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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SRTACKRCRLKKIKCDQEFPSCKRCAKLEVPCVSLDPATGKDVPRSYVFFLEDRLAVMMRVLKEYGVDPTKIRGNIPATS
DDEPFDLK

The query sequence (length=88) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1pyi:A 88 88 1.0000 1.0000 1.0000 1.62e-60 1pyi:B
2 3coq:A 89 53 0.2386 0.2360 0.3962 7.83e-04 3coq:B, 1d66:A, 1d66:B, 7uik:T, 7uik:U, 7uio:GA, 7uio:GB
3 1aw6:A 43 29 0.1705 0.3488 0.5172 0.018
4 1cld:A 33 30 0.1591 0.4242 0.4667 0.022
5 8aaf:S 106 53 0.2159 0.1792 0.3585 0.053 8agt:S, 8agu:S, 8agv:S, 8agw:S, 8agx:S, 8agz:S, 5apn:f, 5apo:f, 7azy:v, 7b7d:Lb, 8bip:Lf, 8bjq:Lf, 8bn3:O3, 8bqd:BK, 8bqx:BK, 7bt6:f, 7btb:f, 6c0f:f, 6cb1:f, 8ccs:R, 8cdl:R, 8cdr:R, 8ceh:R, 8cf5:R, 8cg8:R, 8cgn:R, 8civ:R, 8cku:R, 8cmj:R, 5dat:O3, 5dat:o3, 5dc3:O3, 5dc3:o3, 5dge:O3, 5dge:o3, 5dgf:O3, 5dgf:o3, 5dgv:O3, 5dgv:o3, 6elz:f, 6em1:f, 6em3:f, 6em4:f, 6em5:f, 8eub:Af, 8evp:Af, 8evq:Af, 8evr:Af, 8evs:Af, 8evt:Af, 8ewb:Af, 8ewc:Af, 5fci:O3, 5fci:o3, 5fcj:O3, 5fcj:o3, 6ft6:f, 5gak:h, 6gq1:f, 6gqb:f, 6gqv:f, 5h4p:f, 6hd7:h, 8hfr:f7, 6hhq:AG, 6hhq:DH, 5i4l:O3, 5i4l:o3, 6i7o:BK, 6i7o:YK, 3j6x:73, 3j6y:73, 3j77:83, 3j78:83, 3jct:f, 5jcs:f, 5juo:KA, 5jup:KA, 5jus:KA, 5jut:KA, 5juu:KA, 8k2d:Lf, 8k82:Lf, 5lyb:O3, 5lyb:o3, 5m1j:f5, 6m62:f, 5mc6:BK, 5mei:AG, 5mei:DH, 7mpi:Af, 7mpj:Af, 6n8j:f, 6n8k:f, 6n8l:f, 6n8m:s, 6n8n:s, 6n8o:s, 7n8b:Af, 7nac:f, 5ndg:O3, 5ndg:o3, 5ndv:O3, 5ndv:o3, 5ndw:O3, 5ndw:o3, 7nrc:Lh, 7nrd:Lh, 5obm:O3, 5obm:o3, 7of1:f, 7oh3:f, 7ohp:f, 7ohq:f, 7ohr:f, 7ohs:f, 7oht:f, 7ohu:f, 7ohv:f, 7ohw:f, 7ohx:f, 7ohy:f, 6oig:f, 5on6:AG, 5on6:DH, 7osa:eL33, 7osm:eL33, 8p8m:RF, 8p8n:RF, 8p8u:RF, 8pfr:RF, 6q8y:BK, 6qik:f, 6qt0:f, 6qtz:f, 7r7a:f, 6r84:h, 6r86:h, 6r87:h, 6ri5:f, 7rr5:Lf, 6rzz:f, 6s05:f, 6s47:Ah, 6snt:ak, 6sv4:BK, 6sv4:YK, 6sv4:ZK, 6t4q:Lf, 5t62:s, 5t6r:s, 6t7i:Lf, 6t7t:Lf, 6t83:fy, 6t83:Q, 5tbw:AG, 5tbw:DH, 6tb3:BK, 5tga:O3, 5tga:o3, 5tgm:O3, 5tgm:o3, 6tnu:BK, 7too:AL33, 7top:AL33, 7u0h:f, 4u3m:O3, 4u3m:o3, 4u3n:O3, 4u3n:o3, 4u3u:O3, 4u3u:o3, 4u4n:O3, 4u4n:o3, 4u4o:O3, 4u4o:o3, 4u4q:O3, 4u4q:o3, 4u4r:O3, 4u4r:o3, 4u4u:O3, 4u4u:o3, 4u4y:O3, 4u4y:o3, 4u4z:O3, 4u4z:o3, 4u50:O3, 4u50:o3, 4u51:O3, 4u51:o3, 4u52:O3, 4u52:o3, 4u53:O3, 4u53:o3, 4u55:O3, 4u55:o3, 4u56:O3, 4u56:o3, 4u6f:O3, 4u6f:o3, 7ug6:f, 7uoo:f, 7uqb:f, 7uqz:f, 7v08:f, 4v6i:Bj, 4v7f:e, 4v88:Bf, 4v88:Df, 4v8t:f, 4v8y:Bf, 4v8z:Bf, 8v83:f, 8v84:f, 8v87:f, 4v91:f, 6woo:f, 6xiq:f, 6xir:f, 8y0u:Lf, 6ylg:f, 6ylh:f, 6ylx:f, 6yly:f, 5z3g:j, 7z34:f, 6z6j:Lf, 6z6k:Lf, 7zpq:Be, 7zrs:Be, 7zs5:Bg, 7zuw:Be, 7zux:Ee, 7zw0:Li
6 2er8:A 68 62 0.2386 0.3088 0.3387 0.15 2er8:B, 2er8:C, 2er8:D, 2ere:A, 2ere:B, 2erg:A, 2erg:B
7 8e5t:f 88 56 0.2045 0.2045 0.3214 0.47
8 5h2c:A 251 51 0.2159 0.0757 0.3725 0.76
9 8c3a:AG 106 53 0.2045 0.1698 0.3396 0.81 8c3a:CA, 8cq7:AG, 8cq7:CA, 8cqw:AG, 8cqw:CA, 8cre:AG, 8cre:CA, 8oeq:AG, 8oeq:CA, 7pzy:AG, 7q08:AG, 7q0f:AG, 7q0p:AG, 7q0r:AG, 8q5i:AG
10 2hap:C 76 26 0.1364 0.1579 0.4615 0.89 2hap:D, 1hwt:C, 1hwt:D, 1hwt:G, 1hwt:H, 1pyc:A, 1qp9:A, 1qp9:B, 1qp9:C, 1qp9:D
11 6gys:B 579 27 0.1250 0.0190 0.4074 0.95 6f07:B, 6gyp:B, 6gys:C, 6gys:J, 6gys:I, 6gyu:B, 7k7g:M, 8ow1:CE
12 8ewy:A 1049 36 0.1364 0.0114 0.3333 1.0 6aah:A, 6aah:B, 6bbu:A, 6c7y:A, 6dbn:A, 5e1e:A, 5e1e:B, 4e4l:A, 4e4l:E, 4e4l:B, 4e4l:D, 4e4n:A, 4e4n:B, 4e5w:A, 4e5w:B, 4ehz:A, 4ehz:B, 4ehz:C, 4ehz:D, 4ei4:A, 4ei4:B, 6elr:A, 6elr:B, 8ewy:B, 3eyg:A, 3eyh:A, 4fk6:A, 4fk6:B, 6ggh:A, 6ggh:B, 5hx8:A, 5hx8:B, 6hzu:A, 6hzu:B, 4i5c:A, 4i5c:B, 4ivb:A, 4ivb:B, 4ivc:A, 4ivc:B, 4ivd:A, 4ivd:B, 4k6z:A, 4k77:A, 4k77:B, 5khw:A, 5khw:B, 5khx:A, 6n77:A, 6n77:B, 6n78:A, 6n79:A, 6n7a:A, 6n7a:B, 6n7b:A, 6n7c:A, 6n7c:B, 6n7d:A, 6rsb:A, 6rsb:B, 6rsc:A, 6rsc:B, 6rsd:A, 6rsd:B, 6rse:A, 6rse:B, 6rsh:A, 6rsh:B, 6sm8:A, 6sm8:B, 6smb:A, 6smb:B, 7t6f:A, 7t6f:B, 6tpe:A, 6tpe:B, 6tpf:A, 6tpf:B, 6w8l:A, 5wo4:A, 5wo4:B
13 1qhg:A 622 35 0.1591 0.0225 0.4000 1.4
14 3pjr:A 646 35 0.1591 0.0217 0.4000 1.4 2pjr:A, 2pjr:B, 2pjr:F, 2pjr:G, 1qhh:A, 1qhh:D
15 1ajy:A 71 53 0.1932 0.2394 0.3208 1.7 1ajy:B, 1zme:C, 1zme:D
16 5it7:ff 105 66 0.2500 0.2095 0.3333 2.5 6uz7:Bf
17 7aoe:B 1174 28 0.1364 0.0102 0.4286 2.6 7aoc:B, 7aod:B, 7aod:N
18 6o19:A 59 35 0.1477 0.2203 0.3714 3.2 6e33:A
19 2e0n:B 238 21 0.1023 0.0378 0.4286 4.2 2e0n:A
20 6gjc:A 2770 34 0.1250 0.0040 0.3235 4.6 6gjc:B, 6gjc:C, 6gjc:D, 6gjc:E, 6gjc:F
21 2qsw:A 90 26 0.1023 0.1000 0.3462 4.9
22 1qvr:A 803 32 0.1023 0.0112 0.2812 7.0 4fcv:A, 4fcv:B, 4fcv:C, 4fcw:A, 4fcw:C, 4fcw:F, 4fd2:A, 4fd2:B, 4fd2:D, 4lj5:A, 4lj6:A, 4lj7:A, 4lj7:B, 4lj7:C, 4lj8:A, 4lj9:A, 4lja:A, 1qvr:B, 1qvr:C
23 5m95:A 395 45 0.1591 0.0354 0.3111 8.4 5m95:C
24 6ph4:B 460 28 0.1023 0.0196 0.3214 9.9 5epv:A, 5epv:B, 5epv:C, 5epv:D, 6ph2:A, 6ph2:B, 6ph2:C, 6ph2:D, 6ph3:A, 6ph3:B, 6ph3:C, 6ph3:D, 6ph4:A, 6pps:A, 6pps:B, 6pps:C, 6pps:D, 3t50:A, 3t50:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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