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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SKPRILLMGLRRSGKNSIQKVVFHNSSFVNFQIWEMIFRGTGALIYVIDAQDDYMEALTRLHITVSKAYKVNPDMNFEVF
IHKVDGLSDDHKIETQRDIHQRANDDLADAGLEKLHLSFYLTSIYDHSIFEAFSKVVQKLIPQLPTLENLLNIFISNSGI
EKAFLFDVVSKIYIATDSSPVDMQSYELCCDMIDVVIDVSCIYGLKEDGSGSAYDKESMAIIKLNNTTVLYLKEVTKFLA
LVCILREESFERKGLIDYNFHCFRKAIHEVFE

The query sequence (length=272) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6s6d:C 284 282 1.0000 0.9577 0.9645 0.0
2 6ulg:G 310 308 0.9926 0.8710 0.8766 0.0 8dhb:A, 3llu:A, 6nzd:G, 2q3f:A, 2q3f:B, 6s6a:C, 6s6a:D, 6s6d:D, 6sb0:D, 6sb0:J, 6sb2:D, 6sb2:J, 7t3b:E, 7t3c:E, 6u62:C, 7ux2:C, 7ux2:J, 7uxc:E, 7uxc:L, 7uxh:G, 7uxh:N, 7uxh:W, 7uxh:d, 6wj2:G, 6wj3:G
3 8fw5:E 285 282 0.6213 0.5930 0.5993 2.98e-118
4 4arz:B 304 309 0.5000 0.4474 0.4401 1.24e-84 6jwp:B, 3r7w:B, 3r7w:D
5 8fw5:D 301 221 0.2132 0.1927 0.2624 6.47e-10
6 6nzd:F 227 173 0.1765 0.2115 0.2775 8.52e-10
7 6ces:A 300 215 0.2059 0.1867 0.2605 1.44e-09 8dhb:B, 6s6a:A, 6s6a:B, 6s6d:A, 6s6d:B, 6sb0:C, 6sb0:I, 6sb2:C, 6sb2:I, 7t3a:K, 7t3b:D, 7t3c:D, 7t3c:K, 6u62:B, 6ulg:F, 7ux2:B, 7ux2:I, 7uxc:D, 7uxc:K, 7uxh:F, 7uxh:M, 7uxh:V, 7uxh:c, 6wj2:F, 6wj3:F
8 4arz:A 291 229 0.1912 0.1787 0.2271 1.39e-06 6jwp:A, 6jwp:F, 3r7w:A, 3r7w:C
9 7rll:B 177 83 0.0919 0.1412 0.3012 0.24 7rll:A
10 3aq4:A 170 83 0.0882 0.1412 0.2892 0.44 3aq4:B
11 4y0v:A 165 72 0.0735 0.1212 0.2778 1.4 4y0v:B, 4ylg:A, 4ylg:B
12 3o47:A 289 73 0.0772 0.0727 0.2877 2.1 4c0a:C, 4c0a:D, 4c0a:G, 4c0a:H, 6cm9:C, 6cm9:H, 6cri:C, 6cri:H, 6cri:K, 6cri:U, 6cri:L, 6cri:V, 6d83:C, 6d83:H, 6d84:C, 6d84:H, 6d84:I, 6d84:N, 6dff:C, 6dff:H, 7dn8:D, 7dn8:B, 7dn8:F, 7dn8:H, 7dn9:B, 7dn9:D, 7dn9:F, 7dn9:H, 3dwd:A, 3dwd:B, 4hmy:C, 6ii6:C, 6ii6:D, 1j2j:A, 2j59:A, 2j59:B, 2j59:C, 2j59:D, 2j59:E, 2j59:F, 7mge:E, 1o3y:A, 1o3y:B, 3o47:B, 8p50:B, 7r4h:C, 7r4h:H, 1r8q:A, 1r8q:B, 1r8s:A, 1re0:A, 1rrf:A, 1rrg:A, 1rrg:B, 1s9d:A, 8sdw:A, 1u81:A, 7wqy:A, 7wqy:B
13 6pta:A 165 73 0.0735 0.1212 0.2740 2.2 6pta:B, 6pta:C, 6pta:D, 5uf8:A, 5uf8:B, 5uf8:C
14 8oun:A 181 45 0.0478 0.0718 0.2889 3.8 8oum:A, 8oum:B, 8oum:C, 8oum:D, 8oum:E, 8oun:B
15 1dek:A 241 56 0.0699 0.0788 0.3393 4.2 1dek:B, 1del:A, 1del:B
16 5uf8:D 160 74 0.0699 0.1187 0.2568 4.3
17 7sl4:A 786 104 0.0919 0.0318 0.2404 6.0 8dtm:B
18 7sl6:A 819 104 0.0919 0.0305 0.2404 6.5 7mqs:F, 7mqs:E, 7sl1:A, 7sl1:B, 7sl2:A, 7sl2:B, 7sl6:B, 7sl7:A, 7sl7:B
19 2b6h:A 171 73 0.0735 0.1170 0.2740 6.7
20 5de3:A 166 78 0.0882 0.1446 0.3077 7.1 5di3:A
21 9bh5:CX 119 63 0.0699 0.1597 0.3016 7.3 9cai:CX
22 6a8d:A 181 78 0.0699 0.1050 0.2436 8.6
23 3lrp:A 181 92 0.0882 0.1326 0.2609 9.0
24 2x77:A 181 80 0.0772 0.1160 0.2625 9.4 2x77:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218