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●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
>protein
SMVRVAINGFGRIGRNFMRCWLQRKANSKLEIVGINDTSDPRTNAHLLKYDSMLGIFQDAEITADDDCIYAGGHAVKCVS
DRNPENLPWSAWGIDLVIEATGVFTSREGASKHLSAGAKKVLITAPGKGNIPTYVVGVNHHTYDPSEDIVSNASCTTNCL
APIVKVLHEAFGIQQGMMTTTHSYTGDQRLLDASHRDLRRARAAAMNIVPTSTGAAKAVGLVIPELQGKLNGIALRVPTP
NVSVVDFVAQVEKPTIAEQVNQVIKEASETTMKGIIHYSELELVSSDYRGHNASSILDASLTMVLGGNLVKVVAWYDNEW
GYSQRVLDLAEHMAAHWA

The query sequence (length=338) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length 		Aligned
length 		Identity
(normalized by query) 		Identity
(normalized by hit) 		Identity (normalized
by aligned length) 		E-value Homologs
to hit
1 6ghr:B 342 338 1.0000 0.9883 1.0000 0.0 4boy:A, 4boy:B, 6gfo:A, 6gfo:B, 6gfo:C, 6gfo:D, 6gfp:A, 6gfp:B, 6gfq:B, 6gfq:A, 6gfr:A, 6gfr:B, 6gg7:B, 6gg7:A, 6ghl:A, 6ghl:D, 6ghl:B, 6ghl:C, 6ghr:D, 6ghr:A, 6ghr:C, 6gve:D, 6gve:A, 6gve:E, 6gve:F, 6gve:I, 6gve:K, 6gve:N, 6gve:O, 3zcx:A, 3zcx:B, 3zdf:B, 3zdf:A
2 3b1j:A 338 339 0.7160 0.7160 0.7139 5.06e-163 3b1j:B, 3b1k:A, 3b1k:H, 3b1k:B, 3b1k:G, 3b20:A, 3b20:B, 3b20:O, 3b20:P, 3b20:Q, 3b20:R, 2d2i:A, 2d2i:B, 2d2i:O, 2d2i:P, 2d2i:Q, 2d2i:R, 2duu:A, 2duu:B, 2duu:O, 2duu:P, 2duu:Q, 2duu:R
3 1nbo:O 337 335 0.6627 0.6647 0.6687 1.58e-156 1jn0:O, 1jn0:A, 1jn0:B, 1nbo:A, 1nbo:B, 2pkq:P, 2pkq:R, 2pkq:S, 2pkr:O, 2pkr:R, 2pkr:P, 2pkr:Q, 2pkr:A, 2pkr:B, 2pkr:C, 2pkr:D, 2pkr:H, 2pkr:I, 2pkr:L, 2pkr:M, 7q53:P, 7q53:R, 7q54:R, 7q54:P, 7q54:B, 7q54:D, 7q55:P, 7q55:R, 7q55:B, 7q55:D, 7q55:F, 7q55:H, 7q55:J, 7q55:L, 7q56:J, 7q56:L, 7q56:B, 7q56:D, 7q56:R, 7q56:P, 7q56:H, 7q56:F, 7q57:P, 7q57:R, 7q57:B, 7q57:D, 7q57:H, 7q57:F, 7q57:J, 7q57:L, 7q57:N, 7q57:T, 1rm3:O, 1rm3:A, 1rm3:B, 1rm4:O, 1rm4:A, 1rm4:B, 1rm5:O, 1rm5:A, 1rm5:B
4 3k2b:A 337 336 0.6509 0.6528 0.6548 3.13e-143 3k2b:B, 3k2b:C, 3k2b:D, 3k2b:E, 3k2b:F, 3k2b:G, 3k2b:H, 3k2b:O, 3k2b:Q, 6kez:A, 6kez:B, 6kez:C, 6kez:D, 6kez:E, 6kez:F, 6kez:G, 6kez:H, 3qv1:A, 3qv1:D, 3qv1:B, 3qv1:C, 3qv1:F, 3qv1:E, 3rvd:A, 3rvd:D, 3rvd:B, 3rvd:C, 3rvd:O, 3rvd:Q, 3rvd:F, 3rvd:G, 3rvd:E, 3rvd:H
5 3cmc:O 334 334 0.5799 0.5868 0.5868 4.77e-140 3cmc:P, 3cmc:Q, 3cmc:R, 1dbv:O, 1dbv:P, 1dbv:Q, 1dbv:R, 2dbv:O, 2dbv:P, 2dbv:Q, 2dbv:R, 3dbv:O, 3dbv:P, 3dbv:Q, 3dbv:R, 4dbv:O, 4dbv:P, 4dbv:Q, 4dbv:R, 1gd1:O, 1gd1:P, 1gd1:Q, 1gd1:R, 1npt:O, 1npt:P, 1npt:Q, 1npt:R, 1nq5:O, 1nq5:Q, 1nq5:A, 1nq5:C, 1nqa:O, 1nqa:P, 1nqa:Q, 1nqa:R, 1nqo:O, 1nqo:Q, 1nqo:A, 1nqo:C
6 7q54:C 368 338 0.6243 0.5734 0.6243 7.91e-140 2pkq:O, 2pkq:Q, 2pkq:T, 7q53:O, 7q53:Q, 7q54:Q, 7q54:O, 7q54:A, 7q55:O, 7q55:Q, 7q55:A, 7q55:C, 7q55:E, 7q55:G, 7q55:I, 7q55:K, 7q56:K, 7q56:E, 7q56:I, 7q56:A, 7q56:G, 7q56:C, 7q56:Q, 7q56:O, 7q57:O, 7q57:Q, 7q57:A, 7q57:C, 7q57:G, 7q57:E, 7q57:I, 7q57:K, 7q57:M, 7q57:S
7 7zq3:R 348 336 0.6361 0.6178 0.6399 6.06e-137 7zq3:O, 7zq4:O, 7zq4:R, 7zqk:O, 7zqk:R
8 1hdg:O 332 330 0.5473 0.5572 0.5606 9.89e-130 1hdg:Q
9 3hja:A 334 338 0.5385 0.5449 0.5385 1.41e-129 3hja:B, 3hja:C, 3hja:D
10 2ep7:B 339 341 0.5473 0.5457 0.5425 2.22e-124 2ep7:A
11 3gnq:C 335 333 0.5207 0.5254 0.5285 9.75e-122 3gnq:B, 3gnq:D, 3gnq:E, 3gnq:F, 3gnq:G, 3gnq:H
12 7xzg:A 334 334 0.5059 0.5120 0.5120 5.69e-119 7xzg:B, 7xzg:C, 7xzg:D
13 3l0d:A 332 332 0.4970 0.5060 0.5060 1.39e-118 3l0d:B
14 1obf:O 335 327 0.5030 0.5075 0.5199 1.79e-118 1obf:P
15 3doc:A 335 328 0.4941 0.4985 0.5091 7.07e-118 3doc:B, 3doc:C, 3doc:D
16 8hrq:B 336 334 0.5296 0.5327 0.5359 3.25e-116 8hro:A, 8hro:B, 8hrp:A, 8hrp:B, 8hrp:C, 8hrp:D, 8hrp:E, 8hrp:F, 8hrp:G, 8hrp:H, 8hrq:A, 8hrr:A, 8hrr:B, 8hrs:A, 8hrs:B, 8hrs:C, 8hrs:D, 8hrt:A, 8hrt:B, 8hrt:C, 8hrt:D
17 1cer:O 331 330 0.5266 0.5378 0.5394 3.50e-116 1cer:P, 1cer:Q, 1cer:R, 1cer:A, 1cer:B, 1cer:C, 1cer:D, 2g82:O, 2g82:P, 2g82:Q, 2g82:R, 2g82:A, 2g82:B, 2g82:C, 2g82:D, 1vc2:A
18 8br4:A 339 330 0.5148 0.5133 0.5273 5.04e-116 8br4:B, 8br4:C, 8br4:D, 8br4:E, 8br4:F, 8br4:G, 8br4:H, 8br4:I, 8br4:J, 8br4:K, 8br4:L, 8br4:M, 8br4:N, 8br4:O, 8br4:P
19 6nlx:C 335 331 0.5030 0.5075 0.5136 2.03e-115 6nlx:B, 6nlx:D, 5ur0:A, 5ur0:B, 5ur0:C, 5ur0:D
20 4mvj:B 332 333 0.4911 0.5000 0.4985 6.29e-115 1dc4:A, 1dc4:B, 1dc6:A, 1dc6:B, 1gad:O, 1gad:P, 1gae:O, 1gae:P, 6io6:A, 4mvj:A, 4mvj:C, 4mvj:D, 4mvj:E, 4mvj:F, 4mvj:G, 4mvj:I, 4mvj:J, 4mvj:K, 4mvj:L, 4mvj:M, 4mvj:O, 4mvj:P, 6utm:A, 6utm:B, 6utn:A, 6utn:B, 6uto:A, 6uto:B, 2vyn:A, 2vyn:B, 2vyn:C, 2vyv:A, 2vyv:B, 2vyv:C, 5za0:A
21 8oha:B 336 337 0.5178 0.5208 0.5193 6.81e-115 8oha:A, 8oha:C, 8oha:D, 8oha:E, 8oha:F, 8oha:G, 8oha:H
22 4p8r:A 331 333 0.5030 0.5136 0.5105 2.00e-114 4p8r:B, 4p8r:C, 4p8r:D
23 3pym:A 332 337 0.5089 0.5181 0.5104 2.04e-114 3pym:B
24 6ok4:A 334 332 0.4763 0.4820 0.4849 2.66e-114 6ok4:B, 6ok4:C, 6ok4:D, 6wyc:A, 6wyc:B, 6wyc:C, 6wyc:D, 6x2e:A, 6x2e:C, 6x2e:D
25 8de5:A 338 335 0.4970 0.4970 0.5015 9.43e-114
26 6qun:O 334 337 0.4970 0.5030 0.4985 2.24e-112 6qun:R, 6quq:O, 6quq:R, 4z0h:O, 4z0h:R
27 3e5r:O 336 337 0.4941 0.4970 0.4955 3.41e-110 3e5r:A, 3e5r:B, 3e5r:C, 3v1y:O, 3v1y:A, 3v1y:B, 3v1y:C
28 1ywg:O 337 337 0.4911 0.4926 0.4926 4.06e-110 2b4r:O, 2b4r:P, 2b4r:Q, 2b4r:R, 2b4t:O, 2b4t:P, 2b4t:Q, 2b4t:R, 1ywg:P, 1ywg:Q, 1ywg:R
29 3dmt:A 359 353 0.5089 0.4791 0.4873 4.21e-110 3dmt:B, 3dmt:C, 3dmt:D, 3ids:D, 1k3t:C, 1ml3:B, 1ml3:C, 1ml3:D, 1qxs:C, 1qxs:D, 1qxs:A, 1qxs:B, 2x0n:A, 2x0n:B, 2x0n:O, 2x0n:P, 2x0n:Q, 2x0n:R
30 4lsm:A 331 335 0.4763 0.4864 0.4806 6.98e-110 4lsm:B
31 3cif:A 338 338 0.4911 0.4911 0.4911 5.37e-109 3cif:B, 3cif:C, 3cif:D, 3cps:A, 3cps:B, 8pvf:A, 1vsv:A, 1vsv:B, 1vsv:C, 1vsv:D
32 3gpd:R 334 335 0.4822 0.4880 0.4866 1.65e-108 3gpd:G
33 1dss:G 333 332 0.4763 0.4835 0.4849 2.26e-108 1dss:R, 1gpd:G, 1gpd:R, 1ihx:A, 1ihx:B, 1ihx:C, 1ihx:D, 1ihy:A, 1ihy:B, 1ihy:C, 1ihy:D, 1szj:G, 1szj:R
34 5m6d:A 346 339 0.4941 0.4827 0.4926 5.77e-106 6fzh:A, 6fzh:B, 6ite:P, 6ite:Q, 6ite:R, 6ite:O
35 5vmt:B 334 338 0.4882 0.4940 0.4882 9.01e-106 5vmt:A, 5vmt:C, 5vmt:D, 5vmt:F, 5vmt:G, 5vmt:H
36 6m61:O 336 335 0.4675 0.4702 0.4716 2.98e-105 6ade:A, 5ddi:P, 5ddi:R, 5ddi:S, 6iq6:A, 6iq6:B, 6iq6:C, 6iq6:D, 6iq6:E, 1j0x:P, 1j0x:R, 6lgj:A, 6lgj:B, 6lgj:C, 6lgj:D, 6lgk:A, 6lgk:B, 6lgk:C, 6lgm:A, 6lgm:B, 6lgm:C, 6m61:Q, 6m61:P, 4o59:O, 4o59:P, 4o59:R, 4o59:Q, 4o63:P, 4o63:Q, 4o63:R, 8p5f:AAA, 8p5f:DDD, 8p5f:EEE, 8p5f:GGG, 5tso:P, 5tso:R, 5tso:S, 7u5m:A, 7u5m:B, 7u5m:C, 7u5m:D, 1u8f:P, 1u8f:Q, 1u8f:R, 4wnc:O, 4wnc:E, 4wnc:A, 4wnc:B, 4wnc:C, 4wnc:D, 4wni:O, 4wni:A, 4wni:B, 1znq:O, 1znq:P, 1znq:R, 1znq:Q
37 7jwk:C 333 336 0.5030 0.5105 0.5060 2.93e-104 7jwk:A, 7jwk:B, 7jwk:D
38 7bew:A 330 332 0.4408 0.4515 0.4488 4.25e-104 7bex:A
39 5utm:A 345 340 0.4882 0.4783 0.4853 1.60e-103 5jy6:A, 5jy6:B, 5jy6:C, 5jy6:D, 5jya:A, 5jya:B, 5jya:C, 5jya:D, 5jye:A, 5jye:C, 4qx6:A, 4qx6:B, 4qx6:C, 4qx6:D, 5utl:A, 5utl:B, 5utl:C, 5utl:D, 5utm:B, 5utm:C, 5utm:D, 5v8x:A, 5v8x:B, 5v8x:C, 5v8x:D, 5y37:A, 5y37:B
40 1a7k:A 358 350 0.4882 0.4609 0.4714 2.74e-103 1a7k:B, 1a7k:C, 1a7k:D, 1gyp:A, 1gyp:B, 1gyp:C, 1gyp:D, 1gyq:A, 1gyq:B, 1gyq:C, 1gyq:D, 1i32:A, 1i32:B, 1i32:C, 1i32:D, 1i32:E, 1i32:F, 1i33:A, 1i33:B, 1i33:C, 1i33:D, 1i33:E, 1i33:F
41 2vyn:D 334 335 0.4615 0.4671 0.4657 5.30e-103 2vyv:D
42 6fzi:B 332 331 0.4911 0.5000 0.5015 1.27e-102 6fzi:A, 6fzi:C, 6fzi:D
43 6m5x:O 334 328 0.4645 0.4701 0.4787 1.56e-102 6m5x:R, 6m5x:P, 6m5x:Q
44 3h9e:P 337 332 0.4527 0.4540 0.4608 2.47e-101 5c7o:O, 5c7o:P, 3h9e:O, 3pfw:O, 3pfw:P
45 4k9d:A 338 344 0.4615 0.4615 0.4535 3.65e-101 4k9d:B, 4k9d:C, 4k9d:D, 4k9d:E, 4k9d:F, 4k9d:G, 4k9d:H
46 2i5p:O 309 337 0.4615 0.5049 0.4629 2.27e-100 2i5p:P
47 6px2:A 332 335 0.4734 0.4819 0.4776 3.49e-99 6px2:B, 6px2:C, 6px2:D, 6px2:E, 6px2:F, 6px2:G, 6px2:H
48 3lvf:P 338 338 0.4763 0.4763 0.4763 7.79e-98 3hq4:R, 3hq4:O, 3hq4:P, 3hq4:Q, 3k73:Q, 3k73:O, 3k73:P, 3k73:R, 3k9q:Q, 3k9q:O, 3k9q:P, 3k9q:R, 3ksd:Q, 3ksd:R, 3ksd:O, 3ksd:P, 3ksz:O, 3ksz:P, 3ksz:R, 3ksz:Q, 3kv3:O, 3kv3:Q, 3kv3:R, 3kv3:P, 3l4s:Q, 3l4s:P, 3l4s:O, 3l4s:R, 3l6o:Q, 3l6o:P, 3l6o:R, 3l6o:O, 3lc1:P, 3lc1:R, 3lc1:O, 3lc1:Q, 3lc2:O, 3lc2:Q, 3lc2:R, 3lc2:P, 3lvf:R, 3lvf:O, 3lvf:Q, 5t73:A, 5t73:B, 5t73:C, 5t73:D, 3vaz:P, 3vaz:R, 3vaz:O, 3vaz:Q, 3vaz:B, 3vaz:A
49 9iil:A 341 338 0.4260 0.4223 0.4260 3.65e-96 9iil:B, 9iil:C, 9iil:D, 9iim:A, 9iim:C, 9iim:B, 9iim:D, 9ij6:A, 9ij6:C, 9ij6:B, 9ij6:D, 8zn1:A, 8zn1:C, 8zn1:B, 8zn1:D, 8zn4:A, 8zn4:B, 8zn4:C, 8zn4:D, 8zoz:A, 8zoz:C, 8zoz:B, 8zoz:D
50 7c5o:O 338 338 0.4675 0.4675 0.4675 1.82e-95 7c5f:O, 7c5f:P, 7c5f:Q, 7c5f:R, 7c5g:O, 7c5g:P, 7c5g:Q, 7c5g:R, 7c5h:O, 7c5h:P, 7c5h:Q, 7c5h:R, 7c5i:O, 7c5i:P, 7c5i:Q, 7c5i:R, 7c5j:O, 7c5j:P, 7c5j:Q, 7c5j:R, 7c5k:O, 7c5k:P, 7c5k:Q, 7c5k:R, 7c5l:O, 7c5l:P, 7c5l:Q, 7c5l:R, 7c5m:O, 7c5m:P, 7c5m:Q, 7c5m:R, 7c5n:O, 7c5n:P, 7c5n:Q, 7c5n:R, 7c5o:P, 7c5o:Q, 7c5o:R, 7c5p:O, 7c5p:P, 7c5p:Q, 7c5p:R, 7c5q:O, 7c5q:P, 7c5q:Q, 7c5q:R, 7c5r:O, 7c5r:P, 7c5r:Q, 7c5r:R, 7c7k:O, 7c7k:P, 7c7k:Q, 7c7k:R
51 5ld5:C 342 334 0.4734 0.4678 0.4790 4.06e-95 5ld5:A, 5ld5:B, 5ld5:D
52 7www:A 336 332 0.4615 0.4643 0.4699 2.76e-94
53 3sth:C 340 345 0.4586 0.4559 0.4493 1.74e-93 3sth:A, 3sth:B, 3sth:D
54 2xf8:M 327 333 0.4112 0.4251 0.4174 9.19e-92 2xf8:A, 2xf8:C, 2xf8:E, 2xf8:G, 2xf8:I, 2xf8:K, 2xf8:O
55 8hmn:D 340 332 0.4438 0.4412 0.4518 4.84e-85 8hmn:A, 8hmn:B, 8hmn:C, 6iqm:A, 6iqm:B, 6iqm:C, 6iqm:D
56 5vmt:E 293 333 0.4260 0.4915 0.4324 3.69e-81
57 8jb1:A 468 343 0.4024 0.2906 0.3965 4.76e-72 8jb1:B
58 3kv6:D 448 108 0.0651 0.0491 0.2037 0.065 3kv5:D, 3kv5:A, 3kv6:A, 3kv9:A, 3kva:A, 3u78:A
59 1cf2:P 336 177 0.1213 0.1220 0.2316 0.14 1cf2:R, 1cf2:O, 1cf2:Q
60 3tz6:A 342 98 0.0651 0.0643 0.2245 0.50 3vos:A
61 3pyl:C 361 96 0.0680 0.0637 0.2396 0.76 2gz1:A, 2gz1:B, 2gz2:A, 2gz2:B, 2gz3:A, 2gz3:B, 2gz3:C, 2gz3:D, 3pwk:A, 3pwk:B, 3pws:A, 3pws:B, 3pyl:A, 3pyl:B, 3pyx:A, 3pyx:B, 3pzb:A, 3pzb:B, 3q11:A, 3q11:B, 3q1l:A, 3q1l:B, 3q1l:C, 3q1l:D, 4r3n:A, 4r3n:B, 4r3w:A, 4r3w:B, 4r41:A, 4r41:B, 4r4j:A, 4r4j:B, 4r51:A, 4r51:B, 4r54:A, 4r54:B, 4r5h:A, 4r5h:B
62 2r00:C 336 150 0.1095 0.1101 0.2467 1.1
63 3wyc:A 327 93 0.0828 0.0856 0.3011 1.2 5gz3:A, 5gz3:B, 5gz6:A, 3wyc:B
64 4o30:A 217 32 0.0385 0.0599 0.4062 2.0 4o30:B, 5va6:A, 5va6:B, 5vac:A, 5vah:A, 5vah:B, 5vbc:A, 5vbc:B
65 5j5d:A 297 83 0.0769 0.0875 0.3133 3.5 3l21:B, 1xxx:A, 1xxx:B, 1xxx:C, 1xxx:D, 1xxx:E, 1xxx:F, 1xxx:G, 1xxx:H
66 5ynv:B 313 49 0.0473 0.0511 0.3265 3.7 5y72:A, 5y72:B, 5y7c:A, 5y7c:B, 5y84:A, 5y84:B, 5ynt:A, 5ynt:B, 5ynu:A, 5ynu:B, 5ynv:A, 5ynw:A, 5ynw:B
67 1ys4:A 348 38 0.0296 0.0287 0.2632 4.6 1ys4:B
68 7arc:G 682 79 0.0769 0.0381 0.3291 4.6 7ard:G
69 1c5c:H 215 77 0.0473 0.0744 0.2078 7.9
70 8jya:B 191 49 0.0414 0.0733 0.2857 8.5 8hjt:C, 8hjt:D, 8jy9:A, 8jy9:B, 8jyf:B
71 2dc1:A 236 109 0.0888 0.1271 0.2752 9.1 2dc1:B
72 6ofs:A 905 48 0.0473 0.0177 0.3333 9.9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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