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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SKSTAEIRQAFLDFFHSKGHQVVASSSLVPHNDPTLLFTNAGMNQFKDVFLGLDKRNYSRATTSQRCVRAGGKHNDLENV
GYTARHHTFFEMLGNFSFGDYFKLDAILFAWLLLTSEKWFALPKERLWVTVYESDDEAYEIWEKEVGIPRERIIRIGDNK
GAPYASDNFWQMGDTGPCGPCTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNIVFMQFNRQADGTMEPLPKPSVDTAMGL
ERIAAVLQHVNSNYDIDLFRTLIQAVAKVTGATDLSNKSLRVIADHIRSCAFLIADGVMPSNENRGYVLRRIIRRAVRHG
NMLGAKETFFYKLVGPLIDVMGSAGEDLKRQQAQVEQVLKTEEEQFARTLERGLALLDEELAKLSGDTLDGETAFRLYDT
YGFPVDLTADVCRERNIKVDEAGFEAAMEEQRRRAREASGF

The query sequence (length=441) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3hxu:A 441 441 0.9977 0.9977 0.9977 0.0 3hxv:A, 3hxw:A, 3hxx:A, 3hxy:A, 3hxz:A, 3hxz:B, 3hxz:C, 3hxz:D, 3hy0:A, 3hy0:B, 3hy1:A
2 1yfr:A 448 448 0.5351 0.5268 0.5268 2.47e-164 1yfr:B, 1yfs:A, 1yfs:B, 1ygb:A
3 5knn:A 450 465 0.4898 0.4800 0.4645 7.61e-130 5knn:B, 5knn:C, 5knn:D, 5knn:E, 5knn:F, 5knn:G, 5knn:H, 5v59:A, 4xem:A, 4xeo:A, 4xeo:B
4 2zze:A 744 480 0.2630 0.1559 0.2417 4.13e-25 2zze:B, 2zzf:A, 2zzg:A, 2zzg:B
5 3wqy:A 905 469 0.2540 0.1238 0.2388 2.25e-21 3wqy:B, 3wqz:A, 3wqz:B, 2ztg:A
6 1vrg:A 515 37 0.0295 0.0252 0.3514 0.28 1vrg:B, 1vrg:C, 1vrg:D, 1vrg:E, 1vrg:F
7 1htt:A 366 38 0.0363 0.0437 0.4211 2.0 1htt:B, 1htt:C, 1htt:D, 1kmm:B, 1kmm:D, 1kmn:B, 1kmn:D
8 1kmm:C 387 38 0.0363 0.0413 0.4211 2.1 2el9:A, 2el9:B, 2el9:C, 2el9:D, 1kmm:A, 1kmn:A, 1kmn:C
9 2h7f:X 314 72 0.0408 0.0573 0.2500 3.1 2h7g:X, 3igc:A
10 4ix3:B 350 77 0.0544 0.0686 0.3117 3.2 4ix3:A, 4ix4:A, 4ix4:B, 4ix5:A, 4ix5:B, 4ix6:A, 4ix6:B
11 7lu4:B 977 53 0.0476 0.0215 0.3962 4.0
12 3rgl:A 292 24 0.0295 0.0445 0.5417 7.2 3rgl:B, 3ufg:A, 3ufg:B
13 8fmw:AU 115 42 0.0340 0.1304 0.3571 7.9 8fn2:U
14 3nbx:X 481 49 0.0385 0.0353 0.3469 7.9 6q7l:V, 6q7l:W, 6q7l:X, 6q7l:Y, 6q7l:Z, 6q7m:V, 6q7m:W, 6q7m:X, 6q7m:Y, 6q7m:Z, 6sza:B, 6sza:C, 6sza:A, 6sza:D, 6sza:E, 6sza:F, 6szb:D, 6szb:E, 6szb:C, 6szb:B, 6szb:A, 6szb:F
15 8snb:8K 322 48 0.0363 0.0497 0.3333 8.8
16 5abs:A 66 38 0.0272 0.1818 0.3158 8.9
17 1zrm:A 220 31 0.0249 0.0500 0.3548 9.1

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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