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●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
>protein
SRPQVTVHSLTGEATANALPLPAVFSAPIRPDIVHTVFTSVNKNKRQAYAVSEKAGHQTSAESWVARIPRVGGTGRSGQG
AFGNMCRGGRMFAPTKTWRKWNVKVNHNEKRYATASAIAATAVASLVLARGHRVEKIPEIPLVVSTDLESIQKTKEAVAA
LKAVGAHSDLLKVLKSKKLRAGKGKYRNRRWTQRRGPLVVYAEDNGIVKALRNVPGVETANVASLNLLQLAPGAHLGRFV
IWTEAAFTKLDQVWGSETVASSKVGYTLPSHIISTSDVTRIINSSEIQSAIRPAGQATQKRTHVLKKNPLKNKQVLLRLN
PYAKVFAAEKLGSKKA

The query sequence (length=336) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length 		Aligned
length 		Identity
(normalized by query) 		Identity
(normalized by hit) 		Identity (normalized
by aligned length) 		E-value Homologs
to hit
1 8aaf:l 361 343 1.0000 0.9307 0.9796 0.0 8agt:l, 8agu:l, 8agv:l, 8agw:l, 8agx:l, 8agz:l, 5apn:C, 5apo:C, 7azy:p, 7b7d:LF, 8bip:LC, 8bjq:LC, 8bn3:L4, 8bqd:BE, 8bqx:BE, 8ccs:GG, 8cdl:GG, 8cdr:GG, 8ceh:GG, 8cf5:GG, 8cg8:GG, 8cgn:GG, 8civ:GG, 8cku:GG, 8cmj:GG, 5dat:L4, 5dat:l4, 5dc3:L4, 5dc3:l4, 5dge:L4, 5dge:l4, 5dgf:L4, 5dgf:l4, 5dgv:L4, 5dgv:l4, 6elz:C, 6em1:C, 6em3:C, 6em4:C, 6em5:C, 8eub:AC, 8evp:AC, 8evq:AC, 8evr:AC, 8evs:AC, 8evt:AC, 8ewb:AC, 8ewc:AC, 5fci:L4, 5fci:l4, 5fcj:L4, 5fcj:l4, 6ft6:C, 5gak:G, 6gq1:C, 6gqb:C, 6gqv:C, 5h4p:C, 6hd7:G, 8hfr:DO, 6hhq:l, 6hhq:CF, 5i4l:L4, 5i4l:l4, 6i7o:BE, 6i7o:YE, 3j6x:L4, 3j6y:L4, 3j77:L4, 3j78:L4, 3jct:C, 5jcs:C, 5juo:H, 5jup:H, 5jus:H, 5jut:H, 5juu:H, 8k2d:LC, 8k82:LC, 5lyb:L4, 5lyb:l4, 5m1j:C5, 6m62:C, 5mc6:BE, 5mei:l, 5mei:CF, 7mpi:AC, 7mpj:AC, 6n8j:C, 6n8k:C, 6n8l:C, 6n8m:F, 6n8n:F, 6n8o:F, 7n8b:AC, 7nac:C, 5ndg:L4, 5ndg:l4, 5ndv:L4, 5ndv:l4, 5ndw:L4, 5ndw:l4, 7nrc:LF, 7nrd:LF, 5obm:L4, 5obm:l4, 7of1:C, 7oh3:C, 7ohq:C, 7ohr:C, 7ohs:C, 7ohu:C, 7ohv:C, 7ohw:C, 7ohx:C, 7ohy:C, 6oig:C, 5on6:l, 5on6:CF, 7osa:uL4, 7osm:uL4, 8p8m:LH, 8p8n:LH, 8p8u:LH, 8pfr:LH, 6q8y:BE, 6qik:D, 6qt0:D, 6qtz:D, 7r7a:C, 6r84:G, 6r86:G, 6r87:G, 6ri5:D, 7rr5:LC, 6rzz:D, 6s05:D, 6s47:AF, 6snt:j, 6sv4:BE, 6sv4:YE, 6sv4:ZE, 6t4q:LC, 5t62:F, 5t6r:F, 6t7i:LC, 6t7t:LC, 6t83:Cy, 6t83:Fa, 5tbw:l, 5tbw:CF, 6tb3:BE, 5tga:L4, 5tga:l4, 5tgm:L4, 5tgm:l4, 6tnu:BE, 7too:AL04, 7top:AL04, 7u0h:C, 4u3m:L4, 4u3m:l4, 4u3n:L4, 4u3n:l4, 4u3u:L4, 4u3u:l4, 4u4n:L4, 4u4n:l4, 4u4o:L4, 4u4o:l4, 4u4q:L4, 4u4q:l4, 4u4r:L4, 4u4r:l4, 4u4u:L4, 4u4u:l4, 4u4y:L4, 4u4y:l4, 4u4z:L4, 4u4z:l4, 4u50:L4, 4u50:l4, 4u51:L4, 4u51:l4, 4u52:L4, 4u52:l4, 4u53:L4, 4u53:l4, 4u55:L4, 4u55:l4, 4u56:L4, 4u56:l4, 4u6f:L4, 4u6f:l4, 7ug6:C, 7uoo:C, 7uqb:C, 7uqz:C, 7v08:C, 4v4b:BD, 4v7f:D, 4v7h:BD, 4v7r:BD, 4v7r:DD, 4v88:BC, 4v88:DC, 4v8t:C, 4v8y:BC, 4v8z:BC, 8v83:C, 8v84:C, 8v87:C, 4v91:C, 6woo:C, 6xiq:C, 6xir:C, 8y0u:LC, 6ylg:C, 6ylh:C, 6ylx:C, 6yly:C, 5z3g:G, 7z34:C, 6z6j:LC, 6z6k:LC, 7zpq:BC, 7zrs:BC, 7zs5:BE, 7zuw:BC, 7zux:EC, 7zw0:LG
2 7btb:C 336 336 0.9464 0.9464 0.9464 0.0 7bt6:C, 6c0f:C, 6cb1:C, 7ohp:C
3 4v6i:BD 329 343 0.9018 0.9210 0.8834 0.0
4 6uz7:AC 360 340 0.8750 0.8167 0.8647 0.0 5it7:CC
5 8c3a:l 361 342 0.7738 0.7202 0.7602 0.0 8c3a:AY, 8cq7:l, 8cq7:AY, 8cqw:l, 8cqw:AY, 8cre:l, 8cre:AY, 8oeq:l, 8oeq:AY, 7pzy:l, 7q08:l, 7q0f:l, 7q0p:l, 7q0r:l, 8q5i:l
6 8e5t:C 283 235 0.6994 0.8304 1.0000 2.30e-168
7 8e5t:C 283 40 0.1190 0.1413 1.0000 4.26e-19
8 8ev3:C 362 344 0.6815 0.6326 0.6657 3.69e-160 8esq:C, 8esr:C, 8etc:C, 8etg:C, 8eug:C, 8eui:C
9 7oya:C1 348 332 0.5923 0.5718 0.5994 1.02e-143 7oyb:C1
10 8euy:C 329 337 0.6131 0.6261 0.6113 8.97e-141 8eth:C, 8eti:C, 8etj:C, 8eup:C
11 7r81:F1 360 347 0.6429 0.6000 0.6225 3.69e-129
12 7olc:LC 363 350 0.6429 0.5950 0.6171 8.48e-129 8i9p:LC, 8i9r:LC, 8i9t:LC, 8i9v:LC, 8i9w:LC, 8i9x:LC, 8i9y:LC, 8i9z:LC, 8ia0:LC, 7old:LC, 8oo0:LC, 8pv1:LC, 8pv2:LC, 8pv3:LC, 8pv4:LC, 8pv5:LC, 8pv6:LC, 8pv7:LC, 8pv8:LC, 8pvk:LC, 8pvl:LC, 7z3n:LC, 7z3o:LC
13 7oyc:C1 351 332 0.5774 0.5527 0.5843 1.54e-128
14 7f5s:LC 368 334 0.5804 0.5299 0.5838 1.64e-128 7a01:t2, 8a3d:F, 5aj0:AC, 8b5l:C, 8b6c:C, 9bdl:AL04, 9bdn:AL04, 9bdp:AL04, 7bhp:LC, 8bhf:l3, 8bpo:C2, 8btk:BC, 7cpu:LC, 7cpv:LC, 4d5y:C, 4d67:C, 6d90:C, 6d9j:C, 9f1b:BC, 9f1c:BC, 9f1d:BC, 8fkt:SA, 8fku:SA, 8fkv:SA, 8fkw:SA, 8fkx:SA, 8fky:SA, 8fkz:SA, 8fl2:SA, 8fl3:SA, 8fl4:SA, 8fl6:SA, 8fl7:SA, 8fl9:SA, 8fla:SA, 8flb:SA, 8flc:SA, 8fld:SA, 8fle:SA, 8flf:SA, 9fpz:LC, 9fq0:LC, 6frk:C, 6ftg:C, 6fti:C, 6ftj:C, 8g5y:LC, 8g5z:LC, 8g60:LC, 8g61:LC, 8g6j:LC, 8glp:LC, 6gz3:AC, 6gz4:AC, 6gz5:AC, 6hcf:C3, 6hcj:C3, 6hcm:C3, 6hcq:C3, 8idt:D, 8idy:D, 8ie3:D, 8ifd:1F, 8ife:1F, 8ine:D, 8inf:D, 8ink:D, 6ip5:1F, 6ip6:1F, 6ip8:1F, 8ipd:D, 8ipx:D, 8ipy:D, 8ir1:D, 8ir3:D, 3j7o:C, 3j7p:C, 3j7q:C, 3j7r:C, 3j92:C, 3jag:C, 3jah:C, 3jai:C, 3jaj:C, 3jan:C, 8jdj:I, 8jdk:I, 8jdl:I, 8jdm:I, 8k2c:LC, 5lks:LC, 6lqm:D, 6lsr:D, 6lss:D, 7ls1:F2, 7ls2:F2, 6lu8:D, 5lzs:C, 5lzt:C, 5lzu:C, 5lzv:C, 5lzw:C, 5lzx:C, 5lzy:C, 5lzz:C, 7mdz:C, 6mtb:C, 6mtc:C, 6mtd:C, 6mte:C, 7nfx:C, 7nwg:C3, 7nwh:C, 7nwi:C, 7o7y:BC, 7o7z:BC, 7o80:BC, 7o81:BC, 7obr:C, 8ohd:LC, 8oj0:LC, 8oj5:LC, 8oj8:LC, 6ole:C, 6olf:C, 6olg:AC, 6oli:C, 6olz:AC, 6om0:C, 6om7:C, 7ow7:F, 7oyd:C, 8p2k:BC, 6p5i:AC, 6p5j:AC, 6p5k:AC, 6p5n:AC, 8q7z:BC, 8q87:BC, 8qfd:C, 7qgg:C, 8qoi:LC, 7qvp:MC, 7qvp:LC, 7qwq:C, 7qwr:C, 7qws:C, 6qzp:LC, 6r5q:C, 6r6g:C, 6r6p:C, 6r7q:C, 8rjb:C, 8rjc:C, 8rjd:C, 8scb:C, 6sgc:C2, 6swa:C, 5t2c:F, 6t59:C3, 7tm3:C, 7toq:AL04, 7tor:AL04, 7tut:C, 7ucj:C, 7uck:C, 4ug0:LC, 4ujc:BC, 4ujd:AC, 4uje:CC, 4v5z:Bc, 4v6x:CC, 6w6l:C, 6xa1:LC, 7xnx:LC, 7xny:LC, 8xsx:LC, 8xsy:LC, 8xsz:LC, 6y0g:LC, 8y0w:LC, 8y0x:LC, 6y2l:LC, 6y57:LC, 6y6x:LC, 8yoo:LC, 8yop:LC, 6z6l:LC, 6z6m:LC, 6z6n:LC, 7zjw:LF, 7zjx:LF, 6zm7:LC, 6zme:LC, 6zmi:LC, 6zmo:LC, 6zvk:t2
15 8jiv:CC 376 333 0.5714 0.5106 0.5766 2.97e-127
16 8azw:s 398 332 0.5923 0.5000 0.5994 2.85e-121 8b2l:s3, 7qiw:F, 7qiz:F
17 8ip8:EB 399 333 0.5565 0.4687 0.5616 5.23e-118 8ipa:EB, 8ipb:EB
18 4v8p:BC 409 340 0.5506 0.4523 0.5441 4.90e-117 4v8p:CC, 4v8p:EC, 4v8p:GC
19 3j79:F 390 332 0.5000 0.4308 0.5060 8.73e-116 3jbn:AF, 3jbo:AF, 3jbp:AF, 8tpu:AF, 5umd:F
20 7oht:C 239 235 0.5952 0.8368 0.8511 1.29e-115
21 7oht:C 239 26 0.0685 0.0962 0.8846 6.85e-08
22 9bh5:CC 335 334 0.5149 0.5164 0.5180 4.71e-115 9cai:CC
23 4v6w:CC 392 345 0.5446 0.4668 0.5304 5.43e-115 6xu6:CC, 6xu7:CC, 6xu8:CC
24 4v3p:LD 372 333 0.5327 0.4812 0.5375 2.49e-113 4v7e:CC
25 5xxb:C 394 334 0.5327 0.4543 0.5359 1.27e-112
26 8fkp:SA 331 327 0.5179 0.5257 0.5321 3.83e-112 8fkq:SA, 8fkr:SA, 8fks:SA
27 8a98:C 366 332 0.4970 0.4563 0.5030 2.26e-111 8a3w:C, 6az3:C, 3jcs:C, 8ovj:C, 8rxh:LC, 8rxx:LC, 5t2a:p, 5t5h:r
28 8ova:Br 367 300 0.4524 0.4142 0.5067 1.09e-107 8ove:Br, 4v8m:Br
29 6zj3:LR 365 332 0.4851 0.4466 0.4910 2.03e-93
30 6zu5:LC0 325 330 0.4286 0.4431 0.4364 1.59e-84
31 8p5d:LC0 327 324 0.4137 0.4251 0.4290 2.38e-83 8p60:LC0, 8p60:KC0, 7qca:LC0
32 8btd:LC 315 332 0.4405 0.4698 0.4458 5.13e-81 8br8:LC, 8brm:LC, 8bsi:LC, 8bsj:LC, 8btr:LC, 8fru:C, 7pwg:C, 7pwo:C2
33 7qep:L4 329 298 0.4018 0.4103 0.4530 5.18e-81
34 6rm3:LC0 329 338 0.3929 0.4012 0.3905 1.41e-72
35 5xy3:C 362 293 0.3720 0.3453 0.4266 3.40e-66
36 8fl0:SA 274 224 0.3214 0.3942 0.4821 1.70e-65
37 8fl0:SA 274 43 0.0655 0.0803 0.5116 7.18e-07
38 6skf:BE 255 257 0.2917 0.3843 0.3813 5.81e-49 6skg:BE, 6th6:BE
39 4v4n:AD 255 257 0.2798 0.3686 0.3658 1.32e-47 4v6u:BD
40 8hku:AL4P 251 255 0.2798 0.3745 0.3686 5.86e-45 8hkv:AL4P, 8hky:AL4P, 8hkz:AL4P, 8hl1:AL4P, 8hl2:AL4P, 8hl3:AL4P, 8hl4:AL4P, 8hl5:AL4P
41 3cc2:C 246 252 0.2530 0.3455 0.3373 1.40e-34 3cc4:C, 3cc7:C, 3cce:C, 3ccj:C, 3ccl:C, 3ccm:C, 3ccq:C, 3ccr:C, 3ccs:C, 3ccu:C, 3ccv:C, 3cd6:C, 3cma:C, 3cme:C, 3cpw:C, 3cxc:C, 1ffk:C, 3g4s:C, 3g6e:C, 3g71:C, 3i55:C, 3i56:C, 1jj2:C, 1k73:E, 1k8a:E, 1k9m:E, 1kc8:E, 1kd1:E, 1kqs:C, 1m1k:E, 1m90:E, 1n8r:E, 1nji:E, 2otj:C, 2otl:C, 3ow2:C, 1q7y:E, 1q81:E, 1q82:E, 1q86:E, 2qa4:C, 2qex:C, 1qvf:C, 1qvg:C, 1s72:C, 4v9f:C, 1vq4:C, 1vq5:C, 1vq6:C, 1vq7:C, 1vq8:C, 1vq9:C, 1vqk:C, 1vql:C, 1vqm:C, 1vqn:C, 1vqo:C, 1vqp:C, 1w2b:C, 1yhq:C, 1yi2:C, 1yij:C, 1yit:C, 1yj9:C, 1yjn:C, 1yjw:C
42 4v4p:AF 189 236 0.1964 0.3492 0.2797 2.35e-19 4v4r:BF, 4v4s:BF, 4v4t:BF
43 6eri:AE 212 141 0.1190 0.1887 0.2837 0.001 5h1s:G, 5mlc:F, 5mmi:E, 5mmm:E, 4v61:BG, 5x8p:E, 5x8t:E
44 6xyw:Ad 209 111 0.1012 0.1627 0.3063 0.049
45 7asm:E 206 58 0.0565 0.0922 0.3276 0.21 7asn:E, 7aso:J, 7asp:E, 6ddd:S, 6ddg:S, 6fxc:AE, 6fxc:BE, 5hkv:C, 5hl7:C, 6hma:E, 5li0:F, 5nd8:F, 5nd9:F, 5ngm:AE, 7nhl:I, 7nhm:I, 5nrg:C, 8p2f:I, 8p2g:I, 8p2h:I, 7p48:E, 6s0x:E, 6s0z:E, 6s12:E, 6s13:E, 6sj6:F, 5t7v:LJ, 5tcu:LJ, 7ttu:S, 7ttw:S, 4wce:C, 4wf9:C, 4wfa:C, 4wfb:C, 6wqn:S, 6wqq:S, 6wrs:S, 6wru:S, 8y36:E, 8y37:E, 8y38:E, 8y39:E, 6yef:F
46 8a22:Ac 303 104 0.1071 0.1188 0.3462 0.26 8apn:Ac, 8apo:Ac
47 7ofv:A 184 75 0.0565 0.1033 0.2533 0.33 5jr2:A, 5jr2:B, 5jr2:C, 5jr2:D, 4w4z:A, 4w4z:B, 4w4z:C, 4w4z:D, 4w50:A, 4w50:B, 4w50:C, 4w50:D, 2wo1:A, 2wo1:B
48 8buu:E 206 188 0.1339 0.2184 0.2394 0.85 7aqc:E, 7aqd:E, 7as8:G, 7as9:G, 6ha1:E, 6ha8:E, 6htq:E, 3j3v:E, 3j3w:E, 3j9w:BF, 5njt:Y, 7o5b:b, 7ope:G, 6ppf:E, 6ppk:E, 6pvk:E, 8qcq:E, 7qgu:E, 7qh4:E, 8qpp:b, 7qv1:E, 7qv2:E, 7qv3:E, 8r55:b, 8s1p:E, 8s1u:E, 7s9u:E, 7sae:E, 6tnn:Y, 6tpq:Y
49 3m5p:A 542 42 0.0417 0.0258 0.3333 5.1 3q7i:A, 3q88:A
50 5hxf:A 182 32 0.0327 0.0604 0.3438 9.3 5c1u:A, 5c1u:B, 5c1x:A, 5c1x:B, 5c1y:A, 5c20:A, 7dnc:A, 5dp3:A, 5dp4:A, 5dp4:B, 5dp4:C, 5dp4:D, 5dp5:A, 5dp6:A, 5dp6:B, 5dp7:A, 5dp8:A, 5dp9:A, 5dpa:A, 4ght:A, 4ght:B, 5gso:A, 5gso:B, 5gso:C, 5gso:D, 5gso:E, 5gsw:A, 5gsw:B, 5gsw:C, 5gsw:D, 5gsw:E, 6lka:A, 7qub:AAA, 3qzq:A, 3qzq:B, 3qzq:C, 3qzq:D, 3qzr:A, 3qzr:B, 3r0f:A, 3r0f:B, 3sj9:A, 3sji:A, 3sjk:A, 3sjo:A, 3sjo:B, 3sjo:C, 3sjo:D, 3sjo:E, 3sjo:F, 3sjo:G, 3sjo:H, 5wq2:A, 7wyl:A, 7wyo:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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