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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SSLDEPERQVVMWESVGDEKDQVFKQLYRQVFGNAYLMESDLEELLVPESQLLMGSISVKDFIKRVAKSDAYKKRFFEPC
GPYRFVELCTKHFLGRGPRDQKEVSEHVQRLANEGYDADVDSYMDSEEYMSLFGENGVPRFVFKGTYEGNDQFNRLAAMR
QFADGSYTDTRSGSTAPRKAQKAELTMAEGDFVGRAKVSRGLPAETSAAKTGTPPVRALKGPVNPRAGVRVRIKVVDNLY
QVYEIPPMADPKAKVNAFWAKPIPS

The query sequence (length=265) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7ezx:MC 280 265 1.0000 0.9464 1.0000 0.0 7ezx:ME, 7y4l:ZG, 7y4l:MG, 7y5e:ZI, 7y5e:MI, 7y7a:MJ, 7y7a:Mk, 7y7a:ZJ, 7y7a:Zk
2 7ezx:d4 297 204 0.3321 0.2963 0.4314 8.86e-49 7ezx:dD, 6kgx:d9, 6kgx:dJ, 7y4l:d5, 7y4l:dJ, 7y5e:dD, 7y5e:dQ, 7y7a:d2, 7y7a:dc, 7y7a:dF, 7y7a:dM
3 7y4l:bH 407 156 0.2830 0.1843 0.4808 1.30e-46 7ezx:bB, 7ezx:bM, 6kgx:b8, 6kgx:bA, 7y4l:b4, 7y5e:bJ, 7y5e:bM, 7y7a:b3, 7y7a:bC, 7y7a:bV, 7y7a:bp
4 5y6p:dy 303 142 0.2642 0.2310 0.4930 1.89e-46 5y6p:dz
5 7y4l:z8 463 136 0.2642 0.1512 0.5147 7.10e-43 7ezx:zJ, 7ezx:zL, 6kgx:zE, 6kgx:zG, 7y4l:zF, 7y5e:zK, 7y5e:zF, 7y7a:zT, 7y7a:zQ, 7y7a:zb, 7y7a:z6
6 5y6p:B2 374 142 0.2566 0.1818 0.4789 3.08e-41 5y6p:b3
7 7ezx:O3 375 134 0.2415 0.1707 0.4776 7.74e-39 7ezx:OO, 6kgx:b1, 6kgx:o1, 6kgx:b4, 6kgx:o4, 7liz:A, 7y4l:Y7, 7y4l:b7, 7y5e:YP, 7y5e:bP, 7y7a:YL, 7y7a:bL, 7y7a:bU, 7y7a:YU
8 5y6p:a8 362 141 0.2302 0.1685 0.4326 2.60e-34 5y6p:a9
9 7ezx:e2 248 235 0.3132 0.3347 0.3532 6.94e-34 7ezx:eR, 6kgx:e3, 6kgx:eD, 7y4l:eK, 7y4l:e1, 7y5e:eA, 7y5e:e7, 7y7a:eD, 7y7a:e5, 7y7a:eg, 7y7a:ei
10 5y6p:ex 233 186 0.2528 0.2876 0.3602 1.26e-30 5y6p:ew, 5y6p:fz, 5y6p:fd
11 8tpj:A 210 115 0.1698 0.2143 0.3913 2.42e-20
12 7ezx:X1 324 123 0.1660 0.1358 0.3577 2.03e-19 7ezx:X7, 7ezx:X9, 7ezx:XF, 7ezx:XI, 7ezx:XK, 6kgx:X2, 6kgx:X6, 6kgx:X7, 6kgx:XB, 6kgx:XF, 6kgx:XI, 7y4l:XB, 7y4l:XC, 7y4l:XD, 7y4l:XE, 7y4l:X2, 7y4l:X6, 7y5e:XE, 7y5e:XG, 7y5e:XH, 7y5e:XO, 7y5e:X1, 7y5e:X4, 7y7a:X1, 7y7a:X4, 7y7a:X8, 7y7a:XI, 7y7a:XK, 7y7a:XP, 7y7a:XR, 7y7a:XS, 7y7a:Xe, 7y7a:Xj, 7y7a:Xl, 7y7a:Xn
13 5y6p:24 331 117 0.1623 0.1299 0.3675 2.19e-19 5y6p:X5, 5y6p:S8, 5y6p:X9, 5y6p:aX, 5y6p:bX
14 5y6p:aW 228 121 0.1698 0.1974 0.3719 6.43e-19 5y6p:14, 5y6p:W5, 5y6p:R8, 5y6p:W9, 5y6p:bW
15 8uhe:K 593 126 0.1811 0.0809 0.3810 5.07e-17
16 8uhe:K 593 125 0.1472 0.0658 0.3120 1.77e-13
17 6yet:A 104 56 0.0679 0.1731 0.3214 0.40
18 4l9m:A 522 39 0.0604 0.0307 0.4103 0.44
19 8oxm:A 2748 65 0.0679 0.0066 0.2769 8.0 8oxm:B
20 7sic:A 2773 65 0.0679 0.0065 0.2769 8.0 8oxo:A, 8oxo:B, 8oxp:A, 8oxp:B, 7sic:B, 7sid:A, 7sid:C
21 7ni5:A 2791 65 0.0679 0.0064 0.2769 8.0 7ni4:A, 7ni4:B, 7ni5:B, 7ni6:A, 7ni6:B, 8oxq:A, 8oxq:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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