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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SRVSTRSSLAEDLRAIGLADGDAVLVHAALRKVGKIVGGPDDILDAMRDVIGPAGTVLGYADWQLEDEIRDDPAMREHIP
AFDPLRSRSIRDNGFWPELIRTTPGALRSASPGASMAAIGGEAEWFTADHALDYGYGPRSPLGKLVEAKGKVLMLGAPLD
TMTLLAHAEHLADFPNKRILRYEAPILVDGEKVWRWFEEFDTSDPPDGLADDYFAGIVEEFLATGRGKRGKIGEASSVLV
PADEIVAFAVDWLERWGRT

The query sequence (length=259) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5ht0:C 261 259 0.9961 0.9885 0.9961 0.0 5ht0:A, 5ht0:B, 5ht0:D, 5ht0:E, 5ht0:F, 7kes:A, 7kes:B, 6mn0:A, 6mn0:B, 6mn0:C, 6mn0:F, 6mn0:D, 6mn0:E, 6mn1:A, 6mn1:B, 6mn2:A, 6mn2:B
2 6mb6:A 268 259 0.6293 0.6082 0.6293 1.06e-101 6mb4:B, 6mb5:A, 6mb6:C, 6mb7:A, 6mb9:A, 6mb9:B, 6mb9:D, 6mb9:C
3 7q1d:D 272 260 0.4710 0.4485 0.4692 6.93e-75 7mqk:A, 7mqk:B, 7mqk:C, 7mqk:D, 7mql:A, 7mql:B, 7mql:C, 7mql:D, 7mqm:A, 7mqm:B, 7mqm:C, 7mqm:D, 7q0q:A, 7q0q:B, 7q10:A, 7q1d:A, 7q1d:B, 7q1d:C, 7q1x:A
4 6bc2:A 268 264 0.3745 0.3619 0.3674 7.21e-51 6bbz:A, 6bc3:A, 6bc4:A, 6bc5:A, 6bc7:A, 6np2:A, 6np3:A, 6np4:A, 6np5:A, 6nti:A, 6ntj:A, 6o5u:A
5 2nyg:A 270 261 0.3359 0.3222 0.3333 1.32e-37 2nyg:B, 2nyg:C, 2nyg:D, 2nyg:E
6 3kzl:A 266 266 0.3089 0.3008 0.3008 2.27e-30 3ijw:A, 3ijw:B, 3kzl:D, 3kzl:C, 3kzl:B, 3n0m:A, 3n0m:B, 3n0s:A, 3n0s:D, 3n0s:C, 3n0s:B, 3slb:A, 3slb:D, 3slb:C, 3slb:B, 3slf:A, 3slf:B
7 3sma:B 268 260 0.3359 0.3246 0.3346 3.54e-30 3sma:A, 3sma:C, 3sma:D
8 6mn5:D 260 250 0.3012 0.3000 0.3120 7.59e-18 6mn3:A, 6mn3:B, 6mn4:A, 6mn4:B, 6mn4:C, 6mn4:D, 6mn4:E, 6mn4:F, 6mn5:A, 6mn5:B, 6mn5:C, 6mn5:E, 6mn5:F
9 4fgo:A 181 46 0.0656 0.0939 0.3696 1.0
10 7kcl:B 614 86 0.0965 0.0407 0.2907 4.1 7c04:A, 7c7b:A, 5f5r:A, 5f5r:B, 5hph:A, 5hph:B, 7kck:A, 7kck:B, 7kcl:A, 7kcm:A, 7kcm:B, 7klu:A, 7klu:B, 7klu:D, 7klu:C, 7klv:A, 7klv:B, 6xg6:A, 6xg6:B, 4z1i:A, 4z1i:B, 4z1i:C, 4z1i:D
11 2xnj:A 255 58 0.0695 0.0706 0.3103 5.6 1fdr:A, 2xnj:B
12 6io1:B 448 30 0.0579 0.0335 0.5000 6.0 6io1:A
13 5z79:C 599 48 0.0579 0.0250 0.3125 8.3 5z79:A, 5z79:D, 5z79:E, 5z79:F
14 5tth:B 621 67 0.0849 0.0354 0.3284 8.5 6d14:B, 7exp:B, 4ipe:B, 4iyn:B, 4j0b:B, 5tvu:B, 5tvw:B, 5tvx:B
15 3zqx:A 146 65 0.0811 0.1438 0.3231 9.2
16 5z79:B 562 48 0.0579 0.0267 0.3125 9.4

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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