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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SLEKDKIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVINAAEKLVAIGCFCI
GTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGT
QLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVV
DIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYSDNGSTLSA
VNFPEVSLPLHGGRRLMHIHENRPGVLTALNKIFAEQGVNIAAQYLQTSAQMGYVVIDIEADEDVAEKALQAMKAIPGTI
RARLLY

The query sequence (length=406) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2p9e:A 406 406 0.9877 0.9877 0.9877 0.0 2p9c:A, 2p9c:B, 2p9e:B, 2p9e:C, 2p9e:D, 2p9g:A, 2p9g:B, 2pa3:A, 1psd:A, 1psd:B, 1sc6:A, 1sc6:B, 1yba:A, 1yba:B, 1yba:C, 1yba:D
2 1sc6:D 384 404 0.9360 0.9896 0.9406 0.0 1sc6:C
3 1wwk:A 304 311 0.3153 0.4211 0.4116 3.40e-61 1wwk:B
4 7dkm:A 306 304 0.2660 0.3529 0.3553 3.79e-52 7cvp:B, 6cwa:A, 6cwa:B, 7dkm:B, 7ewh:A, 7ewh:B, 2g76:A, 2g76:B, 5n53:B, 5n53:A, 5n6c:A, 5n6c:B, 5nzo:B, 5nzo:A, 5nzp:B, 5nzp:A, 5nzq:B, 5nzq:A, 5ofm:B, 5ofm:A, 5ofv:B, 5ofv:A, 5ofw:B, 5ofw:A, 6plf:A, 6plf:B, 6plg:A, 6plg:B, 6plg:C, 6plg:D, 6plg:E, 6plg:F, 6plg:G, 6plg:H, 6rih:A, 6rih:B, 6rj2:A, 6rj2:B, 6rj3:A, 6rj3:B, 6rj5:A, 6rj5:B, 6rj6:A, 6rj6:B, 7va1:B, 7va1:A, 7va1:C, 7va1:D
5 3dc2:A 526 269 0.2389 0.1844 0.3606 4.94e-45 3dc2:B, 3ddn:B
6 3dc2:A 526 63 0.0468 0.0361 0.3016 3.7 3dc2:B, 3ddn:B
7 2ekl:A 312 298 0.2488 0.3237 0.3389 1.45e-43
8 5aov:A 334 281 0.2192 0.2665 0.3167 5.13e-39
9 6bii:A 332 327 0.2438 0.2982 0.3028 6.24e-37 6bii:B
10 7cvp:A 254 226 0.1921 0.3071 0.3451 1.34e-36
11 4zgs:A 346 266 0.2143 0.2514 0.3271 5.30e-33 4zgs:B, 4zgs:C, 4zgs:D, 4zgs:E, 4zgs:F, 4zgs:G, 4zgs:H
12 3kb6:B 334 305 0.2315 0.2814 0.3082 1.25e-32 3kb6:A, 3kb6:C, 3kb6:D
13 3baz:A 311 249 0.2020 0.2637 0.3293 1.78e-32
14 6ttb:A 331 243 0.1995 0.2447 0.3333 5.76e-31
15 4prl:A 330 236 0.1847 0.2273 0.3178 9.85e-30 4prl:B
16 2gsd:A 399 267 0.2094 0.2130 0.3184 5.38e-29
17 8j3p:A 374 277 0.2143 0.2326 0.3141 2.70e-28 8j3o:A, 8j3o:B, 8j3o:C, 8j3o:D, 8j3p:B, 8j3p:C
18 4xkj:A 332 233 0.2069 0.2530 0.3605 1.74e-27 4xkj:B
19 1dxy:A 330 311 0.2217 0.2727 0.2894 2.43e-27
20 2dbq:A 333 266 0.2241 0.2733 0.3421 3.85e-27 2dbr:A, 2dbr:B, 2dbr:C, 2dbr:D, 2dbr:E, 2dbr:F, 2dbz:A, 2dbz:B
21 8ati:A 330 229 0.1847 0.2273 0.3275 4.38e-27 8ati:B, 8ati:C, 8ati:D, 4lcj:A, 4lcj:B, 4lcj:C, 4lcj:D, 4lcj:E, 4lcj:F, 4lcj:G, 4lcj:H, 2ome:A, 2ome:B, 2ome:C, 2ome:D, 2ome:E, 2ome:F, 2ome:G, 2ome:H, 6wkw:D, 6wkw:C, 6wkw:B, 6wkw:A
22 7arz:A 361 272 0.1921 0.2161 0.2868 7.02e-27
23 5z20:F 336 259 0.1970 0.2381 0.3089 7.35e-27 5z20:A, 5z20:B, 5z20:C, 5z20:D, 5z20:E
24 2yq5:C 331 239 0.1798 0.2205 0.3054 1.11e-26 2yq5:A, 2yq5:B, 2yq5:D
25 4njm:A 303 308 0.2094 0.2805 0.2760 4.16e-26 4njm:B, 4njo:A
26 6cdf:A 333 241 0.1798 0.2192 0.3029 5.05e-26 8ari:A, 8ari:G, 8ari:D, 8ari:F, 8ari:E, 8ari:J, 8ari:H, 8ari:K, 8ari:I, 8ari:P, 8ari:L, 8ari:M, 8ari:N, 8ari:T, 8ari:O, 8ari:Q, 8ari:R, 8ari:U, 8ari:S, 8ari:X, 8ari:B, 8ari:C, 8ari:V, 8ari:W, 6cdr:A, 1hku:A, 1hl3:A, 2hu2:A, 7kwm:A, 4lce:A, 1mx3:A, 4u6q:A, 4u6s:A, 6v89:A, 6v8a:A
27 8grv:A 336 230 0.1823 0.2202 0.3217 7.41e-25
28 6t9w:B 383 247 0.1847 0.1958 0.3036 9.60e-25 8bxx:AA, 8bxx:BB, 8bxx:CC, 8bxx:DD, 6t9w:A, 6t9w:C, 6t9x:B, 6t9x:A, 6t9x:C, 6t9x:D, 6tb6:B
29 3wr5:A 401 245 0.1872 0.1895 0.3102 1.64e-24 6juj:A, 6juj:B, 6juk:A, 6juk:B, 2nad:A, 2nad:B, 8oq2:A, 8oq2:B, 8oq2:C, 8oq2:D, 8oq2:E, 8oq2:F, 3wr5:B, 3wr5:C
30 2dld:A 337 231 0.1675 0.2018 0.2944 9.02e-24 2dld:B
31 3jtm:A 351 224 0.1700 0.1966 0.3080 1.35e-23 3n7u:A, 3n7u:B, 3n7u:C, 3n7u:D, 3n7u:E, 3n7u:F, 3n7u:G, 3n7u:H, 3n7u:I, 3n7u:J, 3n7u:K, 3n7u:L
32 4e5p:A 332 326 0.2241 0.2741 0.2791 1.85e-23 4e5k:A, 4e5k:B, 4e5k:C, 4e5k:D, 4e5m:A, 4e5m:B, 4e5n:A, 4e5n:B, 4e5n:C, 4e5n:D, 4e5n:E, 4e5n:F, 4e5n:G, 4e5n:H, 4e5p:B, 4e5p:C, 4e5p:D, 4e5p:E, 4e5p:F, 4ebf:A, 4ebf:B, 4ebf:C, 4ebf:D, 4nu5:A, 4nu5:B, 4nu6:A, 4nu6:B
33 7ya3:B 384 226 0.1675 0.1771 0.3009 1.94e-23 7ya3:A, 7ya4:A, 7ya4:B
34 2gcg:A 324 276 0.1970 0.2469 0.2899 2.66e-23 2gcg:B, 2gcg:C, 2gcg:D
35 5v6q:B 319 316 0.2241 0.2853 0.2880 5.00e-23 5j23:A, 5j23:B, 5j23:C, 5j23:D, 5v6q:A, 5v6q:C, 5v6q:D, 5v7g:A, 5v7g:B, 5v7g:C, 5v7g:D, 5v7n:A, 5v7n:B, 5v7n:C, 5v7n:D
36 1j49:A 332 231 0.1650 0.2018 0.2900 2.56e-22 1j49:B
37 6ih6:A 330 332 0.2488 0.3061 0.3042 4.96e-22 6ih3:A, 6ih5:B, 6ih6:B
38 4xyb:A 384 227 0.1700 0.1797 0.3040 6.31e-22 4xyb:B, 4xye:A, 4xye:B
39 4cuk:A 330 229 0.1700 0.2091 0.3013 1.87e-21 4cuk:D
40 6d4b:A 361 249 0.1700 0.1911 0.2771 8.43e-20 6d4b:B, 6d4c:A, 6d4c:B, 5dn9:A, 5dn9:B
41 6t8y:BBB 375 256 0.1970 0.2133 0.3125 2.44e-19 6t8y:AAA, 6t8y:CCC, 6t8y:DDD, 6t8z:AAA, 6t8z:BBB, 6t8z:CCC, 6t8z:DDD, 6t92:AAA, 6t92:BBB, 6t92:CCC, 6t92:DDD, 6t94:AAA, 6t94:BBB, 6t94:CCC, 6t94:DDD
42 2w2l:A 346 228 0.1749 0.2052 0.3114 2.50e-19 2w2l:B, 2w2l:C, 2w2l:D
43 5mh5:A 308 230 0.1601 0.2110 0.2826 9.49e-19 5mh5:B, 5mh6:A, 5mh6:B, 5mh6:C, 5mh6:D, 5mha:A, 5mha:B
44 5z21:B 331 229 0.1626 0.1994 0.2882 3.70e-18 5z21:A, 5z21:C, 5z21:D
45 5dt9:A 379 258 0.1872 0.2005 0.2946 9.68e-18
46 6p2i:A 307 249 0.1700 0.2248 0.2771 1.27e-16 6p2i:B
47 3oet:H 378 257 0.1847 0.1984 0.2918 9.19e-16 3oet:A, 3oet:B, 3oet:C, 3oet:D, 3oet:E, 3oet:F, 3oet:G
48 2o4c:A 380 235 0.1773 0.1895 0.3064 4.78e-15 2o4c:B
49 5vg6:B 315 187 0.1404 0.1810 0.3048 7.75e-15 5vg6:A, 5vg6:C, 5vg6:D, 5vg6:E, 5vg6:F, 5vg6:G, 5vg6:H, 5vg6:I, 5vg6:J
50 4zqb:B 316 220 0.1281 0.1646 0.2364 2.23e-12 4zqb:A
51 5bqf:A 317 199 0.1404 0.1798 0.2864 7.78e-11 5tsd:A, 5tsd:B, 4xcv:A
52 3kbo:A 312 190 0.1232 0.1603 0.2632 1.59e-10 3kbo:B, 3kbo:C, 3kbo:D
53 7jqh:A 313 206 0.1281 0.1661 0.2524 1.26e-08 7jqi:A, 7jqj:A, 6ovl:A, 6oxn:A, 6p35:A
54 4weq:A 316 195 0.1305 0.1677 0.2718 1.96e-07 4z0p:A
55 1qp8:A 301 174 0.1010 0.1362 0.2356 1.20e-06 1qp8:B
56 6cmz:A 462 98 0.0714 0.0628 0.2959 0.030 6cmz:B, 6cmz:C, 6cmz:D
57 6r8g:C 312 86 0.0567 0.0737 0.2674 0.17 6r8g:A, 6r8g:B, 6r8g:D, 6y91:A, 6y91:B, 6y91:C, 6y91:D
58 2f06:A 144 59 0.0443 0.1250 0.3051 0.26 2f06:B
59 2hjr:B 314 52 0.0493 0.0637 0.3846 0.46 2hjr:A, 2hjr:C, 2hjr:D, 2hjr:E, 2hjr:F, 2hjr:G, 2hjr:H, 2hjr:I, 2hjr:J, 2hjr:K, 2hjr:L
60 3om9:A 329 54 0.0419 0.0517 0.3148 0.48 3om9:B, 3om9:C, 3om9:D, 1pzf:A, 1pzf:B, 1pzf:C, 1pzf:D, 1pzg:A, 1pzg:B, 1pzg:C, 1pzg:D, 1pzh:A, 1pzh:B, 1pzh:C, 1pzh:D
61 6es9:A 545 137 0.0837 0.0624 0.2482 0.53 6es9:B
62 3gka:B 351 74 0.0567 0.0655 0.3108 1.6 3gka:A
63 5u8u:D 477 40 0.0419 0.0356 0.4250 1.6 1lpf:A, 1lpf:B, 5u8u:A, 5u8u:B, 5u8u:C, 5u8v:A, 5u8v:B, 5u8v:C, 5u8v:D, 5u8w:A, 5u8w:B, 5u8w:C, 5u8w:D
64 8fcj:I 494 60 0.0443 0.0364 0.3000 2.1 8fcj:K, 8fcu:I, 8fcu:J, 8fcu:K, 8fcu:L, 8fd3:I, 8ff4:I, 8ff4:J, 8ff4:K, 8ff4:L, 8ff5:I, 8ff5:J, 8ff5:K, 8ff5:L
65 4dyu:H 157 85 0.0616 0.1592 0.2941 2.2 4dyu:A, 4dyu:B, 4dyu:C, 4dyu:D, 4dyu:E, 4dyu:F, 4dyu:I, 4dyu:J, 4dyu:K, 4dyu:L
66 4plt:B 319 52 0.0493 0.0627 0.3846 2.7 4plh:A, 4plh:B, 4plh:C, 4plh:D, 4plt:A, 4plt:C, 4plt:D, 4plv:A, 4plv:B, 4plv:C, 4plv:D, 4plw:A, 4plw:B, 4plw:C, 4plw:D, 4ply:B, 4ply:A, 4ply:C, 4ply:D, 4ply:F, 4ply:E, 4ply:G, 4ply:H
67 5u1o:B 451 126 0.0690 0.0621 0.2222 3.3 5u1o:A, 5u1o:C, 5u1o:D
68 6jcz:C 331 68 0.0443 0.0544 0.2647 3.3 6jcw:A, 6jcw:B, 6jcw:C, 6jcw:D, 6jcw:E, 6jcw:F, 6jcw:G, 6jcw:H, 6jcw:I, 6jcw:J, 6jcw:K, 6jcw:L, 6jcz:A, 6jcz:B, 6jcz:D, 6jcz:E, 6jcz:F, 6jcz:G, 6jcz:H, 6jcz:I, 6jcz:J, 6jcz:K, 6jcz:L, 6jd1:A, 6jd1:B, 6jd1:C, 6jd1:D, 6jd1:E, 6jd1:F, 6jd1:G, 6jd1:H, 6jd1:I, 6jd1:J, 6jd1:K, 6jd1:L, 6jd2:A, 6jd2:B, 6jd2:C, 6jd2:D, 6jd2:E, 6jd2:F, 6jd2:G, 6jd2:H, 6jd2:I, 6jd2:J, 6jd2:K, 6jd2:L, 6kou:A, 6kou:B, 6kou:C, 6kou:D, 6kou:E, 6kou:F, 6kou:G, 6kou:H, 6kou:I, 6kou:J, 6kou:K, 6kou:L, 6kpa:A, 6kpa:B, 6kpa:C, 6kpa:D, 6kpa:E, 6kpa:F, 6kpa:G, 6kpa:H, 6kpa:I, 6kpa:J, 6kpa:K, 6kpa:L, 6kph:A, 6kph:B, 6kph:C, 6kph:D, 6kph:E, 6kph:F, 6kph:G, 6kph:H, 6kph:I, 6kph:J, 6kph:K, 6kph:L, 6kpi:A, 6kpi:B, 6kpi:C, 6kpi:D, 6kpi:E, 6kpi:F, 6kpi:G, 6kpi:H, 6kpi:I, 6kpi:J, 6kpi:K, 6kpi:L, 6kpj:A, 6kpj:B, 6kpj:C, 6kpj:D, 6kpj:E, 6kpj:F, 6kpj:G, 6kpj:H, 6kpj:I, 6kpj:J, 6kpj:K, 6kpj:L, 6kq4:A, 6kq4:B, 6kq4:C, 6kq4:D, 6kq4:E, 6kq4:F, 6kq4:G, 6kq4:H, 6kq4:I, 6kq4:J, 6kq4:K, 6kq4:L, 6kqj:A, 6kqj:B, 6kqj:C, 6kqj:D, 6kqj:E, 6kqj:F, 6kqj:G, 6kqj:H, 6kqj:I, 6kqj:J, 6kqj:K, 6kqj:L, 6kqk:A, 6kqk:B, 6kqk:C, 6kqk:D, 6kqk:E, 6kqk:F, 6kqk:G, 6kqk:H, 6kqk:I, 6kqk:J, 6kqk:K, 6kqk:L, 6kqo:A, 6kqo:B, 6kqo:C, 6kqo:D, 6kqo:E, 6kqo:F, 6kqo:G, 6kqo:H, 6kqo:I, 6kqo:J, 6kqo:K, 6kqo:L
69 2r9z:B 453 57 0.0443 0.0397 0.3158 3.6 2r9z:A, 2rab:A, 2rab:B
70 7aj0:A 501 109 0.0764 0.0619 0.2844 4.4 7aj0:B, 7aj0:C, 7aj0:D, 7aj0:E, 7aj0:F
71 1onf:A 439 53 0.0369 0.0342 0.2830 4.4
72 6toe:B 293 169 0.0911 0.1263 0.2189 4.4 6to4:A, 6to4:D, 6to4:B, 6to4:C, 6toe:A, 6toe:F, 6toe:C
73 6awa:A 475 31 0.0369 0.0316 0.4839 6.6 6awa:B, 5tr3:A, 5tr3:B
74 7aju:CJ 256 40 0.0419 0.0664 0.4250 6.7 6zqd:CJ, 6zqe:CJ
75 7ajt:CJ 282 40 0.0419 0.0603 0.4250 6.9 7d4i:5G, 7d5s:5G, 7d5t:5G, 7d63:5G, 6ke6:5G, 6lqp:5G, 6lqq:5G, 6lqr:5G, 6lqs:5G, 6lqt:5G, 6lqu:5G, 6lqv:5G, 7suk:SM, 5wlc:SM, 5wyj:MB, 5wyk:MB, 6zqa:CJ, 6zqb:CJ, 6zqc:CJ, 6zqf:CJ, 6zqg:CJ
76 7mq8:SM 290 46 0.0369 0.0517 0.3261 7.5 7mq9:SM, 7mqa:SM
77 3gvp:A 433 103 0.0542 0.0508 0.2136 7.7 3gvp:B, 3gvp:C, 3gvp:D, 3mtg:A, 3mtg:B
78 4plf:B 330 54 0.0443 0.0545 0.3333 7.9 4plc:A, 4plc:B, 4plc:C, 4plc:D, 4plf:A, 4plg:A, 4plg:B, 6vdj:A
79 3t7k:B 234 29 0.0296 0.0513 0.4138 9.0 3t7k:A
80 6h0a:A 339 78 0.0591 0.0708 0.3077 9.0 6g82:A, 6gmu:A, 4hho:A, 4hhq:A, 4q1u:A, 3sre:A, 3srg:A, 1v04:A
81 6bz0:A 469 52 0.0394 0.0341 0.3077 9.1 6bz0:B, 6bz0:C, 6bz0:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218