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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SRYEKWEKIKQHYQHWSDSLSEEGRGLLKKLQIPIEPKKDDIIHSLSQEEKELLKRIQIDSSDFLSTEEKEFLKKLQIDP
LSEKEKEFLKKLKLDIQPYDINQRLQDTGGLIDSPSINLDVRKQYKRDIQNIDALLHQSIGSTLYNKIYLYENMNINNLT
ATLGADLVDSTDNTKINRGIFNEFKKNFKYSISSNYMIVDINERPALDNERLKWRIQLSPDTRAGYLENGKLILQRNIGL
EIKDVQIIKQSEKEYIRIDAKVVPKSKIDTKIQEAQLNINQEWNKALGLPKYTKLITFNVHNRYASNIVESAYLILNEWK
NNIQSDLIKKVTNYLVDGNGRFVFTDITLPNIAEQYTHQDEIYEQVHSKGLYVPESRSILLHGPSKGVELRNDSEGFIHE
FGHAVDDYAGYLLDKNQSDLVTNSKKFIDIFKEEGSNLTSYGRTNEAEFFAEAFRLMHSTDHAERLKVQKNAPKTFQFIN
DQIKFIINS

The query sequence (length=489) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1zxv:A 728 489 0.9980 0.6703 0.9980 0.0 1j7n:A, 4pkw:A, 1pww:A
2 1jky:A 748 511 1.0000 0.6537 0.9569 0.0 5d1s:A, 5d1t:A, 5d1u:A, 4dv8:A, 1j7n:B, 4pkq:A, 4pkr:A, 4pks:A, 4pkt:A, 4pku:A, 4pkv:A, 1pwp:A, 1pwp:B, 1pwq:A, 1pwq:B, 1pwu:A, 1pwu:B, 1pwv:A, 1pwv:B, 1pww:B, 4wf6:A, 4xm6:A, 4xm7:A, 4xm8:A, 1yqy:A, 1zxv:B
3 6pek:D 293 66 0.0409 0.0683 0.3030 1.3 6pek:A, 6pek:B, 6pek:C, 6pek:E, 6pen:A, 6pen:B, 6pen:C, 6pen:D, 6pen:E, 5z6r:A
4 6p07:B 303 66 0.0348 0.0561 0.2576 1.4 6nyv:B, 6nyw:B, 6p07:C, 6p07:D, 6p07:E, 6p07:F, 6p10:B, 6p11:B, 6p12:B, 6p13:B
5 8jhz:A 2615 121 0.0695 0.0130 0.2810 1.9
6 6p14:A 265 61 0.0348 0.0642 0.2787 2.7
7 2h8k:A 245 74 0.0389 0.0776 0.2568 3.1 2h8k:B, 2reo:A
8 5f5x:A 344 70 0.0470 0.0669 0.3286 3.1 5f5x:B, 5jyb:A
9 7u0u:A 195 52 0.0327 0.0821 0.3077 4.0 6tz7:B
10 6jpk:A 409 33 0.0266 0.0318 0.3939 4.4 6jpk:B
11 4be9:A 538 93 0.0613 0.0558 0.3226 5.3 4be9:B, 4upd:A, 4upd:B
12 7vm0:B 406 84 0.0429 0.0517 0.2500 5.7 8h5d:A, 8h5d:B, 7vm0:A
13 5f9z:A 493 66 0.0470 0.0467 0.3485 5.8 5f9y:A, 5f9y:B, 5f9z:B, 5xio:A, 5xio:B
14 7pog:A 2382 88 0.0511 0.0105 0.2841 5.8 4dmw:A, 3ho6:A, 3ho6:B, 4r04:A, 3srz:A, 3ss1:A, 7u2p:A, 7uby:B, 7uby:A, 5uqk:A, 5uql:A
15 6zr7:AAA 292 149 0.0798 0.1336 0.2617 7.4
16 7v8i:D 229 46 0.0307 0.0655 0.3261 7.8 7arj:F, 7arj:D, 7ark:D, 7ark:F, 7arl:F, 7arl:D, 7mdy:D, 7mdy:C, 7v8i:F
17 4qnu:A 323 64 0.0409 0.0619 0.3125 8.0 4qnu:B, 4qnu:C, 4qnu:D, 4qnu:E, 4qnu:F, 4qnu:G, 4qnu:H, 4qnv:A, 4qnv:B
18 7t18:A 439 69 0.0491 0.0547 0.3478 8.6 2aq4:A, 3bjy:A, 3osp:A, 7t19:A, 7t1a:A, 7t1b:A, 5wm1:A, 5wm8:A, 5wmb:A, 6x6z:A, 6x70:A, 6x71:A, 6x72:A, 6x73:A, 6x74:A, 6x75:A, 6x76:A, 6x77:A
19 5imt:D 77 31 0.0245 0.1558 0.3871 9.1
20 4uqa:A 391 79 0.0389 0.0486 0.2405 9.3 5a6l:A, 5a6m:A, 4ckq:A, 4uqc:A
21 4odj:A 386 70 0.0389 0.0492 0.2714 9.4 6c07:A, 6c07:B, 6c07:C, 6ltv:A, 6ltv:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218