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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SMDVFWFLPTHGDGHYLGTTQGARPVTLNYLKQVAQAADSLGYHGVLIPTGRSCEDSWVIASALVPLTERLRYLVAIRPG
IISPTVSARMAATLDRLSNGRLLINVVTGGDPDENRGDGSFLSHSERYEVTDEFLKIWRRVLQGEAVDFEGKHLKVQNAK
ALYPPVQKPYPPLYFGGSSDAAHDLAAEQVDVYLTWGEPPAAVAEKLADVRERAARHGRKVKFGIRLHVIVRETAEEAWK
AADKLIEHISDETIEAAQKSFSRFDSEGQRRMAALHDGRRDNLEIAPNLWAGVGLVRGGSGTALVGDPQQVAARIKEYAD
LGIESFIFSGYPHLEEAYRFAELVFPLLPEPYASLAGRGVTNLTGPFGEMIANDVLPA

The query sequence (length=378) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7jw9:A 378 378 1.0000 1.0000 1.0000 0.0 7jw9:B, 7jw9:C, 7jw9:D, 7jyb:A, 7jyb:C, 7jyb:E, 7k14:A, 7k14:B, 7k14:C, 7k14:D, 7k14:E, 7k14:G, 7k64:A, 7k64:C, 7k64:E
2 7k64:H 348 378 0.9206 1.0000 0.9206 0.0 7jyb:B, 7jyb:D, 7jyb:G, 7k14:H, 7k64:D, 7k64:G
3 3b9o:A 433 341 0.2275 0.1986 0.2522 3.32e-16 3b9o:B
4 5wan:A 341 192 0.1402 0.1554 0.2760 4.11e-13 6sgg:AAA, 6sgl:AAA, 6sgm:AAA, 6sgn:AAA, 6tee:AAA, 6tef:AAA, 6teg:AAA
5 5w4y:A 450 384 0.2275 0.1911 0.2240 1.54e-12 5w4y:B, 5w4z:A, 5w4z:B
6 1yw1:A 393 388 0.2646 0.2545 0.2577 7.84e-11
7 6asl:A 430 300 0.2063 0.1814 0.2600 1.30e-10
8 7cza:A 419 238 0.1614 0.1456 0.2563 1.91e-09 7cza:B
9 5xkd:A 445 156 0.1270 0.1079 0.3077 1.61e-08 5xkd:B, 5xkd:C, 5xkd:D
10 8qpl:A 331 176 0.1190 0.1360 0.2557 5.41e-08 8qpl:B
11 1rhc:A 330 216 0.1323 0.1515 0.2315 0.004
12 3b4y:A 332 143 0.1085 0.1235 0.2867 0.013 3b4y:B
13 1ezw:A 347 166 0.1005 0.1095 0.2289 0.058
14 5gky:A 3660 73 0.0529 0.0055 0.2740 0.29 5gky:C, 5gky:E, 5gky:G, 5gkz:A, 5gkz:C, 5gkz:E, 5gkz:G, 5gl0:A, 5gl0:C, 5gl0:E, 5gl0:G, 5gl1:A, 5gl1:C, 5gl1:E, 5gl1:G
15 3aw5:A 438 103 0.0608 0.0525 0.2233 0.49 6k3d:A, 8p4g:A, 8p4g:B
16 6fxh:A 481 178 0.1164 0.0915 0.2472 0.82 5cqz:A, 5cqz:B, 5cr7:A, 5cr7:B, 6ddb:A, 6ddb:B, 6ddc:A, 6ddc:B, 6ddh:A, 6ddz:A, 6de2:A, 6de3:A, 6fir:A, 6fis:A, 6fiu:A, 6fiw:A, 4h4b:A, 2j2c:A, 2jc9:A, 2jcm:A, 5opk:A, 5opl:A, 5opm:A, 5opo:A, 2xcv:A, 2xcw:A, 2xjb:A, 2xjc:A, 2xjd:A, 2xje:A, 2xjf:A
17 3dzd:A 368 49 0.0370 0.0380 0.2857 1.7 3dzd:B
18 2qed:A 252 95 0.0556 0.0833 0.2211 1.8
19 8s65:B 411 87 0.0767 0.0706 0.3333 2.4 8s65:A
20 8k49:T 627 42 0.0317 0.0191 0.2857 3.6 8k42:R, 8k42:S, 8k42:T, 8k42:U, 8k42:V, 8k42:W, 8k49:R, 8k49:S, 8w9p:R, 8w9p:S, 8w9p:T, 8w9p:U, 8w9p:V, 8w9p:W, 8w9q:R, 8w9q:S, 8w9q:T
21 7bip:B 329 146 0.1032 0.1185 0.2671 4.2
22 8v4a:A 466 44 0.0344 0.0279 0.2955 4.4 9bnj:A, 9bnj:B, 9bnj:C, 9bnj:D, 8v2k:A, 8v2k:B, 8v2k:C, 8v2k:D, 8v4a:B, 8v4a:C, 8v4a:D, 8v6p:A, 8v6p:B, 8v6p:C, 8v6p:D, 8v9p:A, 8v9p:B, 8v9p:C, 8v9p:D, 5w19:A, 5w19:B, 5w19:C, 5w19:D
23 7q03:A 328 64 0.0503 0.0579 0.2969 5.7 7q07:A
24 3fcp:A 356 107 0.0794 0.0843 0.2804 6.9 3fcp:B, 3fcp:C, 3fcp:D, 3fcp:E, 3fcp:F, 3fcp:G, 3fcp:H

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218