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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
STRVRYAPSPTGLQHIGGIRTALFNYFFAKSCGGKFLLRIEDTDQSRYSPEAENDLYSSLKWLGISFDEGPVVGGDYAPY
VQSQRSAIYKQYAKYLIESGHAYYCYCSPERLERIKKIQNINKMPPGYDRHCRNLSNEEVENALIKKIKPVVRFKIPLEG
DTSFDDILLGRITWANKDISPDPVILKSDGLPTYHLANVVDDYLMKITHVLRAQEWVSSGPLHVLLYKAFKWKPPIYCHL
PMVMGNDGQKLSKRHGSTALRQFIEDGYLPEAIINYVTLLGWSYDDKREFFSKNDLEQFFSIEKINKSPAIFDYHKLDFF
NSYYIREKKDEDLFNLLLPFFQKKGYVSKPSTLEENQKLKLLIPLIKSRIKKLSDALNMTKFFYEDIKSWNLDEFLSRKK
TAKEVCSILELIKPILEGFEKRSSEENDKIFYDFAESNLGEILLPIRIAALGSKVSPPLFDSLKLIGKSKVFERIKLAQE
FLRIN

The query sequence (length=485) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4gri:B 485 485 1.0000 1.0000 1.0000 0.0 4gri:A
2 2cuz:A 468 479 0.3856 0.3996 0.3904 3.68e-114 2cv0:A, 2cv0:B, 2cv1:A, 2cv1:B, 2cv2:A, 2cv2:B, 2dxi:A, 2dxi:B, 1g59:A, 1g59:C, 1j09:A, 1n75:A, 1n77:A, 1n77:B, 1n78:A, 1n78:B
3 8vc5:A 488 487 0.3649 0.3627 0.3634 2.54e-105 8vc5:B
4 8i9i:A 468 488 0.3546 0.3675 0.3525 8.06e-102 8i9i:B
5 6brl:A 502 510 0.3753 0.3625 0.3569 6.85e-99
6 3al0:C 564 489 0.3588 0.3085 0.3558 3.04e-96 3afh:A, 3akz:B, 3akz:D, 3akz:C, 3akz:A
7 2cfo:A 484 392 0.3175 0.3182 0.3929 8.74e-93
8 4g6z:A 380 383 0.2784 0.3553 0.3525 5.80e-81
9 4a91:A 290 250 0.1814 0.3034 0.3520 1.77e-36 1nzj:A
10 3aii:A 455 296 0.1897 0.2022 0.3108 3.33e-29
11 4h3s:A 585 229 0.1237 0.1026 0.2620 3.66e-12
12 8uk6:A 573 311 0.1546 0.1309 0.2412 2.12e-08
13 4jyz:A 542 220 0.1113 0.0996 0.2455 1.35e-07 1euq:A, 1euy:A, 1exd:A, 1gtr:A, 1gts:A, 4jxx:A, 4jxz:A, 1o0b:A, 1o0c:A, 1qrs:A, 1qrt:A, 1qru:A, 1qtq:A, 2rd2:A, 2re8:A, 1zjw:A
14 5zdk:A 543 241 0.1320 0.1179 0.2656 7.38e-07 5zdl:A
15 7wao:A 502 220 0.1113 0.1076 0.2455 1.11e-06 7waj:A, 7wak:A, 7wal:A
16 1irx:B 508 151 0.0722 0.0689 0.2318 0.66 1irx:A
17 8rv0:Y 495 161 0.0784 0.0768 0.2360 2.2 8rvm:YYY, 8rxu:AAA, 8rxu:MMM, 8rxu:YYY
18 7y3h:A 396 133 0.0660 0.0808 0.2406 4.2 8gx4:A, 8gzi:A
19 6wq6:A 547 246 0.1031 0.0914 0.2033 4.4 6wqi:A, 6wqi:B, 6wqs:A, 6wqt:A
20 2cyb:A 319 26 0.0206 0.0313 0.3846 4.8 2cyb:B
21 1yw1:A 393 76 0.0557 0.0687 0.3553 6.3
22 6asl:A 430 76 0.0557 0.0628 0.3553 7.1
23 7ktr:A 3042 52 0.0351 0.0056 0.3269 7.2
24 8xvg:L 3485 52 0.0351 0.0049 0.3269 9.1 8xvv:L

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218