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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
STQYWEEEIEIMSREKLQELQLQRLKKTINIAANSPYYKEVFSKNGITGDSIQSLDDIRKIPFTTKSDMRANYPFGLVAG
DMKRDGVRIHSSNPTVIVHSQHDLDSWANLVARCLYMVGIRKTDVFQNSSGYGMFTGGLGFQYGAERLGCLTVPAAAGNS
KRQIKFISDFKTTALHAIPSYAIRLAEVFQEEGIDPRETTLKTLVIGAEPHTDEQRRKIERMLNVKAYNSFGMTEMNGPG
VAFECQEQNGMHFWEDCYLVEIIDPETGEPVPEGEIGELVLTTLDREMMPLIRYRTRDLTRILPGKCPCGRTHLRIDRIK
GRSDDMFIIKGVNIFPMQVEKILVQFPELGSNYLITLETNQDEMIVEVELSDLSTDNYIELEKIRRDIIRQLKDEILVTP
KVKLVKKGSLPQSEGKAVRVKDLRDN

The query sequence (length=426) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4r1m:A 435 433 1.0000 0.9793 0.9838 0.0 4r1l:A, 4r1l:B, 4r1l:C, 4r1l:D, 4r1m:B, 4r1m:C, 4r1m:D, 4rvn:A, 4rvn:B, 4rvn:C, 4rvn:D, 4rvo:A, 4rvo:B, 4rvo:C, 4rvo:D
2 2y4o:A 433 430 0.4319 0.4249 0.4279 7.60e-119 2y4o:B
3 2y27:B 427 427 0.4178 0.4169 0.4169 5.03e-114 2y27:A, 2y4n:A, 2y4n:B
4 6he0:A 477 446 0.3333 0.2977 0.3184 4.16e-59 6hdw:A, 6hdx:A, 6hdy:A, 6he2:A, 6he2:B
5 6six:B 437 369 0.2254 0.2197 0.2602 4.00e-26 6siw:A, 6siw:B, 6six:A, 6siy:A, 6siy:B, 6siz:A, 6siz:B, 6tm4:AAA, 6tm4:BBB, 6wuq:A, 6wuq:B
6 3pbk:A 555 108 0.0798 0.0613 0.3148 5.72e-06 3pbk:B
7 4wv3:B 518 278 0.1643 0.1351 0.2518 8.43e-06 4wv3:A
8 8wev:A 486 170 0.1221 0.1070 0.3059 1.71e-04 8wev:B
9 7kdn:A 622 334 0.1667 0.1141 0.2126 0.002 7kdn:B, 7kdn:C, 7kdn:D, 7kdn:E, 7kdn:F
10 4rlf:B 519 277 0.1573 0.1291 0.2419 0.003 6m2t:A, 6m2t:B, 6m2t:C, 6m2t:D, 6m2u:A, 6m2u:B, 4rlf:A, 4rlq:A, 4rlq:B, 4rm2:A, 4rm2:B, 4rm3:A, 4rm3:B, 4rmn:A, 4rmn:B, 4zjz:A, 4zjz:B
11 7a9j:A 503 173 0.0915 0.0775 0.2254 0.054 7a9i:A
12 8w0b:A 667 357 0.1784 0.1139 0.2129 0.076 7kds:A, 8v4o:A, 8v4o:B, 8v4o:C, 8v4p:A, 8v4p:B, 8v4p:C, 8v4r:A, 8v4r:B, 8v4r:C, 8w0b:B, 8w0b:C, 8w0c:A, 8w0c:B, 8w0c:C, 8w0d:A, 8w0d:B, 8w0d:C, 8w0h:A, 8w0h:B, 8w0h:C, 8w0j:A, 8w0j:B, 8w0j:C, 8w0l:A, 8w0l:B, 8w0l:C, 8w0m:A, 8w0m:B, 8w0m:C
13 7l4g:B 668 255 0.1549 0.0988 0.2588 0.13 9c8s:A, 9c8s:B, 9c8s:C, 8eps:A, 8eps:B, 8eps:C, 8g0r:A, 8g0r:B, 8g0r:C, 8g0s:A, 8g0s:B, 8g0s:C, 8g0t:A, 8g0t:B, 8g0t:C, 8g0u:A, 8g0u:B, 8g0v:A, 8g0v:B, 8g0v:C, 5ifi:A, 5ifi:B, 5ifi:C, 5k85:A, 5k85:B, 5k85:C, 5k8f:A, 5k8f:B, 5k8f:C, 7kno:A, 7kno:B, 7kno:C, 7knp:A, 7knp:B, 7knp:C, 7l4g:A, 7l4g:C, 5u29:A, 5u29:B, 5u29:C, 8v5g:A, 8v5g:B
14 7thq:B 505 299 0.1573 0.1327 0.2241 0.14 6o6e:B, 7thq:A
15 5bsm:A 530 276 0.1408 0.1132 0.2174 0.14 5bsm:B, 5bsr:A, 5bst:A, 5bsu:A, 5bsv:A, 5bsw:A, 5bsw:B, 5u95:D, 5u95:B, 5u95:C
16 4gxq:A 506 190 0.1033 0.0870 0.2316 0.22 4fut:A, 4gxq:B, 4gxq:C, 4gxr:A
17 3rg2:C 613 170 0.0962 0.0669 0.2412 0.39 6iyk:A, 6iyk:B, 6iyl:A, 6iyl:B, 4iz6:A, 4iz6:B, 8k5s:A, 8k5s:B, 8k5t:A, 8k5t:B, 3rg2:A, 3rg2:B, 3rg2:H, 3rg2:D, 3rg2:E, 3rg2:F, 3rg2:I, 3rg2:G, 3rg2:J
18 4ir7:A 508 24 0.0329 0.0276 0.5833 0.51
19 7kvy:A 633 318 0.1479 0.0995 0.1981 0.64 7kcp:A, 7kq6:A, 7kq6:B, 7kq6:C, 7kqz:A, 7l3p:A, 7l3q:A, 7l3q:B, 7l3q:C
20 5ja2:A 1238 215 0.1056 0.0363 0.2093 0.84 5ja1:A, 5t3d:A
21 3a9v:A 528 147 0.0822 0.0663 0.2381 1.8 3ni2:A
22 6e97:B 537 227 0.1127 0.0894 0.2115 1.8 6e8o:A, 6e8o:B, 6e97:A
23 8a22:Be 228 61 0.0423 0.0789 0.2951 1.9 8apn:Be, 8apo:Be
24 3r44:A 502 39 0.0305 0.0259 0.3333 1.9 5zrn:A, 5zrn:B
25 1wsv:A 371 85 0.0540 0.0620 0.2706 2.1 1wsv:B
26 8et7:A 532 28 0.0305 0.0244 0.4643 2.1 8et8:A
27 3e7w:A 508 71 0.0516 0.0433 0.3099 2.6 3e7x:A
28 8rwj:D 676 74 0.0516 0.0325 0.2973 3.2 8rwj:I, 8rwj:A, 8rwj:B, 8rwj:C, 8rwj:E, 8rwj:F, 8rwj:G, 8rwj:H, 1ry2:A
29 4v8l:D 2822 44 0.0469 0.0071 0.4545 3.4 4ce4:o, 6hiv:US, 6hiv:UT, 6hiw:US, 6hiw:UT, 6hiy:US, 6hiy:UT, 4v8l:E, 4v8l:F, 4v8l:A, 4v8l:B, 4v8l:C, 4v8v:A, 4v8v:B, 4v8v:C, 4v8v:D, 4v8v:E, 4v8v:F, 4v8w:D, 4v8w:E, 4v8w:F, 4v8w:A, 4v8w:B, 4v8w:C
30 7tmm:A 593 50 0.0352 0.0253 0.3000 3.9 7tmo:A, 7tmo:E, 7tmp:A, 7tmq:A, 7tmr:E, 7tms:E, 7tmt:E
31 8yyr:A 496 261 0.1408 0.1210 0.2299 4.1 7dq5:A, 7dq5:B, 7dq6:A, 7dq6:B, 6m01:A, 8yyq:A
32 3fcc:A 500 115 0.0845 0.0720 0.3130 4.4 3dhv:A, 3fce:A
33 8cdb:A 306 88 0.0563 0.0784 0.2727 5.6 8cd8:A, 8cd8:C, 8cdb:B, 8cdb:C, 8cdb:D, 8cdb:E, 8cdb:F, 8cdb:G, 8cdb:H, 8cdb:I, 8cdb:J, 8cdb:K, 8cdb:L, 8cdb:M, 8cdb:N, 2cki:A, 2cki:B, 2j83:A, 2j83:B, 3lum:A, 3lum:B, 3lum:C, 3lum:D, 3lun:A, 3lun:B
34 8djk:B 281 88 0.0610 0.0925 0.2955 6.2 8djm:B
35 5x8f:B 485 29 0.0258 0.0227 0.3793 7.2 5buq:B, 5bur:A, 5bur:B, 5bus:A, 5bus:B, 5gtd:A, 5gtd:B, 5x8f:A, 5x8f:C, 5x8f:D, 5x8g:A, 5x8g:B, 5x8g:D, 5x8g:C
36 5wm3:A 537 244 0.1338 0.1061 0.2336 8.3 5wm2:A, 5wm4:A, 5wm5:A, 5wm6:A, 5wm7:A
37 8him:B 971 62 0.0376 0.0165 0.2581 8.4
38 1o9j:A 494 59 0.0399 0.0344 0.2881 9.3 1o9j:B, 1o9j:C, 1o9j:D
39 5zr2:C 198 44 0.0282 0.0606 0.2727 9.6 6m1x:C, 6m1x:D, 5zr2:A, 5zr2:B, 5zr2:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218