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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SREVLAEKVKNAVNNQPVTDMHTHLFSPNFGEILLWDIDELLTYHYLVAEVMRWTDVSIEAFWAMSKREQADLIWEELFI
KRSPVSEACRGVLTCLQGLGLDPATRDLQVYREYFAKKTSEEQVDTVLQLANVSDVVMTNDPFDDNERISWLEGKQPDSR
FHAALRLDPLLNEYEQTKHRLRDWGYKVNDEWNEGSIQEVKRFLTDWIERMDPVYMAVSLPPTFSFPEESNRGRIIRDCL
LPVAEKHNIPFAMMIGVKKRVHPALGDAGDFVGKASMDGVEHLLREYPNNKFLVTMLSRENQHELVVLARKFSNLMIFGC
WWFMNNPEIINEMTRMRMEMLGTSFIPQHSDARVLEQLIYKWHHSKSIIAEVLIDKYDDILQAGWEVTEEEIKRDVADLF
SRNFWRFVGR

The query sequence (length=410) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2qee:E 424 410 1.0000 0.9670 1.0000 0.0 3hk5:A, 3hk5:B, 3hk7:A, 3hk7:B, 3hk7:C, 3hk7:D, 3hk7:F, 3hk7:E, 3hk7:G, 3hk7:I, 3hk7:H, 3hk7:J, 3hk7:L, 3hk7:K, 3hk8:A, 3hk8:B, 3hk9:A, 3hk9:B, 3hk9:C, 3hk9:D, 3hk9:E, 3hk9:F, 3hk9:G, 3hk9:I, 3hk9:H, 3hk9:J, 3hk9:L, 3hk9:K, 3hka:A, 3hka:C, 3hka:B, 2q08:A, 2q08:B, 2q08:C, 2q08:D, 2q08:E, 2q08:F, 2q08:G, 2q08:H, 2q08:I, 2q08:J, 2q08:K, 2q08:L, 2q6e:A, 2q6e:B, 2q6e:C, 2qee:A, 2qee:B, 2qee:C, 2qee:D, 2qee:F, 2qee:G, 2qee:H, 2qee:I, 2qee:J, 2qee:K, 2qee:L
2 4i6v:B 430 279 0.1780 0.1698 0.2616 3.34e-12 4i6v:A, 4i6v:C
3 7rnu:C 110 52 0.0463 0.1727 0.3654 0.64 7rnu:A, 7rnu:E, 7rnu:G
4 7mtl:A 168 56 0.0415 0.1012 0.3036 0.74 7mtl:B
5 2z72:A 338 28 0.0293 0.0355 0.4286 2.5 1v73:A, 2zbm:A
6 6skf:Aw 95 39 0.0366 0.1579 0.3846 3.3 6skg:Aw, 6skg:Bn, 6th6:Aw
7 4iwx:A 294 97 0.0707 0.0986 0.2990 4.0 4iwy:A, 5zct:A, 5zct:B, 5zct:C, 5zct:D, 5zct:E, 5zct:F, 5zct:G, 5zct:H, 5zk6:A
8 3aov:A 404 62 0.0512 0.0520 0.3387 5.5 3aov:C, 3aow:A, 3aow:C, 3ath:A, 3ath:C, 3av7:A, 3av7:C, 3wx9:A, 3wx9:C
9 5bof:A 434 39 0.0341 0.0323 0.3590 5.7 5boe:A, 5boe:B, 5bof:B
10 3was:A 389 85 0.0537 0.0566 0.2588 8.7 4kmi:A, 4kmi:B, 3was:B, 3wat:A, 3wat:B, 3wau:A, 3wau:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218