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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SQPGVMYIARLPHGFYEHELRGYFSQFGEITRLRVVRNKKTGASRHRAFIEFADAEVADIAARTMDKYLLFGHILTCKIV
PPAQVHPDLFKGANRRFKVVPWNKMAGRQLERPLSESQWQVKVAKEEQRRAARAEKLKEMGYEFEA

The query sequence (length=146) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8pv1:CI 152 146 1.0000 0.9605 1.0000 5.49e-108 8i9p:CI, 8i9r:CI, 8i9t:CI, 8i9v:CI, 8i9w:CI, 8i9x:CI, 8i9y:CI, 8i9z:CI, 8ia0:CI, 8pv3:CI, 8pv4:CI, 8pv7:CI, 8pvk:CI
2 8esq:o 137 115 0.4247 0.4526 0.5391 6.22e-44 8esr:o, 8etg:o, 8eth:o, 8eti:o, 8eup:o, 8euy:o, 8ev3:o
3 6c0f:o 133 143 0.3630 0.3985 0.3706 1.16e-29 7btb:o, 6cb1:o, 8e5t:o, 6elz:o, 6em1:o, 6em3:o, 6em4:o, 6em5:o, 3jct:o, 6m62:o, 7nac:o, 7ohp:o, 7ohq:o, 7ohr:o, 7ohs:o, 7ohv:o, 7ohw:o, 7r6q:o, 7r7a:o, 7u0h:o, 7uoo:o, 7uqb:o, 7uqz:o, 7v08:o, 8v83:o, 8v84:o, 8v87:o, 6ylx:o, 6yly:o, 5z3g:E
4 7ohx:o 112 89 0.2945 0.3839 0.4831 4.32e-29
5 8fkp:SH 150 96 0.3082 0.3000 0.4688 4.62e-26 8fkq:SH, 8fkr:SH, 8fks:SH, 8fkt:SH, 8fku:SH, 8fkv:SH, 8fkw:SH, 8fkx:SH, 8fky:SH, 8fkz:SH, 8fl2:SH, 8fl6:SH, 8fla:SH, 8fld:SH, 8ine:t, 8inf:t, 8ipx:t, 8ipy:t, 8ir3:t
6 6n7p:A 186 61 0.1644 0.1290 0.3934 1.08e-08 6n7r:A, 6n7x:A, 7oqc:B, 7oqe:B, 8w2o:A, 5zwn:Q
7 6g90:B 193 61 0.1644 0.1244 0.3934 1.78e-08
8 2cjk:A 167 82 0.1712 0.1497 0.3049 1.20e-07 2km8:C
9 2cjk:A 167 59 0.1027 0.0898 0.2542 0.029 2km8:C
10 2x1f:A 94 73 0.1575 0.2447 0.3151 1.73e-07 2km8:B, 2x1a:A
11 7q33:A 93 70 0.1575 0.2473 0.3286 4.01e-07 6pai:D, 6q0r:D, 6q0v:D, 6q0w:D, 6sj7:C, 6ud7:C, 6ue5:C
12 8y6o:W 167 69 0.1712 0.1497 0.3623 1.30e-06
13 7dvq:Y 140 49 0.1233 0.1286 0.3673 1.83e-06 8i0p:Y, 8i0r:Y
14 1fnx:H 174 61 0.1233 0.1034 0.2951 7.05e-06 1fxl:A, 1g2e:A
15 1fnx:H 174 47 0.1164 0.0977 0.3617 5.10e-05 1fxl:A, 1g2e:A
16 7zew:A 117 81 0.1644 0.2051 0.2963 9.86e-06 7zex:A
17 5mqf:o 223 124 0.2466 0.1614 0.2903 1.28e-05 6id1:y, 7w59:y, 7w5a:y, 7w5b:y
18 6jvx:A 87 58 0.1301 0.2184 0.3276 1.37e-05 6jvy:A
19 8i0s:Y 320 67 0.1644 0.0750 0.3582 2.48e-05 8i0t:Y, 8i0u:Y, 8i0v:Y
20 7abi:P 237 75 0.1712 0.1055 0.3333 2.53e-05 7aav:P, 7abg:P
21 8ch6:U 295 75 0.1712 0.0847 0.3333 2.62e-05 7a5p:P, 8c6j:M, 6ff4:P, 6ff7:P, 9fmd:O, 8i0p:O, 8i0r:O, 8i0s:O, 8i0t:O, 8i0u:O, 8i0v:O, 8i0w:O, 6icz:O, 6id0:O, 6id1:O, 5mqf:P, 6qdv:M, 7qtt:U, 8ro2:O, 7w59:O, 7w5a:O, 7w5b:O, 5xjc:O, 5yzg:O, 5z56:O, 5z57:O, 6zym:P
22 8ch6:V 285 67 0.1644 0.0842 0.3582 2.68e-05 7qtt:V
23 4bs2:A 174 80 0.1575 0.1322 0.2875 4.10e-05 4iuf:A, 4y00:A, 4y00:B, 4y00:C, 4y00:D, 4y0f:A, 4y0f:B
24 4bs2:A 174 53 0.1096 0.0920 0.3019 0.022 4iuf:A, 4y00:A, 4y00:B, 4y00:C, 4y00:D, 4y0f:A, 4y0f:B
25 4ed5:B 169 96 0.1644 0.1420 0.2500 4.57e-05 4ed5:A
26 4ed5:B 169 47 0.1301 0.1124 0.4043 5.19e-05 4ed5:A
27 2mb0:B 95 75 0.1507 0.2316 0.2933 5.70e-05
28 2rs2:A 84 83 0.1849 0.3214 0.3253 9.12e-05
29 5kw6:A 201 79 0.1370 0.0995 0.2532 1.41e-04 5kvy:A, 5kvy:B, 5kw1:A, 5kw1:B, 5kw6:B, 7q8a:B, 7q8a:A, 2qfj:A, 2qfj:B, 7z3x:A, 7z3x:B
30 5kw6:A 201 80 0.1301 0.0945 0.2375 0.24 5kvy:A, 5kvy:B, 5kw1:A, 5kw1:B, 5kw6:B, 7q8a:B, 7q8a:A, 2qfj:A, 2qfj:B, 7z3x:A, 7z3x:B
31 6xlv:A 203 61 0.1096 0.0788 0.2623 1.42e-04 5ev1:A, 5ev2:A, 5ev3:A, 5ev4:A, 2g4b:A, 2hzc:A, 7s3a:A, 7s3b:A, 7s3c:A, 4tu7:A, 4tu7:B, 4tu8:A, 4tu8:B, 4tu9:A, 4tu9:B, 3vaf:A, 3vaf:B, 3vag:A, 3vag:B, 3vah:B, 3vah:A, 3vai:A, 3vai:B, 3vaj:A, 3vaj:B, 3vak:A, 3vak:B, 3val:I, 3val:A, 3val:D, 3val:B, 3vam:A, 3vam:B, 5w0g:A, 6xlw:A, 6xlx:A, 2yh1:A
32 9gpj:A 184 54 0.1096 0.0870 0.2963 1.69e-04 6dcl:A, 6dcl:B, 9f4d:A, 9f4e:A, 9f4f:A, 9f4g:A, 9f4h:A, 9f4j:A, 9f4k:A, 9f4l:A, 9f4m:A, 9f4n:A, 9f4o:A, 9f4p:A, 9f4q:A, 9f4r:A, 9f4s:A, 9f4t:A, 9f4u:A, 9f4v:A, 9f4w:A, 9f4x:A, 9f4y:A, 9f4z:A, 9f50:A, 9f51:A, 9f52:A, 9f53:A, 9f54:A, 9f55:A, 9f5c:A, 9f5d:A, 9f5e:A, 9f5f:A, 9f5g:A, 9f5k:A, 9f7f:A, 9f7h:A, 5mpg:A, 5mpl:A, 1pgz:A, 1po6:A, 8rzv:A, 1u1k:A, 1u1l:A, 1u1m:A, 1u1n:A, 1u1o:A, 1u1p:A, 1u1q:A, 1u1r:A, 2up1:A, 4yoe:A
33 2n82:B 104 61 0.1301 0.1827 0.3115 2.16e-04 2err:A, 7vrl:B
34 5en1:A 184 54 0.0959 0.0761 0.2593 2.47e-04 8hni:A, 8hni:B, 8hni:G, 8hni:I, 8hni:H, 8hni:E, 8hni:K, 8hni:C, 8hni:D, 8hni:J, 8hni:F, 8hni:L, 5ho4:A, 7wm3:A, 7wm3:B, 7wm3:C, 7wm3:D, 5wwe:A, 5wwf:A, 5wwf:C, 5wwg:A
35 5en1:A 184 79 0.1712 0.1359 0.3165 0.024 8hni:A, 8hni:B, 8hni:G, 8hni:I, 8hni:H, 8hni:E, 8hni:K, 8hni:C, 8hni:D, 8hni:J, 8hni:F, 8hni:L, 5ho4:A, 7wm3:A, 7wm3:B, 7wm3:C, 7wm3:D, 5wwe:A, 5wwf:A, 5wwf:C, 5wwg:A
36 4qqb:A 169 64 0.1164 0.1006 0.2656 0.001 1b7f:A, 1b7f:B, 4qqb:B
37 4qqb:A 169 48 0.1096 0.0947 0.3333 0.008 1b7f:A, 1b7f:B, 4qqb:B
38 2rqc:A 115 63 0.1096 0.1391 0.2540 0.002
39 2mgz:B 105 58 0.1164 0.1619 0.2931 0.003 4ch1:A, 4cio:A, 2ru3:A
40 6m75:A 167 54 0.1164 0.1018 0.3148 0.003
41 6m75:A 167 60 0.0890 0.0778 0.2167 1.9
42 5m8i:A 114 63 0.1027 0.1316 0.2381 0.005
43 2leb:A 101 71 0.1507 0.2178 0.3099 0.005 2lec:A
44 6dg0:B 84 58 0.1370 0.2381 0.3448 0.006 6dg0:A
45 5ith:A 80 67 0.1233 0.2250 0.2687 0.007 5o3j:A
46 8xxm:3G 84 48 0.1096 0.1905 0.3333 0.009 5k0y:O, 8pj1:o, 8pj2:o, 8pj3:o, 8pj4:o, 8pj5:o, 8pj6:o
47 7csz:A 175 57 0.1027 0.0857 0.2632 0.010
48 7csz:A 175 69 0.1712 0.1429 0.3623 0.011
49 6gd2:A 84 71 0.1301 0.2262 0.2676 0.013 6g2k:A, 6g2k:B, 6gc5:A, 6gc5:B, 6gc5:C, 6gc5:D, 6gd2:B, 6gd3:B, 6gd3:C
50 8any:A6 74 52 0.1027 0.2027 0.2885 0.013
51 2n7c:A 89 74 0.1507 0.2472 0.2973 0.023
52 8i0v:4 161 88 0.1644 0.1491 0.2727 0.030
53 6r5k:H 394 75 0.1370 0.0508 0.2667 0.032 6r5k:D, 6r5k:F
54 1wtb:A 79 51 0.1027 0.1899 0.2941 0.043 1x0f:A
55 5x8p:v 190 72 0.1233 0.0947 0.2500 0.053 5mmj:v, 5mmm:v, 5x8r:v
56 5x8p:v 190 75 0.1164 0.0895 0.2267 0.12 5mmj:v, 5mmm:v, 5x8r:v
57 6zj3:Sg 199 69 0.1438 0.1055 0.3043 0.054
58 7q4l:A 227 75 0.1370 0.0881 0.2667 0.063
59 3smz:A 280 87 0.1301 0.0679 0.2184 0.073
60 7dco:X 128 70 0.1096 0.1250 0.2286 0.098 5gm6:V, 5zwm:X
61 2mkc:A 118 70 0.1096 0.1356 0.2286 0.13 2my3:A
62 1rk8:A 87 71 0.0959 0.1609 0.1972 0.14
63 8h6e:4R 106 65 0.1233 0.1698 0.2769 0.16 8h6j:4R, 8qp8:R, 8qp9:R, 8qpk:R, 6qw6:R, 6qx9:R, 8qxd:R, 8r08:R, 8r0a:R
64 2n3o:A 123 64 0.1438 0.1707 0.3281 0.21 2ad9:A, 8bwf:A, 8bwf:D, 8bwf:B, 8bwf:C, 8bwf:E, 8bwf:J, 8bwf:F, 8bwf:G, 8bwf:H, 8bwf:I, 8bwf:K, 8bwf:L, 8bwf:N, 8bwf:O, 8bwf:P
65 3lqv:B 115 54 0.0959 0.1217 0.2593 0.22 2f9j:B, 3lqv:A, 7q4o:F, 8qo9:B6, 8qxd:B6, 8qzs:B6, 8r08:B6, 8r09:B6, 8r0a:B6, 8r0b:B6, 8rm5:B6
66 5x3z:A 96 82 0.1370 0.2083 0.2439 0.22
67 4lmz:A 176 49 0.0822 0.0682 0.2449 0.26 3nmr:A, 3nna:A, 3nnc:A, 3nnh:A, 3nnh:C, 3nnh:B, 3nnh:D
68 4pkd:B 240 71 0.1507 0.0917 0.3099 0.39 1aud:A, 7b0y:c, 3bo2:A, 3bo3:A, 3bo4:A, 4c4w:A, 4c4w:E, 3cul:A, 3cul:B, 3cun:A, 3cun:B, 7d7v:C, 5ddo:G, 5ddo:C, 5ddp:D, 5ddp:C, 5ddq:D, 5ddq:C, 5ddr:D, 5ddr:C, 7dlz:A, 7dlz:B, 1drz:A, 7dwh:A, 7dwh:B, 1dz5:A, 1dz5:B, 3egz:A, 5fj4:A, 5fj4:E, 3g8s:A, 3g8s:B, 3g8s:C, 3g8s:D, 3g8t:A, 3g8t:B, 3g8t:C, 3g8t:D, 3g96:A, 3g96:B, 3g96:C, 3g96:D, 3g9c:A, 3g9c:B, 3g9c:C, 3g9c:D, 8gxb:C, 8gxb:D, 8gxb:F, 8gxc:C, 8gxc:D, 8gxc:F, 3hhn:B, 3hhn:D, 3iin:A, 3irw:P, 3iwn:C, 3iwn:D, 8jy0:A, 8jy0:C, 8jy0:E, 3k0j:A, 3k0j:B, 3l3c:A, 3l3c:B, 3l3c:C, 3l3c:D, 6las:E, 6las:D, 6las:C, 6lau:E, 6lau:D, 6lau:C, 6lax:D, 6lax:E, 6lax:C, 6laz:D, 6laz:E, 6laz:C, 1m5k:C, 1m5k:F, 1m5o:C, 1m5o:F, 1m5p:C, 1m5p:F, 1m5v:C, 1m5v:F, 3mum:P, 3mur:P, 3mut:P, 3muv:P, 3mxh:P, 2nz4:A, 2nz4:B, 2nz4:C, 2nz4:D, 2oih:A, 2oj3:A, 3p49:B, 4pr6:A, 4prf:A, 7qr3:A, 7qr3:B, 7qr4:A, 6qx9:1A, 3r1h:A, 3r1h:D, 3r1l:A, 3r1l:D, 1sj3:P, 1sj4:P, 1sjf:A, 6sqn:A, 6sqn:B, 6sqn:C, 6sqq:AAA, 6sqq:BBB, 6sqq:CCC, 1u6b:A, 3ucu:P, 3ucz:P, 3ud3:P, 3ud4:P, 1urn:A, 1urn:B, 1urn:C, 1vbx:A, 1vby:A, 1vbz:A, 1vc0:A, 1vc5:A, 1vc6:A, 7vpx:M, 4w90:B, 4w92:B, 1zzn:A
69 8ro0:O 342 53 0.1370 0.0585 0.3774 0.42 8ro1:O
70 7uj1:B 270 60 0.1164 0.0630 0.2833 0.47 7pu5:B, 7pu5:D, 7pu5:H, 7pu5:J, 7pu5:L, 7sp0:B, 7uj1:A
71 5ifm:C 256 75 0.1301 0.0742 0.2533 0.47 5ifm:A
72 2rra:A 99 42 0.0959 0.1414 0.3333 0.59 2kxn:B
73 8ro1:p 76 53 0.1233 0.2368 0.3396 0.63
74 6f4h:C 96 50 0.1164 0.1771 0.3400 0.67 6f4g:B, 6f4g:E, 6f4h:A, 6f4h:E
75 7zap:A 97 56 0.0822 0.1237 0.2143 0.87
76 2i2y:A 150 67 0.1370 0.1333 0.2985 1.0 9asq:H, 5bmg:A, 5bmg:B, 5bmg:H, 5bmg:D, 5bmg:E, 5bmg:F, 5bmg:G, 5bmh:A, 3v3x:C, 3v3x:D
77 2adc:A 208 69 0.1164 0.0817 0.2464 1.5
78 4f02:A 175 119 0.2055 0.1714 0.2521 1.7 1cvj:A, 1cvj:B, 1cvj:C, 1cvj:D, 1cvj:E, 1cvj:F, 1cvj:G, 1cvj:H, 4f02:D
79 7dco:R 261 55 0.1164 0.0651 0.3091 2.3 7b9v:M, 6bk8:G, 6exn:M, 5gm6:R, 5gmk:R, 6j6g:R, 6j6h:R, 6j6n:R, 6j6q:R, 5lj3:M, 5lj5:M, 5mps:M, 5mq0:M, 3tp2:A, 3tp2:B, 3u1l:A, 3u1m:A, 5wsg:R, 5y88:N, 5ylz:N
80 5lqw:F 218 55 0.1164 0.0780 0.3091 2.4
81 2xb2:D 89 72 0.0822 0.1348 0.1667 2.5 2xb2:Z
82 8wq5:A 99 50 0.0890 0.1313 0.2600 3.7 8wq5:B, 8wq5:C, 8wq5:D
83 7slp:B 321 54 0.0959 0.0436 0.2593 4.3 6d12:A, 6d12:B, 7slq:B, 4wkr:A, 4wkr:B
84 7o3e:R 72 73 0.1096 0.2222 0.2192 5.0
85 7evo:D 200 59 0.1233 0.0900 0.3051 5.1 8hk1:D, 6n3e:A, 6n3f:C, 6nsx:A
86 1q9u:B 128 20 0.0685 0.0781 0.5000 7.4
87 2a06:G 73 39 0.0822 0.1644 0.3077 9.1 1pp9:G, 1ppj:G
88 8uvz:A 160 67 0.0959 0.0875 0.2090 9.9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218