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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SMKAIVVINLVKINKKIIPDKIYVYRLYSIYRLAYENVGIVIDPENLIIATTKELEYEGEFIPEGEISFSELRNDYQSKL
VLRLLKENGIGEYELSKLLRKFRKPKTFGDYKVIPSVEMSVIKHDEDFYLVIHIIHQIQSMKTLWELVNKDPKELEEFLM
THKENLMLKDIASPLKTVYKPCFEEYTKKPKLDHNQEIVKYWYNYHIERYWNTPEAKLEFYRKFGQVDLKQPAILAKFAS
KNYKIYLLPQLVVPTYNAEQLAKEILEYTKLMPEERKELLENILAEVDSDIIDKSLSEIEVEKIAQELENKIRVRDDKGN
SVPISQLLWTNYSRKYPVILPYEVPEKFRKIREIPMFIILDSGLLADIQNFATNEFRELVKSMYYSLAKKYKEKVITEDL
NSDKGIIEVVEQVSSFMKGKELGLAFIAARNKLSSEKFEEIKRRLFNLNVISQVVNEDTLKNKRDKYDRNRLDLFVRHNL
LFQVLSKLGVKYYVLDYRFNYDYIIGIDVAPMKRSEGYIGGSAVMFDSQGYIRKIVPIKIGEQRGESVDMNEFFKEMVDK
FKEFNIKLDNKKILLLRDGRITNNEEEGLKYISEMFDIEVVTMDVIKNHPVRAFANMKMYFNLGGAIYLIPHKLKQAKGT
PIPIKLAKKRIIKNGKVEKQSITRQDVLDIFILTRLNYGSIRLPAPVHYAHKFANAIRNEWKIKEEFLAEGFLYFV

The query sequence (length=716) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1z26:A 716 716 1.0000 1.0000 1.0000 0.0 1z25:A
2 8jpx:B 770 770 0.9986 0.9286 0.9286 0.0 8jpx:A
3 8wd8:A 750 748 0.5628 0.5373 0.5388 0.0 8jsi:A, 8jsi:B, 8wd8:B
4 5g5s:A 692 763 0.3031 0.3136 0.2844 1.49e-56 5g5t:A
5 2f8s:A 704 270 0.1061 0.1080 0.2815 3.74e-10 2f8t:A
6 1yvu:A 682 270 0.1061 0.1114 0.2815 3.87e-10
7 4n76:A 641 293 0.0950 0.1061 0.2321 4.02e-06 5gq9:A, 3hxm:A
8 3hvr:A 660 293 0.0978 0.1061 0.2389 4.14e-06 3hm9:A, 3hvr:B
9 5xow:A 684 293 0.0936 0.0980 0.2287 1.17e-05 3dlb:A, 3dlb:B, 3dlh:A, 3dlh:B, 3f73:A, 3f73:B, 5gq9:B, 3hjf:A, 3hk2:A, 3hk2:B, 3ho1:A, 4kpy:A, 4kpy:B, 4n41:A, 4n41:B, 4n47:A, 4n76:B, 4nca:A, 4nca:B, 4ncb:A, 4ncb:B, 5xp8:A, 5xpa:A, 5xpg:A, 5xq2:A, 5xq2:B
10 5xou:B 574 293 0.0936 0.1167 0.2287 1.36e-05 5xou:A
11 8ok9:A 430 434 0.1439 0.2395 0.2373 0.011 2bgg:A, 8pvv:A, 8qg0:A, 6t5t:A, 6tuo:A, 2w42:A, 6xu0:A, 6xu0:B, 6xup:A, 6xup:B, 1ytu:A, 1ytu:B
12 8r3z:A 755 73 0.0391 0.0371 0.3836 0.057
13 2bgg:B 394 250 0.0922 0.1675 0.2640 0.14 2w42:B
14 7yfx:A 746 279 0.0992 0.0952 0.2545 0.24 7yfy:A, 7ygn:A
15 5ux0:D 639 209 0.0698 0.0782 0.2392 0.26 5i4a:A, 5i4a:C, 5ux0:A
16 7w3u:A 343 48 0.0265 0.0554 0.3958 0.54 7w3r:A, 7w3u:B, 7w3u:C
17 7kx9:A 734 251 0.0782 0.0763 0.2231 0.60 7kx7:A, 7yfq:A, 7yg6:A
18 4mlm:A 188 45 0.0251 0.0957 0.4000 0.61 4mlm:B, 4mln:A, 4mln:B, 4n6w:A, 4n71:A, 4n71:B, 4n71:D, 4n71:E
19 2og1:A 285 90 0.0279 0.0702 0.2222 1.1 2puh:A, 2puj:A, 2rht:A, 2rhw:A, 3v1m:A, 3v1n:A
20 7ane:d 343 31 0.0182 0.0379 0.4194 1.4
21 8qog:B 500 125 0.0419 0.0600 0.2400 2.4 8iaj:A, 8iaj:E, 8iak:A, 8iak:E, 8qof:F, 8qof:B
22 6z2w:E 2325 65 0.0237 0.0073 0.2615 3.4 6z2w:F, 6z2x:E, 6z2x:F, 6z3a:F, 6z3a:E
23 3ux3:A 130 50 0.0209 0.1154 0.3000 3.8 3ux3:B
24 6kr6:A 713 429 0.1173 0.1178 0.1958 4.9
25 4kuj:B 268 100 0.0293 0.0784 0.2100 5.0 4kuj:A, 4nl0:A, 4nl0:B
26 3pt6:B 915 70 0.0293 0.0230 0.3000 5.5 4da4:A, 3pt6:A, 6w8v:A
27 2zyr:A 464 184 0.0573 0.0884 0.2228 5.8 2zyh:A, 2zyh:B, 2zyi:A, 2zyi:B, 2zyr:B
28 4pbg:A 468 80 0.0321 0.0491 0.2875 5.9 4pbg:B
29 6e6k:A 134 65 0.0293 0.1567 0.3231 7.7
30 4p4s:B 336 31 0.0182 0.0387 0.4194 9.2 4p4s:A, 4p4t:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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