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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SMIRKQAESYANSTWEVLQYKDSGEPGVLEVFVTINGKVQNITFHIPKTIYMKFKSQTMPLQKIKNCLIEKSSASLPNNP
KTSNPESVFLEEKENCTSIFNDENVLGVFEGTITPHQRAIMLSMAENERYLSGFSMDIGYLLHFPTSIGYEFFSLFKSWG
DTITILVLKPSNQAQEINASSLGQIYKQMFEKKKGKIETYSYLVDIKEDINFEFVYFTDISKLYRRLSQETTKLKEERGL
QFLLLLQSPFITKLLGTIRLLNQMPIVKLSLNEVLLPQLNWQPTLLKKLVNHVLSSGSWISHLIKLSQYSNIPICNLRLD
SMDYIIDVLYARKLKKENIVLWWNEKAPLPDHGGIQNWIMNDSEFPKINNSGVYDNVVLDVGVDNLTVNTILTSSNDALN
VLRGMLKEWWDEALKENSTADLLVNSLASWVQNPNAKLFDGLLRYHVHNLTKKALLQLVNEFSALGSTIVYADRNQILIK
TNKYSPENCYAYSQYMMKAVRTNPMFSYLDLNIKRYWDLLIWMDKFNFSGLACIEIEEKENQDYTAVSQWQLKKFLSPIY
QPEFEDWMMIILDSMLKTKQSYLKLNKEDSVENSLNGFSHLFSKPLMKRVKKLFKNQQEFILDPQYEASHLNVKNPLLEL
VKSLCHVMLLSKSTILEISLVVPDFLCEYCFFISDIDFCKFSCVRCHKAFNQVLLQEHLIQKLRSDIESYLIQDLRCSRC
HKVKRDYMSAHCPCAGAWEGTLPRESIVQKLNVFKQVAKYYGFDILLSCIADLT

The query sequence (length=774) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6hv8:A 774 774 1.0000 1.0000 1.0000 0.0 6hv9:A
2 8kg9:M 812 817 0.9716 0.9261 0.9204 0.0
3 8xgc:8 857 858 0.9767 0.8821 0.8811 0.0
4 8p5e:G 825 852 0.9470 0.8885 0.8603 0.0 8kg6:M, 8kg8:M, 8p62:G, 8p63:G
5 7pmk:Q 766 823 0.8915 0.9008 0.8384 0.0 7pmn:Q
6 7qhs:G 756 828 0.8450 0.8651 0.7899 0.0 7z13:N, 7z13:Q
7 7pfo:B 759 323 0.1163 0.1186 0.2786 4.92e-28 7plo:B, 5vbn:B, 5vbn:F
8 7pfo:B 759 213 0.0672 0.0685 0.2441 1.72e-17 7plo:B, 5vbn:B, 5vbn:F
9 8ppt:B 1191 70 0.0284 0.0185 0.3143 0.002 8ppu:B, 8ppv:B, 6t8h:B
10 6knb:B 1120 72 0.0258 0.0179 0.2778 0.007 6knc:B
11 8bx8:C 3947 123 0.0401 0.0079 0.2520 0.12 7k58:C, 7k5b:C, 7kek:C
12 7ej6:B 316 78 0.0284 0.0696 0.2821 0.85 7ej6:C, 7ej6:A, 7ej7:B, 7ej7:A, 7ej7:C
13 1tyg:A 242 88 0.0271 0.0868 0.2386 1.5 1tyg:C
14 6fop:A 717 70 0.0245 0.0265 0.2714 2.0
15 5w0n:A 379 33 0.0116 0.0237 0.2727 2.1 5w0m:A, 5w0m:C, 5w0n:B
16 5w0b:A 334 33 0.0116 0.0269 0.2727 2.4
17 1z45:A 674 164 0.0491 0.0564 0.2317 2.9
18 8opp:A 670 33 0.0116 0.0134 0.2727 3.1
19 6s60:B 214 129 0.0426 0.1542 0.2558 3.7 6cdy:A, 6cdy:B, 8cuh:A, 8cuh:B, 5dq8:A, 5dq8:B, 5dqe:A, 5dqe:B, 8e1o:A, 8e1o:B, 6e5g:B, 6e5g:A, 7oyj:B, 8p29:A, 8poj:A, 8pom:B, 8pom:A, 8pon:A, 8pux:A, 8puy:B, 6s64:B, 6s66:B, 6s69:B, 6s6j:B, 7t2j:B, 7t2j:A, 7t2k:B, 7t2k:A, 7t2l:A, 7t2m:B, 7typ:A, 7typ:B, 7tyq:A, 7tyq:B, 7tyu:A, 7tyu:B, 6uyb:A, 6uyb:B, 6uyc:A, 6uyc:B, 6vah:A, 6vah:B
20 8opt:A 783 33 0.0116 0.0115 0.2727 3.7 8ops:A, 5w0m:B, 5w0n:C, 5w0o:A, 5w0o:B
21 3ie7:A 309 57 0.0233 0.0583 0.3158 3.8 3jul:A
22 4ihc:B 395 73 0.0233 0.0456 0.2466 5.0 4ihc:C, 4ihc:D, 4ihc:E, 4ihc:F, 4ihc:H
23 1t10:A 556 52 0.0207 0.0288 0.3077 5.6
24 8t78:A 863 177 0.0517 0.0463 0.2260 9.6

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218