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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SLAFYIATFDIGTTEVKAALADRDGGLHFQRSIALETYGDGNGPVEQDAGDWYDAVQRIASSWWQSGVDARRVSAIVLSG
QMQNFLPLDQDHEPLHRAVLYSDKRPLKEAEEINARHGADNLWSALENPMTAASILPKLVFWRASFPQAFGRLRHVVLGA
KDYVVLRLTGRHATDRTNASTTGLYRPKDDAWHVELLADYGFSLDLMPRLLEPGEQVGGVSALAARQTGFVSGTPVLCGL
GDAGAATLGVGVLDDEDAYLHLGTTGWLARLTQTDPVGDMPVGTIFRLAGIIAGKTLQVAPVLNAGNILQWALTLVGHRP
GEDCAEYFHMAAAEVQGVTVPDGLLFVPYLHAERCPVELPAPRGALLGVTGATTRAQILLAVLEGAALSLRWCAELLGME
KVGLLKVVGGGARSEAWLRMIADNLNVSLLVKPDAHLHPLRGLAALAAVELEWSHSIQDFLREADLRSNILHPQPCDEGR
RRRKFERFKQCVETLGR

The query sequence (length=497) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3kzb:A 498 498 1.0000 0.9980 0.9980 0.0 3hz6:A
2 3ll3:A 492 434 0.2354 0.2378 0.2696 2.81e-34 3ll3:B
3 2itm:A 476 496 0.2696 0.2815 0.2702 4.45e-26 2itm:B
4 6k76:A 485 499 0.2394 0.2454 0.2385 5.89e-22 6k76:B
5 3ge1:A 499 508 0.2294 0.2285 0.2244 3.54e-16 3ge1:B, 3ge1:C, 3ge1:D
6 5ya1:A 478 439 0.2032 0.2113 0.2301 1.85e-14 5ya1:B, 5ya2:A, 5ya2:B
7 6zq4:F 512 457 0.2193 0.2129 0.2385 1.61e-13 6zq4:A, 6zq4:B, 6zq4:C, 6zq4:D, 6zq4:E, 6zq4:G, 6zq4:H, 6zq6:A, 6zq6:B, 6zq6:C, 6zq6:D, 6zq7:A
8 5azi:A 513 475 0.2173 0.2105 0.2274 1.71e-13 5azi:B, 5azi:C, 5azi:D, 5azj:A, 5azj:B, 5azj:C, 5azj:D, 5gn5:A, 5gn5:B, 5gn5:C, 5gn5:D, 5gn6:A, 5gn6:B, 5gn6:C, 5gn6:D, 6j9q:A, 6j9q:B, 6j9q:C, 6j9q:D, 6j9v:A, 6j9v:B, 6jaf:A, 3wxj:A, 3wxj:B, 3wxj:C, 3wxj:D, 3wxk:A, 3wxk:B, 3wxk:C, 3wxk:D, 3wxl:A, 3wxl:B, 3wxl:C, 3wxl:D
9 3h3n:X 501 506 0.2294 0.2275 0.2253 1.85e-13 3d7e:O, 3d7e:X, 3flc:O, 3flc:X, 3h3n:O, 3h3o:O, 3h3o:X, 3h3o:B, 3h3o:C, 3h45:X, 3h45:O, 3h45:C, 3h45:D, 3h46:X, 3h46:O, 1xup:O, 1xup:X
10 6ude:B 495 469 0.2193 0.2202 0.2324 2.65e-13 6ude:A, 6ude:C, 6ude:D
11 2w41:B 507 409 0.1751 0.1716 0.2127 9.53e-13 2w40:A, 2w40:B, 2w40:C, 2w40:D, 2w41:A
12 3i8b:A 506 471 0.2314 0.2273 0.2442 1.84e-12
13 1bu6:Y 499 508 0.2274 0.2265 0.2224 1.38e-09 1bo5:O, 1bo5:Z, 1bot:O, 1bot:Z, 1bu6:O, 1bu6:Z, 1bu6:X, 1bwf:Y, 1bwf:O, 3ezw:A, 3ezw:B, 3ezw:E, 3ezw:G, 3ezw:C, 3ezw:D, 3ezw:F, 3ezw:H, 1gla:G, 1glb:G, 1glc:G, 1gld:G, 1gle:G, 1glf:O, 1glf:X, 1glf:Y, 1glf:Z, 1glj:Y, 1glj:O, 1gll:Y, 1gll:O
14 5hux:A 429 474 0.2294 0.2657 0.2405 3.00e-08 5htp:A, 5hv7:A
15 3l0q:A 541 548 0.2334 0.2144 0.2117 1.38e-07
16 5htv:A 424 196 0.1127 0.1321 0.2857 2.47e-05 5htx:A
17 2cgj:A 479 135 0.0724 0.0752 0.2667 6.22e-04 2cgl:A, 2uyt:A
18 3qdk:A 546 368 0.1630 0.1484 0.2201 0.007
19 1gp6:A 349 72 0.0423 0.0602 0.2917 2.4 2brt:A, 1gp4:A, 1gp5:A
20 6uar:A 241 30 0.0262 0.0539 0.4333 2.6 6uas:A, 6uat:A, 6uau:A, 6ufl:A
21 3d2j:A 502 79 0.0402 0.0398 0.2532 3.9 3d2d:A, 3d2h:A, 4ec3:A, 3fw7:A, 3fw8:A, 3fw9:A, 3fwa:A, 3gsy:A, 4pzf:A, 4pzf:B, 4pzf:C, 4pzf:D
22 8tz0:A 505 19 0.0201 0.0198 0.5263 8.1 8tyz:A, 8tz0:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218