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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SLLQAGRFVVMLQGRHAGKKAVVLAAYGTEDRKFPYAIVMGIEKYPKKVTKDMPTEVLVKKTQVKLFVKAVNFNHVMLTR
HNVKEDFFKKISVEKVVAALKDAPAKKALLTEYAAVLRQKYLNNKMAWFFKPLQF

The query sequence (length=135) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5xy3:Z 135 135 1.0000 1.0000 1.0000 3.48e-96
2 4v8p:AN 143 141 0.4222 0.3986 0.4043 9.32e-27 4v8p:DN, 4v8p:FN, 4v8p:HN
3 6zj3:Ln 133 138 0.4000 0.4060 0.3913 1.13e-26
4 9bh5:CZ 135 136 0.3778 0.3778 0.3750 1.04e-25 9cai:CZ
5 8esq:Z 134 136 0.3630 0.3657 0.3603 1.72e-25 8esr:Z, 8etc:Z, 8eug:Z, 8eui:Z
6 8azw:M 134 136 0.3778 0.3806 0.3750 3.72e-25 8b2l:M3, 7qiw:b, 7qiz:b
7 8ip8:CA 136 136 0.3852 0.3824 0.3824 2.34e-24 8ipa:CA, 8ipb:CA, 8jiv:CZ, 4v3p:La, 4v7e:CZ
8 7r81:b1 135 137 0.3630 0.3630 0.3577 5.09e-24
9 4d5y:Z 136 139 0.3556 0.3529 0.3453 7.64e-24 7a01:22, 8a3d:T, 5aj0:AZ, 8b5l:Z, 8b6c:Z, 9bdl:AL27, 9bdn:AL27, 9bdp:AL27, 7bhp:LZ, 8bhf:M1, 8bpo:Y2, 8btk:BZ, 7cpu:LZ, 7cpv:LZ, 4d67:Z, 6d90:Z, 6d9j:Z, 9f1b:BZ, 9f1c:BZ, 9f1d:BZ, 7f5s:LZ, 8fky:LJ, 8fkz:LJ, 8fl2:LJ, 8fl3:LJ, 8fl4:LJ, 8fl6:LJ, 8fl7:LJ, 8fl9:LJ, 8fla:LJ, 8flb:LJ, 8flc:LJ, 8fld:LJ, 8fle:LJ, 8flf:LJ, 6frk:Z, 6ftg:Z, 6fti:Z, 6ftj:Z, 8g5y:LZ, 8g5z:LZ, 8g60:LZ, 8g61:LZ, 8g6j:LZ, 8glp:LZ, 6gz3:AZ, 6gz4:AZ, 6gz5:AZ, 6hcf:Z3, 6hcj:Z3, 6hcm:Z3, 6hcq:Z3, 8idt:i, 8idy:i, 8ie3:i, 8ifd:2T, 8ife:2T, 8ine:i, 8inf:i, 8ink:i, 6ip5:2T, 6ip6:2T, 6ip8:2T, 8ipd:i, 8ipx:i, 8ipy:i, 8ir1:i, 8ir3:i, 3j7o:Z, 3j7p:Z, 3j7q:Z, 3j7r:Z, 3j92:Z, 3jag:Z, 3jah:Z, 3jai:Z, 3jaj:Z, 3jan:Z, 8jdj:e, 8jdk:e, 8jdl:e, 8jdm:e, 8k2c:LZ, 5lks:LZ, 6lqm:i, 6lsr:i, 6lss:i, 7ls1:T2, 7ls2:T2, 6lu8:i, 5lzs:Z, 5lzt:Z, 5lzu:Z, 5lzv:Z, 5lzw:Z, 5lzx:Z, 5lzy:Z, 5lzz:Z, 7mdz:Z, 6mtb:Z, 6mtc:Z, 6mtd:Z, 6mte:Z, 7nfx:Z, 7nwg:Z3, 7nwh:Z, 7nwi:Z, 7o7y:BZ, 7o7z:BZ, 7o80:BZ, 7o81:BZ, 7obr:Z, 8ohd:LZ, 8oj0:LZ, 8oj5:LZ, 8oj8:LZ, 6ole:a, 6olf:a, 6olg:AZ, 6oli:a, 6olz:AZ, 6om0:a, 6om7:a, 7ow7:T, 7oya:Z1, 7oyb:Z1, 7oyc:Z1, 7oyd:Z, 8p2k:BZ, 6p5i:AZ, 6p5j:AZ, 6p5k:AZ, 6p5n:AZ, 8q7z:BZ, 8q87:BZ, 8qfd:Z, 7qgg:a, 8qoi:LZ, 7qvp:LZ, 7qvp:MZ, 7qwq:Z, 7qwr:Z, 7qws:Z, 6qzp:LZ, 6r5q:Z, 6r6g:Z, 6r6p:Z, 6r7q:Z, 8rjb:Z, 8rjc:Z, 8rjd:Z, 8scb:Z, 6sgc:Z2, 6swa:X, 5t2c:T, 6t59:Z3, 7tm3:Z, 7toq:AL27, 7tor:AL27, 7tut:Z, 7ucj:Z, 7uck:Z, 4ug0:LZ, 4ujc:BZ, 4ujd:AZ, 4uje:CZ, 4v6x:CZ, 6w6l:a, 6xa1:LZ, 7xnx:LZ, 7xny:LZ, 8xsx:LZ, 8xsy:LZ, 8xsz:LZ, 6y0g:LZ, 8y0w:LZ, 8y0x:LZ, 6y2l:LZ, 6y57:LZ, 6y6x:LZ, 8yoo:LZ, 8yop:LZ, 6z6l:LZ, 6z6m:LZ, 6z6n:LZ, 7zjw:Lc, 7zjx:Lc, 6zm7:LZ, 6zme:LZ, 6zmi:LZ, 6zmo:LZ, 6zvk:22
10 5xxb:Y 144 110 0.3630 0.3403 0.4455 1.33e-23
11 3j79:1 140 88 0.2963 0.2857 0.4545 6.63e-23 3jbn:A1, 3jbo:A1, 3jbp:A1, 8tpu:A1, 5umd:1
12 8i9x:LZ 135 137 0.3407 0.3407 0.3358 2.13e-22 8i9y:LZ, 8i9z:LZ, 8ia0:LZ, 7olc:LZ, 7old:LZ, 8oo0:LZ, 8pv1:LZ, 8pv2:LZ, 8pv3:LZ, 8pv4:LZ, 8pv5:LZ, 8pv6:LZ, 8pv7:LZ, 8pv8:LZ, 8pvk:LZ, 8pvl:LZ, 7z3n:LZ, 7z3o:LZ
13 8aaf:M 135 137 0.3556 0.3556 0.3504 7.40e-22 8agt:M, 8agu:M, 8agv:M, 8agw:M, 8agx:M, 8agz:M, 5apn:Z, 5apo:Z, 7azy:O, 7b7d:LV, 8bip:LZ, 8bjq:LZ, 8bn3:N7, 8bqd:AN, 8bqx:AN, 7bt6:Z, 7btb:Z, 6cb1:Z, 8ccs:L, 8cdl:L, 8cdr:L, 8ceh:L, 8cf5:L, 8cg8:L, 8cgn:L, 8civ:L, 8cku:L, 8cmj:L, 5dat:N7, 5dat:n7, 5dc3:N7, 5dc3:n7, 5dge:N7, 5dge:n7, 5dgf:N7, 5dgf:n7, 5dgv:N7, 5dgv:n7, 6elz:Z, 8eub:AZ, 8evp:AZ, 8evq:AZ, 8evr:AZ, 8evs:AZ, 8evt:AZ, 8ewb:AZ, 8ewc:AZ, 5fci:N7, 5fci:n7, 5fcj:N7, 5fcj:n7, 6ft6:Z, 5gak:b, 6gq1:Z, 6gqb:Z, 6gqv:Z, 5h4p:Z, 6hd7:b, 8hfr:Zq, 6hhq:AA, 6hhq:DB, 5i4l:N7, 5i4l:n7, 6i7o:AN, 6i7o:XN, 5it7:ZZ, 3j6x:67, 3j6y:67, 3j77:77, 3j78:77, 3jct:Z, 5jcs:Z, 5juo:EA, 5jup:EA, 5jus:EA, 5jut:EA, 5juu:EA, 8k2d:LZ, 8k82:LZ, 5lyb:N7, 5lyb:n7, 5m1j:Z5, 6m62:Z, 5mc6:AN, 5mei:AA, 5mei:DB, 7mpi:AZ, 7mpj:AZ, 6n8j:Z, 6n8k:Z, 6n8l:Z, 6n8m:m, 6n8n:m, 6n8o:m, 7n8b:AZ, 7nac:Z, 7nad:Z, 5ndg:N7, 5ndg:n7, 5ndv:N7, 5ndv:n7, 5ndw:N7, 5ndw:n7, 7nrc:Lb, 7nrd:Lb, 5obm:N7, 5obm:n7, 7of1:Z, 7oh3:Z, 7ohq:Z, 7ohr:Z, 7ohv:Z, 6oig:Z, 5on6:AA, 5on6:DB, 7osa:eL27, 7osm:eL27, 8p8m:QZ, 8p8n:QZ, 8p8u:QZ, 8pfr:QZ, 6q8y:AN, 6qik:Y, 6qt0:Y, 6qtz:Y, 7r72:Z, 7r7a:Z, 6r84:b, 6r86:b, 6r87:b, 6ri5:Y, 7rr5:LZ, 6rzz:Y, 6s05:Y, 6s47:Ab, 6snt:aq, 6sv4:AN, 6sv4:XN, 6sv4:zN, 6t4q:LZ, 5t62:m, 5t6r:m, 6t7i:LZ, 6t7t:LZ, 6t83:Zy, 6t83:K, 5tbw:AA, 5tbw:DB, 6tb3:AN, 5tga:N7, 5tga:n7, 5tgm:N7, 5tgm:n7, 6tnu:AN, 7too:AL27, 7top:AL27, 7u0h:Z, 4u3m:N7, 4u3m:n7, 4u3n:N7, 4u3n:n7, 4u3u:N7, 4u3u:n7, 4u4n:N7, 4u4n:n7, 4u4o:N7, 4u4o:n7, 4u4q:N7, 4u4q:n7, 4u4r:N7, 4u4r:n7, 4u4u:N7, 4u4u:n7, 4u4y:N7, 4u4y:n7, 4u4z:N7, 4u4z:n7, 4u50:N7, 4u50:n7, 4u51:N7, 4u51:n7, 4u52:N7, 4u52:n7, 4u53:N7, 4u53:n7, 4u55:N7, 4u55:n7, 4u56:N7, 4u56:n7, 4u6f:N7, 4u6f:n7, 7ug6:Z, 7uoo:Z, 7uqb:Z, 7uqz:Z, 6uz7:AZ, 7v08:Z, 4v6i:Ba, 4v7f:Y, 4v88:BZ, 4v88:DZ, 4v8t:Z, 4v8y:BZ, 4v8z:BZ, 8v87:Z, 4v91:Z, 6woo:Z, 6xiq:Z, 6xir:Z, 8y0u:LZ, 6ylg:Z, 6ylh:Z, 6ylx:Z, 6yly:Z, 7z34:Z, 6z6j:LZ, 6z6k:LZ, 7zpq:BY, 7zrs:BY, 7zs5:Ba, 7zuw:BY, 7zux:EY, 7zw0:Lc
14 8fru:Z 134 132 0.3185 0.3209 0.3258 2.08e-20 8brm:La, 8bsi:La, 8bsj:La, 8btd:La, 8btr:La, 7pwg:Z, 7pwo:Z2
15 4v6w:CZ 134 136 0.3704 0.3731 0.3676 3.72e-20 6xu6:CZ, 6xu7:CZ, 6xu8:CZ
16 8c3a:AA 135 137 0.3778 0.3778 0.3723 5.39e-20 8c3a:BU, 8cq7:AA, 8cq7:BU, 8cqw:AA, 8cqw:BU, 8cre:AA, 8cre:BU, 8oeq:AA, 8oeq:BU, 7pzy:AA, 7q08:AA, 7q0f:AA, 7q0p:AA, 7q0r:AA, 8q5i:AA
17 8ova:Ba 132 137 0.3481 0.3561 0.3431 9.77e-20 8ove:Ba, 4v8m:Ba
18 8rxh:LY 133 136 0.3259 0.3308 0.3235 1.90e-18 8a3w:Y, 8a98:Y, 6az3:Y, 3jcs:Y, 8ovj:Y, 8rxx:LY, 5t2a:Y
19 8br8:La 119 132 0.2889 0.3277 0.2955 8.06e-15
20 5t5h:a 105 92 0.2148 0.2762 0.3152 2.16e-12
21 6zu5:LZ0 127 81 0.2519 0.2677 0.4198 1.86e-09
22 8p5d:LZ0 118 134 0.2444 0.2797 0.2463 3.90e-06 8p60:LZ0, 8p60:KZ0, 7qca:LZ0
23 6rm3:LZ0 125 130 0.2667 0.2880 0.2769 0.001
24 5fm6:A 426 121 0.2444 0.0775 0.2727 0.10 5fm7:A, 4ww4:A
25 8av6:C 459 56 0.1556 0.0458 0.3750 0.11 8av6:A, 8av6:B, 6fhs:A, 6fhs:B, 6fhs:C, 6fml:A, 6fml:B, 6fml:C, 8oo7:A, 8oo7:B, 8oo7:C, 8ooc:A, 8ooc:B, 8ooc:C, 8oop:A, 8oop:B, 8oop:C, 8oor:A, 8oor:B, 8oor:C, 4wvy:A
26 7qep:N7 118 127 0.2370 0.2712 0.2520 0.16
27 5xy3:E 135 26 0.0889 0.0889 0.4615 0.62
28 8hku:L141 86 22 0.0741 0.1163 0.4545 1.2 8hku:L142, 8hkv:L141, 8hkv:L142, 8hky:L141, 8hky:L142, 8hkz:L141, 8hkz:L142, 8hl1:L141, 8hl1:L142, 8hl2:L141, 8hl2:L142, 8hl3:L141, 8hl3:L142, 8hl4:L141, 8hl4:L142, 8hl5:L141, 8hl5:L142
29 6qi8:A 317 93 0.2000 0.0852 0.2903 1.7 7aho:B, 6qi8:B, 6qi9:A, 6qi9:B
30 2bib:A 540 53 0.1111 0.0278 0.2830 1.8 1wra:A, 1wra:B
31 9ema:A 326 56 0.1407 0.0583 0.3393 2.6 7aho:A, 7aho:C, 2c9o:C, 9ema:B, 9ema:C, 9emc:A, 9emc:B, 9emc:C, 6fo1:A, 6fo1:B, 6fo1:C, 6k0r:A, 6k0r:B, 6k0r:C, 6k0r:G, 6k0r:H, 6k0r:I, 7p6x:A, 7p6x:B, 7p6x:C, 6qi8:C, 6qi9:C, 2xsz:A, 2xsz:B, 2xsz:C
32 7ole:C 427 56 0.1407 0.0445 0.3393 2.7 7ole:E
33 8ets:V 443 126 0.2370 0.0722 0.2540 2.7 8ets:X, 8ets:T, 8etu:V, 8etu:X, 8etu:T, 8etw:V, 8etw:X, 8etw:T, 8eu9:V, 8eu9:X, 8eu9:T, 8euf:V, 8euf:X, 8euf:T, 6gej:T, 6gej:V, 6gej:X, 6gen:T, 6gen:V, 6gen:X
34 3cf4:A 766 46 0.1185 0.0209 0.3478 2.8
35 8q87:BE 225 27 0.0815 0.0489 0.4074 3.1 8q7z:BE
36 7zi4:C 447 56 0.1407 0.0425 0.3393 3.3 9c57:E, 9c57:C, 9c57:A, 9c62:C, 9c62:E, 9c62:A, 6hts:A, 6hts:C, 6hts:E, 5oaf:A, 5oaf:C, 5oaf:E, 8x15:M, 8x15:O, 8x15:Q, 8x19:M, 8x19:O, 8x19:Q, 8x1c:M, 8x1c:O, 8x1c:Q, 8xvg:A, 8xvg:C, 8xvg:E, 8xvt:A, 8xvt:C, 8xvt:E, 7zi4:A, 7zi4:E
37 2c9o:A 398 56 0.1407 0.0477 0.3393 3.3 2c9o:B
38 4v4n:A5 81 46 0.1037 0.1728 0.3043 4.7 4v4n:AK, 4v6u:B5, 4v6u:BK
39 3rpc:A 262 69 0.1556 0.0802 0.3043 5.0 3rpc:B, 3rpc:C, 3rpc:D
40 6skf:BM 81 21 0.0741 0.1235 0.4762 5.3 6skf:BN, 6skg:BM, 6skg:BN, 6th6:BM, 6th6:BN
41 6pvk:U 90 30 0.0741 0.1111 0.3333 6.7
42 5min:B 453 44 0.0741 0.0221 0.2273 6.9 1c9u:A, 1c9u:B, 1cq1:A, 1cq1:B, 1cru:A, 1cru:B, 5min:A, 1qbi:A, 1qbi:B, 8re0:A, 8re0:B, 8rfk:A, 8rfk:B, 8rg1:A, 8rg1:B
43 4v6w:CE 228 22 0.0741 0.0439 0.4545 7.1 6xu6:CE, 6xu7:CE, 6xu8:CE
44 3j3v:U 103 30 0.0741 0.0971 0.3333 7.5 7aqc:U, 7aqd:U, 7as8:Y, 7as9:Y, 8buu:U, 6ha1:U, 6ha8:U, 6htq:U, 3j3w:U, 3j9w:BX, 5njt:n, 7o5b:t, 7ope:Y, 6ppf:U, 6ppk:U, 8qcq:U, 7qgu:U, 7qh4:U, 8qpp:t, 7qv1:U, 7qv2:U, 7qv3:U, 8r55:t, 8s1p:U, 8s1u:U, 7s9u:U, 7sae:U, 6tnn:n, 6tpq:n
45 7oyc:E1 214 24 0.0741 0.0467 0.4167 9.6

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218