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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SMPKDVGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLMERIQLPWDSVGRLE
VGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWMESSSWDGRYAMVVCGDIAVYPSGNARPT
GGAGAVAMLIGPKAPLALERGLRGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDR
PFTLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTNKDLDKALLKASQDMFDKKT
KASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAFSYGSGLAASFFSFRVSQDAAPGSPLDKLVSSTSDLPKR
LASRKCVSPEEFTEIMNQREQFYHKVNFSPPGDTNSLFPGTWYLERVDEQHRRKYARRPV

The query sequence (length=460) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2wya:A 460 460 1.0000 1.0000 1.0000 0.0 2wya:B, 2wya:C, 2wya:D
2 2p8u:A 462 455 0.6739 0.6710 0.6813 0.0 2p8u:B
3 7cqt:A 450 457 0.4652 0.4756 0.4683 3.94e-153 7cqt:B, 7cqt:C, 2fa0:A, 2fa3:A
4 2f9a:A 404 457 0.4435 0.5050 0.4464 7.23e-138
5 5hwo:A 418 461 0.3696 0.4067 0.3688 1.70e-67 5hwp:A, 5hwq:A, 5hwr:A
6 3v4x:A 387 370 0.2391 0.2842 0.2973 1.33e-37 3v4x:B, 3v4x:C, 3v4x:D, 1ysl:B
7 1xpl:A 389 377 0.2391 0.2828 0.2918 5.80e-27 1txt:A, 1txt:B, 1txt:C, 1txt:D, 1xpk:A, 1xpk:B, 1xpk:C, 1xpk:D, 1xpl:B, 1xpl:C, 1xpl:D, 1xpm:A, 1xpm:B, 1xpm:C, 1xpm:D
8 5kp7:A 410 476 0.2630 0.2951 0.2542 1.45e-24 5kp8:A
9 3sqz:A 388 443 0.2261 0.2680 0.2348 3.21e-16
10 6esq:I 347 380 0.1957 0.2594 0.2368 2.93e-09
11 8vda:A 311 274 0.1217 0.1801 0.2044 0.055
12 4bkq:A 415 68 0.0413 0.0458 0.2794 0.27 4bkr:A, 5g2o:A, 5jai:A, 5jam:A, 5jaq:A, 3zu2:A, 3zu3:A, 3zu4:A, 3zu5:A
13 6or5:A 2058 115 0.0652 0.0146 0.2609 1.7
14 5uun:A 286 84 0.0543 0.0874 0.2976 2.0 5uun:B, 5uuo:B, 5uuo:A
15 8dgc:A 2028 172 0.0804 0.0182 0.2151 9.7 8dgc:B, 8dgc:C, 8dgc:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218