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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SNFGVDFVIHYKVPAAERDEAEAGFVQLIRALTTVGLATEVRHGENESLLVFVKVSPDLFAKQVYRARLGDWLHGVRVEA
ERLRLIYLMITKPHNEGGAGVTPTNAKWKHVESIFPLHSHSFNKEWIKKWSSKYTLEQTDIDNIRDKFGESVAFYFAFLR
SYFRFLVIPSAFGFGAWLLLGQFSYLYALLCGLWSVVFFEYWKKQEVDLAVQWGVRGVSSIQQSRPEFEWEHEAKVYPPM
KRVKTQLLQIPFALACVVALGALIVTCNSLEVFINEVYSGPQYLGFLPTIFLVIGTPTISGVLMGAAEKLNAMENYATVD
AHDAALIQKQFVLNFMTSYMALFFTAFVYIPFGHILHPFLNFWRINPARISNQMFYFTVTPQIVNFATEVVVPYIKQQAF
EEAEFLQRVREECTLEEYDVSGDYREMVMQFGYVAMFSVAWPLAACCFLVNNWVELRSDALKIAISSRRPIPWRTDSIGP
WLTALSFLSWLGSITSSAIVYLCSNAWGLLLSILFAEHFYLVVQLAVRFVLSKLPGLQKERKERFQTKKRLLTPEEMFWQ
RQRGMQETIEIGRRMIEQQ

The query sequence (length=579) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8tpt:B 571 579 0.9862 1.0000 0.9862 0.0
2 8tpm:B 615 613 0.9845 0.9268 0.9299 0.0 8tpm:A, 8tpo:B, 8tpo:A, 8tpp:A, 8tpp:B, 8tpr:A, 8tpr:B
3 6qm5:A 673 668 0.9983 0.8588 0.8653 0.0 6qm5:B, 6qm9:A, 6qm9:B, 6qma:A, 6qma:B, 6qmb:A, 6qmb:B, 8toi:A, 8toi:B, 8tok:A, 8tok:B, 8tol:A, 8tol:B, 4wis:A, 4wis:B, 4wit:A, 4wit:B
4 6oy3:B 594 609 0.9516 0.9276 0.9048 0.0 6oy3:A, 8tpn:A, 8tpn:B, 8tpq:A, 8tpq:B, 8tps:A, 8tps:B, 8tpt:A
5 7rx2:B 615 615 0.5354 0.5041 0.5041 0.0 6e0h:B, 6e0h:A, 6e1o:B, 6e1o:A, 7rwj:B, 7rwj:A, 7rx2:A
6 7rx3:B 591 595 0.5285 0.5178 0.5143 0.0 7rx3:A, 7rxa:A, 7rxa:B
7 7rxg:B 650 648 0.5371 0.4785 0.4799 0.0 7rxg:A, 7rxh:A
8 7rxb:A 548 577 0.5112 0.5401 0.5130 0.0 7rxb:B
9 6r7x:A 629 469 0.2211 0.2035 0.2729 1.63e-38 5oc9:A, 5oc9:B, 6r65:A, 6r65:B, 6r7x:B, 6r7y:A, 6r7y:B
10 8sun:B 743 621 0.2245 0.1750 0.2093 6.77e-21 8b8k:A, 8b8k:B, 8b8m:A, 6qp6:A, 6qp6:B, 8sur:B, 8tag:B, 8tai:B, 8tal:B
11 8qzc:A 701 466 0.1848 0.1526 0.2296 7.73e-21 8qzc:B
12 7zk3:A 721 476 0.1848 0.1484 0.2248 6.16e-19 7b5c:A, 7b5c:B, 7b5e:A, 7b5e:B, 5oyb:A, 5oyb:B, 7zk3:B
13 8bc1:A 527 439 0.1693 0.1860 0.2232 7.66e-19 8bc1:B
14 8bc0:B 636 572 0.2107 0.1918 0.2133 1.03e-18 6p48:A, 6p48:B, 6p49:A, 6p49:B, 6qpc:A, 6qpc:B
15 8b8j:A 709 588 0.2245 0.1834 0.2211 6.43e-17 8b8j:B, 8b8q:A, 8b8q:B, 8bc0:A, 6p46:A, 6p46:B, 8sun:A, 8sur:A, 8tag:A, 8tai:A, 8tal:A
16 8b8m:B 682 584 0.2073 0.1760 0.2055 1.64e-15
17 6bgi:A 510 433 0.1727 0.1961 0.2309 5.56e-14 6bgi:B
18 6bgj:A 490 420 0.1675 0.1980 0.2310 1.87e-13 6bgj:B
19 2z02:A 242 68 0.0345 0.0826 0.2941 1.3 2yzl:A, 2z02:B
20 1t8h:A 272 47 0.0276 0.0588 0.3404 3.8 6t0y:A, 6t1b:A
21 1j2x:A 70 35 0.0242 0.2000 0.4000 5.0 2k7l:A, 1onv:A
22 4nf9:A 216 53 0.0311 0.0833 0.3396 5.9 4nf9:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218