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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SMKQQKNSKGSSDFCVKNIKQAEFGRREIEIAEQEMPALMALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLGALGAQ
CRWAACNIYSTLNEVAAALAESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKKYPNMFKKIKGI
VEESVTGVHRLYQLAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDMMFGGKQVVVCGYGEVGKGCCAALKAM
GSIVYVTEIDPICALQACMDGFRLVKLNEVIRQVDIVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPE
LTWERVRSQVDHVIWPDGKRIVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVA
SLHLPTFDAHLTELTDEQAKYLGLNKNGPFKPN

The query sequence (length=433) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3gvp:A 433 433 1.0000 1.0000 1.0000 0.0 3gvp:B, 3gvp:C, 3gvp:D, 3mtg:A, 3mtg:B
2 3d64:A 462 460 0.5289 0.4957 0.4978 2.14e-158 3d64:B, 3glq:A, 3glq:B
3 3h9u:C 435 433 0.5242 0.5218 0.5242 1.61e-154 3h9u:A, 3h9u:B, 3h9u:D
4 6aph:A 432 426 0.5219 0.5231 0.5305 5.38e-153
5 1a7a:A 431 423 0.4919 0.4942 0.5035 3.76e-150 1a7a:B, 5axa:A, 5axa:C, 5axb:A, 5axb:C, 5axc:A, 5axc:C, 5axd:A, 5axd:C, 1b3r:A, 1b3r:B, 1b3r:C, 1b3r:D, 8cod:A, 8cod:B, 1d4f:A, 1d4f:B, 1d4f:C, 1d4f:D, 2h5l:A, 2h5l:B, 2h5l:C, 2h5l:D, 2h5l:E, 2h5l:F, 2h5l:G, 2h5l:H, 1k0u:A, 1k0u:B, 1k0u:C, 1k0u:D, 1k0u:E, 1k0u:F, 1k0u:G, 1k0u:H, 1ky4:A, 1ky4:B, 1ky4:C, 1ky4:D, 1ky5:A, 1ky5:B, 1ky5:C, 1ky5:D, 1li4:A, 3nj4:A, 3nj4:B, 3nj4:C, 3nj4:D, 4pfj:A, 4pfj:B, 4pgf:A, 4pgf:B, 5w49:A, 5w49:B, 5w4b:A, 5w4b:B, 5w4b:C, 5w4b:D, 5w4b:E, 5w4b:F, 1xwf:A, 1xwf:B, 1xwf:C, 1xwf:D, 4yvf:A, 4yvf:B
6 3n58:B 461 457 0.5289 0.4967 0.5011 9.31e-147 3n58:A, 3n58:C, 3n58:D
7 3g1u:C 424 431 0.5058 0.5165 0.5081 4.17e-145 3g1u:A, 3g1u:B, 3g1u:D
8 5m5k:C 471 469 0.5058 0.4650 0.4670 1.06e-144 6exi:A, 6exi:B, 6exi:C, 6exi:D, 4lvc:A, 4lvc:B, 4lvc:C, 4lvc:D, 5m5k:A, 5m5k:B, 5m5k:D, 5m65:A, 5m65:B, 5m66:A, 5m66:B, 5m66:C, 5m66:D, 5m67:A, 5m67:B, 5m67:C, 5m67:D
9 6gbn:B 435 422 0.4896 0.4874 0.5024 5.54e-143 6gbn:A, 6gbn:C, 6gbn:D
10 3ond:B 488 476 0.5081 0.4508 0.4622 2.31e-141 3ond:A, 3one:A, 3one:B, 3onf:A, 3onf:B
11 6uk3:A 475 474 0.4942 0.4505 0.4515 3.93e-141 6uk3:C, 6uk3:B, 6uk3:D
12 5v96:A 467 462 0.5012 0.4647 0.4697 2.41e-140 5v96:B, 5v96:C, 5v96:D
13 3ce6:A 486 476 0.4965 0.4424 0.4517 1.10e-138 3ce6:B, 3ce6:C, 3ce6:D, 3dhy:A, 3dhy:B, 3dhy:C, 3dhy:D, 2ziz:A, 2ziz:B, 2ziz:C, 2ziz:D, 2zj0:A, 2zj0:B, 2zj0:C, 2zj0:D, 2zj1:A, 2zj1:B, 2zj1:C, 2zj1:D
14 8cfu:A 467 459 0.5035 0.4668 0.4749 8.30e-138 8ajs:AAA, 8ajs:DDD, 8ajs:BBB, 8ajs:CCC, 8ajt:AAA, 8ajt:DDD, 8ajt:BBB, 8ajt:CCC, 8aju:AAA, 8aju:CCC, 8ajv:AAA, 8ajv:DDD, 8ajv:BBB, 8ajv:CCC, 8ajv:FFF, 8ajv:III, 8ajv:GGG, 8ajv:HHH, 8ajw:AAA, 8ajw:DDD, 8ajw:BBB, 8ajw:CCC, 8azf:A, 8azf:C, 8cfb:A, 8cfb:D, 8cfb:B, 8cfb:C, 8cfc:A, 8cfc:D, 8cfc:B, 8cfc:C, 8cfd:A, 8cfd:D, 8cfd:B, 8cfd:C, 8cfe:A, 8cfe:D, 8cfe:B, 8cfe:C, 8cfg:A, 8cfg:D, 8cfg:B, 8cfg:C, 8cfh:A, 8cfh:D, 8cfh:B, 8cfh:C, 8cfi:A, 8cfi:D, 8cfi:B, 8cfi:C, 8cfj:A, 8cfj:D, 8cfj:B, 8cfj:C, 8cfk:A, 8cfk:D, 8cfk:B, 8cfk:C, 8cfl:A, 8cfl:D, 8cfl:B, 8cfl:C, 8cfm:A, 8cfm:D, 8cfm:B, 8cfm:C, 8cfn:A, 8cfn:C, 8cfo:A, 8cfo:D, 8cfo:B, 8cfo:C, 8cfp:A, 8cfp:D, 8cfp:B, 8cfp:C, 8cfq:A, 8cfq:D, 8cfq:B, 8cfq:C, 8cfr:A, 8cfr:D, 8cfr:B, 8cfr:C, 8cfs:A, 8cfs:D, 8cfs:B, 8cfs:C, 8cft:A, 8cft:D, 8cft:B, 8cft:C, 8cfu:D, 8cfu:B, 8cfu:C, 8cfv:A, 8cfv:D, 8cfv:B, 8cfv:C, 8cfw:A, 8cfw:D, 8cfw:B, 8cfw:C, 8cfx:A, 8cfx:D, 8cfx:B, 8cfx:C, 8cfx:G, 8cfx:J, 8cfx:H, 8cfx:I, 8cfy:A, 8cfy:D, 8cfy:B, 8cfy:C, 8cfy:G, 8cfy:J, 8cfy:H, 8cfy:I, 8cfz:A, 8cfz:D, 8cfz:B, 8cfz:C, 8cfz:H, 8cfz:K, 8cfz:I, 8cfz:J, 8cg0:A, 8cg0:D, 8cg0:B, 8cg0:C, 8cg1:A, 8cg1:D, 8cg1:B, 8cg1:C, 8cg1:G, 8cg1:J, 8cg1:H, 8cg1:I, 8cg2:A, 8cg2:C, 6f3m:A, 6f3m:B, 6f3m:C, 6f3m:D, 6f3n:A, 6f3n:B, 6f3n:C, 6f3n:D, 6f3o:A, 6f3o:B, 6f3o:C, 6f3o:D, 6f3p:A, 6f3p:C, 6f3q:A, 6f3q:B, 6f3q:C, 6f3q:D, 7zd0:A, 7zd0:D, 7zd0:B, 7zd0:C, 7zd1:A, 7zd1:D, 7zd1:B, 7zd1:C, 7zd2:A, 7zd2:D, 7zd2:B, 7zd2:C, 7zd3:A, 7zd3:D, 7zd3:B, 7zd3:C, 7zd4:A, 7zd4:D, 7zd4:B, 7zd4:C
15 1v8b:A 476 468 0.4827 0.4391 0.4466 6.68e-137 1v8b:B, 1v8b:C, 1v8b:D
16 5jpi:A 496 486 0.4642 0.4052 0.4136 6.80e-117 5hm8:A, 5hm8:B, 5hm8:C, 5hm8:D, 5hm8:E, 5hm8:F, 5hm8:G, 5hm8:H, 5jpi:B, 5jpi:C, 5jpi:D, 5jxw:A, 5jxw:B, 5jxw:C, 5jxw:D, 5t8k:A, 5t8k:C, 5t8k:B, 5t8k:D, 5tj9:A, 5tj9:B, 5tj9:C, 5tj9:D, 5tls:A, 5tls:B, 5tls:C, 5tls:D, 5utu:A, 5utu:B, 5utu:C, 5utu:D, 5utu:E, 5utu:F, 5utu:G, 5utu:H
17 7r39:A 412 410 0.3949 0.4150 0.4171 7.74e-102 7r39:B, 7r39:C, 7r39:D, 7r39:E, 7r39:F, 7r39:G, 7r39:H
18 8qno:A 421 413 0.3580 0.3682 0.3753 2.34e-89 8qno:B, 7r37:A, 7r37:B, 7r38:A, 7r38:B
19 7o5l:A 417 413 0.3788 0.3933 0.3971 1.64e-88 7o5l:C, 7o5m:A, 7o5m:C, 7zd7:A, 7zd7:C, 7zd8:A, 7zd8:C, 7zd9:A, 7zd9:C
20 7r3a:A 411 410 0.3441 0.3625 0.3634 1.60e-83 7r3a:B, 7r3a:C, 7r3a:D, 7r3a:E, 7r3a:F, 7r3a:G, 7r3a:H
21 3x2f:A 406 401 0.3279 0.3498 0.3541 4.61e-76 5tov:B, 5tow:B, 3x2e:A, 3x2e:B, 3x2e:C, 3x2e:D, 3x2f:B
22 6bul:B 327 64 0.0485 0.0642 0.3281 0.14 6aqj:A, 6aqj:B, 6bul:A, 6c55:A, 6c55:B, 6c5n:A, 6c5n:B, 7ke2:B, 7ke2:A, 7kh7:A, 7kh7:B, 6vo2:A, 6vo2:B, 5w3k:A, 5w3k:B
23 5yeq:B 329 83 0.0600 0.0790 0.3133 0.19
24 4cjx:A 297 114 0.0624 0.0909 0.2368 0.31 4cjx:B
25 2ekl:A 312 104 0.0508 0.0705 0.2115 0.83
26 4tsk:A 333 60 0.0370 0.0480 0.2667 1.4
27 6d4b:A 361 75 0.0462 0.0554 0.2667 1.9 6d4b:B, 6d4c:A, 6d4c:B, 5dn9:A, 5dn9:B
28 4azq:A 136 92 0.0577 0.1838 0.2717 2.4 4azp:A
29 5vj7:A 462 91 0.0647 0.0606 0.3077 2.5
30 3ip4:B 482 41 0.0346 0.0311 0.3659 2.5 2df4:B, 2dqn:B, 2f2a:B, 2g5h:B, 2g5i:B
31 2ifc:C 382 99 0.0693 0.0785 0.3030 2.7 2ifc:A, 2ifc:B, 2ifc:D, 2r26:A, 2r26:B, 2r26:C, 2r26:D, 2r9e:A, 2r9e:B, 2r9e:C, 2r9e:D, 4ybo:B, 4ybo:C
32 6jcz:C 331 61 0.0370 0.0483 0.2623 2.9 6jcw:A, 6jcw:B, 6jcw:C, 6jcw:D, 6jcw:E, 6jcw:F, 6jcw:G, 6jcw:H, 6jcw:I, 6jcw:J, 6jcw:K, 6jcw:L, 6jcz:A, 6jcz:B, 6jcz:D, 6jcz:E, 6jcz:F, 6jcz:G, 6jcz:H, 6jcz:I, 6jcz:J, 6jcz:K, 6jcz:L, 6jd1:A, 6jd1:B, 6jd1:C, 6jd1:D, 6jd1:E, 6jd1:F, 6jd1:G, 6jd1:H, 6jd1:I, 6jd1:J, 6jd1:K, 6jd1:L, 6jd2:A, 6jd2:B, 6jd2:C, 6jd2:D, 6jd2:E, 6jd2:F, 6jd2:G, 6jd2:H, 6jd2:I, 6jd2:J, 6jd2:K, 6jd2:L, 6kou:A, 6kou:B, 6kou:C, 6kou:D, 6kou:E, 6kou:F, 6kou:G, 6kou:H, 6kou:I, 6kou:J, 6kou:K, 6kou:L, 6kpa:A, 6kpa:B, 6kpa:C, 6kpa:D, 6kpa:E, 6kpa:F, 6kpa:G, 6kpa:H, 6kpa:I, 6kpa:J, 6kpa:K, 6kpa:L, 6kph:A, 6kph:B, 6kph:C, 6kph:D, 6kph:E, 6kph:F, 6kph:G, 6kph:H, 6kph:I, 6kph:J, 6kph:K, 6kph:L, 6kpi:A, 6kpi:B, 6kpi:C, 6kpi:D, 6kpi:E, 6kpi:F, 6kpi:G, 6kpi:H, 6kpi:I, 6kpi:J, 6kpi:K, 6kpi:L, 6kpj:A, 6kpj:B, 6kpj:C, 6kpj:D, 6kpj:E, 6kpj:F, 6kpj:G, 6kpj:H, 6kpj:I, 6kpj:J, 6kpj:K, 6kpj:L, 6kq4:A, 6kq4:B, 6kq4:C, 6kq4:D, 6kq4:E, 6kq4:F, 6kq4:G, 6kq4:H, 6kq4:I, 6kq4:J, 6kq4:K, 6kq4:L, 6kqj:A, 6kqj:B, 6kqj:C, 6kqj:D, 6kqj:E, 6kqj:F, 6kqj:G, 6kqj:H, 6kqj:I, 6kqj:J, 6kqj:K, 6kqj:L, 6kqk:A, 6kqk:B, 6kqk:C, 6kqk:D, 6kqk:E, 6kqk:F, 6kqk:G, 6kqk:H, 6kqk:I, 6kqk:J, 6kqk:K, 6kqk:L, 6kqo:A, 6kqo:B, 6kqo:C, 6kqo:D, 6kqo:E, 6kqo:F, 6kqo:G, 6kqo:H, 6kqo:I, 6kqo:J, 6kqo:K, 6kqo:L
33 7koe:A 282 79 0.0531 0.0816 0.2911 3.8 7koe:E
34 5o6m:D 264 105 0.0624 0.1023 0.2571 4.2 5lc9:B, 5lc9:C, 5lc9:D, 5lcd:A, 5lcd:B, 5lcd:C, 5lcd:D, 5ld1:A, 5ld1:D, 5ld1:B, 5ld1:C, 5ldb:A, 5ldb:B, 5ldb:C, 5ldb:D, 5maq:A, 5maq:B, 5maq:C, 5maq:D, 5o6k:A, 5o6k:B, 5o6k:C, 5o6k:D, 5o6m:A, 5o6m:B, 5o6m:C
35 6qhe:A 261 133 0.0808 0.1341 0.2632 4.4 6qhe:B, 6qhe:C, 6qhe:D, 6qhe:F
36 2p9e:A 406 103 0.0508 0.0542 0.2136 6.0 2p9c:A, 2p9c:B, 2p9e:B, 2p9e:C, 2p9e:D, 2p9g:A, 2p9g:B, 2pa3:A, 1psd:A, 1psd:B, 1sc6:A, 1sc6:B, 1yba:A, 1yba:B, 1yba:C, 1yba:D
37 1hfe:L 396 74 0.0531 0.0581 0.3108 6.4 8bj7:A, 8bj8:A, 1e08:A, 1gx7:A, 1hfe:M, 6sg2:AAA
38 1sc6:D 384 103 0.0508 0.0573 0.2136 7.6 1sc6:C
39 5och:C 537 64 0.0531 0.0428 0.3594 7.7
40 3ulk:A 489 74 0.0508 0.0450 0.2973 7.9 3ulk:B
41 5jca:L 471 91 0.0624 0.0573 0.2967 9.2 5jfc:L
42 5och:E 576 64 0.0531 0.0399 0.3594 9.4 7ehl:A, 7ehl:B, 5och:A, 5och:B, 5och:D, 5och:F, 5och:G, 5och:H

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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