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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SMAFPKRLEYGGHALVWSGDWSAAGARKAIAGAARAGYDYIEIALLDPWQIDVALTKDLLQEYNLRAHASLGLSAATDVT
STDPAIVAKGDELLRKATDVLYALGGSELCGVIYCALGKYPGPASRENRANSVAAMQRLADYAADKGINIDLEVVNRYET
NIMNTGLEGLAFLDEVNRPNAFLHLDTYHMNIEENGMAKSVLAAGDRLGYVHIGESHRGYLGTGNVDFASFFAALKQIDY
RGPITFESFSSEIVDPKLSNTLCVWRNLWHDSDDLAGKALEFIKQRY

The query sequence (length=287) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7cj5:A 292 285 0.9930 0.9760 1.0000 0.0 7cj4:A, 7cj4:B, 7cj5:B, 7cj6:A, 7cj6:B, 7cj7:A, 7cj7:B, 7cj8:A, 7cj8:B, 7cj8:C, 7cj8:D, 7cj8:E, 7cj8:F, 7cj9:A, 7cj9:B, 7cj9:C, 7cj9:D, 7cj9:E, 7cj9:F, 7cj9:G, 7cj9:H
2 5zfs:B 294 279 0.5331 0.5204 0.5484 6.28e-109 5zfs:A
3 3vyl:A 297 273 0.3972 0.3838 0.4176 1.04e-74 3vyl:B, 3vyl:C, 3vyl:D, 3vyl:E, 3vyl:F, 3vyl:G, 3vyl:H
4 7ern:C 284 278 0.3554 0.3592 0.3669 5.64e-56 7erm:A, 7erm:B, 7erm:C, 7erm:D, 7ern:A, 7ern:B, 7ern:D, 7ero:A, 7ero:B, 7ero:C, 7ero:D
5 7dz4:C 286 279 0.3519 0.3531 0.3620 2.61e-55 7dz2:A, 7dz2:B, 7dz2:C, 7dz2:D, 7dz3:A, 7dz3:B, 7dz3:C, 7dz3:D, 7dz4:A, 7dz4:B, 7dz4:D, 7dz5:A, 7dz5:B, 7dz5:C, 7dz5:D, 7dz6:A, 7dz6:B, 7dz6:C, 7dz6:D
6 4pfh:A 298 283 0.3101 0.2987 0.3145 4.42e-39 5j8l:A, 5j8l:B, 5j8l:C, 5j8l:D, 2ou4:A, 2ou4:B, 2ou4:C, 2ou4:D, 4pfh:B, 4pgl:A, 4pgl:B, 4pgl:C, 4pgl:D, 4q7i:A, 4q7i:B, 2qul:A, 2qul:B, 2qul:C, 2qul:D, 2qum:A, 2qum:B, 2qum:C, 2qum:D, 2qun:A, 2qun:B, 2qun:C, 2qun:D, 4xsl:A, 4xsl:B, 4xsl:C, 4xsl:D, 4xsm:A, 4xsm:B, 4xsm:C, 4xsm:D, 4ytq:A, 4ytq:B, 4ytq:C, 4ytq:D, 4ytr:A, 4ytr:B, 4ytr:C, 4ytr:D, 4yts:A, 4yts:B, 4yts:C, 4yts:D, 4ytt:A, 4ytt:B, 4ytt:C, 4ytt:D, 4ytu:A, 4ytu:B, 4ytu:C, 4ytu:D
7 2hk1:A 289 266 0.2718 0.2699 0.2932 1.32e-32 2hk1:B, 2hk1:C, 2hk1:D
8 3vnl:A 291 272 0.2578 0.2543 0.2721 6.41e-27 7e9w:A, 7e9w:B, 7e9w:C, 7e9w:D, 3vni:A, 3vni:B, 3vni:C, 3vni:D, 3vnj:A, 3vnj:B, 3vnj:C, 3vnj:D, 3vnk:A, 3vnk:B, 3vnk:C, 3vnk:D, 3vnl:B, 3vnl:C, 3vnl:D, 3vnm:A, 3vnm:B, 3vnm:C, 3vnm:D
9 7x7w:A 288 290 0.2892 0.2882 0.2862 8.79e-27 7x7w:B
10 5h1w:A 270 244 0.2718 0.2889 0.3197 3.60e-26 5b7y:A, 5b7y:B, 5b80:A, 5b80:B, 5h1w:B, 5h6h:A, 5h6h:B
11 6wn6:B 264 223 0.2091 0.2273 0.2691 1.95e-15 6wn6:A, 6wn6:C, 6wn6:D
12 2qw5:A 327 230 0.1986 0.1743 0.2478 1.17e-12 2qw5:B
13 1i6n:A 278 234 0.1951 0.2014 0.2393 5.44e-09
14 3kws:A 265 176 0.1568 0.1698 0.2557 7.54e-09 3kws:B
15 3cqj:A 276 182 0.1638 0.1703 0.2582 3.44e-07 3cqj:B, 3cqk:A, 3cqk:B
16 3ngf:B 260 213 0.1568 0.1731 0.2113 5.14e-06 3ngf:A
17 3tva:A 282 152 0.1429 0.1454 0.2697 1.89e-05 3tva:B
18 1k77:A 260 228 0.1812 0.2000 0.2281 1.31e-04
19 3wqo:A 271 125 0.1045 0.1107 0.2400 0.003 3wqo:B
20 5hmq:D 624 130 0.0976 0.0449 0.2154 0.030 5hmq:A, 5hmq:B, 5hmq:C, 5hmq:E, 5hmq:F
21 6yx5:B 339 71 0.0732 0.0619 0.2958 0.16
22 7vpf:A 273 133 0.1010 0.1062 0.2180 0.23 7vpf:B
23 6mss:A 181 69 0.0697 0.1105 0.2899 0.36
24 1txo:B 236 22 0.0523 0.0636 0.6818 0.64 2cm1:A, 1txo:A
25 5vkt:A 353 43 0.0557 0.0453 0.3721 0.96 5vkt:B
26 5j7i:B 456 85 0.0976 0.0614 0.3294 1.8 5j7i:C, 5j7i:D
27 3zd7:A 623 128 0.1045 0.0482 0.2344 2.6 8g7t:C
28 5x7o:A 1247 123 0.1045 0.0241 0.2439 2.8 5x7o:B, 5x7p:B, 5x7p:A, 5x7q:A, 5x7q:B, 5x7r:A, 5x7r:B, 5x7s:A, 5x7s:B
29 1yqd:A 359 35 0.0488 0.0390 0.4000 4.5 1yqd:B, 1yqx:A, 1yqx:B
30 1e6y:F 247 52 0.0662 0.0769 0.3654 6.5 1e6y:C, 8gf5:E
31 2c1w:B 276 67 0.0662 0.0688 0.2836 6.5 2c1w:A, 2c1w:C
32 8ro4:A 339 22 0.0383 0.0324 0.5000 7.3 8ro4:C, 8ro4:D, 8ro4:B, 8ro4:E, 8ro4:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218