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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SSHHHHHHSSSMNGIRWIASYPKAGNTWVRCMLAAYITGKAPQVWNDIDAESLTLEAMLRFGDLPPAEPMEPVLVKTHLK
ADVPVLGLYGEATAKVLYLVRNPRDMLLSSMRMASISRDDVEKSRDFARKFIANEGLGWNALGAGGGVGLGSWPENVRSW
TESSSDRFPNADVLTMRYEDLKGDPVARFSEIVEFLDLGGPVDIEDIRRAVAASTLERMRELEKRSGGSPIMMKGGPGGA
RPQFVGEGRYDQSLSFLGEDIESDYQELLHGDSGFALYAKQYGYAG

The query sequence (length=286) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3mgb:A 286 286 1.0000 1.0000 1.0000 0.0 3mgb:B
2 3mg9:A 255 278 0.8776 0.9843 0.9029 1.05e-180 3mgc:A
3 4eec:A 253 269 0.4685 0.5296 0.4981 7.82e-80 2ovb:A, 2ovf:A
4 1aqy:A 283 241 0.2273 0.2297 0.2697 2.46e-15 1aqu:A, 1aqu:B, 1aqy:B, 1bo6:A, 1bo6:B
5 2zyt:X 291 246 0.2203 0.2165 0.2561 1.19e-14 2zpt:X, 2zvp:X, 2zvq:X, 2zyu:X, 2zyv:X, 2zyw:X
6 2h8k:A 245 270 0.2133 0.2490 0.2259 4.52e-12 2h8k:B, 2reo:A
7 3bfx:A 253 213 0.1923 0.2174 0.2582 2.62e-11 3bfx:B
8 3ckl:B 296 255 0.2133 0.2061 0.2392 3.18e-11 3ckl:A, 2z5f:A, 2z5f:B
9 5x2b:L 283 221 0.1923 0.1943 0.2489 8.13e-11 5x2b:C, 5x2b:A, 5x2b:B, 5x2b:D, 5x2b:E, 5x2b:F, 5x2b:G, 5x2b:H, 5x2b:I, 5x2b:J, 5x2b:K
10 7v1o:A 288 212 0.1783 0.1771 0.2406 1.37e-10 7v1o:B
11 4jvl:A 292 247 0.2203 0.2158 0.2551 4.42e-10 1g3m:A, 1g3m:B, 1hy3:A, 1hy3:B, 4jvl:B, 4jvm:A, 4jvm:B, 4jvn:A, 4jvn:B
12 2gwh:B 288 259 0.2098 0.2083 0.2317 5.25e-10 2gwh:A
13 1q20:A 294 207 0.1818 0.1769 0.2512 9.36e-10 1q1q:A, 1q1z:A, 1q22:A
14 1j99:A 284 211 0.1923 0.1937 0.2607 9.50e-10 1efh:A, 1efh:B, 3f3y:A, 3f3y:B, 3f3y:C, 3f3y:D, 4ifb:A, 4ifb:B, 1ov4:A, 2qp3:A, 2qp4:A
15 3u3k:A 289 280 0.2517 0.2491 0.2571 1.36e-09 2a3r:A, 2a3r:B, 2d06:A, 2d06:B, 4gra:A, 4gra:B, 1ls6:A, 3qvu:A, 3qvu:B, 3qvv:A, 3qvv:B, 3u3j:A, 3u3j:B, 3u3k:B, 3u3m:A, 3u3o:A, 3u3r:A, 1z28:A, 1z29:A
16 7eov:A 274 234 0.1993 0.2080 0.2436 1.68e-07 7d1x:A, 7d1x:B
17 7r0s:A 336 201 0.1643 0.1399 0.2338 6.68e-05 7r0s:B, 7r0u:A, 7r0u:B
18 1x8k:A 344 228 0.2063 0.1715 0.2588 0.008 1fmj:A, 1fmj:B, 1fml:A, 1fml:B, 1x8j:A, 1x8j:B, 1x8k:B, 1x8l:A, 1x8l:B
19 8k9y:A 322 230 0.1678 0.1491 0.2087 0.009 8k9y:B
20 5mek:A 322 192 0.1259 0.1118 0.1875 0.060 5mex:A
21 1fui:A 591 70 0.0769 0.0372 0.3143 1.2 1fui:B, 1fui:C, 1fui:D, 1fui:E, 1fui:F, 6k1f:A, 6k1f:B, 6k1f:C, 6k1f:D, 6k1f:E, 6k1f:F, 6k1g:A, 6k1g:B, 6k1g:C, 6k1g:D, 6k1g:E, 6k1g:F
22 1wz2:A 948 22 0.0385 0.0116 0.5000 2.4 1wz2:B
23 4pr3:A 205 57 0.0559 0.0780 0.2807 3.0 4pr3:B
24 3a9r:A 589 65 0.0734 0.0357 0.3231 3.3 3a9r:B, 3a9r:C, 3a9s:A, 3a9s:B, 3a9s:C, 3a9t:A, 3a9t:B, 3a9t:C
25 4gbm:A 283 238 0.1923 0.1943 0.2311 3.4
26 2byc:A 137 51 0.0524 0.1095 0.2941 7.9 2byc:B
27 2eix:A 243 79 0.0664 0.0782 0.2405 8.3 2eix:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218