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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SRRLLEETLAPFRLNHDQLAAVQAQMRKAMAKGLRGEASSLRMLPTFVRATPDGSERGDFLALDLGGTNFRVLLVRVTTG
VQITSEIYSIPETVAQGSGQQLFDHIVDCIVDFQQKQGLSGQSLPLGFTFSFPCRQLGLDQGILLNWTKGFKASDCEGQD
VVSLLREAITRRQAVELNVVAIVNDTVGTMMSCGYEDPRCEIGLIVGTGTNACYMEELRNVAGVPGDSGRMCINMEWGAF
GDDGSLAMLSTRFDASVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTSLGVLFRGQQIQRLQTRDIFKTKFLSEIES
DSLALRQVRAILEDLGLPLTSDDALMVLEVCQAVSQRAAQLCGAGVAAVVEKIRENRGLEELAVSVGVDGTLYKLHPRFS
SLVAATVRELAPRCVVTFLQSEDGSGKGAALVTAVACRLAQ

The query sequence (length=441) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3hm8:A 441 441 1.0000 1.0000 1.0000 0.0 3hm8:B, 3hm8:C, 3hm8:D
2 5hg1:A 867 444 0.6599 0.3356 0.6554 0.0
3 5hg1:A 867 443 0.5147 0.2618 0.5124 1.39e-149
4 5hfu:B 897 447 0.6599 0.3244 0.6510 0.0 5hex:A, 5hex:B, 5hfu:A, 2nzt:A
5 5hfu:B 897 443 0.5488 0.2698 0.5463 6.54e-171 5hex:A, 5hex:B, 5hfu:A, 2nzt:A
6 1qha:A 903 445 0.6440 0.3145 0.6382 0.0 1bg3:A, 1bg3:B, 1cza:N, 1dgk:N, 4f9o:A, 4f9o:B, 4foe:A, 4foe:B, 4foi:A, 4foi:B, 4fpa:A, 4fpa:B, 4fpb:A, 4fpb:B, 1hkb:A, 1hkb:B, 1hkc:A, 1qha:B
7 1qha:A 903 446 0.5238 0.2558 0.5179 4.07e-162 1bg3:A, 1bg3:B, 1cza:N, 1dgk:N, 4f9o:A, 4f9o:B, 4foe:A, 4foe:B, 4foi:A, 4foi:B, 4fpa:A, 4fpa:B, 4fpb:A, 4fpb:B, 1hkb:A, 1hkb:B, 1hkc:A, 1qha:B
8 2nzt:B 867 443 0.6417 0.3264 0.6388 0.0
9 2nzt:B 867 439 0.5465 0.2780 0.5490 3.91e-168
10 3idh:A 453 445 0.5306 0.5166 0.5258 9.68e-168 3a0i:X, 4dhy:A, 6e0e:A, 6e0i:A, 3f9m:A, 3fgu:A, 3fr0:A, 3goi:A, 3h1v:X, 3id8:A, 3imx:A, 4iwv:A, 4ixc:A, 4l3q:A, 4mle:A, 4mlh:A, 4no7:A, 3qic:A, 4rch:A, 3s41:A, 7t78:A, 7t78:B, 7t79:A, 7t79:B, 1v4s:A, 3vev:A, 3vey:A, 3vf6:A
11 4dch:A 434 446 0.4943 0.5023 0.4888 1.30e-149 4ise:A, 4isf:A, 4isg:A, 5v4w:A, 5v4x:A
12 1bdg:A 444 440 0.4467 0.4437 0.4477 6.48e-121
13 3o5b:A 479 451 0.3515 0.3236 0.3437 1.30e-83 3o5b:B, 3o80:A, 3o8m:A
14 6jj7:A 465 463 0.4014 0.3806 0.3823 2.45e-81 6jj7:C, 6jj7:E, 6jj8:C, 6jj8:A, 6jj8:B, 6jj9:C, 6jj9:A, 6jj9:E, 5zqt:A, 5zqt:B, 5zqt:C
15 3b8a:X 470 446 0.3469 0.3255 0.3430 2.75e-79
16 4qs7:A 455 439 0.3719 0.3604 0.3736 6.92e-75 4qs9:A
17 6pdt:A 500 462 0.3651 0.3220 0.3485 3.56e-71 6pdt:B, 6pdt:C, 6pdt:D
18 6ksr:A 467 468 0.3401 0.3212 0.3205 7.14e-58
19 7zzi:B 467 436 0.3084 0.2912 0.3119 2.44e-52 7zzi:A
20 2yhx:A 457 185 0.1020 0.0985 0.2432 6.70e-06
21 3ngj:D 222 107 0.0499 0.0991 0.2056 1.9 3ngj:A, 3ngj:B, 3ngj:C
22 2f02:A 319 64 0.0385 0.0533 0.2656 4.0 2f02:B
23 4fdg:B 592 61 0.0408 0.0304 0.2951 4.8 8eaf:A, 8eaf:B, 8eaf:C, 8eaf:D, 8eaf:E, 8eaf:F, 8eag:B, 8eag:C, 8eag:D, 8eag:E, 8eag:F, 8eag:A, 8eah:A, 8eah:B, 8eah:C, 8eah:D, 8eah:E, 8eah:F, 8eai:B, 8eai:C, 8eai:D, 8eai:E, 8eai:F, 8eai:A, 8eaj:A, 8eaj:B, 8eaj:C, 8eaj:D, 8eaj:E, 8eaj:F, 8eak:B, 8eak:C, 8eak:D, 8eak:E, 8eak:A, 8eak:F, 8eal:A, 8eal:B, 8eal:C, 8eal:D, 8eal:E, 8eal:F, 8eam:B, 8eam:C, 8eam:D, 8eam:E, 8eam:A, 8eam:F, 4fdg:A, 4fdg:C, 4fdg:D, 4fdg:E, 6mii:A, 6mii:B, 6mii:C, 6mii:D, 6mii:E, 6mii:F, 2vl6:A, 2vl6:B, 2vl6:C, 6wnz:B, 6wnz:A
24 5c37:A 632 123 0.0726 0.0506 0.2602 5.2 5c37:C, 6nna:A, 6nna:B, 4piv:A, 4piv:B
25 4r7y:A 591 61 0.0408 0.0305 0.2951 5.7 4r7y:B, 4r7z:A, 4r7z:B, 4r7z:C, 4r7z:D, 4r7z:E, 4r7z:F, 4r7z:G, 4r7z:H, 4r7z:I, 4r7z:P, 4r7z:J, 4r7z:K, 4r7z:L, 4r7z:M, 4r7z:N, 4r7z:O
26 8eyi:F 1211 123 0.0726 0.0264 0.2602 6.1 4w9n:A, 4w9n:B, 4w9n:C, 4w9n:D
27 8eyk:F 1070 123 0.0726 0.0299 0.2602 7.1
28 8eyk:E 966 123 0.0726 0.0331 0.2602 7.7 8eyi:E, 8gkc:A, 8gkc:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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