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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDV
MAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTV
GKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVD
IEVLSVLASLGASVHKICTDIRLLANLKEMEEPRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLA
EAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVHEKIRVLSQQAASVVKQEGGDNDLIERIQADA
YFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPY

The query sequence (length=441) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5nx9:C 441 441 1.0000 1.0000 1.0000 0.0
2 5nx9:D 477 464 1.0000 0.9245 0.9504 0.0 2j91:A, 2j91:D, 2j91:B, 2j91:C, 5nx9:A, 5nx9:B, 5nxa:A, 5nxa:B, 5nxa:D, 5nxa:E, 5nxa:G, 5nxa:H, 5nxa:F, 2vd6:A, 2vd6:D, 2vd6:B, 2vd6:C
3 5nxa:C 418 444 0.9161 0.9665 0.9099 0.0
4 5vkw:B 469 458 0.6667 0.6269 0.6419 0.0
5 5eyt:A 472 458 0.5714 0.5339 0.5502 1.48e-172
6 2x75:A 427 376 0.2132 0.2201 0.2500 2.85e-30
7 4eei:B 423 362 0.1746 0.1820 0.2127 7.82e-13 4eei:A, 5hw2:A, 5hw2:C
8 2qga:C 455 468 0.2494 0.2418 0.2350 1.37e-09 2qga:B
9 4efc:A 452 282 0.1701 0.1659 0.2660 8.19e-07 4efc:B
10 4mx2:B 439 285 0.1678 0.1686 0.2596 7.39e-06 4mx2:A, 4mx2:C, 4mx2:D, 4mx2:E, 4mx2:F, 4mx2:G, 4mx2:H
11 7t29:A 453 229 0.1270 0.1236 0.2445 9.97e-06
12 5xnz:A 439 197 0.1338 0.1344 0.2995 8.58e-05
13 3gzh:A 469 69 0.0499 0.0469 0.3188 0.002 2ptq:A, 2ptq:B, 2ptr:A, 2ptr:B
14 7c18:B 464 179 0.1043 0.0991 0.2570 0.011 7c18:A, 7c18:C, 7c18:D
15 1fuo:A 456 163 0.0907 0.0877 0.2454 0.17 1fuo:B, 1fup:A, 1fup:B, 1fuq:A, 1fuq:B
16 8wo5:C6 315 22 0.0272 0.0381 0.5455 0.64 8wiw:Z, 8wiw:a, 8wiw:b, 8wiw:c, 8wiw:d, 8wiw:e, 8wiw:f, 8wiw:3, 8wiw:8, 8wiw:AM, 8wiw:AS, 8wiw:AY, 8wiw:Ae, 8wiw:Ak, 8wiw:Aq, 8wiw:Aw, 8wiw:A4, 8wiw:BA, 8wiw:BH, 8wiw:BO, 8wiw:BV, 8wiw:Bc, 8wiw:Bj, 8wiw:Bq, 8wiw:Bx, 8wiw:B5, 8wiw:CB, 8wiw:CI, 8wiw:CP, 8wiw:CW, 8wiw:Cd, 8wiw:Ck, 8wiw:Cr, 8wiw:Cy, 8wo5:DB, 8wo5:Em, 8wo5:DD, 8wo5:D7, 8wo5:DJ, 8wo5:DQ, 8wo5:DW, 8wo5:Dc, 8wo5:Di, 8wo5:Do, 8wo5:Du, 8wo5:D1, 8wo5:B5, 8wo5:By, 8wo5:EE, 8wo5:EK, 8wo5:EQ, 8wo5:EW, 8wo5:Ba, 8wo5:Bg, 8wo5:Bm, 8wo5:Bs, 8wo5:CA, 8wo5:CG, 8wo5:CM, 8wo5:CS, 8wo5:CY, 8wo5:Ce, 8wo5:Ck, 8wo5:Cq, 8wo5:Cw, 8wo5:Ea, 8wo5:Eg, 8woe:DG, 8woe:EC, 8woe:CB, 8woe:B5, 8woe:EJ, 8woe:EQ, 8woe:EX, 8woe:Bc, 8woe:Bj, 8woe:Bq, 8woe:Bx, 8woe:Ex, 8woe:CI, 8woe:CP, 8woe:CW, 8woe:Cd, 8woe:Ck, 8woe:Cr, 8woe:Cy, 8woe:Ey, 8woe:Ez, 8woe:E1, 8woe:E2, 8woe:E3, 8woe:E4, 8woe:C6, 8woe:DA, 8woe:DY, 8woe:De, 8woe:Dk, 8woe:Dq, 8woe:Dw, 8woe:D3, 8woe:D9, 8xp0:M, 8xp0:Y, 8xp0:S, 8xp1:Z, 8xp1:a, 8xp1:b, 8yjt:k, 8yjt:Cw, 8yjt:q, 8yjt:w, 8yjt:3, 8yjt:9, 8yjt:AE, 8yjt:AK, 8yjt:AQ, 8yjt:AW, 8yjt:Ac, 8yjt:Ai, 8yjt:Ao, 8yjt:Au, 8yjt:A1, 8yjt:A7, 8yjt:BC, 8yjt:BI, 8yjt:BO, 8yjt:BU, 8yjt:Ba, 8yjt:Bg, 8yjt:Bm, 8yjt:Bs, 8yjt:By, 8yjt:B5, 8yjt:CA, 8yjt:CG, 8yjt:CM, 8yjt:CS, 8yjt:CY, 8yjt:Ce, 8yjt:Ck, 8yjt:Cq
17 5bof:A 434 127 0.0771 0.0783 0.2677 1.1 5boe:A, 5boe:B, 5bof:B
18 8i9r:Cg 233 73 0.0476 0.0901 0.2877 3.2 8i9t:Cg
19 2oba:B 121 41 0.0340 0.1240 0.3659 3.9 2oba:A, 2oba:C, 2oba:D, 2oba:E, 2oba:F
20 7kaa:A 152 36 0.0317 0.0921 0.3889 5.7
21 5jj2:A 211 54 0.0431 0.0900 0.3519 6.7
22 1gl4:A 273 29 0.0249 0.0403 0.3793 7.8
23 4hor:A 482 105 0.0476 0.0436 0.2000 7.9 4hos:A, 4hot:A
24 7lub:B 462 59 0.0385 0.0368 0.2881 8.1 7lub:A
25 1jq3:A 295 34 0.0295 0.0441 0.3824 8.5 1jq3:C, 1jq3:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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