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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SMRVLLAPMEGVLDSLVRELLTEVNDYDLCITEFVRVVDQLLPVKVFHRICPELQNASRTPSGTLVRVQLLGQFPQWLAE
NAARAVELGSWGVDLNCGAPSGSGGGATLLKDPELIYQGAKAMREAVPAHLPVSVKVRLGWDSGEKKFEIADAVQQAGAT
ELVVHGRTKEQGYRAEHIDWQAIGDIRQRLNIPVIANGEIWDWQSAQQCMAISGCDAVMIGRGALNIPNLSRVVKYNEPR
MPWPEVVALLQKYTRLEKQGDTGLYHVARIKQWLSYLRKEYDEATELFQHVRVLNNSPDIARAIQAIDI

The query sequence (length=309) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4bf9:A 318 313 0.9968 0.9686 0.9840 0.0 4bfa:A, 4bfa:B, 4yco:A, 4yco:B, 4yco:C, 4ycp:A
2 3w9z:A 290 308 0.9288 0.9897 0.9318 0.0
3 1vhn:A 305 249 0.2492 0.2525 0.3092 2.85e-24
4 6ei9:A 306 319 0.2848 0.2876 0.2759 2.04e-22 6ei9:B
5 4xp7:A 324 263 0.2362 0.2253 0.2776 1.13e-12 6eza:A, 6eza:B, 6ezb:A, 6ezc:A, 4wfs:A
6 3b0v:C 315 185 0.1877 0.1841 0.3135 4.92e-10 3b0p:A, 3b0p:B, 3b0u:X, 3b0u:Y, 3b0v:D
7 3r11:B 364 140 0.1003 0.0852 0.2214 0.087 3r0u:A, 3r10:A, 3r11:A, 3r1z:A, 3r1z:B
8 1ep3:A 311 155 0.1230 0.1222 0.2452 0.25 1ep1:A, 1ep2:A, 5ksw:A, 5ksw:C, 5ue9:A, 5ue9:C
9 3iiv:B 262 45 0.0421 0.0496 0.2889 0.28 7ac8:A, 7ac8:C, 7ac8:E, 6ct3:A, 5d2t:A, 5d2w:A, 6dc1:A, 6dc1:B, 6dc1:H, 6dc1:K, 6dkv:A, 6dnj:A, 1gpw:C, 1gpw:E, 6rtz:A, 6ru0:A, 6ru0:C, 6ru0:E, 2wjz:A, 2wjz:C
10 3q45:A 368 186 0.1359 0.1141 0.2258 0.28 3q45:B, 3q45:C, 3q45:D, 3q45:E, 3q45:F, 3q45:G, 3q45:H, 3q45:I, 3q4d:A, 3q4d:B, 3q4d:C, 3q4d:D, 3q4d:E, 3q4d:F, 3q4d:G, 3q4d:H, 3q4d:I
11 7l00:C 315 72 0.0712 0.0698 0.3056 0.44 7l00:A, 7l00:B, 7l00:D
12 8pun:A 356 58 0.0615 0.0534 0.3276 0.46 8pun:B, 8pun:C, 8pun:D
13 6nke:A 249 58 0.0518 0.0643 0.2759 0.66
14 8e73:G2 258 82 0.0744 0.0891 0.2805 0.78 6x89:G2
15 8a22:At 253 66 0.0615 0.0751 0.2879 0.80 8apn:At, 8apo:At
16 5k2z:B 278 92 0.0971 0.1079 0.3261 1.4 5k2z:A, 5k2z:C, 5k2z:D, 5lnr:A, 5lnr:B, 5lnr:C, 5lnr:D, 5lns:A, 5lns:B, 5lns:C, 5lns:D, 5lnt:A, 5lnt:B, 5lnt:C, 5lnt:D, 5lnu:A, 5lnu:B, 5lnu:C, 5lnu:D, 5lnv:A, 5lnv:B, 5lnv:C, 5lnv:D, 5lnw:A, 5lnw:B, 5lnw:C, 5lnw:D, 7nhe:A, 7nhe:B, 7nhe:C, 7nhe:D
17 5gvh:A 311 55 0.0550 0.0547 0.3091 1.7
18 4mlz:A 299 73 0.0647 0.0669 0.2740 2.6 4mlz:B
19 1xmv:A 293 176 0.1392 0.1468 0.2443 2.8
20 8adj:A 515 46 0.0485 0.0291 0.3261 3.9 8adj:B, 8adj:C
21 3og2:A 986 125 0.1068 0.0335 0.2640 4.3 3ogr:A, 3ogs:A, 3ogv:A
22 7a8r:A 531 90 0.0647 0.0377 0.2222 4.6 7a8r:B, 6jtz:A, 6jtz:B, 4u7d:A, 4u7d:B, 4u7d:D, 4u7d:C, 2v1x:A, 2v1x:B, 2wwy:B, 2wwy:A, 8yrs:B, 8yrs:A
23 1s20:G 335 84 0.0583 0.0537 0.2143 5.3 1s20:A, 1s20:B, 1s20:C, 1s20:D, 1s20:E, 1s20:F, 1s20:H
24 4e4z:A 312 107 0.0874 0.0865 0.2523 5.5 6ala:A, 6ala:C, 6alv:A, 6amp:A, 6an3:A, 6ao6:A, 6ay0:A, 8dsj:A, 8dsj:K, 8dsl:A, 8dsl:B, 8dsn:A, 8dsn:K, 3mib:A, 3mic:A, 3mid:A, 3mie:A, 3mif:A, 3mig:A, 3mih:A, 3mlj:A, 3mlk:A, 3mll:A, 6nck:A, 1opm:A, 1phm:A, 3phm:A, 1sdw:A, 5wja:A, 5wja:D, 1yi9:A, 1yip:A, 1yjk:A
25 2zbk:B 506 50 0.0518 0.0316 0.3200 5.9 2hkj:A, 1mu5:A, 1mx0:A, 1mx0:B, 1mx0:C, 1mx0:D, 1mx0:E, 1mx0:F, 1z59:A, 1z5a:A, 1z5a:B, 1z5b:A, 1z5b:B, 1z5c:A, 1z5c:B, 2zbk:D, 2zbk:F, 2zbk:H
26 5ocs:A 369 135 0.1036 0.0867 0.2370 6.5 5ocs:C
27 2iop:A 618 94 0.0809 0.0405 0.2660 7.3 2iop:B, 2iop:C, 2iop:D, 2ior:A, 1y4s:A, 1y4s:B
28 8e5h:A 368 39 0.0421 0.0353 0.3333 8.3
29 6am0:A 260 73 0.0680 0.0808 0.2877 9.4 6am0:E, 5lop:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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