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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SQLHVAIVSSPGMGHLIPVLVLGNRLATHHNIKITILAITTTSSSAETEFLKKTTLTNEEKTIEIIPVPSVDISHLINSS
TKIFTQLRLLVREALPKIHSTIASMTHRPDALIVDIFCTQILPIAEEFNISKYTYHPTTAWTLALAIYCQVFDKEIEGEY
VELKEPLKIPGCKALRPDDVVDPLLDRSDQQYEEYVKLGKEYTDFDGILINTWEDLEPETINALRYNEKLRLLLKVPVFP
IGPLRRKVETTLNDEVIQWLDKQNNESVLFVSFGSGGTLSTKQMTELAWGLELSQQKFVWVVRPPSDTRDMSEYLPEGFL
TRTKDMGLVVPMWANQVEILSHSSVGGFLTHCGWNSTVESLTNGVPMIAWPLHAEQKMNAAMLTEELGVAIRPAVLPTKK
LVKREEIQGMVRILMQTKEGKRIKEKAKKLKKSAENALSDGGSSYNSICELVKDIRSREL

The query sequence (length=460) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8j2t:A 477 474 1.0000 0.9644 0.9705 0.0 8j2s:A, 8j2s:B, 8j2s:C, 8j2s:D, 8j2s:E, 8j2s:F, 8j2s:G, 8j2t:B, 8j2u:A, 8j2u:B, 8j2v:A, 9j9c:A, 9j9c:B, 9j9c:C, 9j9c:D, 9j9c:E, 9j9c:F, 9j9c:G, 9j9k:A, 9j9k:B
2 6jtd:A 477 469 0.4783 0.4612 0.4691 4.19e-164 6jtd:B
3 2vg8:A 465 459 0.4130 0.4086 0.4139 1.64e-118 2vce:A, 2vch:A
4 8chd:A 461 469 0.4065 0.4056 0.3987 2.74e-114 8chd:B
5 6su6:A 467 469 0.4130 0.4069 0.4051 9.97e-112 5nlm:A, 6su6:B, 6su7:A
6 5nlm:B 448 455 0.4109 0.4219 0.4154 2.66e-111
7 6jem:A 440 451 0.3935 0.4114 0.4013 1.29e-107 6jem:B, 6jem:C, 6jen:A, 6jen:B, 6jen:C
8 8ita:A 429 453 0.3457 0.3706 0.3510 4.36e-93 8inp:A
9 7q3s:A 453 466 0.3435 0.3488 0.3391 1.81e-81
10 8w53:B 479 486 0.3370 0.3236 0.3189 4.21e-73 8w53:A
11 8wp5:A 479 501 0.3413 0.3278 0.3134 2.06e-70
12 6lg1:A 429 456 0.3565 0.3823 0.3596 9.77e-69 6lg1:B
13 8hoj:A 451 476 0.3152 0.3215 0.3046 3.53e-66 8hoj:B
14 2acv:A 461 470 0.3174 0.3167 0.3106 2.07e-65 2acv:B, 2acw:A, 2acw:B
15 7bv3:A 457 473 0.3087 0.3107 0.3002 3.71e-61
16 7bv3:B 439 478 0.3043 0.3189 0.2929 1.43e-60
17 6lfz:B 439 463 0.3022 0.3166 0.3002 7.53e-59 6lfz:A
18 6lzy:A 454 483 0.3087 0.3128 0.2940 6.02e-57 6lzx:A, 6lzx:B, 6lzy:B, 7vej:A, 7vej:B, 7vek:A, 7vek:B, 7vel:A, 7vel:B
19 7va8:A 456 463 0.3130 0.3158 0.3110 9.04e-56 7va8:B, 7vaa:A, 7vaa:B
20 6llz:A 436 473 0.2978 0.3142 0.2896 1.80e-55 7cyw:A, 6llw:A, 6llw:B, 6llz:B
21 8wrk:A 434 471 0.3130 0.3318 0.3057 7.74e-51 8in7:A, 8ina:A, 8ind:A, 8inj:A, 8ino:A, 8inv:A, 8wrj:A
22 6lg0:B 444 442 0.2891 0.2995 0.3009 4.58e-50 6lg0:A, 6lg0:C, 6lg0:D, 6lg0:E, 6lg0:F
23 8cgq:A 458 469 0.3109 0.3122 0.3049 3.00e-49 6lf6:A
24 8i90:A 440 467 0.2848 0.2977 0.2805 5.00e-47 8i90:B, 8i94:A, 8i94:B
25 6l5s:A 454 470 0.3109 0.3150 0.3043 2.58e-46 6l5p:A, 6l5q:A, 6l5r:A, 6l7h:A
26 3hbj:A 445 466 0.3109 0.3213 0.3069 4.74e-46 3hbf:A
27 8inh:B 454 474 0.2848 0.2885 0.2764 8.67e-46 8inh:A
28 8hjo:B 440 231 0.1978 0.2068 0.3939 2.81e-45 8hjf:A, 8hjf:B, 8hjg:A, 8hjg:B, 8hjh:A, 8hjh:B, 8hjk:A, 8hjl:A, 8hjl:B, 8hjn:A, 8hjn:B, 8hjo:A, 8hjp:A, 8hjp:B, 8j66:A
29 8wvd:A 450 475 0.2891 0.2956 0.2800 2.19e-40 6l8z:A
30 7w0k:A 457 452 0.2804 0.2823 0.2854 3.84e-40 7w0z:A, 7w10:A, 7w1b:A, 7w1h:A
31 7w11:A 435 242 0.1957 0.2069 0.3719 4.84e-40
32 8w7y:A 474 489 0.2891 0.2806 0.2720 3.25e-39
33 2c1z:A 439 355 0.2283 0.2392 0.2958 5.50e-38 2c1x:A, 2c9z:A
34 5u6n:B 448 270 0.2043 0.2098 0.3481 9.17e-37 5u6m:A, 5u6m:B, 5u6n:A, 5u6s:A, 5u6s:B, 5v2j:A, 5v2j:B, 5v2k:A, 5v2k:B
35 6inh:A 450 203 0.1826 0.1867 0.4138 1.10e-36 6inf:A, 6ing:A, 6ini:A, 6kvi:A, 6kvj:A, 6kvk:A, 6kvl:A, 6o86:A, 6o87:A, 6o88:A
36 4rel:A 446 467 0.2826 0.2915 0.2784 1.59e-35 4rem:A, 4ren:A, 4whm:A
37 7c2x:A 490 481 0.2696 0.2531 0.2578 2.01e-35
38 5tmb:A 451 292 0.1978 0.2018 0.3116 1.72e-34 6bk0:A, 6bk1:A, 6bk2:A, 6bk3:A, 5tmd:A, 5tme:A
39 6ija:A 415 470 0.2761 0.3060 0.2702 1.84e-34 6ij9:A, 6ij9:B, 6ij9:C, 6ija:B, 6ijd:A, 6ijd:B
40 7zer:A 474 470 0.2804 0.2722 0.2745 1.82e-33 7zf0:A
41 7es1:A 408 384 0.2283 0.2574 0.2734 1.48e-32 7erx:A, 7es0:A, 7es2:A
42 8i0d:A 446 204 0.1522 0.1570 0.3431 1.10e-30 8i0e:A
43 6ij9:D 388 463 0.2652 0.3144 0.2635 6.70e-29
44 2iya:A 392 134 0.0935 0.1097 0.3209 1.90e-09 2iya:B
45 7vm0:B 406 201 0.1239 0.1404 0.2836 1.70e-08 8h5d:A, 8h5d:B, 7vm0:A
46 7xx4:A 395 83 0.0739 0.0861 0.4096 3.49e-07 2iyf:A, 2iyf:B, 4m83:A, 4m83:B, 7xx4:B
47 8sft:B 428 170 0.1000 0.1075 0.2706 3.15e-06 8gkn:A, 8gkn:B, 8sft:A, 8sft:C, 8sft:D, 8sfu:A, 8sfu:B, 8sfw:A, 8sfy:A
48 7vlb:A 385 56 0.0435 0.0519 0.3571 2.44e-04
49 7vlb:B 353 56 0.0435 0.0567 0.3571 2.62e-04
50 6kqx:A 327 97 0.0674 0.0948 0.3196 3.32e-04
51 6j31:B 387 60 0.0478 0.0568 0.3667 0.006 6j31:A, 6j31:C, 6j31:D
52 6j31:B 387 145 0.0652 0.0775 0.2069 2.4 6j31:A, 6j31:C, 6j31:D
53 7lvy:A 431 176 0.0935 0.0998 0.2443 0.061 7mco:A, 7mco:B
54 6k35:A 640 93 0.0587 0.0422 0.2903 0.16 6k35:B
55 6rie:O 822 119 0.0674 0.0377 0.2605 1.2 4ckb:A, 4ckb:D, 4ckc:A, 4ckc:D, 4cke:A, 4cke:D, 2vdw:A, 2vdw:C, 2vdw:E, 2vdw:G
56 9cf1:P 726 86 0.0565 0.0358 0.3023 1.6 9cf0:P, 9cf2:P, 9cf3:P
57 4g2t:A 356 147 0.0804 0.1039 0.2517 1.7
58 3ia7:A 397 114 0.0587 0.0680 0.2368 2.4 3ia7:B
59 3oti:A 379 30 0.0326 0.0396 0.5000 2.8 3oti:B
60 7fbg:A 268 84 0.0565 0.0970 0.3095 3.1
61 4wpc:B 288 41 0.0326 0.0521 0.3659 5.3 4wpc:A
62 3ly1:D 354 26 0.0239 0.0311 0.4231 8.0 3ly1:A, 3ly1:B, 3ly1:C
63 2iwi:B 249 54 0.0413 0.0763 0.3519 8.3 2iwi:A, 4x7q:B, 4x7q:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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