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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SNFINIHVLISHSPSCLNRDDMNMQKDAIFGGKRRVRISSQSLKRAMRKSGYYAQNIGESSLRTIHLAQLRDVLRQKLGE
RFDQKIIDKTLALLSGKSVDEAEKISADAVTPWVVGEIAWFCEQVAKAEADNLDDKKLLKVLKEDIAAIRVNLQQGVDIA
LSGRMATSGMMTELGKVDGAMSIAHAITTHQVDSDIDWFTAVDDLQELGTQEFSSGVFYRYANINLAQLQENLGGASREQ
ALEIATHVVHMLATEVPGAKQRTYAAFNPADMVMVNFSDMPLSMANAFEKAVKAKDGFLQPSIQAFNQYWDRVANGYGLN
GAAAQFSLSDVDPITAQVKQMPTLEQLKSWVRNNGE

The query sequence (length=356) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5cd4:F 363 361 1.0000 0.9807 0.9861 0.0 5cd4:B, 5cd4:C, 5cd4:D, 5cd4:E, 5cd4:G, 5cd4:N, 5cd4:O, 5cd4:P, 5cd4:Q, 5cd4:R, 5cd4:S, 5h9e:E, 5h9e:F, 5h9e:G, 5h9e:H, 5h9e:I, 5h9f:E, 5h9f:F, 5h9f:G, 5h9f:H, 5h9f:I, 4qyz:D, 4qyz:E, 4qyz:F, 4qyz:G, 4qyz:H, 4tvx:F, 4tvx:D, 4tvx:E, 4tvx:C, 4tvx:B, 4tvx:G, 4tvx:R, 4tvx:P, 4tvx:Q, 4tvx:O, 4tvx:N, 4tvx:S, 4u7u:E, 4u7u:F, 4u7u:G, 4u7u:H, 4u7u:I, 4u7u:J, 4u7u:Q, 4u7u:R, 4u7u:S, 4u7u:T, 4u7u:U, 4u7u:V
2 5h9e:D 318 355 0.8933 1.0000 0.8958 0.0 5h9f:D
3 4qyz:I 256 208 0.5337 0.7422 0.9135 5.24e-135
4 4qyz:I 256 62 0.1657 0.2305 0.9516 3.02e-35
5 6c66:B 334 321 0.2865 0.3054 0.3178 3.12e-38
6 6c66:C 367 335 0.3034 0.2943 0.3224 2.34e-37 6c66:D, 6c66:E, 6c66:F, 5u07:E, 5u07:F, 5u07:G, 5u07:H, 5u0a:E, 5u0a:F, 5u0a:G, 5u0a:H
7 8yb6:G 377 332 0.2837 0.2679 0.3042 1.92e-34 8yb6:D, 8yb6:E, 8yb6:F, 8yb6:H, 8yha:E, 8yha:F, 8yha:G, 8yha:H
8 8yha:D 355 328 0.2753 0.2761 0.2988 5.46e-31
9 6c66:H 329 329 0.2753 0.2979 0.2979 1.30e-24 5u07:I, 5u0a:I
10 5u07:D 260 166 0.1742 0.2385 0.3735 1.81e-24 5u0a:D
11 5u07:D 260 46 0.0618 0.0846 0.4783 1.04e-07 5u0a:D
12 8yb6:I 268 169 0.1601 0.2127 0.3373 4.66e-21 8yha:I
13 8yb6:I 268 48 0.0702 0.0933 0.5208 6.36e-09 8yha:I
14 4oc6:B 243 129 0.1039 0.1523 0.2868 0.60 1lyb:B, 1lyb:D, 4obz:B, 4od9:B, 4od9:D, 6qbg:B, 6qbh:B, 6qcb:B
15 4fgm:A 587 43 0.0393 0.0239 0.3256 1.6
16 7zr1:A 529 68 0.0646 0.0435 0.3382 3.8 4yke:A, 4yke:B, 7zr1:B
17 4jq6:B 203 37 0.0393 0.0690 0.3784 8.8 4jq6:A, 4jq6:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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