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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SKVPYYKFPSVTKLRIRPPAHALDEAYIAKYNLAISRMKDLDKTQPDNPIGFKQQANIHCAYQVHNSWLFFPFHRWYLYF
YERILGSLIDDPTFGLPFWNWDHPKGMRFPPMFDVPGTALYDERRGDQIHNGNFIDLGSFGDQVETTQLQLMTNNLTLMY
RQLVTNSPCPLMFFGGPSTVEAAGTVENIPHSPVHIWVGTRRGSVLPDGKISNGEDMGNFYSAGLDPLFYCHHSNVDRMW
NEWKATGGKRTDLQNKDWLNSEFFFYDENGNPFKVRVRDCLDTKKMGYDYQPTATPWRNFKPKTKASAGKVNTGSIPPES
QVFPLAKLDKAISFSINRPASSRTQQEKNAQEEVLTFNAIKYDNRDYIRFDVFLNVDNNVNANELDKAEFAGSYTSLTAT
ATLRLAITELLEDIGLEDEDTIAVTLVPKKGDISIGGVEIKLAD

The query sequence (length=444) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6hqi:A 444 444 1.0000 1.0000 1.0000 0.0
2 6els:A 459 471 0.4685 0.4532 0.4416 6.93e-134 6elt:A, 6elv:A
3 4z11:A 513 484 0.4257 0.3684 0.3905 5.89e-107 4z0y:A, 4z0y:B, 4z0y:D, 4z0y:C, 4z0z:A, 4z0z:B, 4z0z:C, 4z0z:D, 4z10:A, 4z10:C, 4z10:B, 4z10:D, 4z10:E, 4z10:F, 4z11:B, 4z11:C, 4z11:D, 4z12:A, 4z12:B, 4z13:A, 4z13:B, 4z14:D, 4z14:B, 4z14:H, 4z14:F, 4z14:C, 4z14:E, 4z14:G, 4z14:A
4 1bug:A 336 317 0.3491 0.4613 0.4890 7.04e-99 1bug:B
5 5ce9:A 339 306 0.3333 0.4366 0.4837 4.68e-98 5ce9:B
6 8bbq:A 324 334 0.1779 0.2438 0.2365 1.57e-11 8bbq:B, 8bbr:A, 8bbr:B
7 4bed:A 1664 190 0.1081 0.0288 0.2526 4.22e-08 4bed:C
8 4bed:A 1664 228 0.1261 0.0337 0.2456 3.49e-05 4bed:C
9 4bed:A 1664 62 0.0518 0.0138 0.3710 0.001 4bed:C
10 4bed:A 1664 56 0.0428 0.0114 0.3393 0.049 4bed:C
11 5zre:B 474 114 0.0856 0.0802 0.3333 1.11e-07 5zre:A, 5zre:C
12 5zre:B 474 55 0.0428 0.0401 0.3455 0.16 5zre:A, 5zre:C
13 8hpi:A 289 255 0.1419 0.2180 0.2471 1.88e-07 4d87:A, 4d87:B, 6ei4:A, 6ei4:B, 4hd4:A, 4hd4:B, 4hd6:A, 4hd6:B, 4hd7:A, 4hd7:B, 8hpi:B, 5i38:A, 5i38:B, 5i3a:A, 5i3a:B, 5i3b:A, 5i3b:B, 4j6t:A, 4j6t:B, 4j6v:A, 4j6v:B, 3nm8:A, 3nm8:B, 3npy:A, 3npy:B, 3nq0:A, 3nq0:B, 3nq1:A, 3nq1:B, 3nq5:A, 3nq5:B, 3ntm:A, 3ntm:B, 5oae:A, 5oae:B, 4p6r:A, 4p6r:B, 4p6s:A, 4p6s:B, 4p6t:A, 4p6t:B, 6qxd:A, 6qxd:B
14 4bed:B 1734 236 0.1351 0.0346 0.2542 4.04e-07 4bed:D, 3qjo:A, 3qjo:B
15 4bed:B 1734 57 0.0450 0.0115 0.3509 0.005 4bed:D, 3qjo:A, 3qjo:B
16 4bed:B 1734 69 0.0473 0.0121 0.3043 0.010 4bed:D, 3qjo:A, 3qjo:B
17 4bed:B 1734 35 0.0225 0.0058 0.2857 3.1 4bed:D, 3qjo:A, 3qjo:B
18 6z1s:A 381 238 0.1351 0.1575 0.2521 1.67e-06
19 4yd9:B 825 325 0.1599 0.0861 0.2185 1.86e-06 4yd9:E, 4yd9:H, 4yd9:K, 4yd9:N, 4yd9:Q, 4yd9:T, 4yd9:W, 4yd9:Z, 4yd9:c
20 4yd9:B 825 257 0.1239 0.0667 0.2140 3.35e-05 4yd9:E, 4yd9:H, 4yd9:K, 4yd9:N, 4yd9:Q, 4yd9:T, 4yd9:W, 4yd9:Z, 4yd9:c
21 6j2u:B 273 206 0.1126 0.1832 0.2427 1.86e-06
22 1js8:A 382 232 0.1284 0.1492 0.2457 4.12e-06 1js8:B
23 5z0f:A 279 203 0.1126 0.1792 0.2463 7.47e-06 2ahk:A, 2ahl:A, 3aws:A, 3awt:A, 3awu:A, 3awv:A, 3aww:A, 3awx:A, 3awy:A, 3awz:A, 3ax0:A, 7cit:A, 7ciy:A, 1wx2:A, 1wx4:A, 5z0d:A, 5z0e:A, 5z0g:A, 5z0h:A, 5z0i:A, 5z0j:A, 5z0k:A, 5z0l:A, 5z0m:A, 2zmx:A, 2zmy:A, 2zmz:A, 2zwd:A, 2zwe:A, 2zwf:A, 2zwg:A
24 4yd9:A 1656 184 0.1104 0.0296 0.2663 1.72e-05 4yd9:D, 4yd9:G, 4yd9:J, 4yd9:M, 4yd9:P, 4yd9:S, 4yd9:V, 4yd9:Y, 4yd9:b
25 4yd9:A 1656 76 0.0495 0.0133 0.2895 1.46e-04 4yd9:D, 4yd9:G, 4yd9:J, 4yd9:M, 4yd9:P, 4yd9:S, 4yd9:V, 4yd9:Y, 4yd9:b
26 4yd9:A 1656 200 0.0991 0.0266 0.2200 3.46e-04 4yd9:D, 4yd9:G, 4yd9:J, 4yd9:M, 4yd9:P, 4yd9:S, 4yd9:V, 4yd9:Y, 4yd9:b
27 4yd9:A 1656 57 0.0428 0.0115 0.3333 0.001 4yd9:D, 4yd9:G, 4yd9:J, 4yd9:M, 4yd9:P, 4yd9:S, 4yd9:V, 4yd9:Y, 4yd9:b
28 5zrd:A 534 60 0.0541 0.0449 0.4000 2.01e-05 5zrd:B, 5zrd:C, 5zrd:D
29 5zrd:A 534 40 0.0338 0.0281 0.3750 0.82 5zrd:B, 5zrd:C, 5zrd:D
30 4yd9:L 366 60 0.0518 0.0628 0.3833 1.52e-04 4yd9:C, 4yd9:a, 4yd9:F, 4yd9:R, 4yd9:I, 4yd9:O, 4yd9:U, 4yd9:X, 4yd9:d
31 1lnl:A 408 56 0.0428 0.0466 0.3393 0.001 1lnl:B, 1lnl:C
32 6jua:A 533 113 0.0698 0.0582 0.2743 0.002 6jub:A, 6jud:A
33 6ju4:B 560 113 0.0698 0.0554 0.2743 0.002 6ju4:A, 6ju5:A, 6ju5:B, 6jua:B, 6jub:B, 6juc:A, 6juc:B, 6jud:B, 3w6w:B
34 3w6w:A 583 113 0.0698 0.0532 0.2743 0.003 6ju7:A, 6ju7:B, 6ju8:A, 6ju8:B, 6ju9:A, 6ju9:B
35 8tnv:A 393 62 0.0450 0.0509 0.3226 0.018 8tnv:B
36 4j3r:A 372 223 0.1284 0.1532 0.2556 0.022 6gsg:A, 4j3p:A, 4j3q:A, 4j3q:B, 5or3:A, 5or3:B, 5or3:C, 5or3:D, 5or4:A, 5or4:B, 5or4:C, 5or4:D
37 5m6b:C 514 63 0.0518 0.0447 0.3651 0.031
38 4oua:B 557 63 0.0518 0.0413 0.3651 0.035 5m6b:B, 5m6b:A, 5m6b:D, 4oua:A
39 2y9w:A 391 74 0.0518 0.0588 0.3108 0.083 2y9w:B, 2y9x:A, 2y9x:B, 2y9x:C, 2y9x:D
40 9ey8:DA 450 37 0.0270 0.0267 0.3243 0.099 9ey5:A, 9ey6:A, 9ey7:A, 9ey8:AA, 9ey8:BA, 9ey8:CA, 5m8l:A, 5m8l:C, 5m8l:B, 5m8l:D, 5m8m:A, 5m8m:B, 5m8m:C, 5m8m:D, 5m8n:A, 5m8n:C, 5m8n:D, 5m8n:B, 5m8o:B, 5m8o:C, 5m8o:A, 5m8o:D, 5m8p:A, 5m8p:B, 5m8p:C, 5m8p:D, 5m8q:A, 5m8q:C, 5m8q:D, 5m8q:B, 5m8r:A, 5m8r:B, 5m8r:C, 5m8r:D, 5m8s:A, 5m8s:B, 5m8s:D, 5m8s:C, 5m8t:A, 5m8t:B, 5m8t:C, 5m8t:D
41 2bhp:A 516 81 0.0495 0.0426 0.2716 0.65 2bhp:B, 2bhq:A, 2bhq:B, 2bja:A, 2bja:B, 2bjk:A, 2bjk:B, 2ehq:A, 2ehq:B, 2ehu:A, 2ehu:B, 2eii:A, 2eii:B, 2eit:A, 2eit:B, 2eiw:A, 2eiw:B, 2ej6:A, 2ej6:B, 2ejd:A, 2ejd:B, 2ejl:A, 2ejl:B, 2j40:A, 2j40:B, 2j5n:A, 2j5n:B
42 1fhr:A 158 110 0.0653 0.1835 0.2636 1.6 1j4k:A, 1j4l:A, 1k2m:A, 1k2n:A
43 1j4u:A 149 34 0.0293 0.0872 0.3824 1.8 1j4u:B, 1j4u:C, 1j4u:D, 1vbo:A, 1vbo:B, 1vbo:C, 1vbo:E, 1vbo:G, 1vbo:H, 1vbo:D, 1vbo:F, 1vbp:A, 1vbp:B
44 1fch:A 302 69 0.0450 0.0662 0.2899 2.1 1fch:B, 9gag:A
45 2vyn:D 334 65 0.0450 0.0599 0.3077 2.3 2vyv:D
46 2vss:B 247 90 0.0586 0.1053 0.2889 7.5 6l3p:A, 6l3p:B, 2vss:D, 2vss:E, 2vss:F, 2vsu:A, 2vsu:B, 2vsu:D, 2vsu:E, 2vsu:F
47 3bnk:B 187 69 0.0450 0.1070 0.2899 8.5 3bnk:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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