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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SRFKVSKLMAYILRHSPWEFGLEPDEEGFVSIEELVNAVRKVYPWVTEEYIREIVERDEKGRYEIRGNKIRARYGHSYPV
ILRHEEDKESKVLYHGTVRRNLKGIMREGIKPMKRQYVHLSINYEDAYNTGMRHGEDVVVLIIDAECLRNKGYKILKAGK
KVRIVKHVPVDCISGIL

The query sequence (length=177) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8tfx:A 177 177 1.0000 1.0000 1.0000 2.65e-128 8tfy:A, 8tfz:A, 8tfz:B, 8tg5:A, 8tkb:A
2 8tg3:A 187 174 0.4294 0.4064 0.4368 2.99e-43 8tg4:A
3 6e3a:A 180 168 0.4011 0.3944 0.4226 4.67e-39 6ede:A
4 7kw9:A 178 172 0.3559 0.3539 0.3663 3.53e-32
5 7yw3:A 205 171 0.2429 0.2098 0.2515 4.33e-10
6 7yw2:A 206 152 0.2316 0.1990 0.2697 1.79e-08
7 7yw4:A 120 94 0.1469 0.2167 0.2766 0.001
8 2v45:A 723 21 0.0621 0.0152 0.5238 2.0 2jim:A, 2jio:A, 2jip:A, 2jiq:A, 2jir:A, 2nap:A, 2v3v:A
9 5fra:A 197 45 0.0791 0.0711 0.3111 2.4 5fra:B, 5fra:C, 5fra:D, 5fra:E, 5fra:F, 5fre:A, 5fre:B, 5fre:C
10 4v61:BN 176 84 0.1299 0.1307 0.2738 2.8
11 2k60:A 150 56 0.0904 0.1067 0.2857 3.4
12 4pbq:A 304 66 0.0904 0.0526 0.2424 3.8 4pbq:B, 4pbq:C
13 1ncy:A 162 34 0.0734 0.0802 0.3824 4.4 1a2x:A, 1avs:A, 1avs:B, 1cta:A, 1cta:B, 1ctd:A, 1ctd:B, 1jc2:A, 1npq:A, 1smg:A, 1tnq:A, 4tnc:A, 5tnc:A, 1top:A, 2w49:0, 2w49:3, 2w49:6, 2w49:9, 1ytz:C, 1yv0:C
14 4hn1:C 201 66 0.1017 0.0896 0.2727 4.6 4hmz:A, 4hmz:B, 4hmz:C, 4hmz:D, 4hn1:A, 4hn1:B, 4hn1:D
15 2l1w:A 149 37 0.0678 0.0805 0.3243 7.9 2ksz:A, 2roa:A, 2rob:A
16 1wir:A 121 33 0.0452 0.0661 0.2424 8.1
17 6yl2:B 192 48 0.1073 0.0990 0.3958 8.4 6yl2:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218