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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SNQEAIGLIDSGVGGLTVLKEALKQLPNERLIYLGDTARCPYGPRPAEQVVQFTWEMADFLLKKRIKMLVIACNTATAVA
LEEIKAALPIPVVGVILPGARAAVKVTKNNKIGVIGTLGTIKSASYEIAIKSKAPAIEVTSLACPKFVPIVESNQYRSSV
AKKIVAETLQALQLKGLDTLILGCTHYPLLRPVIQNVMGSHVTLIDSGAETVGEVSMLLDYFDIAHTPEAPTQPHEFYTT
GSAKMFEEIASSWLGIENLKAQQIHLG

The query sequence (length=267) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2vvt:A 269 267 0.9813 0.9740 0.9813 0.0 2jfo:A, 2jfo:B, 2jfp:A, 2jfp:B, 2vvt:B
2 3hfr:A 266 265 0.5768 0.5789 0.5811 8.48e-116 3hfr:B
3 2gzm:A 266 266 0.5918 0.5940 0.5940 2.53e-105 2gzm:B, 2gzm:C, 2gzm:D
4 2ohv:A 258 253 0.5393 0.5581 0.5692 1.49e-98
5 1zuw:C 262 263 0.5318 0.5420 0.5399 5.61e-98 1zuw:A, 1zuw:B
6 2jfq:A 265 252 0.4794 0.4830 0.5079 1.62e-81 2jfq:B
7 2dwu:B 266 256 0.4644 0.4662 0.4844 1.24e-75 2dwu:A, 2dwu:C
8 5hj7:B 260 250 0.3895 0.4000 0.4160 2.57e-62 5hj7:A
9 5ijw:B 276 254 0.4007 0.3877 0.4213 7.05e-61 5ijw:A
10 1b74:A 252 202 0.3333 0.3532 0.4406 1.66e-54
11 6dli:A 256 215 0.3521 0.3672 0.4372 1.01e-50 6dli:B, 6dli:C, 6dli:D, 5w16:A, 5w16:B, 5w16:C, 5w16:D
12 3out:B 264 259 0.3408 0.3447 0.3514 1.12e-44 3out:A, 3out:C
13 3uhf:A 255 258 0.3408 0.3569 0.3527 9.70e-43 3uhf:B, 3uho:A, 3uho:B
14 7uj5:A 256 260 0.3521 0.3672 0.3615 3.56e-42 4b1f:A, 4b1f:B, 8eb3:A, 8eb3:B, 2jfx:A, 2jfx:B, 2jfy:A, 2jfy:B, 2jfz:A, 2jfz:B, 8tba:A, 8tba:B, 7uj5:B, 7uj5:C, 7uj5:D, 5w1q:A, 5w1q:B, 2w4i:A, 2w4i:B, 2w4i:E, 2w4i:F
15 2jfn:A 266 217 0.2509 0.2519 0.3088 5.30e-24
16 3ivd:A 499 155 0.1536 0.0822 0.2645 0.018 3ivd:B, 3ive:A
17 6lpn:B 467 111 0.1161 0.0664 0.2793 0.052 6lpn:A, 6lpp:A, 6lpp:B, 6lpq:A, 6lpq:B, 6lpt:A, 6lpt:B, 6lpu:A, 6lpu:B, 6lpx:A, 6lpx:B
18 5v8f:3 654 73 0.0861 0.0352 0.3151 4.7 5bk4:B, 5bk4:3, 6eyc:3, 6f0l:3, 6f0l:B, 3ja8:3, 7p30:3, 7p30:B, 7p5z:3, 7p5z:B, 6ptn:j, 6ptn:3, 6pto:i, 6pto:3, 6rqc:3, 6sko:3, 6u0m:3, 5u8s:3, 5u8t:3
19 1gyc:A 499 156 0.1498 0.0802 0.2564 7.6
20 3e0x:A 245 29 0.0562 0.0612 0.5172 7.8 3e0x:B
21 8w7m:3 619 59 0.0749 0.0323 0.3390 7.9 8b9a:3, 8b9b:3, 8b9c:3, 7pmk:3, 6skl:3, 8xgc:3
22 5kod:D 566 64 0.0712 0.0336 0.2969 9.2

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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