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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SPTYHSFFVYCKGPCHKVQPGKLRVQCGTCRQATLTLAQGPSCWDDVLIPNRMSGECQSPDCPGTRAEFFFKCGAHPTSD
KDTSVALNLITNNSRSIPCIACTDVRNPVLVFQCNHRHVICLDCFHLYCVTRLNDRQFVHDAQLGYSLPCVAGCPNSLIK
ELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEQGQRKVTCEGGNGLGCGFVFCRDCKEAYHEGECDS
MFEASVDQRAAEQARWEEKKTTKPCPRCNVPIEKNGGCMHMKCPQPQCKLEWCWNCGCEWNRACMGDHWFDV

The query sequence (length=312) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4zyn:B 385 318 0.9679 0.7844 0.9497 0.0 4k7d:A, 4k7d:B, 4k7d:C, 4k95:A, 4k95:B, 4k95:C, 4k95:D, 4k95:E, 4k95:F, 4k95:G, 4k95:H, 4k95:I, 4k95:J, 4k95:K, 4k95:L, 7us1:A, 8w31:A, 4zyn:A
2 6n13:B 322 322 0.8846 0.8571 0.8571 0.0 2jmo:A
3 5c1z:A 384 308 0.8558 0.6953 0.8669 0.0 4bm9:A, 5c1z:B, 5c23:A, 5c23:B, 5c9v:A, 6glc:A, 6hue:A, 6hue:B, 4i1f:A, 4i1h:A, 8ik6:C, 8ikm:A, 8ikt:A, 8ikv:C, 8ikv:A, 8jwv:A, 5n2w:A, 5n38:A, 8wzn:A, 8wzo:A
4 8ik6:A 250 309 0.6090 0.7600 0.6149 1.05e-124
5 5caw:C 315 316 0.4840 0.4794 0.4778 6.06e-107 5caw:A
6 6djw:A 317 243 0.3942 0.3880 0.5062 2.98e-78 6djx:A
7 2m48:A 141 144 0.2436 0.5390 0.5278 2.99e-42 9c5e:A, 2lwr:A
8 5tte:B 442 256 0.2051 0.1448 0.2500 7.74e-11 7b5m:H, 2m9y:A, 1wd2:A
9 7b5l:H 423 199 0.1667 0.1229 0.2613 7.75e-11 7b5n:H, 4kc9:A, 5udh:A
10 4kbl:A 395 201 0.1699 0.1342 0.2637 2.11e-10 4kbl:B, 5udh:B
11 7od1:A 430 188 0.1699 0.1233 0.2819 3.22e-10 7od1:B
12 7uy0:A 448 41 0.0449 0.0312 0.3415 1.6 7uy0:B, 7uy3:A
13 7ekp:A 396 86 0.0737 0.0581 0.2674 3.1 8cau:A, 8cau:B, 8cau:C, 8cau:D, 8cau:E, 8ci1:A, 8ci1:B, 8ci1:C, 8ci1:D, 8ci1:E, 7eki:A, 7eki:B, 7eki:C, 7eki:D, 7eki:E, 7ekp:B, 7ekp:C, 7ekp:D, 7ekp:E, 7ekt:A, 7ekt:E, 7ekt:B, 7ekt:C, 7ekt:D, 7koo:A, 7koo:B, 7koo:C, 7koo:D, 7koo:E, 7koq:A, 7koq:B, 7koq:C, 7koq:D, 7koq:E, 7kox:A, 7kox:B, 7kox:C, 7kox:D, 7kox:E, 8ut1:A, 8ut1:B, 8ut1:C, 8ut1:D, 8ut1:E, 8utb:A, 8utb:B, 8utb:C, 8utb:D, 8utb:E, 8uzj:A, 8uzj:B, 8uzj:E, 8uzj:C, 8uzj:D, 8v80:A, 8v80:B, 8v80:C, 8v80:D, 8v80:E, 8v82:A, 8v82:B, 8v82:E, 8v82:C, 8v82:D, 8v86:A, 8v86:E, 8v86:B, 8v86:C, 8v86:D, 8v88:A, 8v88:B, 8v88:C, 8v88:D, 8v88:E, 8v89:A, 8v89:B, 8v89:C, 8v89:D, 8v89:E, 8v8a:A, 8v8a:B, 8v8a:E, 8v8a:C, 8v8a:D, 8v8c:C, 8v8c:D, 8v8c:E, 8v8d:A, 8v8d:B, 8v8d:E, 8v8d:C, 8v8d:D
14 8v8c:B 374 86 0.0737 0.0615 0.2674 3.4 8v8c:A
15 8eb0:A 255 37 0.0385 0.0471 0.3243 6.2 7m4m:A, 7m4m:B, 7m4n:A, 7m4n:B, 7m4o:A
16 2dq7:X 263 32 0.0353 0.0418 0.3438 6.6
17 8s4g:S 102 67 0.0609 0.1863 0.2836 7.1 9gaw:S, 2m6n:A, 7qe7:S
18 2vtb:A 500 69 0.0609 0.0380 0.2754 9.2 2ijg:X, 2j4d:A, 2j4d:B, 2vtb:B, 2vtb:C, 2vtb:D, 2vtb:E, 2vtb:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218