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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SPAELMMLTIGDVIKQLIEAHEQGKDIDLNKVKTKTAAKYGLSAQPRLVDIIAAVPPQYRKVLMPKLKAKPIRTASGIAV
VAVMCKPHRCPHISFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIV
MGGTFMALPEEYRDYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIETRPDYCMKRHLSDMLTYGCTRLEIGVQS
VYEDVARDTNRGHTVKAVCESFHLAKDSGFKVVAHMMPDLPNVGLERDIEQFTEFFENPAFRPDGLKLYPTLVIRGTGLY
ELWKSGRYKSYSPSDLVELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVRTREVGIQ
EIHHKVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFRFELGGGVSIVRELHVYGSVVPVSSRDP
TKFQHQGFGMLLMEEAERIAREEHGSGKIAVISGVGTRNYYRKIGYRLQGPYMVKMLK

The query sequence (length=538) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8ptx:C 538 538 1.0000 1.0000 1.0000 0.0 8ptz:C, 8pu0:C
2 8pty:C 440 463 0.8178 1.0000 0.9503 0.0 8avg:C
3 8asw:C 527 538 0.7305 0.7457 0.7305 0.0 8asv:C, 6qk7:C
4 5l7j:A 406 466 0.3383 0.4483 0.3906 5.53e-98 6ia6:A, 5l7l:A
5 6m7y:A 952 85 0.0372 0.0210 0.2353 0.26 6m7y:B
6 7k5b:B 4524 114 0.0520 0.0062 0.2456 0.78 8bx8:B, 7k58:B, 7kek:B
7 7vf6:A 366 209 0.1004 0.1475 0.2584 1.6 7vf6:B
8 6fd2:A 454 131 0.0520 0.0617 0.2137 2.2 6fd2:B
9 3avt:A 1203 50 0.0297 0.0133 0.3200 2.4 7abz:6, 5afi:z, 3agp:A, 3agq:A, 3avu:A, 3avv:A, 3avw:A, 3avx:A, 3avy:A, 7bbn:A, 7bbn:B, 2bvn:A, 2bvn:B, 1efm:A, 1etu:A, 4fwt:A, 2hcj:A, 2hcj:B, 2hdn:A, 2hdn:B, 2hdn:C, 2hdn:D, 2hdn:E, 2hdn:F, 2hdn:G, 2hdn:H, 2hdn:I, 2hdn:J, 2hdn:K, 2hdn:L, 5i4r:C, 5i4r:D, 5i4r:G, 5i4r:H, 3mmp:G, 5opd:A, 5opd:B, 4pc2:A, 4pc2:B, 4pc3:A, 4pc3:B, 4pc6:A, 4pc6:B, 4pc7:A, 3u6b:B, 3u6b:A, 3vnu:A, 3vnv:A, 6wd4:8, 6wd7:8, 6wd9:8, 6wda:8
10 4zfv:A 436 58 0.0353 0.0436 0.3276 2.5 5bsb:A, 5bvc:A, 5tkr:A, 4yh5:A, 4yh5:B, 4zfv:B, 4zlu:A, 4zlu:B
11 6t74:B 141 115 0.0595 0.2270 0.2783 4.6 5a8b:A, 5a8b:B, 5a8b:C, 5a8b:D, 5dkk:A, 5dkk:B, 5dkl:A, 5dkl:B, 6t73:A, 6t73:B, 6t73:C, 6t74:A
12 8bx8:A 4453 62 0.0335 0.0040 0.2903 5.2 7k58:A, 7k5b:A, 7kek:A
13 5y6q:C 748 61 0.0372 0.0267 0.3279 5.9
14 7kwd:A 473 45 0.0316 0.0359 0.3778 9.3 7kwd:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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