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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SMSNRLIFDADWLVPEQVQVAGQAIQYYAARNIQYVQHPVAAIQVLNVFVPAAYLHGSSVNGYQRATAPILMPNTVGGYL
PGPADDPQRVTWPTNAGTIQQALKRGYVVVAAGIRGRTTVDKSGQRVGQAPAFIVDMKAAIRYVKYNQGRLPGDANRIIT
NGTAAGGATSALAGASGNSAYFEPALTALGAAPATDDIFAVSAYCPIHNLEHADMAYEWQFNGINDWHRYQPVAGTTKNG
RPKFEPVSGQLTVEEQALSLALKAQFSTYLNQLKLTASDGTHLTLNEAGMGSFRDVVRQLLISSAQTAFDQGTDIHKYAG
FVVTGNQVTDLDLSAYLKSLTRMKAVPAFDQLDLTSPENNLFGDATAKAKHFTALAQTRSTVTAQLADAELIQAINPLSY
LTTTSSQVAKHWRIRHGAADRDTSFAIPIILAIMLENHGYGIDFALPWDIPHSGDYDLGDLFSWIDGLCQ

The query sequence (length=470) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4j0h:A 470 470 0.9979 0.9979 0.9979 0.0 4j0h:B, 4j0j:A, 4j0j:B, 4j0k:A, 4j0k:B, 4jui:A, 4jui:B, 3wa7:A
2 6yq4:B 480 481 0.4596 0.4500 0.4491 4.26e-141 6yq4:A, 6yq4:C
3 6xyc:A 285 74 0.0574 0.0947 0.3649 0.005
4 7ne7:A 677 171 0.1021 0.0709 0.2807 0.19 7ne4:A, 7ne5:A, 7ob1:A, 7ywp:A
5 6nkf:A 301 56 0.0426 0.0664 0.3571 0.46 6nkf:D
6 7y43:A 79 28 0.0255 0.1519 0.4286 0.79 8h7a:A, 8h7a:B, 8h7a:E, 8h7a:F
7 5aob:A 278 39 0.0298 0.0504 0.3590 1.2 5aoc:A, 7bfr:A
8 1c7i:A 483 60 0.0362 0.0352 0.2833 1.5 1qe3:A
9 6rxx:UV 1061 57 0.0404 0.0179 0.3333 4.0
10 6z1p:AM 126 32 0.0255 0.0952 0.3750 4.1
11 1mje:A 600 38 0.0298 0.0233 0.3684 4.3
12 6sxy:B 340 45 0.0340 0.0471 0.3556 4.3 8pc7:A, 8pc7:B, 8pc7:C, 8pc7:D, 6sxy:A, 6sya:A, 6sya:B, 6syl:A, 6syl:B
13 8iyb:A 275 91 0.0489 0.0836 0.2527 4.7 8iyb:B, 8iyc:A, 8iyc:B
14 1ser:B 421 26 0.0255 0.0285 0.4615 4.8 1ses:A, 1ses:B, 1set:A, 1set:B
15 3err:A 527 26 0.0255 0.0228 0.4615 5.1 3err:B, 1ser:A
16 8j0g:B 274 69 0.0447 0.0766 0.3043 5.3 8j0e:B, 8j0f:C, 8j0f:A, 8j0f:B, 8j0f:D, 8j27:B, 8j28:C, 8y2h:B, 8y2h:F, 8y2h:G, 8y2h:H
17 8axc:B 532 69 0.0426 0.0376 0.2899 5.5 8axc:A, 8axc:C, 8axc:D
18 7aor:ae 574 75 0.0426 0.0348 0.2667 5.6
19 5ydj:B 538 46 0.0340 0.0297 0.3478 5.6 6ary:A, 6ary:B
20 7n4y:B 2455 112 0.0617 0.0118 0.2589 6.5 7n4y:A
21 1xqp:A 252 44 0.0319 0.0595 0.3409 7.0
22 8is4:A 452 84 0.0404 0.0420 0.2262 8.5 8is4:B, 8is5:A, 8is5:B, 7ww2:A, 7ww2:B
23 5hc2:A 343 49 0.0362 0.0496 0.3469 8.7 5hc0:A, 5hc2:B, 5hc2:C, 5hc2:D, 5hc3:B, 5hc3:D, 5hc4:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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