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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SQSIFDILSAEEIHLIEASVEQFGAPLLLLDCDVIRQQYRALKNALPNVTLHYALKPLPHPVVVRTLLAEGASFDLATTG
EVELVASEGVPADLTIHTHPIKRDADIRDALAYGCNVFVVDNLNELEKFKAYRDDVELLVRLSFKKFGCSPEQALVIIET
AKEWNIRIKGLSFHVGSQTTNPNKYVEAIHTCRHVMEQVVERGLPALSTLDIGGGFPVNYTQQVMPIDQFCAPINEALSL
LPETVHVLAEPGRFICAPAVTSVASVMGQAEREGQIWYYLDDGIYGSFSGLMFDDARYPLTTIKQGGELIPSVLSGPTCD
SVDVIAENILLPKLNNGDLVIGRTMGAYTSATATDFNFFKRAQTIALNEF

The query sequence (length=370) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2plj:A 376 374 1.0000 0.9840 0.9893 0.0 2plj:B, 2plk:A, 2plk:B
2 5gjo:A 385 374 0.3459 0.3325 0.3422 5.00e-69 5gjn:A, 5gjo:B, 5gjp:A
3 2oo0:A 419 347 0.3432 0.3031 0.3660 2.54e-57 5bwa:A, 7odc:A, 2on3:A, 2on3:B, 2oo0:B, 7s3f:A, 7s3f:B, 7s3g:A, 7s3g:B, 7u6p:A, 7u6p:B, 7u6u:A, 7u6u:B, 4zgy:A
4 1f3t:B 381 350 0.3270 0.3176 0.3457 1.82e-55 1f3t:A, 1f3t:C, 1f3t:D, 1njj:A, 1njj:B, 1njj:C, 1njj:D, 1qu4:A, 1qu4:B, 1qu4:C, 1qu4:D, 1szr:C, 1szr:D, 1szr:A, 1szr:B, 2tod:A, 2tod:B, 2tod:C, 2tod:D
5 2nv9:B 372 330 0.2892 0.2876 0.3242 1.10e-47 2nv9:A, 2nv9:C, 2nv9:D, 2nv9:E, 2nv9:F, 2nv9:G, 2nv9:H, 2nva:A, 2nva:B, 2nva:C, 2nva:D, 2nva:E, 2nva:F, 2nva:G, 2nva:H
6 2yxx:A 385 374 0.2486 0.2390 0.2460 1.08e-26
7 1hkv:A 446 395 0.2541 0.2108 0.2380 2.07e-22 1hkv:B
8 7ru7:A 412 366 0.2135 0.1917 0.2158 1.47e-19 2j66:A
9 4xg1:A 393 370 0.2541 0.2392 0.2541 2.21e-19
10 4xg1:B 418 388 0.2541 0.2249 0.2423 2.28e-19 4xg1:C, 4xg1:D
11 3c5q:A 394 368 0.2297 0.2157 0.2310 7.21e-18 2qgh:A
12 7kh2:D 415 392 0.2108 0.1880 0.1990 7.48e-17 7kh2:A, 7kh2:B, 7kh2:C
13 5x7m:A 443 392 0.2568 0.2144 0.2423 3.39e-16 5x7m:B, 5x7n:A, 5x7n:B
14 6knh:C 384 352 0.2378 0.2292 0.2500 9.17e-16 6knh:A, 6knh:B, 6kni:A, 6kni:B, 6kni:C, 6knk:A, 6knk:B, 6knk:C
15 1tuf:A 434 383 0.2486 0.2120 0.2402 6.77e-15 1tuf:B, 1twi:A, 1twi:B, 1twi:C, 1twi:D
16 1knw:A 421 382 0.2486 0.2185 0.2408 2.37e-14 1ko0:A
17 8d4i:A 462 394 0.2351 0.1883 0.2208 3.25e-09 8d2y:A, 8d4i:C, 8d5d:A, 8d5d:B, 8d5r:A, 8d5r:B, 8d88:A, 8d88:B
18 6n2a:A 422 373 0.2297 0.2014 0.2279 6.51e-07 6n2a:B, 6n2f:B, 6n2f:A
19 3nzp:B 591 245 0.1568 0.0981 0.2367 2.44e-06 3nzp:A
20 6hiv:CR 314 147 0.1027 0.1210 0.2585 0.010 6hiw:CR, 6hiy:CR, 6hiz:CR, 7pub:CR
21 3nzq:A 628 77 0.0595 0.0350 0.2857 0.043 3nzq:B
22 3n29:A 371 209 0.1324 0.1321 0.2344 0.045 3n29:B
23 5k2o:A 585 107 0.0811 0.0513 0.2804 0.96 3e9y:A, 3ea4:A, 8et4:A, 8et5:A, 5k3s:A, 5k6q:A, 5k6r:A, 5k6t:A, 7stq:A, 7tzz:A, 7u1d:A, 7u1u:A, 7u25:A, 6u9h:A, 6u9h:B, 6u9h:H, 6u9h:I, 6u9h:L, 6u9h:M, 6u9h:P, 6u9h:Q, 6vz8:E, 6vz8:I, 6vz8:M, 6vz8:Q, 5wj1:A, 1ybh:A, 1yhy:A, 1yhz:A, 1yi0:A, 1yi1:A, 1z8n:A
24 1y81:A 116 82 0.0622 0.1983 0.2805 1.8
25 4etp:A 379 46 0.0378 0.0369 0.3043 4.7 1f9t:A, 1f9u:A, 1f9v:A, 3kar:A
26 5fsx:A 233 81 0.0649 0.1030 0.2963 5.3 5fsx:B, 5fsy:A
27 3vyr:B 371 40 0.0405 0.0404 0.3750 7.6 3vys:B, 3vyt:B, 3vyu:B, 2z1d:A, 2z1d:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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