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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SKVSRDTLYEAVKEVLQGSKTKKRKFVETVELQISLKNYDPQKDKRFSGTVRLKSTPRPKFSVCLLGDQQHCDEAKAVEI
PHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENLVAKVDEVKSTIKFQMKKV
LCLAVAVGHVKMTEDELVYNIHLAINFLVSLLKKNWQNVRALYIKSTMGKPQRLY

The query sequence (length=215) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7a01:42 217 215 0.9442 0.9355 0.9442 1.71e-138 5aj0:Au, 8bhf:l1, 8btk:Bv, 6d90:K, 6d9j:K, 8fku:BB, 8fkv:BB, 8fkw:BB, 8fkx:BB, 8fky:BB, 8fl2:BB, 8fl3:BB, 8fl4:BB, 8g5y:Lz, 8g5z:Lz, 8g60:Lz, 8g61:Lz, 8g6j:Lz, 6gz3:Au, 6gz4:Au, 6gz5:Au, 6hcf:u3, 6hcj:w3, 6hcm:u3, 6hcq:w3, 8idy:t, 8ifd:2l, 8ife:2l, 8inf:q, 6ip5:2l, 3j7r:z, 5lks:Lz, 7ls1:L1, 7ls2:L1, 6mtb:u, 6mtc:u, 6mtd:u, 7nwg:w3, 7o7y:Bv, 7o7z:Bv, 7o80:Bv, 7o81:Bv, 8ohd:Lz, 8oj0:Lz, 8oj5:Lz, 8oj8:Lz, 6olg:Au, 8p2k:Bv, 6p5i:AK, 6p5j:AK, 6p5k:AK, 6p5n:AK, 8q87:Bv, 7qgg:Cz, 6qzp:Lz, 6sgc:B, 5t2c:l, 4ug0:Lz, 4v6x:Cz, 8xsx:Lz, 6y6x:Lz, 6z6l:Lz, 6z6m:Lz, 6z6n:Lz, 7zjw:Lx, 6zm7:Lz, 6zme:Lz, 6zmi:Lz, 6zmo:Lz, 6zvk:42
2 4v6w:Cz 217 215 0.7767 0.7696 0.7767 3.07e-111 6xu6:Cz, 6xu7:Cz, 6xu8:Cz
3 7zjx:Lx 169 212 0.7581 0.9645 0.7689 1.75e-95
4 4v3p:LA 216 215 0.6465 0.6435 0.6465 3.86e-92 4v7e:Cz
5 8pv4:Lr 214 207 0.6465 0.6495 0.6715 7.51e-88 8i9r:Lq, 8i9t:Lq, 8i9v:Lq, 8i9w:Lq, 8i9x:Lq, 8i9y:Lq, 8i9z:Lq, 8ia0:Lq, 8pv6:Lr, 8pv8:Lt, 8pvk:Lr
6 8c3a:l1 217 216 0.6279 0.6221 0.6250 6.34e-82 8c3a:L1, 8cq7:l1, 8cq7:L1, 8cqw:l1, 8cqw:L1, 8cre:l1, 8cre:L1, 8oeq:l1, 8oeq:L1
7 8bqd:BT 217 216 0.6140 0.6083 0.6111 4.20e-81 8aaf:w, 8agt:w, 8agu:w, 8agv:w, 8agw:w, 8agx:w, 8agz:w, 8bn3:B, 8bqx:BT, 8eub:E, 8evp:E, 8evq:E, 8evr:E, 8evs:E, 8evt:E, 8ewb:E, 8ewc:E, 6gqb:BA, 6gqv:BA, 8hfr:As, 5it7:qq, 3j0l:B, 3j0o:B, 3j0p:B, 3j0q:B, 3j6x:L1, 3j6y:L1, 3j77:L1, 3j78:L1, 5jcs:I, 8k2d:L1, 8k82:L1, 7nac:a, 2noq:G, 6oig:z, 7r7a:a, 7r7c:a, 6r84:L, 6r86:L, 6r87:L, 6tb3:BT, 6uz7:Bq, 4v4b:BA, 4v6i:BA, 4v7h:BA, 4v7r:BA, 4v7r:DA, 8v83:a, 8v84:a, 8v87:a, 4v91:t, 6woo:q, 6xiq:L1, 7zw0:LB
8 4v8m:BJ 214 215 0.5953 0.5981 0.5953 1.01e-79
9 8brm:Ln 211 213 0.4233 0.4313 0.4272 6.61e-55 8br8:Ln, 8bsi:Ln, 8bsj:Ln, 8btd:Ln, 8btr:Ln
10 6ylg:o 177 205 0.5070 0.6158 0.5317 5.81e-51 6ylh:o
11 5juo:E 171 216 0.4558 0.5731 0.4537 2.86e-42 5jup:E, 5jus:E, 5jut:E, 5juu:E
12 4v4n:AA 216 207 0.2698 0.2685 0.2802 3.19e-22 4v6u:BA
13 1u63:A 214 208 0.2744 0.2757 0.2837 2.66e-20 1i2a:A, 1u63:C
14 1mzp:A 217 209 0.2884 0.2857 0.2967 4.71e-18 8hku:AL1P, 8hky:AL1P, 8hkz:AL1P, 8hl1:AL1P, 8hl2:AL1P, 8hl3:AL1P, 8hl4:AL1P, 8hl5:AL1P, 4v49:B5, 4v4a:B5, 4v4g:B7, 4v4g:D7, 4v4g:F7, 4v4g:H7, 4v4g:J7, 4v65:BZ, 4v66:BZ
15 4d5y:u 210 188 0.2279 0.2333 0.2606 9.14e-14 4d67:u, 4ujc:Bu, 4ujd:Au, 4uje:Cu, 4v5z:B5
16 8i9p:CB 269 174 0.2279 0.1822 0.2816 7.00e-07 8i9r:CB, 8i9t:CB, 8i9v:CB, 8i9w:CB, 8i9x:CB, 8i9y:CB, 8i9z:CB, 8ia0:CB, 8pv1:CB, 8pv3:CB, 8pv4:CB, 8pv7:CB, 8pvk:CB, 6rxt:UZ, 6rxu:UZ, 6rxv:UZ, 6rxy:UZ, 6rxz:UZ
17 5jpq:k 182 150 0.1953 0.2308 0.2800 2.18e-06 5oql:Q
18 8fmw:AC 221 218 0.2512 0.2443 0.2477 6.92e-06
19 8fkp:SL 243 126 0.1442 0.1276 0.2460 1.45e-05 8fkq:SL, 8fkr:SL, 8fks:SL, 8fkt:SL, 8fku:SL, 8fkv:SL, 8fkw:SL, 8fkx:SL, 8fky:SL, 8fkz:SL, 8fl2:SL, 8fl6:SL, 8fla:SL, 8fld:SL, 8ine:u, 8inf:u, 8ipx:N, 8ipy:c, 8ir3:s
20 5dm6:0 224 199 0.2465 0.2366 0.2663 9.39e-05 5dm7:0
21 8esq:K 251 94 0.1163 0.0996 0.2660 0.001 8esr:K, 8etg:K, 8eth:K, 8eti:K, 8eup:K, 8euy:K, 8ev3:K
22 4qvi:A 229 202 0.2326 0.2183 0.2475 0.002 7a5f:n, 7a5g:n, 7a5j:n, 5a9z:AC, 5aa0:AC, 2hw8:A, 5imq:Z, 5imr:Z, 7lh5:BC, 7lh5:DC, 6n1d:AL01, 6n1d:BL01, 5npm:A, 2om7:K, 5ot7:f, 6q95:A, 4qg3:A, 4reo:A, 4u1u:B5, 4u1v:B5, 4u20:B5, 4u24:B5, 4u25:B5, 4u26:B5, 4u27:B5, 3u4m:A, 3u56:A, 3umy:A, 5uq7:C, 5uq8:C, 4v4p:AC, 4v4x:BC, 4v4y:BC, 4v4z:BC, 4v51:BC, 4v51:DC, 4v5a:BC, 4v5a:DC, 4v5c:BC, 4v5c:DC, 4v5d:BC, 4v5d:DC, 4v5e:BC, 4v5e:DC, 4v5f:BC, 4v5f:DC, 4v5g:BC, 4v5g:DC, 4v5k:BC, 4v5k:DC, 4v5l:BC, 4v5m:BC, 4v5n:BC, 4v5p:BC, 4v5p:DC, 4v5q:BC, 4v5q:DC, 4v5r:BC, 4v5r:DC, 4v5s:BC, 4v5s:DC, 4v68:BC, 4v6a:BC, 4v6a:DC, 4v7l:BC, 4v7l:DC, 4v7m:BC, 4v7m:DC, 4v8j:BC, 4v8j:DC, 4v8o:BC, 4v8q:AC, 4v8u:BC, 4v8u:DC, 4v8y:By, 4v8y:CL, 4v90:BC, 4v97:BC, 4v97:DC, 4v9h:BC, 4v9j:BC, 4v9j:DC, 4v9k:BC, 4v9k:DC, 4v9l:BC, 4v9l:DC, 4v9m:BC, 4v9m:DC, 4w29:BC, 4w29:DC, 4wf1:B5, 4woi:B5, 1zho:A, 1zho:C, 1zho:E, 1zho:G, 5zlu:Y
23 7msc:8 230 202 0.2326 0.2174 0.2475 0.41 7msh:8, 7msm:8, 7msz:8, 7mt2:8, 7mt3:8, 7mt7:8
24 8p5d:SU0 100 37 0.0651 0.1400 0.3784 2.2 8p60:SU0, 8p60:RU0, 7qca:SU0
25 7nkz:A 455 26 0.0465 0.0220 0.3846 3.4
26 3mu3:A 140 97 0.1116 0.1714 0.2474 4.4 3mu3:B
27 2bgg:B 394 58 0.0651 0.0355 0.2414 4.5 2w42:B
28 7rdq:F 349 56 0.0651 0.0401 0.2500 5.5 2a68:F, 2a68:P, 2a69:F, 2a69:P, 6cuu:F, 5d4c:F, 5d4c:P, 5d4d:F, 5d4d:P, 5d4e:F, 5d4e:P, 5e17:F, 5e18:F, 7eh0:F, 7eh1:F, 7eh2:F, 7eh2:P, 4g7h:F, 4g7h:P, 4g7o:F, 4g7o:P, 4g7z:F, 4g7z:P, 5i2d:F, 5i2d:Q, 1iw7:F, 1iw7:P, 4ki2:A, 4ki2:B, 6kqd:F, 6kqd:P, 6kqe:F, 6kqf:F, 6kqg:F, 6kqh:F, 6kql:F, 6kqm:F, 6kqn:F, 1ku7:A, 6l74:F, 6lts:F, 7mlb:F, 7mli:F, 7mlj:F, 3n97:A, 4oin:F, 4oio:F, 4oip:F, 4oiq:F, 4oir:F, 6ovr:F, 6ovy:F, 6ow3:F, 6oy5:F, 6oy6:F, 6oy7:F, 6p70:F, 6p71:F, 4q4z:F, 4q5s:F, 1rio:H, 1smy:F, 5tjg:F, 3ugo:A, 3ugp:A, 5vo8:F, 5voi:F, 8w8n:F, 8w8o:F, 8w8p:F, 6wox:F, 6woy:F, 5x21:F, 5x22:F, 5x22:P, 4xln:F, 4xln:L, 4xlp:F, 4xlp:L, 4xlq:F, 4xlq:L, 4xlr:F, 4xlr:L, 4xls:F, 4xls:L
29 7oik:A 4426 67 0.0977 0.0047 0.3134 5.7 7oim:A, 6tax:A, 6tay:A
30 8ok9:A 430 50 0.0605 0.0302 0.2600 8.8 2bgg:A, 8pvv:A, 8qg0:A, 6t5t:A, 6tuo:A, 2w42:A, 6xu0:A, 6xu0:B, 6xup:A, 6xup:B, 1ytu:A, 1ytu:B
31 5ylz:I 517 20 0.0465 0.0193 0.5000 9.4
32 7dco:J 554 20 0.0465 0.0181 0.5000 9.8 5y88:I
33 6j6g:d 566 20 0.0465 0.0177 0.5000 9.8 7b9v:S, 6j6h:d, 6j6n:d, 6j6q:d, 5lqw:R

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218