 7ca0:B, 7ca0:C, 7ca0:D, 7ca1:A, 7ca1:C, 7ca1:B, 7ca1:D, 6l0a:A, 6l0a:B, 6l0a:D, 6l0b:A, 6l0b:C, 6l0b:B, 6l0b:D, 6l0f:A, 6l0f:B, 6l0f:C, 6l0f:D, 6l0g:A, 6l0g:B, 6l0g:C, 6l0g:D, 6l0h:A, 6l0h:B, 6l0h:C, 6l0h:D, 6l0i:A, 6l0i:B, 6l0i:C, 6l0i:D, 6l0j:A, 6l0j:D, 6l0j:B, 6l0j:C, 6l0k:A, 6l0k:B, 6l0k:C, 6l0k:D
40 7asd:AA 413 52 0.0456 0.0339 0.2692 3.8 7asd:BA, 7asd:CA, 7asd:DA, 7asd:EA, 7asd:FA, 7asd:GA, 7asd:HA, 5yyl:A
41 2cdu:A 451 64 0.0684 0.0466 0.3281 5.7 2cdu:B
42 7ptr:A 725 31 0.0423 0.0179 0.4194 5.8 7ptr:B, 7ptr:C, 7ptr:D, 7ptr:E, 7ptr:F, 7ptu:A, 7ptu:B, 7ptu:C, 7ptu:D, 7ptu:E
43 7bka:E 171 39 0.0456 0.0819 0.3590 9.5 4b0b:A, 4b0b:B, 4b0c:A, 4b0c:B, 4b0c:D, 4b0c:C, 4b0c:E, 4b0i:A, 4b0i:B, 4b0i:C, 4b0i:D, 4b0i:E, 4b0j:A, 4b0j:B, 4b0j:C, 4b0j:D, 4b0j:E, 4b0j:F, 4b0j:G, 4b0j:H, 4b0j:I, 4b0j:J, 4b0j:K, 4b0j:L, 4b0j:M, 4b0j:N, 4b0j:O, 4b0j:P, 4b0j:Q, 4b0j:R, 4b0j:S, 4b0j:T, 8b72:A, 8b72:B, 4b8u:A, 4b8u:B, 7bhj:B, 7bhj:C, 7bhj:D, 7bhj:E, 7bis:A, 7bis:B, 7bis:C, 7bis:D, 7bis:E, 7bk9:A, 7bk9:B, 7bk9:C, 7bk9:D, 7bk9:E, 7bka:A, 7bka:B, 7bka:C, 7bka:D, 4cl6:A, 4cl6:B, 4cl6:C, 4cl6:D, 4cl6:E

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218