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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SRPQSTLRRAITAAYRRPETECLPPLVEAATQSKEIRDAAASTARKLIEALRGKGSMMGEQFVTGETIREALKRSKELEE
KGFSYSYDMLGEAATTAADAERYYRDYESAIHAIGKASAGRGIYEGPGISIKLSALHPRYSRAQAARVMGELLPRVKALA
LLAKNYDIGLNIDAEEADRLELSLDLLEVLCLDGDLSGWNGMGFVVQAYGKRCPFVLDFIIDLARRSGRRIMVRLVKGAY
WDAEIKRAQLDGLADFPVFTRKIHTDVSYIACAAKLLAATDVVFPQFATHNAQTLAAIYHMAGKDFHVGKYEFQCLHGMG
EPLYEEVVGRGKLDRPCRIYAPVGTHETLLAYLVRRLLENGANSSFVHRINDPKVSIDELIADPVEVVRAMPV

The query sequence (length=393) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8dko:B 393 393 1.0000 1.0000 1.0000 0.0 8dko:A, 8dkp:A, 8dkp:B, 8dkq:B, 8w0k:B
2 6x9d:A 1218 337 0.8575 0.2767 1.0000 0.0 8dkq:A, 5kf6:A, 5kf6:B, 5kf7:A, 7my9:A, 7my9:B, 7mya:A, 7mya:B, 7myb:A, 7myb:B, 7myc:A, 7myc:B, 6ufp:A, 6ufp:B, 6vz9:A, 6vz9:B, 8w0k:A, 6x99:A, 6x99:B, 6x9a:A, 6x9a:B, 6x9b:A, 6x9b:B, 6x9c:A, 6x9c:B, 6x9d:B
3 6x9d:A 1218 65 0.1425 0.0460 0.8615 2.19e-25 8dkq:A, 5kf6:A, 5kf6:B, 5kf7:A, 7my9:A, 7my9:B, 7mya:A, 7mya:B, 7myb:A, 7myb:B, 7myc:A, 7myc:B, 6ufp:A, 6ufp:B, 6vz9:A, 6vz9:B, 8w0k:A, 6x99:A, 6x99:B, 6x9a:A, 6x9a:B, 6x9b:A, 6x9b:B, 6x9c:A, 6x9c:B, 6x9d:B
4 2fzn:A 449 430 0.6845 0.5991 0.6256 0.0
5 3itg:A 399 392 0.6667 0.6566 0.6684 0.0
6 1tj0:A 469 450 0.6870 0.5757 0.6000 0.0 3e2q:A, 3e2r:A, 3e2s:A, 2fzm:A, 4o8a:A, 1tiw:A, 1tj1:A, 1tj2:A
7 7sqn:A 503 338 0.6260 0.4891 0.7278 0.0 3itg:B, 4jny:A, 4jnz:A, 7mwt:A, 7mwu:A, 7mwv:A
8 7sqn:A 503 74 0.0687 0.0537 0.3649 3.09e-04 3itg:B, 4jny:A, 4jnz:A, 7mwt:A, 7mwu:A, 7mwv:A
9 3haz:A 983 339 0.4631 0.1851 0.5369 1.17e-111 6bsn:A, 6bsn:B, 3haz:B, 4q71:A, 4q71:B, 4q72:A, 4q72:B, 4q73:A, 4q73:B
10 5ur2:B 959 343 0.2799 0.1147 0.3207 2.56e-41 5ur2:A, 5ur2:C, 5ur2:D
11 7na0:A 981 389 0.2977 0.1193 0.3008 7.30e-36 7na0:B, 4nm9:A, 4nm9:B, 4nma:A, 4nma:B, 4nmb:A, 4nmb:B, 4nmc:B, 4nmd:A, 4nmd:B, 4nme:A, 4nme:B, 4nmf:A, 4nmf:B
12 4nmc:A 941 321 0.2545 0.1063 0.3115 3.19e-28
13 4h6q:A 281 316 0.2188 0.3060 0.2722 5.63e-13 4h6q:C, 4h6r:A, 4h6r:C
14 2g37:B 300 310 0.2188 0.2867 0.2774 2.23e-10 2ekg:A, 2ekg:B, 2g37:A, 5m42:A
15 5ux5:A 963 166 0.1221 0.0498 0.2892 0.009 5ux5:B, 5ux5:C, 5ux5:D
16 8wil:A 574 53 0.0509 0.0348 0.3774 0.90 8wim:A
17 3tkn:A 451 77 0.0585 0.0510 0.2987 4.3 3pbp:A, 3pbp:D, 3pbp:G, 3pbp:J, 3tkn:G, 3tkn:D
18 2bzf:A 88 78 0.0560 0.2500 0.2821 4.6
19 8hmo:A 205 45 0.0356 0.0683 0.3111 5.1 8hmo:B, 8hmo:C, 8hmo:D, 8hmo:E, 8hmo:F
20 1iwa:A 473 52 0.0356 0.0296 0.2692 6.1 1bwv:A, 1bwv:C, 1bwv:E, 1bwv:G, 4f0h:A, 1iwa:C, 1iwa:E, 1iwa:I, 1iwa:K, 1iwa:M, 1iwa:O
21 2pmq:B 374 39 0.0382 0.0401 0.3846 6.5 4h2h:A, 4h2h:B, 4h2h:C, 4h2h:D, 4h2h:E, 4h2h:F, 4h2h:G, 4h2h:H, 2pmq:A
22 3jrx:A 496 80 0.0509 0.0403 0.2500 7.7 5kkn:B, 5kkn:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218