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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SRRRTSLPAPSPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFA
ISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGT
THVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHR
LFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQK
QRIEQLQRERRRVLEENHVEHQPRFFRKSDGSWVSNGTYLELRKDLGFSKLDHPVLW

The query sequence (length=377) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7dei:B 377 377 1.0000 1.0000 1.0000 0.0 7dei:A
2 5zm8:A 386 378 0.4324 0.4223 0.4312 1.32e-91
3 5zm5:A 398 386 0.4271 0.4045 0.4171 4.22e-90 5zm6:A, 5zm6:B, 5zm7:A
4 5zm8:B 413 405 0.4324 0.3947 0.4025 2.58e-87
5 7v62:A 390 334 0.3926 0.3795 0.4431 1.03e-84 7v62:B, 7v62:C, 7v62:D
6 5h2d:A 418 380 0.3687 0.3325 0.3658 2.90e-74 5wvr:A
7 4inq:A 372 377 0.3740 0.3790 0.3740 2.17e-70
8 4ph7:D 407 355 0.2387 0.2211 0.2535 8.91e-18 4b2z:A, 4b2z:B, 4ph7:A, 4ph7:B, 4ph7:C
9 4jch:A 436 332 0.2095 0.1812 0.2380 3.32e-09 4f4b:A, 4f4b:B, 4fes:A, 4fes:B, 4jch:B, 1zht:A, 1zhw:A, 1zhx:A, 1zhy:A, 1zhz:A
10 3spw:A 398 76 0.0822 0.0779 0.4079 4.77e-05 3spw:B
11 6jsj:A 625 83 0.0531 0.0320 0.2410 0.37 6jsj:B, 6jsj:C
12 7xm9:A 1230 50 0.0531 0.0163 0.4000 2.3 6j8g:A, 6j8h:A, 6j8i:A, 6j8j:A, 7xmf:A, 7xmg:A, 8xmm:A
13 8xmn:A 1277 50 0.0531 0.0157 0.4000 2.3 8i5b:A, 8i5g:A, 8i5x:A, 8i5y:A, 8j4f:A, 8s9b:A, 8s9c:A, 8thg:A, 8thh:A, 7xve:A, 7xvf:A
14 8fl2:NB 81 29 0.0292 0.1358 0.3793 3.4 8fl3:NB, 8fl4:NB, 8ir1:u, 8ir3:u
15 7w9l:A 1420 50 0.0531 0.0141 0.4000 6.8 8g1a:A, 7w9k:A, 7w9m:A, 7w9p:A, 7w9t:A, 8xmo:A
16 1h1l:A 478 77 0.0690 0.0544 0.3377 7.5 1h1l:C, 1qgu:A, 1qgu:C, 1qh1:A, 1qh1:C, 1qh8:A, 1qh8:C
17 5v13:A 268 56 0.0398 0.0560 0.2679 8.9 5v13:B, 5v13:C
18 6rqx:A 862 157 0.1034 0.0452 0.2484 9.7 6m8p:A, 6m8p:B, 6m8p:C, 6m8p:D, 6m8p:E, 6m8p:F, 6m8p:G, 6m8p:H, 6m8p:I, 6m8p:J, 6m8p:K, 6m8p:L, 6m8p:M, 6m8p:N, 6m8p:O, 6m8p:P, 6m8p:Q, 6m8p:R, 6m8p:S, 6m8p:T, 6m8p:U, 6m8p:V, 3mdj:B, 6mgq:A, 6mgq:B, 6mgq:C, 6q4r:A, 3qnf:A, 3qnf:B, 3qnf:C, 6ryf:A, 6t6r:A, 2yd0:A, 7z28:A
19 6lmt:A 254 38 0.0371 0.0551 0.3684 9.9 6lmt:B, 6lmt:H, 6lmt:C, 6lmt:D, 6lmt:E, 6lmt:F, 6lmt:G

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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