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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SLEWDNLGFSLLPWIRTGLDVMGFETMTPVQASTIPMLAGNKDVVVDSVTGSGKTAAFVIPVLEKVVKEEANTSKFKKAH
FHSLIIAPTRELSRQIESVVLSFLEHYPSDLFPIKCQLLVGTNEATVRDDVSNFLRNRPQILIGTPGRVLDFLQMPAVKT
SACSMVVMDEADRLLDMSFIKDTEKILRLLPKQRRTGLFSATMRSAGSDIFKTGLRNPVRITVNSSSLKLNYCVVNPAEK
LQLLVSILNNYKFKKCIVYFPTCVSVSYFYSFIQYLGKRNILVNEVEIFSLHGKLQTSARTKTLTAFTDSNSVLFTTDVA
ARGIDIPDVDLVIQLDPPTNTDMFMHRCGRTGRANRVGKAITFLNEGREEDFIPFMQVKNVELEELDLEVKGITANFYED
FRNWILEDRDRFDKGVKAYVAFIKYYSNHSATSIFRLQSLDYVGIAKLYGLFRLPRMPEITKYLNWLVDPPVNMDEYKYK
DKKREKERQETLKNISLINDKKKLKSELKKKNLAWSDKTLTKERKLERKEKMSLKRKAI

The query sequence (length=539) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7nac:x 539 539 1.0000 1.0000 1.0000 0.0 7nad:x, 7r72:x, 7r7a:x
2 8ia0:CW 540 497 0.3878 0.3870 0.4205 4.50e-110 8i9z:CW
3 5z3g:Y 438 445 0.2801 0.3447 0.3393 2.67e-66 6c0f:p, 6cb1:p, 8e5t:p, 7nac:D, 7ohr:D, 7ohs:D, 7ohv:D, 7ohw:D, 7ohx:D, 7r6q:D, 7r7a:D, 8v87:D
4 8i9z:CE 465 448 0.2783 0.3226 0.3348 9.95e-65 8i9p:CE, 8i9r:CE, 8i9t:CE, 8i9v:CE, 8i9w:CE, 8i9x:CE, 8i9y:CE, 8ia0:CE
5 8fky:SW 448 445 0.2672 0.3214 0.3236 1.91e-63 8fkp:SW, 8fkq:SW, 8fkr:SW, 8fks:SW, 8fkt:SW, 8fku:SW, 8fkv:SW, 8fkw:SW, 8fkx:SW, 3ly5:A
6 8esq:D 427 448 0.2635 0.3326 0.3170 9.88e-59 8esr:D, 8eth:D, 8eup:D, 8euy:D, 8ev3:D
7 8v83:D 423 449 0.2709 0.3452 0.3252 1.53e-58 6elz:D, 8v84:D
8 8eti:D 391 446 0.2468 0.3402 0.2982 2.26e-52
9 7pmq:C 458 377 0.2319 0.2729 0.3316 3.31e-52 7pli:A, 7pli:B, 7pli:J, 7pli:E, 7pli:F, 7pli:I, 7pmm:A, 7pmm:B, 7pmq:D, 7pmq:A, 7pmq:B
10 5dtu:A 404 366 0.2319 0.3094 0.3415 5.53e-52
11 8y6o:I 597 413 0.2356 0.2127 0.3075 2.94e-48 8qp8:G, 6qw6:5X, 6qx9:5X, 8r08:G
12 4bru:A 375 353 0.2096 0.3013 0.3201 4.66e-47
13 4ct4:B 378 385 0.1967 0.2804 0.2753 2.57e-46 5anr:B, 4ct4:D, 1vec:A, 2wax:C, 2way:A
14 8i9v:Cb 642 371 0.2301 0.1931 0.3342 1.58e-44 8i9t:Cb, 8i9w:Cb, 8i9x:Cb
15 3ex7:C 392 354 0.1967 0.2704 0.2994 1.86e-43 8c6j:7, 3ex7:H, 9fmd:7, 2hyi:C, 2hyi:I, 8i0w:u, 6icz:u, 2j0q:A, 2j0q:B, 2j0s:A, 2j0u:A, 6qdv:7, 2xb2:A, 2xb2:X, 5xjc:u, 5yzg:u, 7znj:A, 7znj:a, 7znj:F, 7znj:f, 7znj:K, 7znj:k
16 8fkv:NI 647 367 0.2152 0.1793 0.3161 2.34e-43 8fkt:NI, 8fku:NI, 8fkw:NI, 8fkx:NI, 8fky:NI
17 8v87:3 656 384 0.2226 0.1829 0.3125 3.37e-41 8v84:3
18 5elx:A 391 382 0.2226 0.3069 0.3141 4.80e-41 3peu:A, 3pev:A, 3pew:A, 3pey:A, 3rrm:A, 3rrn:A
19 6l5n:A 377 384 0.2115 0.3024 0.2969 1.46e-40 6l5m:A, 6l5m:B, 6l5m:C, 6l5m:D, 6l5m:E, 6l5n:B, 6l5o:A
20 4kbf:A 365 343 0.1948 0.2877 0.3061 1.20e-39 2gxq:A, 2gxs:A, 2gxs:B, 2gxu:A, 3mwk:B, 3mwl:B, 3nbf:A, 3nbf:B, 3nbf:C, 3nbf:D
21 6xki:A 378 393 0.2301 0.3280 0.3155 2.60e-39 5zbz:A, 5zc9:A
22 4d26:A 430 359 0.2022 0.2535 0.3036 3.46e-39 4d25:A
23 2db3:A 420 352 0.1985 0.2548 0.3040 1.29e-38 2db3:B, 2db3:C, 2db3:D
24 7liu:A 442 362 0.2078 0.2534 0.3094 5.64e-38 6cz5:A, 5e7j:A, 5e7m:A, 2i4i:A, 7liu:B, 4px9:A, 4px9:B, 4px9:C, 4pxa:A, 8ssw:A, 8ssw:B
25 4ljy:A 451 381 0.2078 0.2483 0.2940 1.32e-36 7oqb:p, 7oqe:p
26 2vso:A 366 340 0.1967 0.2896 0.3118 2.10e-36 1fuk:A, 2vso:B, 2vsx:A, 2vsx:B
27 5sup:B 383 402 0.1948 0.2742 0.2612 5.59e-36 5sup:A, 5sup:C, 5suq:A, 5suq:C
28 3i5x:A 509 397 0.2134 0.2259 0.2897 7.18e-36 4db2:C, 4db2:A, 4db2:B, 4db2:D, 4db4:A, 3i5y:A, 3i61:A, 3i62:A, 3sqw:A, 3sqx:A, 4tyn:A, 4tyw:A, 4tyy:A, 4tz0:A, 4tz6:A
29 8arp:C 445 355 0.1892 0.2292 0.2873 1.94e-35 8arp:A, 8arp:B, 8arp:D, 8arp:E, 8arp:F
30 6uv1:A 438 367 0.1929 0.2374 0.2834 2.71e-35 6uv1:B, 6uv2:A, 6uv3:A, 6uv4:A
31 6o5f:A 417 347 0.1985 0.2566 0.3084 5.64e-35 6o5f:B
32 4w7s:B 448 386 0.2096 0.2522 0.2927 1.28e-33
33 8enk:B 381 366 0.1725 0.2441 0.2541 1.34e-33 8enk:A, 1xtj:A, 7znk:P, 7znk:p
34 5h1y:B 245 210 0.1317 0.2898 0.3381 1.71e-31 5h1y:A
35 5gju:A 199 209 0.1447 0.3920 0.3732 1.88e-31
36 6b4i:F 426 395 0.1985 0.2512 0.2709 4.63e-30 6b4i:E, 6b4j:E, 6b4j:F, 6b4k:A, 6b4k:B, 3ews:A, 3ews:B, 3fht:A, 3fht:B, 3fmo:B, 3fmp:B, 3fmp:D, 3g0h:A
37 6aic:A 202 207 0.1336 0.3564 0.3478 9.46e-30
38 3ber:A 220 207 0.1280 0.3136 0.3333 6.63e-28
39 2pl3:A 232 208 0.1243 0.2888 0.3221 1.00e-23
40 7oi6:x 374 351 0.1874 0.2701 0.2877 1.34e-19
41 8tbx:A 458 203 0.1187 0.1397 0.3153 1.62e-18
42 8tbx:A 458 133 0.0779 0.0917 0.3158 2.31e-11
43 3fe2:A 234 204 0.1058 0.2436 0.2794 1.15e-16 3fe2:B
44 3b7g:A 205 202 0.1039 0.2732 0.2772 1.77e-16 3b7g:B, 2oxc:A, 2oxc:B
45 7am2:BW 447 395 0.1744 0.2103 0.2380 1.77e-16
46 3dkp:A 240 207 0.1058 0.2375 0.2754 5.29e-15
47 3iuy:A 213 202 0.1002 0.2535 0.2673 2.23e-11 3iuy:B
48 6yxy:EB 663 111 0.0631 0.0513 0.3063 1.13e-08 7aoi:XB, 6yxx:EB
49 6yxy:EB 663 179 0.0853 0.0694 0.2570 1.23e-07 7aoi:XB, 6yxx:EB
50 6s8r:A 167 163 0.0742 0.2395 0.2454 7.76e-08
51 2rb4:A 164 69 0.0464 0.1524 0.3623 2.54e-06
52 4q47:A 513 114 0.0575 0.0604 0.2719 0.002 4q47:B, 4q48:A, 4q48:B
53 7auc:A 493 77 0.0408 0.0446 0.2857 0.003
54 7aud:A 522 77 0.0408 0.0421 0.2857 0.003 7aud:E, 7aud:B, 7aud:C, 7aud:D, 7aud:F
55 4cgz:A 629 77 0.0408 0.0350 0.2857 0.004 4cdg:A, 4cdg:B, 4o3m:A
56 1oyw:A 516 153 0.0594 0.0620 0.2092 0.007 1oyy:A
57 1oyw:A 516 44 0.0241 0.0252 0.2955 3.9 1oyy:A
58 6crm:A 512 153 0.0594 0.0625 0.2092 0.013 4tmu:A
59 6crm:A 512 46 0.0278 0.0293 0.3261 0.68 4tmu:A
60 7zmq:A 443 45 0.0371 0.0451 0.4444 0.014 5lb3:B, 5lb3:E, 5lb5:A, 5lb5:B, 5lb5:C, 5lb5:D, 5lb8:A, 5lb8:D, 5lba:B, 5lba:A, 5lba:C, 5lba:D, 7zml:A, 7zml:B, 7zml:C, 7zml:D, 7zmm:B, 7zmm:A, 7zmm:C, 7zmm:D, 7zmn:A, 7zmn:B, 7zmo:A, 7zmo:B, 7zmp:A, 7zmp:B, 7zmq:B, 7zmr:A, 7zmr:B, 7zms:A, 7zmt:A, 7zmt:B, 7zmv:A, 7zmv:B, 7zmv:C, 7zmv:D
61 6p4f:C 436 122 0.0631 0.0780 0.2787 0.030 6p4f:A, 6p4w:A
62 8t5s:A 693 52 0.0390 0.0303 0.4038 0.046
63 8t5s:A 693 111 0.0408 0.0317 0.1982 0.64
64 8dfv:A 1664 43 0.0315 0.0102 0.3953 0.048
65 8dg5:A 1635 46 0.0353 0.0116 0.4130 0.051 8dg7:A
66 7yym:A 1281 129 0.0631 0.0265 0.2636 0.076 4ngb:A, 4ngc:A, 4ngg:A, 4nh3:A, 4nh5:A, 4nh6:A, 7yyn:A, 7zpi:A, 7zpj:A, 7zpk:A
67 6m6a:M 459 125 0.0594 0.0697 0.2560 0.085 6m6b:M
68 5v9x:A 772 382 0.1614 0.1127 0.2277 0.095
69 8dga:A 1629 42 0.0297 0.0098 0.3810 0.13
70 1z63:A 468 98 0.0538 0.0620 0.2959 0.15 1z63:B
71 5lst:A 617 107 0.0482 0.0421 0.2430 0.15
72 7tra:A 572 74 0.0390 0.0367 0.2838 0.16
73 6zns:A 635 84 0.0390 0.0331 0.2500 0.20
74 6znp:A 748 84 0.0390 0.0281 0.2500 0.25 6znq:A
75 6znq:B 711 84 0.0390 0.0295 0.2500 0.26 6znp:B
76 8rjf:A 424 129 0.0612 0.0778 0.2558 0.35 8rjf:B, 8rjf:C, 8rjf:D, 8rjf:E, 8rjf:F, 8rkd:F, 8rkd:A, 8rkd:C, 8rkd:D
77 7xti:k 434 154 0.0798 0.0991 0.2792 0.41 7xt7:k, 7xtd:k
78 5jb2:A 670 44 0.0278 0.0224 0.3409 0.57 5jaj:A, 5jbg:A
79 5jbj:A 627 44 0.0278 0.0239 0.3409 0.59
80 5zal:A 1314 40 0.0241 0.0099 0.3250 0.60 2eb1:A, 2eb1:B, 2eb1:C, 4ngd:A, 5zam:A
81 8wgh:O 89 28 0.0223 0.1348 0.4286 0.74
82 3tbk:A 524 48 0.0353 0.0363 0.3958 0.84
83 4a36:A 523 126 0.0705 0.0727 0.3016 1.5 4a36:B
84 5gan:B 1781 89 0.0427 0.0129 0.2584 1.5 4bgd:A, 5gao:B, 5gap:B, 5nrl:B, 5zwm:D, 5zwo:D
85 7a8r:A 531 79 0.0353 0.0358 0.2405 1.6 7a8r:B, 6jtz:A, 6jtz:B, 4u7d:A, 4u7d:B, 4u7d:D, 4u7d:C, 2v1x:A, 2v1x:B, 2wwy:B, 2wwy:A, 8yrs:B, 8yrs:A
86 7v6c:A 1540 75 0.0427 0.0149 0.3067 2.0
87 5eoc:J 214 50 0.0278 0.0701 0.3000 2.7 5eoc:H
88 4c4a:A 641 107 0.0482 0.0406 0.2430 4.3 6ogn:A
89 6l8n:A 810 119 0.0501 0.0333 0.2269 4.6
90 1ex0:B 716 61 0.0390 0.0293 0.3443 5.2 1ex0:A, 1ggy:A, 1ggy:B, 4kty:A, 4kty:B, 5mhl:A, 5mhl:B, 5mhn:A, 1qrk:A, 1qrk:B
91 3u44:A 1122 34 0.0223 0.0107 0.3529 5.5 3u4q:A
92 5mhn:B 685 61 0.0390 0.0307 0.3443 5.6 5mhm:A, 5mhm:B, 5mho:A, 5mho:B
93 6qv4:A 1666 176 0.0779 0.0252 0.2386 5.8 6qv3:A
94 4cej:A 1177 34 0.0223 0.0102 0.3529 5.9 4ceh:A, 4cei:A
95 7eld:A 1137 59 0.0278 0.0132 0.2542 6.2 7ele:A
96 6gaw:BC 571 62 0.0353 0.0333 0.3065 6.2 6gaz:BC, 6gb2:BC, 7po2:7, 8qrn:7, 6rw5:7
97 7w0b:A 1586 79 0.0427 0.0145 0.2911 6.6 7w0d:F
98 8hf0:A 1561 79 0.0427 0.0147 0.2911 6.7 8hf0:D, 8hf1:A, 8hf1:D, 8hf1:G, 7w0a:A, 7w0a:E, 7w0c:A, 7w0d:A, 7w0e:A, 7w0f:A
99 5f9h:G 653 55 0.0390 0.0322 0.3818 8.0 5e3h:A, 5f98:A, 5f98:C, 5f98:E, 5f98:G, 5f98:I, 5f98:K, 5f9h:A, 5f9h:C, 5f9h:E, 5f9h:I, 5f9h:K, 6gpg:A, 7jl3:A, 7jl3:C, 7jl3:E
100 3h9u:C 435 76 0.0408 0.0506 0.2895 8.4 3h9u:A, 3h9u:B, 3h9u:D
101 8h0s:B 171 48 0.0278 0.0877 0.3125 8.9 8h0s:D, 4poo:B
102 8jhz:A 2615 72 0.0408 0.0084 0.3056 9.0
103 8htu:O 90 28 0.0186 0.1111 0.3571 10.0 7ksq:O, 7ku5:O, 7xqp:O

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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