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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SLPREDTVYIGGALWGPATTWNLYAPQSTWGTDQFMYLPAFQYDLGRDAWIPVIAERYEFVDDKTLRIYIRPEARWSDGV
PITADDFVYALELTKELGIGPGGGWDTYIEYVKAVDTKVVEFKAKEENLNYFQFLSYSLGAQPMPKHVYERIRAQMNIKD
WINDKPEEQVVSGPYKLYYYDPNIVVYQRVDDWWGKDIFGLPRPKYLAHVIYKDNPSASLAFERGDIDWNGLFIPSVWEL
WEKKGLPVGTWYKKEPYFIPDGVGFVYVNNTKPGLSDPAVRKAIAYAIPYNEMLKKAYFGYGSQAHPSMVIDLFEPYKQY
IDYELAKKTFGTEDGRIPFDLDMANKILDEAGYKKGPDGVRVGPDGTKLGPYTISVPYGWTDWMMMCEMIAKNLRSIGID
VKTEFPDFSVWADRMTKGTFDLIISWSVGPSFDHPFNIYRFVLDKRLSKPVGEVTWAGDWERYDNDEVVELLDKAVSTLD
PEVRKQAYFRIQQIIYRDMPSIPAFYTAHWYEYSTKYWINWPSEDNPAWFRPSPWHADAWPTLFIISKKSDPQPVPSWLG
TVDEGGIEIPTAKIFEDLQKAT

The query sequence (length=582) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3i5o:A 582 582 1.0000 1.0000 1.0000 0.0 3i5o:B, 4jsd:A, 4jso:A, 2o7i:A
2 4pfy:A 539 533 0.2990 0.3228 0.3265 5.78e-80 4pft:A, 4pft:B, 4pfy:B
3 4pfu:B 542 548 0.2921 0.3137 0.3102 6.86e-69 5hm4:B, 4pfu:A, 4pfw:A, 4pfw:B
4 7ebi:A 537 524 0.2216 0.2402 0.2462 7.61e-33 7ebm:A, 6lzq:A, 6lzt:A, 6lzu:A, 6lzv:A, 6lzw:A
5 4gfr:A 529 532 0.2199 0.2420 0.2406 1.90e-27 8i5j:A, 8i5j:B, 8i5k:A, 1zu0:A
6 2d5w:A 602 555 0.2320 0.2243 0.2432 1.41e-16 2d5w:B
7 3tcf:A 517 513 0.2113 0.2379 0.2398 4.03e-14 3tcf:B, 3tcf:C, 3tcf:D, 3tcf:E, 3tcf:F, 3tcf:G, 3tcf:H, 3tcg:A, 3tcg:B, 3tcg:C, 3tcg:D, 3tcg:E, 3tcg:F, 3tcg:G, 3tcg:H
8 4oes:A 498 260 0.1271 0.1486 0.2846 1.52e-13
9 6ofq:A 512 458 0.1821 0.2070 0.2314 1.38e-12 6pu3:A
10 6hlx:A 491 494 0.2045 0.2424 0.2409 1.56e-12
11 8arn:A 509 476 0.1856 0.2122 0.2269 5.96e-12 8are:A, 8arn:B
12 7z8e:A 590 408 0.1649 0.1627 0.2353 4.04e-11
13 1b05:A 517 484 0.1735 0.1954 0.2087 1.23e-10 1b0h:A, 1b1h:A, 1b2h:A, 1b32:A, 1b3f:A, 1b3g:A, 1b3h:A, 1b3l:A, 1b3l:C, 1b40:A, 1b46:A, 1b4h:A, 1b4z:A, 1b51:A, 1b52:A, 1b58:A, 1b5h:A, 1b5i:A, 1b5j:A, 1b6h:A, 1b7h:A, 1b9j:A, 1jet:A, 1jeu:A, 1jev:A, 1ola:A, 1olc:A, 2olb:A, 1qka:A, 1qkb:A, 2rkm:A
14 5yh8:A 510 421 0.1684 0.1922 0.2328 1.92e-10 5yhe:A, 5yhe:B, 5yhg:A
15 6dtg:A 522 481 0.1907 0.2126 0.2308 2.19e-10 6dqq:A, 6dqr:A, 6dqt:A, 6dqu:A, 6dtf:A, 6dth:A
16 1xoc:A 504 454 0.1890 0.2183 0.2423 1.29e-09
17 2z23:A 517 486 0.1770 0.1992 0.2119 2.51e-09
18 6tfx:B 494 319 0.1306 0.1538 0.2382 2.88e-09 6tfq:A, 6tfq:B, 6tfs:A, 6tfs:B, 6tfx:A
19 3zs6:A 506 512 0.1873 0.2154 0.2129 3.85e-09
20 4qfl:A 507 248 0.1065 0.1223 0.2500 3.06e-08 4qfl:B, 4qfn:A, 4qfn:B, 4qfo:A, 4qfo:B, 4qfp:A, 4qfp:B
21 4gl8:A 500 517 0.2027 0.2360 0.2282 4.03e-08 4gl8:B
22 3e3k:B 500 436 0.1735 0.2020 0.2317 4.18e-08 7a0c:A, 7a0c:B, 4dcx:A, 4dcx:B, 4dcy:A, 4dcy:B, 3dp8:A, 3dp8:B, 3dp8:C, 3e3k:A, 3e3k:C, 4i8c:A, 4i8c:B, 4i8c:C, 4i9d:A, 4i9d:B, 5l8d:A, 5l8d:B, 3mvw:A, 3mvw:B, 3mvx:A, 3mvx:B, 3mvy:A, 3mvy:B, 3mvz:A, 3mvz:B, 3mw0:A, 3mw0:B, 5mwu:A, 5mwu:B, 3mz9:A, 3mz9:B, 3mzb:A, 3mzb:B, 2noo:A, 5on0:A, 5on0:B, 5on1:A, 5on1:B, 5on4:A, 5on4:B, 5on5:A, 5on5:B, 5on8:A, 5on8:B, 5on9:A, 5on9:B, 6r4q:A, 6r4q:B, 8spm:A, 1zlq:A, 1zlq:B
23 4oev:A 494 452 0.1856 0.2186 0.2389 4.76e-08 4oeu:A, 4oeu:B, 4oev:B
24 8upi:A 510 288 0.1151 0.1314 0.2326 1.49e-07
25 7z6f:E 581 412 0.1701 0.1704 0.2403 2.86e-07 7atr:A, 8fsq:A, 8fsr:A, 8fss:A
26 7veu:A 612 455 0.1804 0.1716 0.2308 2.86e-07 7vev:A, 7vew:A, 7vew:B
27 3o9p:A 509 479 0.1667 0.1906 0.2025 4.12e-07
28 1dpp:A 507 499 0.1701 0.1953 0.1984 9.36e-07 1dpp:C, 1dpp:E, 1dpp:G
29 7kz9:A 478 462 0.1753 0.2134 0.2208 1.21e-06 7kz9:B
30 5z99:A 485 482 0.1890 0.2268 0.2282 2.11e-06 5yyb:A, 5yyb:B
31 3ryb:A 563 509 0.2045 0.2114 0.2338 5.00e-06 3drf:A, 3drg:A, 3drh:A, 3dri:A, 3drj:A, 3drk:A, 3rya:A
32 8cko:A 492 479 0.1684 0.1992 0.2046 9.15e-06 8ckd:A, 8cke:A, 6i7w:A, 4ra1:A, 4ze9:A, 4zeb:A, 4zeb:B, 4zec:A, 4zed:A, 4zei:A, 4zek:A
33 8ay0:B 496 476 0.1787 0.2097 0.2185 9.27e-06 8ay0:A, 8ay0:C
34 8ch2:A 479 366 0.1306 0.1587 0.2077 2.74e-04 8ch1:A, 8ch3:A, 8chc:A, 8ci6:A, 8cju:A
35 5f1q:A 513 493 0.1667 0.1891 0.1968 2.85e-04 5f1q:B
36 4ofo:A 497 391 0.1478 0.1730 0.2199 3.52e-04 4ofl:A, 4ofl:B, 4ofo:B, 4ofo:C, 4ofo:D
37 7og0:B 498 120 0.0584 0.0683 0.2833 8.66e-04 7ofw:A, 7ofz:A, 7og0:A
38 5kzt:B 510 52 0.0412 0.0471 0.4615 0.002 5kzt:A
39 8j5u:A 534 463 0.1701 0.1854 0.2138 0.008 8j5q:A, 8j5s:A
40 8caw:A 491 478 0.1632 0.1935 0.1987 0.013 8cay:A, 8cb9:A, 8cdo:A
41 1uqw:A 487 283 0.1082 0.1294 0.2226 0.026 1uqw:B
42 2wop:A 554 512 0.1907 0.2004 0.2168 0.027 2wok:A
43 4faj:A 507 27 0.0292 0.0335 0.6296 0.058
44 6epz:C 673 215 0.0945 0.0817 0.2558 0.14 6epy:A, 6epy:B, 6epy:C, 6epy:D, 6epz:A, 6epz:D, 6epz:B, 6eq0:A, 6eq0:B, 6eq1:A, 6eq1:B, 6eq8:D, 6eq8:B, 6eq8:C, 6eq8:A
45 3m8u:A 508 242 0.0893 0.1024 0.2149 0.16
46 6npo:A 518 41 0.0292 0.0328 0.4146 0.44
47 8wda:A 517 217 0.0773 0.0870 0.2074 0.73 6e3d:A, 6e4d:A, 7jls:A
48 6sj2:B 503 54 0.0292 0.0338 0.3148 0.76 6sj0:A, 6sj0:B, 6sj1:A, 6sj1:B, 6sj2:A, 6sj3:A, 6sj3:B, 6sj4:A, 6sj4:B
49 3ai2:A 263 68 0.0395 0.0875 0.3382 3.5 3ai2:B, 3ai2:H, 3ai2:D, 3ai2:E, 3ai2:C, 3ai2:F, 3ai2:G, 3ai3:A, 3ai3:C, 3ai3:E, 3ai3:G
50 5uwu:C 998 72 0.0361 0.0210 0.2917 3.7 6a38:C, 6a3a:C, 6a3b:C, 6a3c:C, 6a3e:C, 6cit:C, 7cnd:C, 5dh9:C, 5dha:C, 5dhf:C, 5di9:C, 5dif:C, 8hq3:C, 8hq4:C, 8hq5:C, 8hq6:C, 8huf:C, 8hug:C, 8itv:C, 6kft:C, 6m60:C, 6m6x:C, 5uwj:C, 5uwo:C, 5uwp:C, 5uws:C, 6x2p:C, 6x2r:C, 6x2s:C, 6x2u:C, 6x2v:C, 6x2w:C, 6x2x:C, 6x2y:C, 7ypz:C
51 4eac:C 396 57 0.0292 0.0429 0.2982 4.0 4eac:A, 4eac:B, 4eac:D, 4eay:A, 4eay:B, 4eay:C, 4eay:D
52 5k2m:G 273 73 0.0361 0.0769 0.2877 5.0 5k2m:I, 5k2m:A, 5k2m:B, 5k2m:C, 5k2m:D, 5k2m:H, 5k2m:J
53 2arc:B 164 38 0.0258 0.0915 0.3947 5.2 2aac:A, 2aac:B, 2arc:A
54 4v8p:BW 110 38 0.0292 0.1545 0.4474 5.7 4v8p:CW, 4v8p:EW, 4v8p:GW
55 4ofm:B 206 48 0.0275 0.0777 0.3333 6.0 4ofm:A, 4ofm:C, 4ofm:D, 4ofn:A, 4ofn:B
56 3kf9:A 149 49 0.0258 0.1007 0.3061 8.9 3kf9:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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