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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
STPLQGIKVLDFTGVQSGPSCTQMLAWFGADVIKIERPGVGDVTRHQLRDIPDIDALYFTMLNSNKRSIELNTKTAEGKE
VMEKLIREADILVENFHPGAIDHMGFTWEHIQEINPRLIFGSIKGFDECSPYVNVKAYENVAQAAGGAASTTGFWDGPPL
VSAAALGDSNTGMHLLIGLLAALLHREKTGRGQRVTMSMQDAVLNLCRVKLRDQQRLDKLGYLEEYPQYPNGTFGDAVPR
GGNAGGGGQPGWILKCKGWETDPNAYIYFTIQEQNWENTCKAIGKPEWITDPAYSTAHARQPHIFDIFAEIEKYTVTIDK
HEAVAYLTQFDIPCAPVLSMKEISLDPSLRQSGSVVEVEQPLRGKYLTVGCPMKFSAFTPDIKAAPLLGEHTAAVLQELG
YSDDEIAAMKQNHAI

The query sequence (length=415) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1q6y:A 417 415 1.0000 0.9952 1.0000 0.0 1pt5:A, 1pt5:B, 1pt8:A, 1pt8:B, 1q7e:A
2 3ubm:B 430 423 0.7084 0.6837 0.6950 0.0 3ubm:A, 3ubm:C, 3ubm:D
3 1p5r:A 427 426 0.6145 0.5972 0.5986 1.86e-176 1p5r:B, 1t3z:A, 1t3z:B, 1t4c:A, 1t4c:B, 1vgq:A, 1vgq:B, 1vgr:A, 1vgr:B, 2vjk:A, 2vjk:B, 2vjl:A, 2vjl:B, 2vjm:A, 2vjm:B, 2vjo:A, 2vjo:B
4 9br7:C 403 415 0.3060 0.3151 0.3060 8.99e-53 9br7:A, 9br7:D
5 5yx6:A 360 399 0.2482 0.2861 0.2581 6.54e-28
6 2yim:A 355 200 0.1518 0.1775 0.3150 2.39e-24 2gce:A, 2gce:B, 2gce:C, 2gce:D, 2gci:A, 2gci:B, 2gci:C, 2gci:D, 2gd0:A, 2gd0:B, 2gd0:C, 2gd0:D, 2gd2:A, 2gd2:B, 2gd2:C, 2gd2:D, 2gd6:A, 2gd6:B, 2gd6:C, 2gd6:D, 2yim:B, 2yim:C, 2yim:D
7 1xvt:A 402 419 0.2506 0.2587 0.2482 1.04e-19 1xa4:B, 1xvu:A, 1xvv:A
8 8apq:A 406 434 0.2651 0.2709 0.2535 1.03e-17 8apq:B, 8apq:C, 8apq:D, 8apq:E, 8apq:F
9 2eul:A 156 55 0.0554 0.1474 0.4182 0.53 2eul:D
10 7kn1:A 336 56 0.0434 0.0536 0.3214 2.0 7kn1:B
11 7a09:O 296 68 0.0530 0.0743 0.3235 2.3 6fec:P, 5k0y:P, 1kl9:A, 8oz0:D, 8p03:A, 8p09:A, 8pj1:r, 8pj2:r, 8pj3:r, 8pj4:r, 8ppl:Ir, 7qp6:r, 7qp7:r, 7syr:j, 7sys:j, 6yal:A, 6yam:A, 6yan:A, 6ybv:r, 6zmw:r, 6zp4:O
12 3nt6:A 565 48 0.0410 0.0301 0.3542 3.2 3nt6:B, 3nta:A, 3nta:B, 3ntd:A, 3ntd:B, 4ocg:A, 4ocg:B
13 1ta9:B 394 69 0.0554 0.0584 0.3333 5.8 1ta9:A
14 2yjg:A 418 88 0.0627 0.0622 0.2955 6.2 2yjg:B
15 4nmc:A 941 52 0.0458 0.0202 0.3654 7.3
16 6tv9:A 372 53 0.0434 0.0484 0.3396 7.6 6tv9:B, 6tv9:C, 6tv9:D, 6tv9:E, 6tv9:F, 6tv9:G, 6tv9:H
17 7na0:A 981 52 0.0458 0.0194 0.3654 8.2 7na0:B, 4nm9:A, 4nm9:B, 4nma:A, 4nma:B, 4nmb:A, 4nmb:B, 4nmc:B, 4nmd:A, 4nmd:B, 4nme:A, 4nme:B, 4nmf:A, 4nmf:B
18 3sjd:C 292 71 0.0458 0.0651 0.2676 9.9 3sjd:A, 3sjd:B, 2woj:C, 3zs8:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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