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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SLKIAKVEALSVAMGPTSAFVRITAEDGTVGWGEASPMLGGIASLGVVARDIAPFLEGQEVLDHAVLLDRMMHRLVKLGP
EGIATAALAACDIALWDLKGKLLGQPIYKLLGGAWRTRLPCYSSIGGNAARSVDEVVREVARRVEAEQPAAVKIRWDGDR
TRCDVDIPGDIAKARAVRELLGPDAVIGFDANNGYSVGGAIRVGRALEDLGYSWFEEPVQHYHVGAMGEVAQRLDITVSA
GEQTYTLQALKDLILSGVRMVQPDIVKMGGITGMMQCAALAHAHGVEFVPHQTQPGVGHFANIHVLSTLMHMTKPVELAD
RWDRGRPVFRNPAEPVDGHFALGDAPGLGIVVDEDELASRATEITVG

The query sequence (length=367) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3n4e:A 368 367 1.0000 0.9973 1.0000 0.0 3n4e:B
2 3u4f:A 371 373 0.3215 0.3181 0.3164 1.08e-42 3u4f:B, 3u4f:C, 3u4f:D
3 4hpn:A 378 350 0.3106 0.3016 0.3257 1.98e-42 4ggb:A
4 3tcs:B 367 361 0.3106 0.3106 0.3158 9.75e-42 3tcs:A
5 3t8q:B 369 373 0.3079 0.3062 0.3029 1.51e-41 3t8q:A
6 5olc:C 351 360 0.3025 0.3162 0.3083 3.27e-41 5olc:D, 5olc:F, 5olc:G, 5olc:H
7 3bjs:B 376 373 0.3297 0.3218 0.3244 2.84e-40 3bjs:A
8 4h19:A 372 336 0.2916 0.2876 0.3185 8.75e-38 4h19:B, 4h19:C, 4h19:D, 4h19:F, 4h19:E, 4h19:G, 4h19:H, 4h19:I, 4h19:K, 4h19:L, 4h19:M, 4h19:N, 4h19:P, 4h19:J, 4h19:O
9 3sjn:A 373 379 0.2861 0.2815 0.2770 5.73e-36 3sjn:B
10 2pp1:A 395 346 0.2807 0.2608 0.2977 2.47e-35 2pp1:B, 2pp1:C, 2pp1:D, 2pp1:E, 2pp1:F, 2pp3:A, 2pp3:B, 2pp3:C
11 3sqs:A 386 362 0.2916 0.2772 0.2956 8.58e-35
12 3stp:A 390 347 0.2861 0.2692 0.3026 3.13e-33
13 2qq6:B 396 381 0.3106 0.2879 0.2992 8.00e-33 2qq6:A
14 3rcy:F 397 351 0.2589 0.2393 0.2707 4.07e-32 3rcy:A, 3rcy:C, 3rcy:B, 3rcy:D, 3rcy:E, 3rcy:G, 3rcy:H
15 2o56:A 392 393 0.2779 0.2602 0.2595 2.24e-30 2o56:B, 2o56:C, 2o56:D, 2o56:E, 2o56:F, 2o56:G, 2o56:H
16 5xd8:B 367 275 0.2371 0.2371 0.3164 7.00e-30 5xd7:A, 5xd8:A, 5xd9:A
17 2ox4:C 397 387 0.2834 0.2620 0.2687 5.24e-29 2ox4:A, 2ox4:B, 2ox4:D, 2ox4:E, 2ox4:F, 2ox4:G, 2ox4:H
18 3cb3:A 373 350 0.2752 0.2708 0.2886 1.01e-28 3cb3:B, 3cb3:C, 3cb3:D, 2og9:A, 2og9:B
19 3d46:A 405 347 0.2698 0.2444 0.2853 4.58e-28 3box:A, 3box:B, 3cxo:A, 3cxo:B, 3d46:B, 3d46:C, 3d46:D, 3d46:E, 3d46:F, 3d46:G, 3d46:H, 3d47:A, 3d47:B, 3d47:C, 3d47:D, 3d47:E, 3d47:F, 3d47:G, 3d47:H, 2gsh:A, 2gsh:B
20 3ck5:A 357 343 0.2834 0.2913 0.3032 2.38e-27 3ck5:B, 3ck5:C, 3ck5:D
21 3mqt:E 378 371 0.2670 0.2593 0.2642 3.04e-27 3mqt:A, 3mqt:D, 3mqt:F, 3mqt:G, 3mqt:H, 3mqt:K, 3mqt:L, 3mqt:U, 3mqt:V, 3mqt:W, 3mqt:X
22 4h1z:B 388 279 0.2371 0.2242 0.3118 8.48e-27 4h1z:A, 4h1z:C, 4h1z:D, 4h1z:E, 4h1z:F, 4h1z:G, 4h1z:H
23 3ekg:A 395 346 0.2534 0.2354 0.2688 4.25e-26 3ekg:B
24 3ugv:F 364 347 0.2670 0.2692 0.2824 7.66e-26 3ugv:A, 3ugv:B, 3ugv:C, 3ugv:D, 3ugv:E, 3ugv:G, 3ugv:H
25 2qgy:A 376 341 0.2125 0.2074 0.2287 4.73e-25 2qgy:B
26 3tte:A 361 294 0.2262 0.2299 0.2823 1.03e-24 3toy:A, 3toy:B, 3toy:C, 3toy:D, 3tte:B
27 4hcd:A 384 362 0.2807 0.2682 0.2845 1.44e-24 4hch:A, 4hch:B, 4hcl:A, 4hcl:B, 4mmw:A, 4mmw:B, 1rvk:A
28 4h83:F 368 325 0.2616 0.2609 0.2954 1.84e-24 4h83:A, 3no1:A, 3no1:B, 3no1:C, 3no1:D, 3no1:E, 3no1:F
29 3rra:B 379 366 0.2861 0.2770 0.2869 4.62e-24 3rra:A
30 3ozm:A 386 357 0.2916 0.2772 0.2997 5.00e-24 3op2:A, 3op2:B, 3ozm:B, 3ozm:C, 3ozm:D, 3ozm:E, 3ozm:F, 3ozm:G, 3ozm:H, 3ozy:A, 3ozy:B
31 3fcp:A 356 355 0.2888 0.2978 0.2986 3.90e-23 3fcp:B, 3fcp:C, 3fcp:D, 3fcp:E, 3fcp:F, 3fcp:G, 3fcp:H
32 4e6m:A 401 395 0.2589 0.2369 0.2405 5.75e-23 4e6m:B, 4e6m:C, 4e6m:D, 4e6m:E, 4e6m:F, 4e6m:G, 4e6m:H, 2gl5:A, 2gl5:B
33 3fxg:A 407 293 0.2234 0.2015 0.2799 8.29e-23 3fxg:B, 3fxg:C, 3fxg:D, 3fxg:E, 3fxg:F, 3fxg:G, 3fxg:H
34 3i6t:B 364 368 0.2725 0.2747 0.2717 1.49e-22 3i6t:A, 3i6t:C, 3i6t:D
35 1jpm:A 359 359 0.2643 0.2702 0.2702 1.96e-22 1jpm:B, 1jpm:C, 1jpm:D, 1tkk:A, 1tkk:B, 1tkk:C, 1tkk:D, 1tkk:E, 1tkk:F, 1tkk:G, 1tkk:H
36 2p88:A 369 353 0.2398 0.2385 0.2493 4.55e-22 2p88:B, 2p88:C, 2p88:D, 2p88:E, 2p88:F, 2p88:G, 2p88:H, 2p8b:A, 2p8c:A
37 4dn1:A 389 345 0.2698 0.2545 0.2870 6.59e-22 4dn1:B
38 7mqx:E 358 294 0.2234 0.2291 0.2789 3.01e-21 1dtn:A, 4fp1:A, 4fp1:B, 4hnc:A, 4hnc:B, 4m6u:A, 4m6u:B, 1mdl:A, 1mdr:A, 1mns:A, 2mnr:A, 7mqx:A, 7mqx:B, 7mqx:C, 7mqx:D, 7mqx:F, 7mqx:G, 7mqx:H, 1mra:A, 3uxk:A, 3uxk:B, 3uxk:C, 3uxk:D, 3uxl:A, 3uxl:B, 3uxl:C, 3uxl:D, 6vim:A, 6vim:B, 6vim:C, 6vim:D, 6vim:E, 6vim:F, 6vim:G, 6vim:H, 4x2p:A
39 4ihc:B 395 378 0.2888 0.2684 0.2804 5.14e-20 4ihc:C, 4ihc:D, 4ihc:E, 4ihc:F, 4ihc:H
40 3twb:C 417 404 0.3052 0.2686 0.2772 6.82e-20 4ihc:A, 4ihc:G, 3twa:A, 3twa:B, 3twa:C, 3twa:D, 3twa:E, 3twb:A, 3twb:B, 3twb:D, 3twb:E
41 3jva:B 354 296 0.2180 0.2260 0.2703 1.13e-19 3jva:A, 3jva:C, 3jva:D, 3jva:E, 3jva:F, 3jva:G, 3jva:H, 3jw7:A, 3jw7:B, 3jw7:C, 3jw7:D, 3jw7:E, 3jw7:F, 3jw7:G, 3jw7:H, 3jzu:A, 3jzu:B, 3jzu:C, 3jzu:D, 3jzu:E, 3jzu:F, 3jzu:G, 3jzu:H, 3k1g:A, 3k1g:B, 3k1g:C, 3k1g:D, 3k1g:E, 3k1g:F, 3k1g:G, 3k1g:H, 3kum:A, 3kum:B, 3kum:C, 3kum:D, 3kum:E, 3kum:F, 3kum:G, 3kum:H
42 3gy1:B 388 349 0.2343 0.2216 0.2464 1.31e-19 3gy1:A, 3s47:A, 3s47:B
43 4kws:A 397 386 0.2779 0.2569 0.2642 1.43e-19 4k2s:A, 4k2s:B, 4k2s:C, 4k2s:D, 4k2s:E, 4k2s:F, 4k2s:G, 4k2s:H, 4kpl:A, 4kpl:B, 4kpl:C, 4kpl:D, 4kpl:E, 4kpl:F, 4kpl:G, 4kpl:H, 4kt2:A, 4kt2:B, 4kt2:C, 4kt2:D, 4kt2:E, 4kt2:F, 4kt2:G, 4kt2:H, 4kws:B, 4kws:C, 4kws:D, 4kws:E, 4kws:F, 4kws:G, 4kws:H, 3ow1:A, 3ow1:B, 3ow1:C, 3ow1:D, 3ow1:E, 3ow1:F, 3ow1:G, 3ow1:H, 3p93:A, 3p93:B, 3p93:C, 3p93:D, 3p93:E, 3p93:F, 3p93:G, 3p93:H, 3pk7:A, 3pk7:B, 3pk7:C, 3pk7:D, 3pk7:E, 3pk7:F, 3pk7:G, 3pk7:H, 3qke:A, 3qke:B, 3qke:C, 3qke:D, 3qke:E, 3qke:F, 3qke:G, 3qke:H, 3rgt:A, 3rgt:B, 3rgt:C, 3rgt:D
44 3v3w:A 397 388 0.2670 0.2469 0.2526 3.49e-19 3v4b:A
45 4gme:A 403 385 0.2779 0.2531 0.2649 5.36e-19 4gme:C, 3vcn:A, 3vcn:C
46 3nzg:D 380 370 0.2752 0.2658 0.2730 5.46e-19 3nzg:A, 3nzg:B, 3nzg:C
47 3i6e:A 356 353 0.2561 0.2640 0.2663 3.24e-18 3i6e:B, 3i6e:C, 3i6e:D, 3i6e:E, 3i6e:F, 3i6e:G, 3i6e:H
48 4e4f:B 381 381 0.2561 0.2467 0.2467 3.76e-18 4e4f:C, 4il2:A, 4il2:C, 4il2:D
49 4fi4:A 407 389 0.2752 0.2482 0.2596 1.87e-17 4fi4:B, 4fi4:C
50 4e5t:A 392 384 0.2589 0.2423 0.2474 1.90e-17 4e5t:B, 4e5t:C, 4e5t:D, 4e5t:E, 4e5t:F, 4e5t:G, 4e5t:H
51 1nu5:A 369 318 0.2343 0.2331 0.2704 2.42e-17
52 3thu:A 405 396 0.2725 0.2469 0.2525 3.69e-17 3thu:B, 3thu:C
53 3sn0:A 401 380 0.2534 0.2319 0.2447 5.44e-17 3go2:A, 3sn1:A, 3sn4:A
54 4il2:B 404 401 0.2670 0.2426 0.2444 6.42e-17 4e4f:A, 4e4f:D
55 3tji:A 399 354 0.2398 0.2206 0.2486 2.17e-16 3tji:B, 3tji:C, 3tji:D
56 4gir:B 411 353 0.2044 0.1825 0.2125 2.87e-15 4ggh:A, 4ggh:B, 4ggh:C, 4ggh:D, 4gir:A, 4gir:C, 4gir:D, 4gis:A, 4gis:B
57 3r25:B 399 361 0.2071 0.1905 0.2105 3.72e-15 3r25:A, 3r25:C, 3r25:D, 3r25:E, 3r25:F, 3r25:G, 3r25:H, 3sbf:A, 3sbf:B, 3sbf:C, 3sbf:D
58 2chr:A 370 314 0.2153 0.2135 0.2516 1.01e-14
59 1f9c:A 360 360 0.2534 0.2583 0.2583 2.67e-14 1f9c:B, 1muc:A, 1muc:B, 2muc:A, 2muc:B, 3muc:A, 3muc:B
60 3dgb:A 371 361 0.2480 0.2453 0.2521 2.69e-14 3ct2:A, 3ct2:B, 3fj4:A, 3fj4:B
61 3dg6:A 366 376 0.2698 0.2705 0.2633 5.68e-14 3dg3:A, 3dg7:A, 3dg7:B, 3dg7:C, 3dg7:D
62 3t6c:A 415 409 0.2943 0.2602 0.2641 1.39e-13 3t6c:B
63 1yey:C 435 239 0.1717 0.1448 0.2636 1.72e-13 2hne:A, 2hne:B, 2hne:C, 2hne:D, 2hxt:A, 2hxu:A, 1yey:A, 1yey:B, 1yey:D
64 2gge:D 376 358 0.2234 0.2181 0.2291 2.11e-13 2gge:A, 2gge:B, 2gge:C, 2gge:E, 2gge:F, 2gge:G, 2gge:H
65 2ggh:C 370 284 0.2153 0.2135 0.2782 2.33e-13 2ggh:A, 2ggh:B, 2ggh:D, 1xpy:A, 1xpy:B, 1xpy:C, 1xpy:D, 1xs2:A, 1xs2:B, 1xs2:C, 1xs2:D
66 3q45:A 368 287 0.1989 0.1984 0.2544 2.59e-13 3q45:B, 3q45:C, 3q45:D, 3q45:E, 3q45:F, 3q45:G, 3q45:H, 3q45:I, 3q4d:A, 3q4d:B, 3q4d:C, 3q4d:D, 3q4d:E, 3q4d:F, 3q4d:G, 3q4d:H, 3q4d:I
67 4mgg:A 369 351 0.2480 0.2466 0.2593 3.13e-13 4mgg:B, 4mgg:C, 4mgg:D, 4mgg:E, 4mgg:F, 4mgg:G, 4mgg:H
68 2rdx:A 369 212 0.1853 0.1843 0.3208 3.73e-13 2rdx:B, 2rdx:C, 2rdx:D, 2rdx:E, 2rdx:F, 2rdx:G, 2rdx:H
69 4hnl:A 401 365 0.2207 0.2020 0.2219 5.47e-13
70 3r11:B 364 274 0.1826 0.1841 0.2445 1.60e-12 3r0u:A, 3r10:A, 3r11:A, 3r1z:A, 3r1z:B
71 3my9:A 357 373 0.2425 0.2493 0.2386 6.16e-12
72 4a6g:A 368 195 0.1444 0.1440 0.2718 1.11e-11 4a6g:B, 4a6g:C, 4a6g:D, 5fjo:A, 5fjo:B, 5fjp:A, 5fjp:B, 5fjp:C, 5fjp:D, 5fjr:A, 5fjr:B, 5fjr:C, 5fjr:D, 5fjt:A, 5fjt:B, 5fjt:C, 5fjt:D, 5fju:A, 5fju:B, 5fju:C, 5fju:D, 7s8w:A, 7s8w:B, 7s8w:C, 7s8w:D, 1sja:A, 1sja:B, 1sja:C, 1sja:D, 1sjb:A, 1sjb:B, 1sjb:C, 1sjb:D, 1sjc:A, 1sjc:B, 1sjc:C, 1sjc:D, 1sjd:A, 1sjd:B, 1sjd:C, 1sjd:D
73 4izg:A 369 354 0.2561 0.2547 0.2655 3.37e-11 4e8g:A, 4e8g:B, 4izg:B, 4j1o:A, 4j1o:B
74 2pmq:B 374 367 0.2643 0.2594 0.2643 3.37e-11 4h2h:A, 4h2h:B, 4h2h:C, 4h2h:D, 4h2h:E, 4h2h:F, 4h2h:G, 4h2h:H, 2pmq:A
75 3i4k:A 370 360 0.2480 0.2459 0.2528 1.09e-10 3i4k:B, 3i4k:C, 3i4k:D, 3i4k:E, 3i4k:F, 3i4k:G, 3i4k:H
76 3ijq:A 337 363 0.2725 0.2967 0.2755 2.01e-10 3iji:A, 3iji:B, 3ijl:A, 3ijl:B, 3ijq:B
77 4kem:A 390 322 0.2125 0.2000 0.2422 2.27e-10 4kem:B
78 2qjj:A 402 394 0.2643 0.2413 0.2462 2.69e-10 4k1w:A, 4k1w:B, 4k1w:C, 4k1w:D, 4k8g:A, 2qjj:B, 2qjj:C, 2qjj:D, 2qjm:A, 2qjm:B, 2qjm:C, 2qjm:D, 2qjn:A, 2qjn:B, 2qjn:C, 2qjn:D
79 3n4f:A 390 289 0.2125 0.2000 0.2699 3.47e-10 3n4f:B, 3n4f:C, 3n4f:D, 3ops:A, 3ops:B, 3ops:C, 3ops:D, 3p3b:A, 3p3b:B, 3qpe:A, 3qpe:B, 3qpe:C, 3qpe:D, 3v5c:A, 3v5c:B, 3v5c:C, 3v5c:D, 3v5f:A, 3vcc:A, 3vcc:B
80 2ps2:A 361 223 0.2071 0.2105 0.3408 8.72e-10 2ps2:B, 2ps2:C, 2ps2:D
81 3fv9:C 374 368 0.2807 0.2754 0.2799 2.81e-09 3fv9:A, 3fv9:E, 3fv9:F, 3fv9:B
82 4ip4:A 421 249 0.1853 0.1615 0.2731 3.00e-09 4ip4:B, 4ip5:A, 4ip5:B
83 3fvd:B 367 385 0.2589 0.2589 0.2468 3.09e-09 3fvd:A
84 4a35:A 441 290 0.1662 0.1383 0.2103 8.57e-09
85 3rit:A 354 264 0.1689 0.1751 0.2348 4.35e-08 3rit:B, 3rit:C, 3rit:D, 3rit:E, 3ro6:B, 3ro6:A, 3ro6:C, 3ro6:D, 3ro6:E, 3ro6:F
86 3vc6:A 420 284 0.2044 0.1786 0.2641 6.01e-08
87 2dw6:A 388 288 0.1798 0.1701 0.2292 5.12e-07 2dw6:B, 2dw6:C, 2dw6:D, 2dw7:A, 2dw7:B, 2dw7:C, 2dw7:D, 2dw7:E, 2dw7:F, 2dw7:G, 2dw7:H, 2dw7:I, 2dw7:J, 2dw7:K, 2dw7:L, 2dw7:M, 2dw7:N, 2dw7:O, 2dw7:P, 1tzz:A, 1tzz:B
88 4it1:D 427 302 0.1853 0.1593 0.2252 6.46e-07 4it1:A
89 4m0x:A 369 277 0.1826 0.1816 0.2419 8.54e-06 4m0x:B
90 2zad:A 344 286 0.1826 0.1948 0.2343 1.20e-05 3deq:A, 3deq:B, 3deq:C, 3deq:D, 3der:A, 3der:B, 3der:C, 3der:D, 3des:A, 3des:B, 3des:C, 3des:D, 3dfy:A, 3dfy:B, 3dfy:C, 3dfy:D, 3dfy:E, 3dfy:F, 3dfy:G, 3dfy:H, 3dfy:I, 3dfy:J, 3dfy:K, 3dfy:L, 3dfy:M, 3dfy:N, 3dfy:O, 3dfy:P, 2zad:B, 2zad:C, 2zad:D
91 3nfu:A 441 393 0.2534 0.2109 0.2366 1.58e-05 3nfu:B
92 2qvh:A 311 75 0.0627 0.0740 0.3067 6.36e-05 2qvh:B
93 3va8:A 427 294 0.1744 0.1499 0.2177 0.001
94 3n6h:B 432 299 0.1935 0.1644 0.2375 0.008 3n6h:A, 3n6h:C, 3n6h:D, 3pfr:A, 3pfr:B, 3pfr:C, 3pfr:D
95 5bof:A 434 94 0.0954 0.0806 0.3723 0.020 5boe:A, 5boe:B, 5bof:B
96 6o4n:A 422 82 0.0572 0.0498 0.2561 0.11 6o4n:B, 8w21:A, 8w21:B, 8w21:C, 8w21:E, 8w21:G, 8w21:H
97 7aih:BE 84 25 0.0300 0.1310 0.4400 2.3 7ane:BE
98 4as5:A 274 100 0.0736 0.0985 0.2700 3.2 4as5:B, 4as5:C, 4as5:D
99 8bxl:B 590 64 0.0518 0.0322 0.2969 4.3 8bxl:C, 8bxl:D, 8bxl:A, 8bxl:F, 8bxl:E
100 2e21:A 317 51 0.0490 0.0568 0.3529 6.3 2e21:C, 2e89:A, 2e89:B, 2e89:C, 2e89:D
101 3cp8:A 611 138 0.1035 0.0622 0.2754 6.6 3cp8:B, 3cp8:C, 3cp8:D
102 7jz2:A 481 36 0.0381 0.0291 0.3889 7.7 7jz2:E, 7jz2:I, 6wu6:A, 6wu6:E, 6wu6:I
103 5hww:A 128 31 0.0300 0.0859 0.3548 7.8 5hwv:A, 5hwv:B, 5hww:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218