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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SLIKNPILRGFNPDPSICRADTDYYIATSTFEWFPGVQIHHSKDLVNWHLVAHPLNRTSLLDMKGNPNSGGIWAPDLSYH
DGKFWLIYTDVKVTDGMWKDCHNYLTTCESVDGVWSDPITLNGSGFDASLFHDNDGKKYLVNMYWDQRTYNHNFYGIVLQ
EYSDKEKKLIGKAKIIYKGTDIKYTEGPHIYHIGDYYYLFTAEGGTTYEHSETVARSKNIDGPYEIDPEYPLLTSWHDPR
NSLQKCGHASLVHTHTDEWYLAHLVGRPLPVGNQPVLEQRGYCPLGRETSIQRIEWVDNWPRVVGGKQGSVNVEAPKIPE
VKWEKTYDEKDNFDSDKLNINFQSLRIPLTENIASLKAKKGNLRLYGKESLTSTFTQAFIARRWQSFKFDASTSVSFSPD
TFQQAAGLTCYYNTENWSTIQVTWNEDKGRVIDIVCCDNFHFDMPLKSNVIPIPKDVEYIHLKVEVRVETYQYSYSFDGI
NWSKVPAIFESRKLSDDYVQGGGFFTGAFVGINCIDITGNNKPADFDYFCYKEE

The query sequence (length=534) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1y7b:A 534 534 1.0000 1.0000 1.0000 0.0 1y7b:B, 1y7b:C, 1y7b:D, 1yi7:A, 1yi7:B, 1yi7:C, 1yi7:D
2 2exh:A 533 531 0.6629 0.6642 0.6667 0.0 2exh:B, 2exh:C, 2exh:D, 2exi:A, 2exi:B, 2exi:C, 2exi:D, 2exj:A, 2exj:B, 2exj:C, 2exj:D, 2exk:A, 2exk:B, 2exk:C, 2exk:D
3 5zqx:A 536 531 0.6049 0.6026 0.6083 0.0 5zqs:A, 5zqs:B, 5zqx:B, 5zqx:C, 5zqx:D
4 7k1r:A 536 532 0.5356 0.5336 0.5376 0.0 7k1r:B, 7k1r:C, 7k1r:D, 8uws:C, 8uws:D, 8uws:A, 8uws:B
5 6ms3:A 512 537 0.3427 0.3574 0.3408 3.16e-83 6ms2:A, 6ms3:B
6 5z5d:A 504 542 0.3464 0.3671 0.3413 1.52e-80 5z5f:A, 5z5h:A, 5z5i:A
7 5joz:A 507 548 0.3333 0.3511 0.3248 1.02e-78 5joz:B
8 5jox:A 502 536 0.3258 0.3466 0.3246 1.21e-71 5jox:B, 5joy:A, 5joy:B
9 3zxk:A 530 407 0.1948 0.1962 0.2555 3.11e-10 3zxk:B
10 4kc8:A 449 255 0.1273 0.1514 0.2667 6.47e-07
11 1uv4:A 291 234 0.1049 0.1924 0.2393 2.06e-06
12 3lv4:A 441 253 0.1292 0.1565 0.2727 3.41e-06 3lv4:B
13 1gye:B 315 241 0.1161 0.1968 0.2573 4.96e-06
14 5msx:C 440 150 0.0805 0.0977 0.2867 1.75e-05 5msx:A, 5msx:B
15 6b7k:A 290 230 0.1086 0.2000 0.2522 4.49e-05 6b7k:B, 6b7k:C, 6b7k:D
16 6a8i:A 318 239 0.0993 0.1667 0.2218 1.58e-04 6a8h:A, 6a8i:B, 3d5z:A, 3d61:A, 6f1g:A
17 3kst:A 291 248 0.1124 0.2062 0.2419 0.013 3kst:B
18 5m8e:A 323 332 0.1442 0.2384 0.2319 0.090 5m8e:B
19 5c0p:A 284 217 0.0880 0.1655 0.2166 0.28
20 8hcj:D 433 222 0.1011 0.1247 0.2432 0.46 8hcj:E, 8hcj:H, 8hcj:A, 8hcj:B, 8hcj:G, 8hcj:C, 8hcj:F
21 3opy:B 884 97 0.0487 0.0294 0.2680 0.55 3opy:D, 3opy:F, 3opy:H
22 5m8b:A 325 238 0.1086 0.1785 0.2437 0.63 5m8b:B
23 6xn1:B 333 130 0.0637 0.1021 0.2615 0.68 6xn1:A, 6xn2:B, 6xn2:A
24 5gll:A 331 84 0.0524 0.0846 0.3333 0.91 5glk:B, 5glm:A, 5glm:B, 5gln:A, 5gln:B, 5glo:A, 5glo:B, 5glp:A, 5glp:B, 5glq:A, 5glq:B, 5glr:A, 5glr:B
25 7z87:A 3689 36 0.0206 0.0030 0.3056 1.7
26 3qed:B 305 215 0.0993 0.1738 0.2465 1.9 3qed:A, 3qed:C, 3qed:D, 3qee:A, 3qee:B, 3qef:A, 3qef:B
27 6euf:A 472 181 0.0899 0.1017 0.2652 2.1 6euf:B, 6euf:C, 6euf:D
28 4ppv:A 246 94 0.0393 0.0854 0.2234 3.1 4ppu:A
29 4cot:A 443 258 0.1199 0.1445 0.2481 3.4 2x8s:A, 2x8s:B
30 3awm:A 407 54 0.0281 0.0369 0.2778 5.7 3awp:A, 3awq:A, 3vm4:A, 3vno:A, 3voo:A, 3vtj:A
31 3aki:A 448 144 0.0693 0.0826 0.2569 8.5 3akg:A, 3akh:A
32 4g8b:A 277 28 0.0243 0.0469 0.4643 8.6 4g8b:B, 4g8c:A, 4g8c:B, 4g9e:A, 4g9e:B
33 3vsz:C 482 30 0.0243 0.0270 0.4333 8.6 3vsz:A, 3vsz:B, 3vsz:E, 3vsz:F, 3vt0:A, 3vt0:B, 3vt0:C, 3vt0:E, 3vt0:F, 3vt1:B, 3vt1:C, 3vt1:E, 3vt1:F, 3vt1:A, 3vt2:A, 3vt2:B, 3vt2:C, 3vt2:D, 3vt2:E, 3vt2:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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