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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SQTIDKINSCYPLFEQDEYQELFRNKRQLEEAHDAQRVQEVFAWTTTAEYEALNFRREALTVDPAKACQPLGAVLCSLGF
ANTLPYVHGSQGCVAYFRTYFNRHFKEPIACVSDSMTEDAAVFGGNNNMNLGLQNASALYKPEIIAVSTTCMAEVIGDDL
QAFIANAKKDGFVDSSIAVPHAHTPSFIGSHVTGWDNMFEGFAKTFTADYQGQPGKLPKLNLVTGFETYLGNFRVLKRMM
EQMAVPCSLLSDPSEVLDTPADGHYRMYSGGTTQQEMKEAPDAIDTLLLQPWQLLKSKKVVQEMWNQPATEVAIPLGLAA
TDELLMTVSQLSGKPIADALTLERGRLVDMMLDSHTWLHGKKFGLYGDPDFVMGLTRFLLELGCEPTVILSHNANKRWQK
AMNKMLDASPYGRDSEVFINCDLWHFRSLMFTRQPDFMIGNSYGKFIQRDTLAKGKAFEVPLIRLGFPLFDRHHLHRQTT
WGYEGAMNIVTTLVNAVLEKLDSDTSQLGKTDYSFDLVR

The query sequence (length=519) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1h1l:B 519 519 1.0000 1.0000 1.0000 0.0 1h1l:D, 1qgu:B, 1qgu:D, 1qh1:B, 1qh1:D, 1qh8:B, 1qh8:D
2 2afh:B 522 522 0.6782 0.6743 0.6743 0.0 2afh:D, 2afi:B, 2afi:D, 2afi:J, 2afi:L, 6bbl:B, 6bbl:D, 8bts:B, 8bts:D, 8bts:I, 8bts:L, 5bvg:B, 5bvg:D, 5bvh:B, 5bvh:D, 6cdk:B, 6cdk:D, 8crs:D, 8crs:B, 5cx1:B, 5cx1:D, 5cx1:F, 5cx1:H, 5cx1:J, 5cx1:L, 5cx1:N, 5cx1:P, 8dbx:B, 8dbx:D, 8dby:B, 8dby:D, 8dfc:B, 8dfc:D, 8dfd:B, 8dfd:D, 8dpn:B, 8dpn:D, 8e3t:B, 8e3t:D, 8e3u:B, 8e3u:D, 8e3v:B, 8e3v:D, 8enl:B, 8enl:D, 8enm:B, 8enm:D, 8enn:B, 8enn:D, 8eno:B, 8eno:D, 1fp4:B, 1fp4:D, 1g20:B, 1g20:D, 1g21:B, 1g21:D, 7jrf:B, 7jrf:D, 3k1a:B, 3k1a:D, 1l5h:B, 1m1n:B, 1m1n:D, 1m1n:F, 1m1n:H, 1m1y:B, 1m1y:D, 1m1y:J, 1m1y:L, 1m34:B, 1m34:D, 1m34:J, 1m34:L, 7mci:B, 7mci:D, 2min:B, 2min:D, 3min:B, 3min:D, 1n2c:B, 1n2c:D, 4nd8:B, 4nd8:D, 6o7l:B, 6o7l:D, 6o7m:B, 6o7m:D, 6o7n:B, 6o7n:D, 6o7o:B, 6o7o:D, 6o7p:B, 6o7p:D, 6o7q:B, 6o7q:D, 6o7r:B, 6o7r:D, 6o7s:B, 6o7s:D, 6op1:B, 6op1:D, 6op2:B, 6op2:D, 6op3:B, 6op3:D, 6op4:B, 6op4:D, 8p8g:B, 8p8g:D, 4tku:B, 4tku:D, 4tkv:B, 4tkv:D, 3u7q:B, 3u7q:D, 6ug0:B, 6ug0:D, 7ut6:B, 7ut6:D, 7ut7:B, 7ut7:D, 7ut8:B, 7ut8:D, 7ut9:B, 7ut9:D, 7uta:B, 7uta:D, 5vq4:B, 5vq4:D, 6vxt:B, 6vxt:D, 4wna:B, 4wna:D, 4wza:B, 4wza:D, 4wzb:B, 4wzb:D, 4xpi:B, 4xpi:D
3 5koh:B 510 519 0.5067 0.5157 0.5067 0.0 5koh:D, 5koj:B, 5koj:D
4 5vpw:B 458 465 0.3276 0.3712 0.3656 2.49e-112 1mio:B, 1mio:D, 5vpw:D, 5vq3:B, 5vq3:D, 4wes:B, 4wes:D, 4wn9:B, 4wn9:D
5 7adr:E 466 457 0.2813 0.3133 0.3195 6.12e-72 7adr:B, 7ady:B, 7ady:E, 7aiz:B, 7aiz:E, 6fea:B, 6fea:E, 5n6y:B, 5n6y:E
6 8oie:C 456 455 0.2659 0.3026 0.3033 1.74e-71 8oie:H, 8pbb:B, 8pbb:D
7 8boq:B 461 462 0.2678 0.3015 0.3009 1.10e-66 8boq:E
8 3pdi:B 432 447 0.2331 0.2801 0.2707 9.17e-48 3pdi:D, 3pdi:F, 3pdi:H
9 3aer:D 421 451 0.1773 0.2185 0.2040 3.24e-09 3aek:B, 3aek:D, 3aeq:B, 3aeq:D, 3aer:B, 3aes:B, 3aes:D, 3aet:B, 3aet:D, 3aeu:D
10 1mio:A 525 117 0.0674 0.0667 0.2991 7.27e-06 1mio:C, 5vpw:A, 5vq3:A, 5vq3:C, 4wes:A, 4wes:C, 4wn9:A, 4wn9:C
11 5vpw:C 495 117 0.0674 0.0707 0.2991 7.30e-06
12 2ynm:D 488 390 0.1580 0.1680 0.2103 1.62e-04
13 7adr:A 473 162 0.0906 0.0994 0.2901 2.81e-04 7adr:D, 7ady:A, 7ady:D, 7aiz:A, 7aiz:D, 6fea:A, 6fea:D, 5n6y:A, 5n6y:D
14 3pdi:A 427 137 0.0655 0.0796 0.2482 0.31 3pdi:C, 3pdi:E, 3pdi:G
15 1h1l:A 478 134 0.0597 0.0649 0.2313 0.66 1h1l:C, 1qgu:A, 1qgu:C, 1qh1:A, 1qh1:C, 1qh8:A, 1qh8:C
16 5of3:C 107 53 0.0270 0.1308 0.2642 0.85 5of3:F
17 7z1i:A 493 78 0.0482 0.0507 0.3205 1.6 7z1i:B, 7z1i:D
18 8x2h:A 2363 73 0.0424 0.0093 0.3014 2.5 8jb5:A, 2vkd:A, 2vkd:B, 2vkd:C, 2vkh:A, 2vkh:B, 2vkh:C, 2vl8:A, 2vl8:B, 2vl8:C
19 8x2i:A 2303 73 0.0424 0.0096 0.3014 2.6
20 8sk0:B 330 37 0.0289 0.0455 0.4054 3.0 8shh:A, 8shh:B, 8sk0:A
21 2hci:A 68 47 0.0270 0.2059 0.2979 3.5
22 9bdd:A 212 82 0.0424 0.1038 0.2683 4.0 9bdc:B, 9bdc:A, 9bdd:B, 5ola:A, 5ola:C, 8u8u:A, 8u8u:B, 8u8v:B, 8u8v:A
23 5dsg:B 399 66 0.0424 0.0551 0.3333 4.8 5dsg:A
24 6vyx:AA 1223 258 0.1098 0.0466 0.2209 6.0 6vyy:AA, 6vyz:AA, 6vz3:AA
25 7v68:R 277 66 0.0424 0.0794 0.3333 7.8 8e9x:A, 8fx5:R, 7trk:R, 7trp:R, 7trq:R, 7trs:R, 7v6a:R
26 2epn:A 623 79 0.0385 0.0321 0.2532 8.6 2epn:B
27 8ki7:A 2003 112 0.0578 0.0150 0.2679 10.0

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218