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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SSHHHHHHSMPDNTIQWDKDADGIVTLTMDDPSGSTNVMNEAYIESMGKAVDRLVAEKDSITGVVVASAKKTFFAGGDVK
TMIQARPEDAGDVFNTVETIKRQLRTLETLGKPVVAAINGAALGGGLEIALACHHRIAADVKGSQLGLPEVTLGLLPGGG
GVTRTVRMFGIQNAFVSVLAQGTRFKPAKAKEIGLVDELVATVEELVPAAKAWIKEELKANPDGAGVQPWDKKGYKMPGG
TPSSPGLAAILPSFPSNLRKQLKGAPMPAPRAILAAAVEGAQVDFDTASRIESRYFASLVTGQVAKNMMQAFFFDLQAIN
AGGSRPEGIGKTPIKRIGVLGAGMMGAGIAYVSAKAGYEVVLKDVSLEAAAKGKGYSEKLEAKALERGRTTQERSDALLA
RITPTADAADFKGVDFVIEAVFENQELKHKVFGEIEDIVEPNAILGSNTSTLPITGLATGVKRQEDFIGIHFFSPVDKMP
LVEIIKGEKTSDEALARVFDYTLAIGKTPIVVNDSRGFFTSRVIGTFVNEALAMLGEGVEPASIEQAGSQAGYPAPPLQL
SDELNLELMHKIAVATRKGVEDAGGTYQPHPAEAVVEKMIELGRSGRLKGAGFYEYADGKRSGLWPGLRETFKSGSSQPP
LQDMIDRMLFAEALETQKCLDEGVLTSTADANIGSIMGIGFPPWTGGSAQFIVGYSGPAGTGKAAFVARARELAAAYGDR
FLPPESLLS

The query sequence (length=729) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8oqs:B 735 734 1.0000 0.9918 0.9932 0.0 4b3i:A, 4b3i:B, 4b3j:A, 4b3j:B, 7o4s:A, 7o4s:B, 7o4t:A, 7o4t:B, 7o4u:A, 7o4u:B, 7o4v:B, 7o4v:A, 8opu:A, 8opu:B, 8opv:A, 8opv:B, 8oql:A, 8oql:B, 8oqn:A, 8oqn:B, 8oqo:A, 8oqo:B, 8oqp:A, 8oqp:B, 8oqq:A, 8oqq:B, 8oqr:A, 8oqr:B, 8oqs:A, 8oqt:B, 8oqt:A, 8oqu:A, 8oqu:B, 8oqv:A, 8oqv:B, 8pf8:A, 8pf8:B
2 6ysw:A 707 721 0.3402 0.3508 0.3440 8.16e-97
3 1wdl:A 715 708 0.3292 0.3357 0.3390 6.71e-95 2d3t:A, 2d3t:B, 1wdk:A, 1wdk:B, 1wdl:B, 1wdm:A, 1wdm:B
4 6tnm:A 719 701 0.3251 0.3296 0.3381 4.12e-94
5 6iun:B 692 689 0.2867 0.3020 0.3033 2.43e-84 6iun:A
6 3zwa:A 727 655 0.2565 0.2572 0.2855 8.96e-58 5mgb:A, 5mgb:B, 5omo:A, 5omo:B, 2x58:A, 2x58:B, 6z5f:AAA, 6z5f:BBB, 6z5o:AAA, 6z5v:AAA, 6z5v:BBB, 6zib:AAA, 6zib:BBB, 6zic:AAA, 6zic:BBB, 3zw9:A, 3zw9:B, 3zwa:B, 3zwb:A, 3zwb:B, 3zwc:A, 3zwc:B
7 6aa8:E 281 287 0.1427 0.3701 0.3624 1.76e-52 6aa8:F
8 4pzd:A 283 287 0.1509 0.3887 0.3833 3.95e-49 4pzd:B, 4pzd:C, 4pzd:D, 4pzd:E, 4pzd:F, 4pzd:G, 4pzd:H, 4pzd:I, 4pze:A, 4pze:B, 4pze:C, 4pze:D, 4pze:G, 4pze:E, 4pze:F, 4pze:H, 4pze:I
9 4kug:A 282 286 0.1385 0.3582 0.3531 7.06e-48 4kug:B, 4kug:C, 4kug:D, 4kuh:A, 4kuh:B, 4kuh:C, 4kuh:D, 4kuh:E, 4kuh:F, 4kuh:G, 4kuh:H
10 3k6j:A 430 364 0.1372 0.2326 0.2747 6.24e-45
11 1f12:A 293 296 0.1385 0.3447 0.3412 1.91e-42 1f0y:A, 1f0y:B, 1f17:A, 1f17:B, 3had:A, 3had:B, 2hdh:A, 2hdh:B, 3hdh:A, 3hdh:B, 3hdh:C, 1il0:A, 1il0:B, 1lsj:A, 1lsj:B, 1lso:A, 1lso:B, 1m75:A, 1m75:B, 1m76:A, 1m76:B
12 5zai:C 259 192 0.0974 0.2741 0.3698 3.25e-24 5zai:A, 5zai:B, 5zai:E
13 4om8:A 309 259 0.1043 0.2460 0.2934 2.01e-23 4om8:B
14 5jbx:B 261 184 0.0892 0.2490 0.3533 1.21e-22 5jbx:A
15 6eqo:A 1804 271 0.1180 0.0477 0.3173 2.71e-21 6eqo:B
16 4dyd:A 283 290 0.1070 0.2756 0.2690 1.39e-18 4e13:A
17 1dub:A 260 180 0.0823 0.2308 0.3333 2.04e-17 1dub:B, 1dub:C, 1dub:E, 1dub:F, 1dub:D, 2dub:A, 2dub:B, 2dub:C, 2dub:E, 2dub:F, 2dub:D, 1ey3:A, 1ey3:B, 1ey3:C, 1ey3:D, 1ey3:E, 1ey3:F, 1mj3:A, 1mj3:B, 1mj3:C, 1mj3:E, 1mj3:F
18 3h81:A 256 202 0.0933 0.2656 0.3366 8.14e-16 3h81:C, 3q0g:C, 3q0g:D, 3q0g:F, 3q0j:C, 3q0j:F
19 2hw5:C 260 174 0.0754 0.2115 0.3161 1.15e-15
20 3f3s:A 312 221 0.0809 0.1891 0.2670 2.61e-14 3f3s:B
21 3adp:A 310 207 0.0809 0.1903 0.2850 1.96e-13
22 1xx4:A 254 179 0.0754 0.2165 0.3073 1.07e-12
23 6p5u:E 246 192 0.0823 0.2439 0.3125 1.75e-12 6p5u:A, 6p5u:B, 6p5u:C, 6p5u:D, 6p5u:F
24 4i42:A 285 221 0.0837 0.2140 0.2760 3.02e-11 4els:A, 4els:B, 4els:C, 4els:D, 4els:E, 4els:F, 4elw:A, 4elw:B, 4elw:C, 4elw:D, 4elw:E, 4elw:F, 4elx:A, 4elx:B, 4elx:C, 4elx:D, 4elx:F, 3h02:A, 3h02:B, 3h02:C, 3h02:D, 3h02:E, 3h02:F, 4i42:F, 4i42:B, 4i42:D, 4i42:C, 4i42:E, 4i42:G, 4i42:L, 4i42:H, 4i42:J, 4i42:I, 4i42:K, 3t88:A, 3t88:E, 3t88:B, 3t88:F, 3t88:C, 3t88:D
25 4izc:B 266 183 0.0658 0.1805 0.2623 1.98e-10 4izc:A, 4izd:A, 4izd:B
26 2vss:B 247 186 0.0782 0.2308 0.3065 4.13e-10 6l3p:A, 6l3p:B, 2vss:D, 2vss:E, 2vss:F, 2vsu:A, 2vsu:B, 2vsu:D, 2vsu:E, 2vsu:F
27 1sg4:B 258 179 0.0686 0.1938 0.2793 2.74e-09
28 1jxz:B 269 270 0.0974 0.2639 0.2630 1.59e-08 1jxz:A, 1jxz:C, 1nzy:A, 1nzy:B, 1nzy:C
29 3p85:A 224 189 0.0768 0.2500 0.2963 1.07e-07
30 6slb:AAA 257 196 0.0741 0.2101 0.2755 1.34e-07 6sla:AAA, 6sla:BBB, 6sla:CCC, 6sla:DDD, 6sla:EEE, 6sla:FFF
31 2a81:A 235 189 0.0658 0.2043 0.2540 6.01e-07
32 3pe8:A 219 193 0.0713 0.2374 0.2694 2.60e-06
33 7bor:A 247 149 0.0590 0.1741 0.2886 3.82e-06 7bor:C
34 4jvt:A 257 90 0.0425 0.1206 0.3444 4.87e-06 4omr:A
35 2uzf:A 260 201 0.0700 0.1962 0.2537 6.24e-06
36 4i4z:A 275 175 0.0658 0.1745 0.2743 2.22e-05 4eml:A, 4eml:B, 4eml:C, 4eml:D, 4eml:E, 4eml:F, 4i4z:F, 4i4z:B, 4i4z:D, 4i4z:C, 4i4z:E, 4i4z:G, 4i4z:H, 4i4z:I, 4i52:A, 4i52:B, 4i52:C, 4i52:D, 4i52:E, 4i52:F, 4i52:G, 4i52:H, 4i52:I
37 7xwt:B 277 92 0.0412 0.1083 0.3261 2.30e-05 7xwv:A, 7xwv:B
38 5duf:A 245 221 0.0727 0.2163 0.2398 2.49e-05 5dtw:A, 5dtw:D, 5du4:A, 5du6:A, 5du6:B, 5du6:C, 5du8:A, 5du8:B, 5du8:C, 5duc:A, 5duc:B, 5duc:C
39 3ome:C 247 187 0.0686 0.2024 0.2674 3.88e-05 3ome:A, 3ome:B, 3ome:D, 3ome:E, 3ome:F
40 3bpt:A 362 207 0.0672 0.1354 0.2367 6.99e-05
41 4fnb:A 232 197 0.0700 0.2198 0.2589 1.35e-04 4fn8:A, 4fnd:A
42 1ef9:A 261 198 0.0604 0.1686 0.2222 2.22e-04 6n92:A, 6n92:B, 6n92:C, 6n92:D, 6n92:E, 6n92:F, 6n93:A, 6n93:B, 6n93:C, 6n93:D, 6n93:E, 6n93:F, 6n94:A, 6n94:B, 6n94:C, 6n94:D, 6n94:E, 6n94:F, 6n95:A, 6n95:B, 6n95:C, 6n95:D, 6n95:E, 6n95:F, 6n96:A, 6n96:B, 6n96:C, 6n96:D, 6n96:E, 6n96:F, 6n97:A, 6n97:B, 6n97:C, 6n97:D, 6n97:E, 6n97:F
43 3t3w:F 248 123 0.0453 0.1331 0.2683 4.72e-04 3t3w:A, 3t3w:B, 3t3w:C, 3t3w:D, 3t3w:E
44 3rrv:B 254 205 0.0727 0.2087 0.2585 0.008 3rrv:A, 3rrv:C, 3rrv:D, 3rrv:E, 3rrv:F
45 5ts5:A 483 47 0.0261 0.0393 0.4043 0.037 4e0v:A, 4e0v:B, 5ts5:B, 5ts5:C, 5ts5:D
46 5kag:D 423 89 0.0384 0.0662 0.3146 0.25 5kag:A, 5kag:B, 5kag:C, 5kag:E, 5kag:F, 5kag:G, 5kag:H, 5kag:I, 5kag:J, 5kag:K, 5kag:L, 5kah:A, 5kah:B, 5kah:C, 5kah:D, 5kah:E, 5kah:F, 5kah:G, 5kah:H, 5kah:I, 5kah:J, 5kah:K, 5kah:L, 5kaj:A, 5kaj:B, 5kaj:C, 5kaj:D, 5kaj:E, 5kaj:F, 5kaj:G, 5kaj:H, 5kaj:I, 5kaj:J, 5kaj:K, 5kaj:L, 2np9:A, 2np9:B, 2np9:C, 2pg8:A, 2pg8:B, 2pg8:C, 4ylh:A, 4ylh:B, 4ylh:C, 4ylh:D, 4ylh:E, 4ylh:F, 4ylh:G, 4ylh:H, 4ylh:I, 4ylh:J, 4ylh:K, 4ylh:L
47 8ghm:A 391 109 0.0439 0.0818 0.2936 0.26 8ghm:G
48 4hdt:A 340 184 0.0631 0.1353 0.2500 0.31
49 1szo:D 251 192 0.0604 0.1753 0.2292 0.58 1szo:A, 1szo:B, 1szo:C, 1szo:E, 1szo:F, 1szo:G, 1szo:H, 1szo:I, 1szo:J, 1szo:K, 1szo:L
50 5jox:A 502 59 0.0233 0.0339 0.2881 0.77 5jox:B, 5joy:A, 5joy:B
51 1bh6:A 274 77 0.0274 0.0730 0.2597 0.78
52 4qii:B 301 152 0.0521 0.1262 0.2500 0.86 1q51:B, 4qii:A, 4qii:F, 4qii:E, 4qii:C, 4qii:D, 4qii:G, 4qii:L, 4qii:H, 4qii:K, 4qii:I, 4qii:J, 4qij:A, 4qij:F, 4qij:B, 4qij:E, 4qij:C, 4qij:D, 4qij:G, 4qij:K, 4qij:H, 4qij:J, 4qij:I, 4qij:L
53 2bc0:A 473 144 0.0604 0.0930 0.3056 0.89 2bc0:B, 2bc1:A, 2bc1:B, 2bcp:A, 2bcp:B
54 2fn7:A 317 85 0.0357 0.0820 0.3059 1.1 2fn7:B, 4nd1:A, 4nd1:B, 4nd2:A, 4nd2:B, 4nd3:A, 4nd3:B, 4nd4:A, 4nd4:B
55 6j0p:A 564 145 0.0508 0.0656 0.2552 1.5 6j0p:B, 6j1e:A, 6j1f:A, 6j1f:B, 6j1g:A, 6j1i:A, 6j1j:A
56 1rjn:B 275 133 0.0439 0.1164 0.2406 1.8 1q51:A, 1q51:C, 1q51:D, 1q51:E, 1q51:F, 1q51:G, 1q51:H, 1q51:I, 1q51:J, 1q51:K, 1q51:L, 1rjm:A, 1rjm:B, 1rjm:C, 1rjn:A, 1rjn:C, 3t8a:B, 3t8a:C
57 1reo:A 484 47 0.0233 0.0351 0.3617 1.9 1tdk:A, 1tdn:A, 1tdo:A
58 4r16:A 418 87 0.0357 0.0622 0.2989 3.4 4r16:B
59 5z2g:A 477 32 0.0219 0.0335 0.5000 3.5 5z2g:B
60 2j5s:A 250 105 0.0357 0.1040 0.2476 3.6 2j5s:B
61 4w8y:A 835 123 0.0398 0.0347 0.2358 3.7 4w8y:B
62 5je8:B 294 39 0.0219 0.0544 0.4103 4.0 5je8:A, 5je8:C, 5je8:D
63 3kve:A 484 55 0.0274 0.0413 0.3636 4.5 3kve:B, 3kve:C, 3kve:D
64 5er0:A 450 30 0.0192 0.0311 0.4667 5.2 5er0:B, 5er0:C, 5er0:D, 5vn0:A, 5vn0:B, 5vn0:C, 5vn0:D, 5vn0:E, 5vn0:F, 5vn0:G, 5vn0:H, 5voh:A, 5voh:B, 5voh:C, 5voh:D
65 4plf:B 330 88 0.0357 0.0788 0.2955 5.3 4plc:A, 4plc:B, 4plc:C, 4plc:D, 4plf:A, 4plg:A, 4plg:B, 6vdj:A
66 4ffl:A 353 70 0.0302 0.0623 0.3143 5.4 4ffm:A, 4ffn:A, 4ffo:A, 4ffp:A, 4ffr:A
67 6vpb:B 324 46 0.0233 0.0525 0.3696 6.3
68 1f8r:A 483 42 0.0206 0.0311 0.3571 6.4 1f8r:B, 1f8r:C, 1f8r:D, 1f8s:A, 1f8s:B, 1f8s:C, 1f8s:D, 1f8s:E, 1f8s:F, 1f8s:G, 1f8s:H, 2iid:A, 2iid:B, 2iid:C, 2iid:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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